Ecological Concrete-Based Modular System for Heavy Metal Removal in Riparian Transition Zones: Design, Optimization and Performance Evaluation by Guangbing Liu, Da Ke, Hasnain Moavia, Chen Ling, Yanhong Zhang, Yu Shen

“…Through systematic optimization, we developed a C25-grade ecological concrete module (100 mm × 100 mm × 100 mm) with a specialized cavity design (φ61 mm × H60 mm) that achieves optimal balance between structural integrity (20–30 MPa compressive strength) and environmental functionality (>15% porosity, >1 × 10⁻⁴ cm s⁻¹ permeability). …”
Get full text

Le passé morcelé : du rebut, du matériau et de l’œuvre d’art by Laura Foulquier

“…In a way, these practices often signify loss, if not disappearance. The initial function of the recovered elements is completely disrupted: these elements were part of a whole, now irreparably fragmented. …”
Get full text

Neurotransmitters: an emerging target for therapeutic resistance to tumor immune checkpoint inhibitors by Jiyuan Yang, Yu Wu, Xinhui Lv, Sicong Liu, Ziwen Yuan, Yafang Chen, Xiangyu Ding, Zhong Li, Xudong Wang

“…However, only 20% of patients experience durable efficacy, and the challenge of drug resistance limits the clinical application of these therapies. …”
Get full text

mTOR inhibition modulates vaccine-induced immune responses to generate memory T cells in patients with solid tumors by Li Yan, Nina Bhardwaj, Tibor Keler, Kunle Odunsi, Song Liu, Junko Matsuzaki, Takemasa Tsuji, Mark Long, Thinle Chodon, Emese Zsiros, Protul Shrikant, Jianming Wang, Alan Hutson, Stephanie Blank, Amit Lugade, Richard Koya, Spencer R Rosario, Henry G Withers, Shashikant B Lele

“…Further studies are warranted to identify the impact of this approach on the durability of clinical remission.Trial registration number NCT00803569, NCT01536054, NCT01522820.…”
Get full text

Improved longevity and in vivo performance of neurotransmitter detection using 30 µm cone-shaped carbon fiber microelectrode by Haeun Kwon, Hyun-U Cho, Jeongeun Sim, Kyung-Jun Boo, Kyung-Jun Boo, Yumin Kang, Sangmun Hwang, Youngjong Kwak, Jaehyun Jang, Kyung Min Kim, Se Jin Jeon, Chan Young Shin, Kevin E. Bennet, Kevin E. Bennet, Yoonbae Oh, Yoonbae Oh, Hojin Shin, Hojin Shin, Kendall H. Lee, Kendall H. Lee, Dong Pyo Jang, Dong Pyo Jang

“…To improve mechanical robustness and long-term functionality, we fabricated 30 µm diameter CFMEs and modified their geometry via electrochemical etching to form cone-shaped tips. …”
Get full text

Human IFN-κ Inhibited Respiratory RNA Virus Replication Dependent on Cell-to-Cell Interaction in the Early Phase by Weihui Fu, Peng Sun, Jun Fan, Longfei Ding, Songhua Yuan, Guanxing Zhai, Miaomiao Zhang, Chenli Qiu, Shuye Zhang, Xiaoyan Zhang, Jianqing Xu, Haijuan Wang

“…In contrast, IFN-α2 started to function later but was stronger and more durable than IFN-κ. …”
Get full text

Biomechanical Analysis of Various Connector Designs of Dental Implant Complex: A Numerical Finite Element Study by Shawkat A Elsheikh, Mohamed I El-Anwar, Tao Hong, Christoph Bourauel, Abdulaziz Alhotan, Noha M Anany, Islam G Shahin, Al-Hassan Diab, Tarek M Elshazly

“…Clinicians should weigh these biomechanical trade-offs when planning treatment, particularly in patients with high functional loads or compromised bone conditions.…”
Get full text

Active learning for advanced biodegradable film design by Yi Gao, Chengcheng Liu, Yang Zhao, Peng Zhao, Feihui Chen, Qinghai Li, Yanguo Zhang, Bin Yang, Hui Zhou

“…Ultimately, it provides an economically viable and environmentally friendly pathway toward reducing plastic waste while enhancing the functionality and commercial viability of biodegradable films.…”
Get full text

An update in the management of spinal metastases by Andrei F. Joaquim, Ann Powers, Ilya Laufer, Mark H. Bilsky

“…The principle goals of treatment are maintenance or improvement in neurologic function and ambulation, spinal stability, durable tumor control, and pain relief. …”
Get full text

Green Doping and Dual‐Mode Confinement in SnS2‒P‒SPAN Anodes: Unveiling High‐Performance Sodium/Potassium Ion Full‐Cells Across the Wide Temperature Ranges by Yiyi Wang, Wenbin Lai, Fuyu Xiao, Mingyang Ge, Fenqiang Luo, Xiang Hu, Renpin Liu, Peixun Xiong, Qinghua Chen, Qingrong Qian, Zhenhai Wen, Lingxing Zeng

