Long-read sequencing uncovers key regulatory genes involved in the differentiation of preadipocytes of Chinese red steppe cattle by Wenwen Fang, Shaoying Yang, Xuanyu Li, Asadollahpour Nanaei, Yu Liu, Yang Cao, Cheng Xiao, Xin Li, Haiguo Jin, Yumin Zhao, Yang Cao

“…At the same time, based on diverse expression patterns in 3 periods (early, middle and late), we identified 754 significantly differentially expressed genes (DEGs) and 932 significantly differentially expressed transcripts (DETs) in the first contrast group (0d_vs_4d), 197 significantly DEGs and 297 significantly DETs in the second contrast group (0d_vs_8d), 465 and 555 significantly DEGs and DETs in the third contrast group (4d_vs_8d). …”
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Seed microbiomes promote Astragalus mongholicus seed germination through pathogen suppression and cellulose degradation by Da Li, Weimin Chen, Wen Luo, Haofei Zhang, Yang Liu, Duntao Shu, Gehong Wei

“…The co-occurrence network patterns revealed that the microbial communities within germinated and ungerminated seeds presented distinct structures. …”
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Influences on limited antimicrobial use in small-scale freshwater aquaculture farms in central Thailand by Nour Alhusein, Boonrat Chantong, Sarin Suwanpakdee, Anuwat Wiratsudakul, Virginia C. Gould, Kantima Wichuwaranan, Kornrawan Poonsawad, Varapon Montrivade, Nutcha Charoenboon, Luechai Sringernyuang, Matthew B. Avison, Helen Lambert, Walasinee Sakcamduang, Henry Buller, Kristen K. Reyher

“…IntroductionRecent years have shown substantial growth both in the scale and the spread of freshwater aquaculture in Thailand, raising concerns about potential widespread unsustainable use of antimicrobials.MethodsThis mixed-methods study used surveys and qualitative interviews to examine conditions of freshwater aquaculture farming in central Thailand in relation to animal health, disease management and patterns of antimicrobial use.ResultsFreshwater aquaculture in this area of Thailand was largely a domestic venture operated as a source of additional household income to increase financial security. …”
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Sustainable Placemaking and Thermal Comfort Conditions in Urban Spaces: The Case Study of Avenida dos Aliados and Praça da Liberdade (Porto, Portugal) by Hélder Silva Lopes, Paula C. Remoaldo, Diogo Guedes Vidal, Vítor Ribeiro, Lígia Torres Silva, Javier Martín-Vide

“…The study identified solar exposure, wind patterns, and T_surf as the key determinants of thermal comfort. …”
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Bronchiolitis: A Real-Life Report of Increasing Compliance to Treatment Guidelines by Melodie O. Aricò, Francesco Accomando, Daniela Trotta, Anthea Mariani, Claudia Rossini, Claudio Cafagno, Letizia Lorusso, Enrico Valletta, Desiree Caselli, Maurizio Aricò

“…A comparative analysis of the treatment modalities used—high-flow nasal cannula (HFNC) oxygen therapy, inhaled medications, corticosteroids, and antibiotics—revealed a reduced use of non-recommended therapies (e.g., nebulized β2-agonists, steroids, and antibiotics) in Period 2, alongside heterogeneous patterns in HFNC use. Center-specific strategies, tailored to team dynamics and resource availability, effectively promoted greater adherence to evidence-based guidelines. …”
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Extraction and Spatiotemporal Analysis of Rubber Plantations on Hainan Island, China (1990–2023) Using Phenological and Multivariate Remote Sensing Features by Donghua Wang, Huichun Ye, Yanan You, Chaojia Nie, Jingjing Wang, Jingjuan Liao, Bingsun Wu, Lixia Shen, Dailiang Peng

“…The findings provide valuable scientific and technological support for the management of rubber production and the optimization of planting patterns on Hainan Island.…”
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Oat Cover Crop Integration in Alfalfa‐Tall Fescue Mixed Grasslands: Optimizing Sowing Ratios and Spatial Arrangements for Enhanced Productivity and Weed Suppression by Xiaoyu Zhao, Yuchen Sun, Yuan Li, Yu Jiao, Mengxin Xing, Jiayu Shi, Guofeng Yang, Chao Yang, Wei Tang, Yufang Xu, Juan Sun, Fuhong Miao

