Differential susceptibility and role for senescence in CART cells based on costimulatory domains by Ismail Can, Elizabeth L. Siegler, Olivia L. Sirpilla, Claudia Manriquez-Roman, Kun Yun, Carli M. Stewart, Jennifer M. Feigin, Makena L. Rodriguez, Omar L. Gutierrez-Ruiz, Ekene J. Ogbodo, Truc N. Huynh, Brooke L. Kimball, Long K. Mai, Mehrdad Hefazi, Lionel Kankeu Fonkoua, Hong Xia, Imene Hamaidi, Berke Alkan, Fatih Sezer, H. Atakan Ekiz, R. Leo Sakemura, Saad S. Kenderian

“…Using CD19-targeted CART cells with costimulation via 4-1BB-CD3ζ (BBζ) or CD28-CD3ζ (28ζ), we showed that CART cells undergo functional, phenotypical, and transcriptomic changes of senescence, which is more prominent in BBζ. …”
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Dynamic in-situ reconstruction of active site circulators for photo-Fenton-like reactions by Chang-Wei Bai, Fu-Qiao Yang, Pi-Jun Duan, Zhi-Quan Zhang, Yi-Jiao Sun, Xin-Jia Chen, Fei Chen, Han-Qing Yu

“…The mechanism underlying the in-situ reconstruction of active sites for periodate functionalization was elucidated through theoretical calculations, coupled with semi-in-situ X-ray photoelectron spectroscopy (XPS) and electrochemical analyses. …”
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Peculiarities of perioperative intensive therapy in patients with an acute calculous cholecystitis by A. I. Denysenko, V. I. Cherniy

“…The first one have consisted of 63 patients, in whom intensive therapy, directed on support of vital functions, was conducted, while in a second group (68 patients) the data of indirect calorimetry were used additionally. …”
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Poly(butylene adipate-co-terephthalate) (PBAT)/AgFe2O4 biopolymer nanocomposite-based flexible triboelectric nanogenerator as a self-powered touch sensor by Vishnu Kadabahalli Thammannagowda, Kariyappa Gowda Guddenahalli Shivanna, Smitha Ankanahalli Shankaregowda, Stéphane Panier, Prashantha Kalappa

“…This study presents a simple, durable, low-cost, and biodegradable poly(butylene adipate-co-terephthalate)/AgFe2O4 (PBAT/AFO) based TENG, utilizing an innovative approach towards environmental sustainability. …”
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Portugal’s Wattle and Daub Constructive Legacy by Kátia Soares, Isabel Torres, Ana Velosa

“…This involves an in-depth study of traditional heritage, aiming for durable, sustainable, and economically viable repair solutions. …”
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Fabrication and characterization of carbon and glass fiber reinforced thermoplastic composites by fused filament fabrication by Dilşad Akgümüş Gök, Berk Dinçer Akay

“…However, the mechanical limitations of thermoplastic materials limit their use in broader functional applications. In this study, PLA and ABS thermoplastics were reinforced with 1%, 3%, and 5% carbon fiber (CF) and glass fiber (GF) to improve their mechanical performance. …”
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Magnitude of antigen-specific T-cell immunity the month after completing vaccination series predicts the development of long-term persistence of antitumor immune response by Mary L Disis, John B Liao, Jessica L Reichow, Lupe G Salazar, Sasha E Stanton, Katie M Hitchcock-Bernhardt, James Y Dai, Jong-Baeck Lim, Theodore A Gooley

“…The magnitude and differentiation of effective, durable immune responses depend on antigen-specific precursor frequencies. …”
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IL-7 armed binary CAR T cell strategy to augment potency against solid tumors by Alejandro G. Torres Chavez, Mary K. McKenna, Anmol Gupta, Neha Daga, Juan Vera, Ann M. Leen, Pradip Bajgain

“…MethodsIn this study we explore a dual antigen targeting strategy by directing independent CARs against the solid tumor targets PSCA and MUC1. To enhance functional persistence in a tumor-localized manner, we expressed the transgenic IL-7 cytokine and receptor (IL-7Rα) in respective CAR products. …”
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Harnessing novel genetic markers for scald resistance from gene bank spring barley genotypes by Su Myat Noe, Johanna Åstrand, Mustafa Zakieh, Pawan Kumar Singh, Eva Johansson, Aakash Chawade

“…Identifying and utilizing scald resistance genes and quantitative trait loci (QTL) to develop barley cultivars with durable and effective resistance to scald is crucial. …”
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Innovative 3D printing technologies and advanced materials revolutionizing orthopedic surgery: current applications and future directions by Bo Cong, Bo Cong, Haiguang Zhang, Haiguang Zhang

“…Looking ahead, innovations in smart materials and functionally graded materials (FGMs), along with advancements in bioprinting, hold promise for overcoming these obstacles and expanding the capabilities of 3D printing in orthopedics. …”
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Sol–Gel Thin Films for the Protection of Ancient Glass Artifacts: A Performance Comparison Between Inorganic and Hybrid Silica Compositions by Stefano Centenaro, Elti Cattaruzza, Antonella Glisenti, Leonardo Puppulin, Giulia Franceschin, Arianna Traviglia

