Exploring the Perilous Nature of Phytophthora: Insights into Its Biology, Host Range, Detection, and Integrated Management Strategies in the Fields of Spices and Plantation Crops by William Jeyakumar Joel Clement, Krishnan Kalpana, Karuppiah Eraivan Arutkani Aiyanathan, Muthusamy Ramakrishnan, Aravindaram Kandan, Karunakaran Manonmani, Iruthayarajan Yesuraja, Kuttalingam Gopalasubramanian Sabarinathan, Madhavan Lysal Mini, Mookiah Shanthi, Jacop Rajangam, Ayyar Punitha

“…Therefore, eradicating or controlling Phytophthora is a highly challenging process due to the longevity of its infective propagules in soil. …”
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A novel homozygous W99G mutation in CLDN-16 gene causing familial hypomagnesemic hypercalciuric nephrocalcinosis in Turkish siblings by Caner Alparslan, Elif Perihan Öncel, Sinem Akbay, Demet Alaygut, Fatma Mutlubaş, Mansur Tatlı, Martin Konrad, Önder Yavaşcan, Belde Kasap-Demir

“…Mutations in CLDN-16 and CLDN-19 genes are associated with disrupted magnesium handling in the thick ascending limp of Henle`s loop. Patients with mutations in these genes share similar clinical features, and those with CLDN-19 gene mutations have ocular findings in addition. …”
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Comparative Mitogenomic Analysis of Three <i>Chionea</i> Species (<i>Tipulomorpha</i>: <i>Limoniidae</i>): Insights into Phylogenetic Relationships and Selection Pressure by Yufeng Feng, Wei Cen, Kenneth B. Storey, Lingjuan Liu, Danna Yu, Jiayong Zhang

“…The three mitogenomes of <i>Chionea</i> exhibit characteristic features typical of insect mitogenomes, comprising 13 protein-coding genes (PCGs), 2 ribosomal RNA genes (16S rRNA and 12S rRNA), 22 transfer RNA genes (tRNA), and a single non-coding control region (D-loop). Notably, the secondary structure of trnS1 lacks the DHU arm in all three samples, and UUA (Leu) emerges as the most frequently utilized codon. …”
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Video Segmentation of Wire + Arc Additive Manufacturing (WAAM) Using Visual Large Model by Shuo Feng, James Wainwright, Chong Wang, Jun Wang, Goncalo Rodrigues Pardal, Jian Qin, Yi Yin, Shakirudeen Lasisi, Jialuo Ding, Stewart Williams

“…To demonstrate the effectiveness of the tool, three cases are demonstrated: online wire position closed-loop control, droplet transfer behaviour analysis, and assembling a dataset for dedicated deep learning segmentation models. …”
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Sustainable management of Cuba’s fresh supply chain from the perspective of Marx’s metabolism by Lihua Hu, Chengjiu Wang, Ping He

“…First of all, from the perspective of Marx’s metabolism, this paper deeply reveals the characteristics of Cuba’s fresh supply chain and provides the author with the inventory management mode and macro basis with the control theory as the technical means. Secondly, based on the H∞ control theory, the switching control model integrating decentralized and combined inventory is innovatively designed, and the linear matrix inequality method is used to construct the demand fluctuation suppression mechanism, which significantly reduces the bullwhip effect; Thirdly, the dynamic correlation function between fresh-keeping efforts and supply chain profits is established to quantitatively verify the Pareto improvement space of supplier retailer revenue improvement under collaborative inventory mode; Finally, the governance framework of “political-ecological supply chain” is proposed to realize metabolic repair from three dimensions: the closed-loop system of agricultural products based on circular economy reconstructs the material flow, the precise inventory management under the support of digital twin technology optimizes the energy exchange, and the ecological compensation mechanism led by community cooperatives reconciles the value distribution. …”
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New Insights Into the Population Structure of Hector's Dolphin (Cephalorhynchus hectori) Revealed Using Environmental DNA by S. M. Bennington, S. D. Bourke, S. P. Wilkinson, N. Englebert, D. M. Bond, G.‐J. Jeunen, S. Dawson, E. Slooten, P. W. Dillingham, W. J. Rayment, A. Alexander

