Early Dynamics of Circulating Tumor DNA Following Curative Hypofractionated Radiotherapy Related to Disease Control in Lung Cancer by Kyungmi Yang, Jae Myoung Noh, Yeon Jeong Kim, Hongryull Pyo

“…<b>Background/objectives:</b> We aimed to characterize the dynamic pattern of circulating tumor DNA (ctDNA) during hypofractionated radiation therapy (RT) in patients with lung cancer and assess its clinical relevance. …”
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Mitigating retail rice price volatility for sustainable supply chains: an optimization and regression-based approach [version 2; peer review: 2 approved] by Arif Shafwan Rasyid, Lucia Diawati

“…The explanatory variable is forecasted using methods best suited to its historical pattern. Results The model was tested using data from 2020 to 2023. …”
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A multicentre, prospective cohort study comparing two endoscopic procedures for the treatment of gastric muscularis propria lesions by Zhaohui Liu, Xiangyu Wang, Genhua Yang, Jiefeng Li, Yongsheng Lu, Dayong Sun, Ruinuan Wu

“…There were no differences in age, gender, location, tumour size, growth pattern, resection time, histology diagnosis, or follow-up time (P > 0.05). …”
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Physiological insights into the responses of tea plants to aluminum through an integrated transcriptomic and metabolomic analysis by Xinwan Zhang, Shijie Luo, Xiali Ye, Lin Liu, Xinxin Jia, Deyuan Jiang, Weiwei Wen

“…Compared to 0 mM Al treatment, low Al concentrations (0.4 mM) enhanced root vitality by 8.91%, while higher Al concentrations (10 and 100 mM) reduced root vigor by 19.31% and 76.81%, respectively. In a similar pattern, the electron transfer rate in leaves remained stable under low Al levels but significantly decreased under high Al conditions. …”
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Malignant peripheral nerve sheath tumour of the oesophagus: a case report by Kento Tomizawa, Tatsuya Miyazaki, Arisa Yamaguchi, Ryoya Honda, Marie Hoshino, Mitsuhiro Yanai, Yohei Miyamae, Ryo Kurosaki, Hisashi Shimizu, Kazuhisa Arakawa, Munenori Ide

“…Some regions showed nuclear polymorphism or a storiform pattern, and locally, there were approximately 7 mitoses/10 HPFs. …”
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Metabolic Abnormalities in a Cohort of Overweight and Obese Children in an Urban Setting of Sri Lanka by Loretta S. Warnakulasuriya, Dulani L. Samaranayake, Adikaram V. N. Adikaram, Manel M. A. Fernando, Elisabet Rytter, Iris Ciba, Peter Bergsten, Anders H. Forslund, K. D. Renuka Ruchira Silva, Vithanage Pujitha Wickramasinghe

“…Anthropometry, fat mass (FM), and blood pressure were measured. Hepatic fat pattern was assessed ultrasonically. The data of 403 children (210 boys) were analysed. …”
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Clinical characteristics and factors associated with recurrence and long-term prognosis in patients with MOGAD by Wenlin Sun, Yinyin Xie, Aoya Han, Xinru Zhou, Shijie Zhang, Yi Xie, Nanchang Xie

“…A higher EDSS score at discharge (OR: 5.05, 95% CI: 1.27–20.07, p = 0.021)and more previous episodes (OR: 9.24, 95% CI: 1.35–63.10, p = 0.023), were associated with a poor long-term prognosis; whereas steroid therapy for &gt;5 weeks at first diagnosis (OR: 0.001, 95% CI: 0.00–0.33, p = 0.019) and type I isoelectric focusing pattern (OR: 0.004, 95% CI: 0.00–0.402, p = 0.043) were associated with favorable long-term prognosis.ConclusionAfter the first episode, steroid maintenance for an appropriate period following discharge is important for achieving a favorable long-term prognosis, particularly in patients with a high EDSS score at discharge and those at a heightened risk of recurrence.…”
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The Importance of Physiochemical Processes in Decarbonisation Technology Applications Utilizing the Subsurface: A Review by Ieva Kaminskaite, Sandra Piazolo, Andy R. Emery, Nicholas Shaw, Quentin J. Fisher

“…Most importantly, the biggest uncertainties emerge in prediction of fracture pattern development and understanding the extent and timescales of chemical reactions that occur within the decarbonising applications where external fluid or gas is cyclically injected and invariably causes disequilibrium within the system. …”
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Distinct ionospheric long-term trends in Antarctica due to the Weddell Sea Anomaly by M. Canales, T. Duran, M. Bravo, A. Zalizovski, A. Zalizovski, A. Zalizovski, A. Foppiano

“…In contrast, Syowa and Mawson show different trends, with Syowa not having a clear trend pattern, and Mawson showing negative trends throughout the year. …”
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Cardiac fibroblasts regulate myocardium and coronary vasculature development in the murine heart via the collagen signaling pathway by Yiting Deng, Yuanhang He, Juan Xu, Haoting He, Manling Zhang, Guang Li

