SETDB1 knockdown boosts recombinant protein in CHO cells via epigenetic transcriptional silencing by Jiang-Tao Lu, Miao Zhang, Yan-Ping Gao, Lu-Lu Yang, Zhao-Ming Cui, Ming-Ming Han, Xi Zhang, Hong-Yan Xu, Xiao-Yin Wang, Le-Le Qiu, Zi-Chun Hua, Tian-Yun Wang, Yan-Long Jia

“…Transcriptome dynamics analysis revealed that SETDB1 silencing induces transcriptional pattern remodeling in transfected cells. These findings elucidate SETDB1's regulatory role in CHO cells and provide actionable insights for the optimisation of recombinant protein production through cell engineering strategies.…”
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Rural Development and Food Security Through Homestead Vegetable Production: A Case Study by Kanij Fatema Tuz Zohora, Bir Jahangir Shirazy, Md. Asaduzzaman, Nadia Akter, Saikat Hossain Bhuiyan, A. K. M. Ariful Hoque, A. A. M. Mohammad Mustakim, Md. Maniruzzaman, A. B. M. Zahidul Hoque, Abul Kalam Azad

“…Cumilla Sadar Dakshin region is highly diverse in respect to land types, topography, agro-ecology, land-use pattern, cropping systems and crop variability & variety. …”
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Impact of Irrigation on Soil Water Balance and Salinity at the Boundaries of Cropland, Wasteland and Fishponds under a Cropland–Wasteland–Fishpond System by Cuicui Yu, Haibin Shi, Qingfeng Miao, José Manuel Gonçalves, Xu Dou, Zhiyuan Hu, Cong Hou, Yi Zhao, Hua Zhang

“…In order to explore the effect of fishponds on soil water, salt transport and salinization in cropland wasteland, a study on soil water balance and salt distribution pattern in a cropland–wasteland–fishpond system was carried out in 2022–2023 in a typical study area selected from the Yichang Irrigation Area of the Hetao Irrigation District. …”
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Expression of RNautophagy/DNautophagy-related genes is regulated under control of an innate immune receptor by Yuuki Fujiwara, Kazuki Oroku, Yinping Zhou, Masayuki Takahashi, Taiichi Katayama, Keiji Wada, Nobuyuki Tsutsumi, Tetsuo Sato, Tomohiro Kabuta

“…Double-stranded RNA (dsRNA) is a molecular pattern uniquely produced in cells infected with various viruses as a product or byproduct of replication. …”
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Facile synthesis of nano-Si/graphite composites from rice husk for high performance lithium-ion battery anodes by Crystina Simanjuntak, Sabarmin Perangin-angin, Amru Daulay, Suci Aisyah Amaturrahim, Indah Revita Saragi, Dilshad Hussain, Arwadi Sinuraya

“…The results of XRD showed that nano-Si shows 2θ at 28°, 47°, 56°, 69°, and 76° is the diffraction pattern of silica and carbon, respectively. XPS spectrum at nano-Si showed a spectrum at a binding energy of 97.6 eV and 101.2 eV, indicating Si–Si and Si–OH. …”
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Interactive Effects of Ambient Ozone and Meteorological Factors on Cerebral Infarction: A Five-Year Time-Series Study by Yanzhe Chen, Songtai Yang, Hanya Que, Jiamin Liu, Zhe Wang, Na Wang, Yunkun Qin, Meng Li, Fang Zhou

“…<b>Results</b>: O₃ exposure was significantly associated with increased cerebral infarction risk, particularly during the warm season. A bimodal temperature-lag pattern was observed, as follows: moderate temperatures (10–20 °C) were associated with immediate effects, while cold (<10 °C) and hot (>30 °C) temperatures were linked to delayed risks. …”
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Parallel Changes in Harvey-Bradshaw Index, TNFα, and Intestinal Fatty Acid Binding Protein in Response to Infliximab in Crohn’s Disease by Anas Kh. Al-Saffar, Carl Hampus Meijer, Venkata Ram Gannavarapu, Gustav Hall, Yichen Li, Hetzel O. Diaz Tartera, Mikael Lördal, Tryggve Ljung, Per M. Hellström, Dominic-Luc Webb

“…Combining all 30 infusion/follow-up pairs also revealed changes in I-FABP. HBI followed this pattern; CRP declined gradually. I-FABP was expressed in epithelium of stomach, jejunum, ileum, and colon, with the highest expression in jejunum and ileum. …”
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The Effects of Targeted Temperature Management on Oxygen-Glucose Deprivation/Reperfusion-Induced Injury and DAMP Release in Murine Primary Cardiomyocytes by Giang Tong, Phuong D. Lam, Franka Brey, Jana Krech, Sylvia J. Wowro, Nalina N. A. von Garlen, Felix Berger, Katharina R. L. Schmitt

“…Ischemia/Reperfusion (I/R) is a primary cause of myocardial injury after acute myocardial infarction resulting in the release of damage-associated molecular patterns (DAMPs), which can induce a sterile inflammatory response in the myocardial penumbra. …”
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Trade-offs among yield, water productivity, water footprint, and economic benefits for wheat production under conservation tillage: A long-term field experiment approach by Linlin Wang, Lingling Li, Junhong Xie, Zhuzhu Luo, Setor Kwami Fudjoe, Jairo A. Palta, Shiqing Li

“…Additionally, NTS reduced the water consumption during the early stage but increased the water utilization from heading to harvest, while TP, and NTP exhibited the opposite pattern. …”
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Motor learning leverages coordinated low-frequency cortico-basal ganglia activity to optimize motor preparation in humans with Parkinson’s disease by Kara N. Presbrey, Kara N. Presbrey, Kara N. Presbrey, Thomas A. Wozny, Thomas A. Wozny, Kenneth H. Louie, Kenneth H. Louie, Simon Little, Simon Little, Philip A. Starr, Philip A. Starr, Reza Abbasi-Asl, Reza Abbasi-Asl, Doris D. Wang, Doris D. Wang