“…We targeted a 348 bp region of the cetacean D‐loop in the mitochondrial DNA (mtDNA) and obtained positive detections in 68 (77%) water samples, confidently identifying seven haplotypes across the study area. …”
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Perioperative acute kidney injury in surgical treatment of renal cancer: pathogenesis, therapy of early and late complications by S. V. Popov, R. G. Guseynov, Ye. V. Pomeshkin, K. V. Sivak, V. V. Perepelitsa, K.  A. Nadein, N. S. Bunenkov, A. S. Ulitina

“…The development of acute renal injury is due to a number of factors both on the part of the patient (age, concomitant pathology, objective status) and the oncological process (stage of the disease, localization, volume of surgical intervention, access, etc.). …”
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Neural substrates of neuropsychological profiles in dystrophynopathies: A pilot study of diffusion tractography imaging. by Laura Biagi, Sara Lenzi, Emilio Cipriano, Simona Fiori, Paolo Bosco, Paola Cristofani, Guia Astrea, Antonella Pini, Giovanni Cioni, Eugenio Mercuri, Michela Tosetti, Roberta Battini

“…Our results suggest that altered WM connectivity and reduced fibre organization in cerebellar tracts, probably due to the lack of dystrophin in the brain, may render less efficient some neuropsychological functions in children affected by dystrophinopathies. …”
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Development and validation of genome-informed and multigene-based qPCR and LAMP assays for accurate detection of Dickeya solani: a critical quarantine pathogen threatening the pota... by Shefali Dobhal, Gem Santillana, Michael J. Stulberg, Dario Arizala, Anne M. Alvarez, Mohammad Arif

“…The diagnostics methods are critical in monitoring the latent infection for international trade of potato seed tubers and in implementation of control strategies. Our study employed a whole-genome comparative approach, identifying unique target gene loci (LysR and TetR family of transcriptional regulators gene regions) and designing loop-mediated isothermal amplification (LAMP) and a multi-gene-based multiplex TaqMan qPCR assays for specific detection and differentiation of D. solani. …”
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Phase-Resolved Functional Lung MRI Evaluation of Dynamic Hyperinflation Induced by Metronome-Paced Tachypnea in Patients with Chronic Obstructive Pulmonary Disease by R. A. Müller, F. Klimeš, A. Voskrebenzev, L. Behrendt, T. F. Kaireit, M. Wernz, M. Zubke, A. L. Kern, M. R. Prince, W. Shen, C. B. Cooper, R. G. Barr, J. M. Hohlfeld, J. Vogel-Claussen

“…The MPT-induced change of regional ventilation homogeneity (flow volume loop cross-correlation, FVL-CCMPT/RTB) increased with age in healthy volunteers (p = 0.039) likely due to the development of compensatory dystelectasis in younger volunteers leading to reduced homogeneity during MPT. …”
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A chemical autonomous robotic platform for end-to-end synthesis of nanoparticles by Fan Gao, Hongqiang Li, Zhilong Chen, Yunai Yi, Shihao Nie, Zihao Cheng, Zeming Liu, Yuanfang Guo, Shumin Liu, Qizhen Qin, Zhengjian Li, Lisong Zhang, Han Hu, Cunjin Li, Liang Yang, Yunhong Wang, Guangxu Chen

“…Specifically, the platform employs a Generative Pre-trained Transformer (GPT) model to retrieve methods/parameters and implements an A* algorithm centered closed-loop optimization process. It achieves optimized diverse nanomaterials (Au, Ag, Cu2O, PdCu) with controlled types, morphologies, and sizes, demonstrating efficiency and repeatability. …”
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Research Progress on Wet Recovery of Zinc Metal from Blast Furnace Smelting Dust by Lijuan JIA, Shaoxiang YANG, Linjie YANG, Jiayu FENG, Shuo CUI, Fang WANG, Yanzhang LIU, Ping NING

“…In the future, efforts should integrate the design of mineral phase reconstruction with the development of green leaching agents. A closed-loop recycling process should be established, along with the construction of a multi-technology synergy and intelligent control system. …”
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Generating Mechanism of Online Public Opinion Heat in Public Emergencies from the Perspective of Information Ecology: Fuzzy Set Qualitative Comparative Analysis Based on 50 Cases by YOU Ge, LI Jielin, ZHANG Fangshun