Get full text

Nanoscaffold Ba0.6Sr0.4TiO3:Nd2O3 ferroelectric memristors crossbar array for neuromorphic computing and secure encryption by Weifeng Zhang, Jikang Xu, Yongrui Wang, Yinxing Zhang, Yu Wang, Pengfei Li, Yongqing Jia, Zhen Zhao, Changliang Li, Biao Yang, Yue Hou, Zhenqiang Guo, Zeze Huang, Yincheng Qi, Xiaobing Yan

“…This device demonstrates a widely tunable ferroelectric domain range (0°–180°), high remnant polarization (21.04 μC/cm2), and a greater number of unitary states (16 states or 4 bits). It exhibits high durability, enduring over 109 switching cycles. The switching mechanism combines ferroelectric polarization and oxygen vacancy migration, enabling the simulation of biological synaptic functions via bi-directional conductance tunability. …”
Get full text

Constitutive model of metal rubber material considering plastic accumulation behavior by FENG Zhipeng, YANG Fang, FU Hailong, AI Shigang, WANG Yue, YUAN Liangyang

“…Metal rubber, as a novel functional material characterized by its unique three-dimensional reticulated porous structure, has demonstrated significant application value in aerospace engine mounts, aircraft landing gear buffer systems, satellite vibration damping devices, and precision vibration isolation systems for intelligent equipment, owing to its exceptional energy dissipation capacity, remarkable temperature resistance, and excellent environmental adaptability. …”
Get full text

Clientelistic linkages in the Western Balkans: DALP II expert survey evidence by Bliznakovski Jovan

“…Relational clientelism, or patronage, emerges as the dominant form, extending beyond electoral goals to function as an organizing principle within party structures. …”
Get full text

Case Report: Exploring the spectrum of A20 haploinsufficiency in children by Sahana Jayaraman, Nayimisha Balmuri

“…The A20 protein restrains NF-κB–mediated pro-inflammatory signaling; therefore, loss-of-function variants unleash widespread inflammation that can involve virtually any organ. …”
Get full text

Outcomes of Bilateral Scandinavian Total Ankle Replacement: A Detailed Analysis of Implant Survivability and Patient-Reported Outcomes by Alexandra Hunter Aitchison BS, Albert T. Anastasio MD, Kevin A. Wu BS, Emily Poehlein MB, Cynthia Green PhD, Samuel B. Adams MD, James K. DeOrio MD, Mark E. Easley MD, James A. Nunley MD

“…Conclusion: At midterm follow-up, patients who underwent bilateral simultaneous TAR with the STAR prosthesis experienced a significant and durable improvement in patient-reported outcome scores across multiple functional indices. …”
Get full text

Aripiprazole Lauroxil: Development and Evidence-Based Review of a Long-Acting Injectable Atypical Antipsychotic for the Treatment of Schizophrenia by Citrome L, Correll CU, Cutler AJ, Dunbar M, Hoberg AR, Hopkinson C, Mattingly GW, McGrory JA, Rege B, Weiden PJ, McDonnell D

“…Pharmacokinetic, efficacy, and safety characteristics support the use of AL across inpatient and outpatient treatment settings.Plain Language Summary: Treatment of schizophrenia with continuous antipsychotic medication has been shown to improve symptoms, daily functioning, and quality of life. One important option for antipsychotic treatment is a long-acting injectable medication. …”
Get full text

A randomized controlled trial of anodal transcranial direct current stimulation (A-tDCS) and olfactory training in persistent COVID-19 anosmia by Lucilla Vestito, Marta Ponzano, Laura Mori, Carlo Trompetto, Fabio Bandini, Riccardo Canta, Anna De Giovanni, Simone Strano, Andrea Pagani

“…Conclusion: This RCT demonstrates that combining A-tDCS with concurrent OT is able to restore the olfactory function in individuals suffering from persistent COVID-19 anosmia, with a durable effect. …”
Get full text

How Much Rationality Is Needed for Decision Making? by Annette Grathoff

“…With the perspective that the evolution of information processing systems is already beginning in a physical and chemical pre-biotic world, this is an interesting case that might give further insight into how and when choices between many possibilities could threaten the function of a system rather than making it more durable and adaptable. …”
Get full text

Action of selective serotonin reuptake inhibitor on aggressive behavior in adult rat submitted to the neonatal malnutrition by Jairza Maria Barreto Medeiros, Cristiano Mendes da Silva, Everton Botelho Sougey, José Audisio Costa, Célia Maria M. Barbosa de Castro, Raul Manhães de Castro

“…Thus, the malnutrition during the critical period of brain development seems to induce durable alterations in the function of the serotoninergic neurotransmission…”
Get full text

Circular Thinking In A Technological Age: Designing For A Regenerative Future by Mohammed Ali Berawi, Perdana Miraj, Mustika Sari

“…CE and technology cannot function without the active participation of its citizens. …”
Get full text