The Effect of Three-Dimensional Stabilization Thread Design on Biomechanical Fixation and Osseointegration in Type IV Bone by Nicholas J. Iglesias, Vasudev Vivekanand Nayak, Arthur Castellano, Lukasz Witek, Bruno Martins de Souza, Edmara T. P. Bergamo, Ricky Almada, Blaire V. Slavin, Estevam A. Bonfante, Paulo G. Coelho

“…Histological evaluation at 12 weeks revealed an increase in woven bone containing a greater presence of lacunae within the healing chambers in both groups, consistent with an intramembranous-like healing pattern and absence of bone dieback. The TP 3DS macrogeometry yielded a ~66% increase in average lateral load during pushout testing at baseline (T = 0 weeks, <i>p</i> = 0.036) and significantly higher bone-to-implant contact (BIC) values at 3 weeks post-implantation (<i>p</i> = 0.006), relative to the traditional TP implant. …”
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Single-cell profiling reveals a reduced epithelial defense system, decreased immune responses and the immune regulatory roles of different fibroblast subpopulations in chronic atro... by Lin Lin, Tingxuan Huang, Lizhi Li, Yang Lin, Feng Chen, Ziyi Zheng, Jie Zhou, Yizhe Wang, Weihao You, Yujie Duan, Yawen An, Shiwei He, Weimin Ye

“…C1Q + macrophages exhibited reduced phagocytosis, downregulated expression of pattern recognition receptors and decreased metabolic activity. …”
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FACTORS ASSOCIATED WITH ANXIETY AND DEPRESSION SPECTRUM DISORDERS IN BEHCHET’S DISEASE by P. S. Ovcharov, T. A. Lisitsyna, D. Yu. Veltishchev, O. F. Seravina, O. B. Kovalevskaya, S. I. Glukhova, Z. S. Alekberova, E. L. Nasonov

“…Sleep disorders, asthenic syndrome, and CI are significant in the pattern of ADSDs.…”
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Specific features of psychopathological manifestations in criminal clozapine intoxications by D. G. Slyundin, A. S. Livanov, V. V. Anuchin, A. G. Merkin, I. G. Bobrinskaya, E. V. Gutova

“…Clinical and laboratory studies were used to examine the patients. The pattern and situational features of the intoxication were revealed; the leading clinical syndrome and its degree were established. …”
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hnRNPA2B1 recognizes RNA virus SFTSV infection through mitochondrial DNA by Xin-bo Huang, Yue Zhang, Jing-wen Fan, Xin-yu Yu, Yun-lan Fang, Jin-xin Ren, Bin-yan Liu

“…However, it remains largely unclear whether A2B1 could function as a nucleic acid pattern-recognition receptor during cytoplasmic RNA virus infection. …”
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Spatiotemporal variations of vegetation and its response to climate change and human activities in loess hilly area of western Henan Province, China by Zhijia Gu, Zhijia Gu, Keke Ji, Keke Ji, Zixin Li, Gaohan Xu, Gaohan Xu, Ao Li, Yi Shen, Yi Shen, Chong Yao, Chong Yao, Boxiang Yang

“…The explanatory contributions of various interacting factors on NDVI showed a gradual increase trend.DiscussionThe NDVI changes in the loess hilly region of western Henan exhibit a "promotion-dominated, suppression-supplemented" anthropogenic influence pattern. Human activity intensity serves as the primary driving factor for vegetation changes in this area. …”
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The coesite–stishovite transition of hydrous, Al-bearing SiO₂: an in situ synchrotron X-ray study by M. Koch-Müller, C. Lathe, B. Wunder, O. Appelt, S. Bhat, A. Ebert, R. Farla, V. Roddatis, A. Schreiber, R. Wirth

“…Generally, the recovered samples of the in situ experiments contained less stishovite than expected from the last in situ XRD pattern before quenching. Thus, these investigations clearly show that hydrous, Al-rich stishovite that formed at high pressure (<span class="inline-formula"><i>P</i></span>) and temperature (<span class="inline-formula"><i>T</i></span>) could, at least partly, not be quenched to room conditions and transformed to coesite with unusually high (Al, H) contents. …”
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Preparation and characterization of marker graphite tiles for PWI research of HL-3 by Jingyang Han, Yaxiong He, Dongye Zhao, Laizhong Cai, Yiqin Wang, Wei Qian, Wenyu Huang, Yong Lu, Lijun Cai, Wulyu Zhong

