Hierarchically mimicking outer tooth enamel for restorative mechanical compatibility by Junfeng Lu, Jingjing Deng, Yan Wei, Xiuyi Yang, Hewei Zhao, Qihan Zhao, Shaojia Liu, Fengshi Li, Yangbei Li, Xuliang Deng, Lei Jiang, Lin Guo

“…Abstract Tooth enamel, and especially the outer tooth enamel, is a load-resistant shell that benefits mastication but is easily damaged, driving the need for enamel-restorative materials with comparable properties to restore the mastication function and protect the teeth. Synthesizing an enamel analog that mimics the components and hierarchical structure of natural tooth enamel is a promising way to achieve these comparable mechanical properties, but it is still challenging to realize. …”
Get full text

Immunotherapy resistance in non-small cell lung cancer: from mechanisms to therapeutic opportunities by Huiyu Wang, Xiaomin Niu, Zhenning Jin, Shaoxing Zhang, Rong Fan, Hua Xiao, Shen S. Hu

“…Moreover, the review explores bispecific antibodies, antibody-drug conjugates, and small-molecule agents that enhance T cell function or disrupt immunosuppressive signaling networks. …”
Get full text

Micro-friction mechanism characterization of particle-reinforced multilayer systems of 316L and 430L alloys on grey cast iron by Mohammad Masafi, Heinz Palkowski, Hadi Mozaffari-Jovein

“…Given the critical safety-related function of GJL brake discs, it is of paramount importance to avoid manufacturing defects in the coatings applied to them. …”
Get full text

Evaluation of the mechanical characteristics of bagasse ash concrete using response surface methodology by Uzoma Ibe Iro, George Uwadiegwu Alaneme, Nakkeeran Ganasen, M. VishnuPriyan, Imoh Christopher Attah, Val Hyginus Udoka Eze, Bamidele Charles Olaiya, Somtochukwu Ejeabukwa

“…Abstract Assessing the mechanical properties of Sugarcane Bagasse Ash (SCBA) concrete is essential for improving its strength and durability while ensuring its viability as a sustainable building material. …”
Get full text

Effectiveness of acupuncture for post-stroke aphasia: protocol for a systematic review and meta-analysis by Junzhe Jia, Yuanli Shan, Yihe Tang, Qiang Tang

“…The primary outcomes will be changes in overall language function (e.g., using the Western Aphasia Battery) and functional communication ability (e.g., using the Communicative Effectiveness Index). …”
Get full text

Investigating the Use of Luminous Capsule Bubble Tiles in Smart Structures to Improve Reflexology by Mukilan Poyyamozhi, Panruti Thangaraj Ravichandran, Kavishri Bharathidass, Balasubramanian Murugesan, Kanniappan Vadivelan, Majed Alsafyani, Waleed Nureldeen, Narayanamoorthi Rajamanickam

“…Each tile contains multiple pressure point capsules featuring a copper cap that emits electromagnetic waves when exposed to sunlight. This dual-function mechanism stimulates acupressure points on the feet, promoting better blood circulation, reducing stress, and enhancing relaxation. …”
Get full text

Impact of pelletisation on torrefied oil palm empty fruit bunch biochar by Mat Rasat Mohd Sukhairi, Mohd Amin Mohamad Faiz, Ahmad Muhammad Iqbal, Mohamed Noor An’amt, Moktar Janshah, Mohd Yunus Ag Ahmad, Jemali Noor Janatun Naim, Abdul Majid Nur Kyariatul Syafinie, Amaludin Nazahatul Anis, Bukhari Siti Noor Balqis, Darus Dasrul Iskandar, Abas Muhamad Azahar, Abd Ghani Muhammad Aizat, Mohd Amin Mohamad Asyraf

“…Results indicate that pelletisation significantly affects the structural integrity and functional properties of torrefied EFB biochar. Pellets exhibit enhanced bulk density and durability, which are beneficial for storage and transport. …”
Get full text

Basic principles and technologies for planted forests and nature-oriented forests in arid conditions by Manaenkov Alexander

“…The purpose of this work is to systematize the achievements of science and practice in the field of forest land reclamation, aimed at increasing the effectiveness of work, productivity and functional durability of forest crops on sands and zonal soils of dry sub-humid and semi-arid regions. …”
Get full text

Deciphering a volcano-shaped relationship between radical stability and reticular electrochemiluminescence by Haocheng Xu, Rengan Luo, Haifeng Lv, Tianrui Liu, Qiaobo Liao, Yandong Wang, Ziyan Zhong, Xiaojun Wu, Jianping Lei, Kai Xi

“…Abstract Electrochemiluminescence (ECL) is a light-emitting process in which the stability of electrochemically generated radicals has a crucial impact on the efficiency and durability of excited state generation. Therefore, deciphering a relationship between radical stability and ECL performance is highly appealing. …”
Get full text

Fast and precise tongue pressure measurement by intraoral laser-induced graphene pressure sensor for elderly healthcare by Hyeonwoo Kim, Han Ku Nam, Tongmei Jing, Dongwook Yang, Younggeun Lee, Yong Kwon Chae, Seoung-Jin Hong, Sang Wook Kang, Young-Jin Kim