“…ABSTRACT The integration of cover crops during forage establishment represents a widely adopted agronomic strategy to suppress weed emergence, enhance stand establishment, and improve grassland community stability. …”
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Potential distribution and future shifts of invasive alien plants in China under climate change by Wenjing Ren, Jie Peng, Nawal Shrestha, Zhenghan Bian, Yingbo Yang, Jianquan Liu, Xiang Liu, Pan Huang, Jihua Wu

“…Understanding and predicting the distribution patterns of various invasive alien plants (IAPs) under future climatic conditions are essential to develop sustainable strategies for ecosystem and biodiversity conservation. …”
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Comparative effectiveness of maintenance doses of opioid agonist treatment among individuals with opioid use disorder: a target trial emulation protocol using a population-based ob... by M Eugenia Socías, Fahmida Homayra, Bohdan Nosyk, Jeong Eun Min, Julie Bruneau, Nikki Bozinoff, Shaun Seaman, P Todd Korthuis, Paxton Bach, Ehsan Karim, Michelle Zanette, Mary Clare Kennedy

“…Introduction Opioid agonist treatment (OAT) prescribing patterns have shifted in recent years in British Columbia (BC), Canada due to the increasingly toxic unregulated drug supply. …”
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Tick hazard in a Central European country: Mapping Europe’s principal tick-borne disease vector across Germany by Andrea Springer, Alexander Lindau, Katrin Fachet-Lehmann, Daniel Kämmer, Ingrid Bulling, Steffen Knoll, Nina Król, Dominik Fischer, Luisa Fischer, Marco Drehmann, Lidia Chitimia-Dobler, Madeleine Noll, Hannah Rose Vineer, Olaf Kahl, Martin Pfeffer, Christina Strube, Ute Mackenstedt

“…The ticks’ seasonal activity pattern was predominantly unimodal. The fact that the observed regional differences are contradictory to a previous estimation based on a combination of regional studies illustrates the need for an extensive and coordinated sampling effort to reliably estimate tick abundance at larger spatial scales. …”
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Trends in cancer incidence and mortality in the process of metropolitanization of Shanghai, 1973–2017 by Jiejie Qin, Jiejie Qin, Jiejie Qin, Jiejie Qin, Mengyin Wu, Shulin Zhao, Shulin Zhao, Shulin Zhao, Kai Gu, Renzhi Cai, Ziwei Tang, Defeng Zhu, Jingyan Tian, Jingyan Tian, Wei Yao, Baiyong Shen, Baiyong Shen, Baiyong Shen, Yan Shi

“…The most common cancer sites diagnosed were lung, colorectal, female breast, and male prostate in Shanghai in 2017, similar to the pattern in high-income countries. Stricter air control strategies, lower divorce rates, healthier lifestyles, and more effective HPV vaccination campaigns may be useful actionable measures of cancer prevention.ConclusionsThe longitudinal cancer data from the real world, which span decades, reported here and Shanghai’s experience in cancer prevention and control can be a reference for government guidelines in preventing population-level cancer incidence during city development.…”
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l-[5-11C]Glutamine PET imaging noninvasively tracks dynamic responses of glutaminolysis in non-alcoholic steatohepatitis by Yiding Zhang, Lin Xie, Masayuki Fujinaga, Yusuke Kurihara, Masanao Ogawa, Katsushi Kumata, Wakana Mori, Tomomi Kokufuta, Nobuki Nengaki, Hidekatsu Wakizaka, Rui Luo, Feng Wang, Kuan Hu, Ming-Rong Zhang

“…However, effective methods for assessing dynamic metabolic responses during interventions targeting glutaminolysis have not yet emerged. …”
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How Can We Make Scientific Events More Inclusive? Insights From Q&A Sessions and Surveys From an International Conference by Rebecca S. Chen, Tuba Rizvi, Ane Liv Berthelsen, Anneke J. Paijmans, Avery L. Maune, Barbara A. Caspers, Bernice Sepers, Isabel Damas‐Moreira, Isabel Schnülle, Jana Könker, Joseph I. Hoffman, Joelyn deLima, Jonas Tebbe, Kai‐Philipp Gladow, Lisa deVries, Marc Gilles, Nadine Schubert, Nayden Chakarov, Peter Korsten, Petroula Botsidou, Sabine Kraus, Stephen M. Salazar, Svenja Stöhr, Wolfgang Jockusch, Öncü Maraci