“…In tokamaks, to understand the erosion and deposition pattern of plasma facing components (PFCs) is crucial for the study of plasma wall interaction (PWI). …”
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Progress on Physiological Mechanisms of Rice Spikelet Degeneration at Different Panicle Positions Caused by Abiotic Stress by Wang Jingqing, Wang Yaliang, Chen Yulin, Chen Huizhe, Xiang Jing, Zhang Yikai, Wang Zhigang, Zhang Yuping

“…Sucrose serves as the main carbohydrate source for spikelet development, demonstrating an apical dominance pattern that favors spikelet formation. However, under abiotic stress, the inhibition of sucrose decomposition, rather than sucrose transport impairment, predominantly contributes to aggravated spikelet degeneration at the basal panicle positions. …”
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Dichotomous intronic polyadenylation profiles reveal multifaceted gene functions in the pan-cancer transcriptome by Jiao Sun, Jin-Young Kim, Semo Jun, Meeyeon Park, Ebbing de Jong, Jae-Woong Chang, Sze Cheng, Deliang Fan, Yue Chen, Timothy J. Griffin, Jung-Hee Lee, Ho Jin You, Wei Zhang, Jeongsik Yong

“…The application of this workflow to RNA-seq data from The Cancer Genome Atlas demonstrated that this dichotomous intronic APA pattern is a consistent feature in transcriptomes across both normal tissues and various cancer types. …”
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Influencing factors for treatment escalation from metformin monotherapy in youth-onset type 2 diabetes in Northern Taiwan by Yi-Hsuan Chou, Ya-Ting Su, Fu-Sung Lo, Chiao-Fan Chiu, Yen-Chun Huang

“…This retrospective cohort study endeavors to scrutinize and assess the pattern of treatment modification and associate factors among 79 young people with T2D in Taiwan.The study categorized participants into three distinct groups based on their treatment trajectory and outcomes: (1) those maintaining metformin (n = 34); (2) cases achieving remission (n = 7); and (3) individuals experiencing escalation through oral drugs or insulin (n = 38). …”
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The AcrAB efflux pump contributes to the virulence of Enteroaggregative E. coli by influencing the aggregative behavior by Martina Laudazzi, Emily Schifano, Francesca Sivori, Ludovica Altieri, Daniela Uccelletti, Enea G. Di Domenico, Bianca Colonna, Martina Pasqua, Gianni Prosseda

“…The characteristic aggregative pattern of EAEC is also strongly impaired in the absence of AcrB or in the presence of an efflux-defective AcrB D408A transporter, while it is restored in the ΔacrB strain complemented with acrB. …”
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Title not available by Debat, Vincent, López-Villavicencio, Manuela, Llaurens, Violaine

“…Such learning favours the locally abundant colour pattern and promotes the local convergence in sympatric species. …”
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Mapping Technologies for Catheter Ablation of Atrial Fibrillation Beyond Pulmonary Vein Isolation by Giulio La Rosa, Jorge G Quintanilla, Ricardo Salgado, Juan José González-Ferrer, Victoria Cañadas-Godoy, Julián Pérez-Villacastín, Nicasio Pérez-Castellano, José Jalife, David Filgueiras-Rama

“…These novel tools – although mainly limited to research series – represent a significant step forward towards the understanding of complex patterns of propagation during AF and the potential achievement of patient-tailored AF ablation strategies for the near future.…”
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Cisd2 delays atrial aging via a modulation of calcium homeostasis that mitigates atrial myopathy by Chi-Hsiao Yeh, Zhao-Qing Shen, Li-Hsien Chen, Carol Seah, Tsai-Yu Tzeng, Chien-Yi Tung, Wen-Tai Chiu, Cheng-Heng Kao, Ting-Fen Tsai