“…This approach enabled us to discern the anatomical pattern of cardiac FBs and identify approximately one EC and four CMs directly interacting with each FB. …”
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The RNA-binding protein Puf5 and the HMGB protein Ixr1 regulate cell cycle-specific expression of CLB1 and CLB2 in Saccharomyces cerevisiae. by Megumi Sato, Varsha Rana, Yasuyuki Suda, Tomoaki Mizuno, Kenji Irie

“…However, considering that CLB1 and CLB2 reportedly undergo a similar expression pattern during the cell cycle, we re-examined CLB2 expression in the puf5Δ mutant in cell cycle-synchronized cultures and found that CLB2 expression was decreased in the puf5Δ mutant strain. …”
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Hydrocarbon forming condition and accumulation model of the buried-hill reservoir in the Beier sag, Hailar Basin by Yixuan Ran

“…The forming condition and pattern are different from each other, which is the main reason for the variation distribution of inside bedrock oil reservoir and weathering crust oil reservoir.…”
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Integrative Analysis of Neutrophil-Associated Genes Reveals Prognostic Significance and Immune Microenvironment Modulation in Cervical Cancer by Ting Hu, Haijing Wu, Xinghan Cheng, Haoyue Gao, Min Yang

“…The model’s association with the tumor immune microenvironment and immunotherapy response was further analyzed. The expression pattern of SEMA6B was explored using cell lines, clinical subgroups, and human protein profiles, and its immunological relevance was evaluated using multiple immune infiltration algorithms. …”
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Microsatellite instability as a reliable marker of coexisting endometrial cancer in atypical endometrial hyperplasia by А. E. Protasova, G. A. Raskin, M. S. Sobivchak

“…The detection of MSI in a histological sample is more often associated with the presence of EC, while the loss of the PMS2 and/or MLH1 genes increases the likelihood of a cancer diagnosis. If during additional immunohistochemical analysis a loss of these genes is observed, then EC can be diagnosed, even with an ambiguous histological pattern.Conclusion. …”
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Accelerometer-measured physical activity, frailty, and all-cause mortality and life expectancy among middle-aged and older adults: a UK Biobank longitudinal study by Yang Yang, Liangkai Chen, Filippos T. Filippidis

“…Notably, across the frailty spectrum, individuals in the low tertile of TVPA, MVPA, and LPA, or the top tertile of ST, were associated with reduced life expectancy, with this pattern being more pronounced among frail men compared to frail women. …”
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A Trust Based Anomaly Detection Scheme Using a Hybrid Deep Learning Model for IoT Routing Attacks Mitigation by Khatereh Ahmadi, Reza Javidan

“…According to the presented results, the implemented detection scheme on all attack scenarios, demonstrated that the trend of estimated anomaly between real and predicted routing behavior is similar to the evaluated attack frequency of malicious nodes during the RPL process and in contrast, analyzed trust scores represent an opposite pattern, which shows high accurate and timely detection of attack incidences using our proposed trust scheme.…”
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Fluid–solid coupling productivity analysis of multi-stage fractured horizontal wells in shale reservoirs by Qian QI, Ming YUE, Weiyao ZHU, Wenjiang MA

“…The simulation results of the model align with actual field data, showing that gas production follows an “L-shaped” decline pattern with a coincidence rate exceeding 70%, verifying the model’s accuracy.…”
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Reproductive changes among women in their 40s: A cross‐sectional study by Ingela Lindh, Finn Egil Skjeldestad, Oskari Heikinheimo, Helena Hognert, Øjvind Lidegaard, Christina Bergh, Kristina Gemzell‐Danielsson

“…Abstract Introduction The aim was to describe and compare changes in the reproductive pattern of women in their 40s observed over a decade in Scandinavia. …”
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Feasibility of real-time in vivo 89Zr-DFO-labeled CAR T-cell trafficking using PET imaging. by Suk Hyun Lee, Hyunsu Soh, Jin Hwa Chung, Eun Hye Cho, Sang Ju Lee, Ji-Min Ju, Joong Hyuk Sheen, Hyori Kim, Seung Jun Oh, Sang-Jin Lee, Junho Chung, Kyungho Choi, Seog-Young Kim, Jin-Sook Ryu

“…No significant accumulation of labeled cells was identified in tumors. A similar pattern was observed in ex vivo biodistributions on day 7 (lung 3.0% ± 1.0%ID, liver 19.8% ± 2.2%ID, spleen 2.3% ± 1.7%ID). 89Zr-DFO-labeled hPBMC/CAR T-cells showed a similar distribution, compared with Jurkat/CAR T-cells, on serial PET images. …”
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Complex Responses to Climate Warming of Arctic‐Alpine Plant Populations From Different Geographic Provenance by Lisa Brancaleoni, Renato Gerdol, Andrea Mondoni, Simone Orsenigo, Lisa Scramoncin, Carla Lambertini, Chiara Cianferoni, Thomas Abeli

“…The plants of all populations performed overall well, in terms of growth rate and ecophysiology, under the heat spell, with the plants of the Swedish population exhibiting the highest phenotypic plasticity. Such a pattern was associated with the highest genetic variation in the Swedish population. …”
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