“…More generally, coordinated network δ supported a complex pattern of learning-driven cross-frequency couplings within and between cortex and basal ganglia, including striatal lead of cortical beta (β, 12–30 Hz) activity, reflecting the specialized roles of these brain regions in motor preparation. …”
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Severe tremors induced by tiletamine e-cigarette and alcohol use: a case report by Bojie Zhou, Bojie Zhou, Shanghao Yang, Shanghao Yang, Xiafeng Zhou, Xiafeng Zhou, Qian Chen, Qian Chen, Ewen Tu, Ewen Tu, Bo Zhang, Bo Zhang, Li Shi, Li Shi, Xuhui Zhou, Xuhui Zhou

“…Based on his substance use pattern and related outcomes, he was diagnosed with phencyclidine use disorder. …”
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Effector Pt31812 from Puccinia triticina acts as avirulence factor for Lr42-mediated resistance in wheat by Jianyuan Li, Jianyuan Li, Jiali Li, Jie Wei, Jie Wei, Lin Li, Yue Qi, Yue Qi, Yue Zhang, Yue Zhang, Wenxiang Yang, Qian-Hua Shen

“…In the study, Pt31812 was cloned by PCR, and the expression pattern and structure were analyzed by qRT-PCR and online softwares. …”
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PRODEM: an annual series of summer DEMs (2019 through 2022) of the marginal areas of the Greenland Ice Sheet by M. Winstrup, H. Ranndal, S. Hillerup Larsen, S. B. Simonsen, K. D. Mankoff, K. D. Mankoff, K. D. Mankoff, R. S. Fausto, L. Sandberg Sørensen

“…We observe a general lowering of surface elevations during the 4-year PRODEM period, but the spatial pattern of change is highly complex and with annual changes superimposed. …”
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Exploring the Hemp Virome and Assessing Hemp Germplasm for Resistance to an Emerging Pathogen by Laine Hackenberg, Jinlong Han, Jacob MacWilliams, Marylee L. Kapuscinski, Mark Stenglein, Rich Fletcher, Punya Nachappa

“…High-throughput sequencing revealed a total of seven viruses across both years from 48 pooled samples: alfalfa mosaic virus, beet curly top virus (BCTV), cannabis cryptic virus, cannabis sativa mitovirus 1, grapevine line pattern virus, opuntia umbra-like virus, and tomato bushy stunt virus. …”
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Association of serum surfactant protein D and SFTPD gene variants with asthma in Danish children, adolescents, and young adults by Benjamin Hoffmann‐Petersen, Raymond Suffolk, Jens J. H. Petersen, Thomas H. Petersen, Charlotte Brasch‐Andersen, Arne Høst, Susanne Halken, Grith L. Sorensen, Lone Agertoft

“…Abstract Background Surfactant Protein D (SP‐D) is a pattern recognition molecule belonging to the family of collectins expressed in multiple human organ systems, including the lungs. …”
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Time sequence of bacterial and fungal pathogens causing infections in trauma patients by Joost D J Plate, Falco Hietbrink, Karlijn J P van Wessem, Leo Koenderman, Emma J de Fraiture, Frederique J C van Eerten, Miquel B Ekkelenkamp, Loulou V Duebel, Nienke Vrisekoop

“…Purpose A time sequence occurs in pathogens leading to infections in Intensive Care Unit (ICU) patients with a compromised immune system. A similar pattern may also occur in (multi)trauma patients characterized by similar impaired immunological responses. …”
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Non-targeted screening of organic micropollutants in drinking water: Evidence of contamination from purification systems and plastic materials by Kailin Shen, Daeho Kang, Heewon Jang, Junho Jeon

“…A total of 41 MPs were tentatively identified through MS/MS spectral pattern diagnosis, including plasticizers, plastic derivatives, organophosphorus flame retardants (OPFRs), pesticides, and pharmaceuticals. …”
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Disease activity trajectories from childhood to adulthood in the population-based Nordic juvenile idiopathic arthritis cohort by Kristiina Aalto, Anders Fasth, Troels Herlin, Marite Rygg, Ellen Berit Nordal, LILLEMOR BERNTSON, Mia Glerup, Veronika Rypdal, Martin Rypdal, Ellen Arnstad, Charlotte Myrup, Suvi Peltoniemi

“…The increase in the PaGA was significantly higher than the increases in the PhGA and the active joint count (p&lt;0.0001). A similar pattern was found among all the patients with active disease in the total cohort. …”
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Influence of Environmental Conditions Associated with Low and High Altitudes on Economic and Quality Characteristics of Fruit Ripening of <i>Camellia chekiangoleosa</i> Hu by Teng Wei, Shengyue Zhong, Bin Huang, Kang Zha, Jing Li, Qiang Wen

“…Our investigations showed that altitude has no influence on the growth pattern of <i>C. chekiangoleosa</i> fruit shells and seed oils, and the differences in samples between different altitudes gradually decreased with the ripening of <i>C. chekiangoleosa</i>. …”
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Emission inventory development for spatiotemporal release of vanadium from anthropogenic sources in China by H. Zhang, H. Zhang, B. Zhang, B. Jiang, Q. Li, X. Hu, Y. Xing

“…Coal combustion (46.7 %) and stationary oil burning (40.1 %) are the largest vanadium contributors. The emission pattern is mainly shaped by regional activity levels, with Shandong, Liaoning, Hebei, and Guangdong contributing 35.8 % of national inventories. …”
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