“…Finally, transcriptomic analysis reveals that Cisd2 protects the atrium from metabolic reprogramming and preserves into old age a transcriptomic profile resembling a youthful pattern, thereby safeguarding the atrium from age-related injury. …”
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Interspecies Differences in Cytomegalovirus Inhibition by Cardiac Glycosides—A Unique Role of the Alpha3 Isoform of the Na⁺/K⁺-ATPase Pump by Hong Mei, Hongyi Cai, Fengjie Liu, Rajkumar Venkatadri, Halli E. Miller, Angela J. Mathison, Hua-Yu Leo Wang, Simone C. Silva, George A. O’Doherty, Ravit Arav-Boger

“…The α subunit of the Na⁺/K⁺-ATPase pump has four isoforms (α1–4), each with unique tissue distribution and expression pattern; their contributions to antiviral activities have not been studied. …”
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Dam‐Induced Alternations of Flow and Sediment Regimes in the Tibetan Plateau: An Example of the Yarlung Tsangpo River by Dongmei Zhao, Kunlong He, Donghong Xiong, Xixi Lu, Xiaomin Qin, Xiaodan Wang, Wenduo Zhang

“…Large flood events with high‐magnitude sediment were almost absent, and a figure‐eight hysteresis pattern indicated weakened sediment transport. These findings underscore the need for incorporating time‐varying hydrological dynamics into dam operation strategies to minimize negative impacts on sediment transport and aquatic ecosystems, providing essential insights for sustainable water resource management and future hydropower planning in alpine river basins.…”
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Impact of filgotinib on pain control in the phase 3 FINCH studies by Bruno Fautrel, Peter Nash, Arthur Kavanaugh, Peter C Taylor, René Westhovens, Rieke Alten, Janet Pope, Dick de Vries, Chris Watson, Georg Pongratz, Pieter-Jan Stiers, Ken Hasegawa, Shangbang Rao

“…In FINCH 1, at week 24, 35.8%, 25.0%, 24.6% and 11.6% of patients in the filgotinib 200 mg, filgotinib 100 mg, adalimumab and placebo arms (each plus methotrexate) achieved VAS pain ≤20 mm in addition to DAS28-CRP remission; 26.3%, 17.9%, 17.2% and 7.6% achieved VAS pain ≤10 mm in addition to DAS28-CRP remission. A similar pattern was seen for CDAI remission. Time during which VAS pain was ≤10 or ≤20 mm was longest with filgotinib 200 mg and comparable between adalimumab and filgotinib 100 mg. …”
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hMPV Outbreaks: Worldwide Implications of a Re-Emerging Respiratory Pathogen by Alexandra Lianou, Andreas G. Tsantes, Petros Ioannou, Efstathia-Danai Bikouli, Anastasia Batsiou, Aggeliki Kokkinou, Kostantina A. Tsante, Dionysios Tsilidis, Maria Lampridou, Nicoletta Iacovidou, Rozeta Sokou

“…Since its initial identification in 2001, hMPV has been recognized globally for its seasonal circulation pattern, predominantly in late winter and spring. hMPV is a leading etiological agent, accounting for approximately 5% to 10% of hospitalizations among pediatric patients with acute respiratory tract infections. hMPV infection can result in severe bronchiolitis and pneumonia, particularly in young children, with clinical manifestations often indistinguishable from those caused by human RSV. …”
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Spatiotemporal distribution and reproductive biology of the brown croaker (Miichthys miiuy) in the southwestern waters of Korea by Seong Yong Moon, Gun Wook Baeck, Jin Ho Jung, Haeyoung Choi, Changsin Kim, Myung Sung Koo, Jeong-Ho Park

“…Additionally, total length at sexual maturity at 50%, 75%, and 97.5%, as well as the sex ratio, were determined.ResultsM. miiuy, captured using offshore gillnets and stow nets, exhibited a seasonal migration pattern: a winter presence near Jeju Island, followed by a northward movement in spring, a summer shift to the shallow waters of Shinan, and an autumnal migration to the waters around Jeju Island for overwintering. …”
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