“…This research highlights the potential of hybrid sol–gel coatings as effective and durable protective solutions for glass conservation.…”
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Passive radiative thermal management using phase-change metasurfaces by Leena Singh, Erbin Qiu, Andrew E Cardin, Aiping Chen, Ting S Luk, Jon A Schuller, Diego A R Dalvit, Ivan K Schuller, Wilton J M Kort-Kamp, Abul K Azad

“…Therefore, the proposed durable and eco-friendly metasurface will be an excellent candidate for essential passive thermal regulation systems across residential and terrestrial applications.…”
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Irreversible electroporation synergizes with oncolytic virus enhances the infiltration of cytotoxic T lymphocytes in the tumor immune microenvironment: a leap from focal therapy to... by Shaogang Wang, Zhi-Yu Xia, Jia-Cheng Xiang, Jin-Zhou Xu, Jian-Xuan Sun, Qi-Dong Xia

“…By bridging focal ablation with adaptive immunity, the synergistic effect—IRE for systemic CTL priming and OVs for localized immune amplification—transforms residual tumors into immunogenic niches, counteracting post-IRE recurrence through durable CTL-mediated clearance. The strategy leverages IRE’s functional preservation and OVs’ targeted lytic activity to synergistically enhance therapeutic efficacy while minimizing invasiveness.…”
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Epstein-Barr virus mRNA vaccine synergizes with NK cells to enhance nasopharyngeal carcinoma eradication in humanized mice by Kun Huang, Xiao-jun Lin, Jing-chu Hu, Ting-ying Xia, Feng-ping Xu, Jian-dong Huang, Nan Zhou

“…Combined administration of mRNA vaccine and NK cells synergistically improved therapeutic efficacy by durably suppressing or eradicating NPC tumors in humanized mice. …”
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A comprehensive review of diffuse reflectance infrared Fourier transform spectroscopy (DRIFTS) techniques in protonic ceramic cells (PCCs): Current status and future perspective by Zixian Wang, Fan Liu, Yuqing Meng, Wenjuan Bian, Haiyan Zhao, Chuancheng Duan, Michael T. Benson, Meng Li, Bin Liu, Dong Ding

“…Ultimately, this review underscores the critical role of DRIFTS in accelerating the development of high-performance and durable PCCs for next-generation energy solutions, offering methodologies and insights broadly applicable to a wide range of electrochemical energy conversion and storage technologies.…”
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Enhanced Alkaline Water Electrolysis with PrBa0.5Sr0.5Co1.5Fe0.5O5+δ‐IrO2 Composite: Synergistic Catalytic Performance via Electronic Structure Modulation by Zixuan Fan, Yaowei Liu, Jianqiang Wang, Lakshya Mathur, Sivaprakash Sengodan, Bingbing Niu, Guntae Kim

“…This study highlights the PBSCF‐Ir composite as an efficient and durable catalyst for AWS, thereby addressing the need for sustainable hydrogen production.…”
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Direct extraction of respiratory information from pulse waves using a finger-inspired flexible pressure sensor system by Xikuan Zhang, Jin Chai, Lingxiao Xu, Shixuan Mei, Xin Wang, Yunlong Zhao, Chenyang Xue, Yongjun Wang, Danfeng Cui, Zengxing Zhang, Haiyan Zhang, Libo Gao

“…We have successfully demonstrated a stable, cost-effective, and durable respiratory sensor system that can quantitatively collect and store respiratory data for individuals and groups. …”
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Sustainable Bi-directional thermoregulation fabric for clothing microclimate by Yanyan Lin, Chengran Qu, Xueqin Li, Chengfeng Ding, Xianfeng Wang, Jianyong Yu, Bin Ding

“…Herein, we report a sustainable and durable bi-directional thermoregulation fabric (Bi-DTF) by hierarchical structural engineering strategy. …”
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The human STING agonist E7766 induces immunogenic tumor clearance, independent of tumor-intrinsic STING expression in the KRASG12D/+ Trp53−/− murine model of sarcoma by Karys M. Hildebrand, Kurt N. Hildebrand, Carolina Salazar Arcila, Kayla Marritt, Jahanara Rajwani, Golpira Elmi Assadzadeh, Antoine Dufour, Frank R. Jirik, Michael J. Monument

“…Using STING deficient mice, and CRISPR/Cas9 gene editing, we demonstrated that STS clearance following STING therapy was dependent on host STING and not tumor-intrinsic STING pathway functionality. E7766 represents a promising candidate able to remodel the TME of murine STS tumors toward an inflamed phenotype independent of tumor-intrinsic STING functionality, and should be considered for potential translation in STS treatment.…”
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Impact of Temperature Stresses on Wheat Quality: A Focus on Starch and Protein Composition by Pei Han, Yaping Wang, Hui Sun

“…With climate change, maintaining wheat quality has become essential for the functional properties, end-use, commodity value, and nutritional benefits of wheat flour. …”
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