“…Tongue pressure (TP) monitoring is essential for evaluating oral functions and improving elderly healthcare, particularly in addressing challenges related to chewing, swallowing, and speech. …”
Get full text

Ghana’s 2020 electoral politics: an assessment of the electoral commission by Akpeko Agbevade

“…The independence of election management bodies is very crucial for the durability and success of every democracy. This paper assessed the independence of Ghana’s Electoral Commission in the conduct of the December 2020 elections using the de jure election management body’s independence framework of institutional, financial, functional and personnel. …”
Get full text

Approximation of the Profile of Gas Turbine Engine Blades by M. E. Soloviev, Y. N. Shuleva, S. L. Baldaev, L. Kh. Baldaev

“…Introduction. Increasing the durability of gas turbine engine (GTE) blades is achieved through the use of special protective coatings on their surface. …”
Get full text

Whole-Body Cryotherapy Reduces Systemic Inflammation in Healthy Adults: Pilot Cohort Study by Elizabeth Chun, Richard Joseph, Rachele Pojednic

“…Biomarkers were modeled as linear functions of W-BC sessions received in the month prior to blood draw. …”
Get full text

FSI modeling and simulation of blood viscosity impacts on cavitation in mechanical heart valves by Joseph Amponsah, Archibong Archibong-Eso, Aliyu M. Aliyu, Tabbi Wilberforce Awotwe

“…This durability makes tMHVs particularly suitable for patients under 60. …”
Get full text

Current trends in the creation of cell-free allo- and xenotissues for reconstruction of heart structures by S. I. Babenko, R. M. Muratov, M. N. Sorcomov

“…Tissue engineering has significant potential for solving the problems of durability of biological tissues when used in cardiac and vascular reconstructive surgery. …”
Get full text

Numerical and experimental analyses of a steel “Y” joint with damage by Marko Milošević, Dragoslav Stojić, Srđan Živković, Dragan S. Jovanović

“…Steel damage can significantly impact steel elements’ performance, affecting other structural and non-structural building parts and compromising safety and functioning. Understanding the processes and mechanisms of steel structure damage is crucial for improving its durability. …”
Get full text

Tissue Engineering of Muscles and Cartilages Using Polyelectrolyte Hydrogels by Hyuck Joon Kwon

“…The prevalent nature of osteoarthritis that causes the erosion of joint surfaces and loss of mobility and muscle dystrophy that weakens the musculoskeletal system and hampers locomotion underlies the importance of developing functional replacement or regeneration of muscle and cartilage tissues. …”
Get full text

Advances in CAR optimization strategies based on CD28 by Sijin Li, Sijin Li, Sijin Li, Yusi Zhou, Yusi Zhou, Yusi Zhou, Hairong Wang, Hairong Wang, Hairong Wang, Gexi Qu, Gexi Qu, Gexi Qu, Xuan Zhao, Xuan Zhao, Xuan Zhao, Xu Wang, Xu Wang, Xu Wang, Rui Hou, Zhangchun Guan, Zhangchun Guan, Zhangchun Guan, Dan Liu, Dan Liu, Dan Liu, Junnian Zheng, Junnian Zheng, Ming Shi, Ming Shi, Ming Shi

“…All marketed CAR-T products are second-generation CAR-T cells containing co-stimulatory structural domains, and co-stimulatory molecules are critical for CAR-T cell activation and function. Although CD28-based co-stimulatory molecules have demonstrated potent cytotoxicity in the clinical application of CAR-T cells, they still suffer from high post-treatment relapse rates, poor efficacy durability, and accompanying severe adverse reactions. …”
Get full text

MATHEMATICAL SUBSTANTIATION OF THE USE OF DIFFERENT TYPES OF CLAMMERS DURING THE RESTORATION OF THE DENTITION WITH DOUBLE-SIDED DISTAL DEFECTS AND THE DEFECT INCLUDED IN THE FRONTA... by R.V. Kozak, D.M. Korol

“…The basic conditions that ensure good functional qualities and durability of prosthetic structures from the point of view of biomechanics, undoubtedly include an optimal way of fixing a partial removable prosthesis, which consists in the correct choice of the clamping system that ensures reliable fixation of the prosthesis in the given position and at the same time causing a minimum of harm supporting teeth, as well as the most rational distribution of occlusal loads transmitted to the supporting tissues, since it is these factors that determine the durability functioning dentures. …”
Get full text

Efficacy and safety of B/F/TAF in treatment-naïve and virologically suppressed people with HIV ≥ 50 years of age: integrated analysis from six phase 3 clinical trials by Cissy M. Kityo, Samir K. Gupta, Princy N. Kumar, Amy R. Weinberg, Bhumi Gandhi-Patel, Hui Liu, Jason T. Hindman, Jürgen K. Rockstroh

“…Conclusions These results highlight the durability, long-term efficacy, safety, and overall benefits of B/F/TAF in PWH ≥ 50 years of age.…”
Get full text