“…Self‐reports indicated that self‐identified women felt more comfortable asking questions when their own gender was represented (in the audience, by the speaker, and/or by the host) and when the setting was smaller. However, this pattern was not reflected in the observational data as perceived women asked fewer questions regardless of the situation. …”
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Anaesthetic profile of thymol and menthol in zebrafish larvae model by Raquel S.F. Vieira, Diana Sousa, Luís M. Félix, Carlos A.S. Venâncio

“…Both monoterpenes caused anaesthetic effects in a concentration-dependent manner, with concentrations of 200 mg/L exhibiting a similar profile to MS-222 and eugenol, as evidenced by the increased recovery times.Furthermore, anaesthesia with thymol and menthol caused post-anaesthesia motor pattern abnormalities, which supported some indicators of stress. …”
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Polarization Position Angle Swing and the Rotating Vector Model of Repeating Fast Radio Bursts by Xiaohui Liu, Heng Xu, Jiarui Niu, Yongkun Zhang, Jinchen Jiang, Dejiang Zhou, Jinlin Han, Weiwei Zhu, Kejia Lee, Di Li, Wei-Yang Wang, Bing Zhang, Xuelei Chen, Jia-Wei Luo, Rui Luo, Chenhui Niu, Yuanhong Qu, Bojun Wang, Fayin Wang, Pei Wang, Tiancong Wang, Qin Wu, Ziwei Wu, Jiangwei Xu, Yuan-Pei Yang, Jun-Shuo Zhang

“…Fast radio bursts (FRBs), typically highly polarized, usually have a nearly constant polarization position angle (PA) during each burst. Some bursts show significant PA variations, and one of them was claimed to have a PA variation pattern consistent with the prediction of the rotating vector model (RVM) commonly adopted to fit the PA variations in radio pulsars. …”
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Deciphering the secret codes in N7‐methylguanosine modification: Context‐dependent function of methyltransferase‐like 1 in human diseases by Huan Fang, Jing He, Dan Du, Xue Wang, Xinyu Xu, Linping Lu, Yefan Zhou, Yangyang Wen, Fucheng He, Yingxia Li, Hongtao Wen, Mingxia Zhou

“…Enormous knowledge gaps persist regarding context‐dependent regulatory networks of METTL1 and dynamic m7G modification patterns, necessitating mechanistic interrogation to bridge basic research with clinical translation in precision medicine.…”
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Characterization of Naegleria fowleri from two human cases: insights into its excretion/secretion products by Natalia Chacón Camacho, María Fernanda Steller Espinoza, Johan Alvarado-Ocampo, Antonio Osuna, Lissette Retana Moreira, Lissette Retana Moreira, Elizabeth Abrahams Sandí, Elizabeth Abrahams Sandí

“…Costa Rica reported the first three cases of PAM during 2020; from these, two N. fowleri isolates were recovered. …”
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Present and future interannual variability in wildfire occurrence: a large ensemble application to the United States by Theodore R. Keeping, Theodore R. Keeping, Boya Zhou, Wenjia Cai, Theodore G. Shepherd, I. Colin Prentice, I. Colin Prentice, Karin van der Wiel, Sandy P. Harrison, Sandy P. Harrison

“…The principal drivers of variability in simulated fire years are related either to interannual variability in fuel production or atmospheric moisture controls on fuel drying, but there are distinct geographic patterns in which each of these is the dominant control. …”
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Total and regional fat-to-muscle mass ratio and risks of pan-cancer: a prospective cohort study by Ruizhi Wang, Yudi Xu, Yuyuan Zhang, Yushuai Wu, Anning Zuo, Shutong Liu, Yuhao Ba, Hui Xu, Siyuan Weng, Zhaokai Zhou, Hongxuan Ma, Peng Luo, Quan Cheng, Xinwei Han, Zaoqu Liu

“…The analysis by combining BMI and FMR suggested potential interaction patterns, revealing some masked risks; for example, a significant increase in cancer incidence was also observed in individuals exhibiting high FMRs despite having low BMI. …”
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Genome-wide identification of the AcBAM family in kiwifruit (Actinidia chinensis cv. Hongyang) and the expression profiling analysis of AcBAMs reveal their role in starch metabolis... by Xuchen Gong, Mengfei Lin, Jie Song, Jipeng Mao, Dongliang Yao, Zhu Gao, Xiaoling Wang

“…Expression profiling showed that AcBAM5 and AcBAM13 were most highly expressed during postharvest storage and were strongly induced by ABA signal. …”
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