“…These findings will provide valuable insights for effectively managing and controlling online public opinion during emergencies. …”
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Design considerations for optogenetic applications of soft micro-LED-based device systems across diverse nervous systems by Ju Young Lee, Taemin Kim, Shinil Cho, Jiho Shin, Woon-Hong Yeo, Tae Soo Kim, Ki Jun Yu

“…Among light sources for delivering light to genetically modified cells, bio-implants integrated with Light Emitting Diodes (LEDs) have recently been the focus of extensive research due to their advantage of enabling local photogeneration. …”
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Metal–organic nanostructures based on sono/chemo-nanodynamic synergy of TixOy/Ru reaction units: for ultrasound-induced dynamic cancer therapy by Tao Jiang, Zixiang Tang, Shumiao Tian, Haitian Tang, Zhekun Jia, Fangjian Li, Chenyue Qiu, Lin Deng, Lang Ke, Pan He, Gang Liu, Chengchao Chu, Yongfu Xiong

“…Abstract Sonodynamic therapy (SDT) exhibits clinical potential for deep-tissue tumor treatment due to its deep tissue penetration and spatiotemporal controllability. …”
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Balancing LncRNA H19 and miR‐675 Bioconversion as a Key Regulator of Embryonic Myogenesis Under Maternal Obesity by Yao Gao, Md Nazmul Hossain, Liang Zhao, Xiangdong Liu, Yanting Chen, Jeanene Marie Deavila, Mei‐Jun Zhu, Gordon K. Murdoch, Min Du

“…H19 contains a G‐rich loop, and KH‐type splicing regulatory protein (KHSRP) mediates the biogenesis of pre‐miRNAs containing G‐rich loops, which depends on its phosphorylation by AKT, a key mediator of IGF2 signalling. …”
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Molecular characterization of VP1 gene during the foot and mouth disease virus outbreak in East Java, Indonesia, in 2022 by Zayyin Dinana, Suwarno Suwarno, Imam Mustofa, Jola Rahmahani, Kusnoto Kusnoto, Aussie Tahta Maharani, Anisa Lailatul Fitria, Adiana Mutamsari Witaningrum, Firdausy Kurnia Maulana, Nur Saidah Said, Deka Uli Fahrodi, Fedik Abdul Rantam

“…Conclusion: The spread of the subtype O/ME-SA/Ind2001e in South-east Asia caused an outbreak in Indonesia due to less stringent animal traffic control measures. …”
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Dragonfly Molecular Diagnostic Platform: A Rapid Point-of-Care Solution for Monkeypox and Skin Lesion Pathogens by Dr Kenny Cardenas, Dr Matthew Cavuto, Dr Marcus Pond, Dr Ivana Pennisi, Mr Sohail Mirza, Mr Mark Comer, Dr Isobel Stokes, Dr Sian Lant, Dr Rebecca P Sumner, Dr Luca Miglietta, Dr Frankie Bolt, Prof Alison Holmes, Prof Shiranee Sriskandan, Dr David O Ulaeto, Dr Carlos Maluquer de Motes, Dr Jesus Rodriguez-Manzano

“…Under-detection and misdiagnosis due to atypical presentation drove explosive dissemination, underscoring the urgency for rapid differential point-of-care diagnostic solutions for sensitive routine specimen testing. …”
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Delivery of miR-26a-5p by Subcutaneous Adipose Tissue-Derived Extracellular Vesicles Alleviates Acute Lung Injury in Mice Through CHUK/NF-&amp;kappa;B Pathway by Xie Y, Ran L, Yue C, Wang C, Chen F, Su Y, Qin Y, Zhang Q, Liu J, Du N, Zhang L, Jiang Y, Liu G

“…Notably, SAT-EVs transferred miR-26a-5p to alveolar macrophages, which directly targeted conserved helix-loop-helix ubiquitous kinase (CHUK), a key regulator of the NF-κB pathway. …”
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How seasonal hydroclimate variability drives the triple oxygen and hydrogen isotope composition of small lake systems in semiarid environments by C. Voigt, C. Voigt, F. Gázquez, F. Gázquez, L. Martegani, L. Martegani, A. I. Sánchez Villanueva, A. I. Sánchez Villanueva, A. Medina, R. Jiménez-Espinosa, J. Jiménez-Millán, M. Rodríguez-Rodríguez

“…Hydrological mass balance calculations indicate that precipitation, basin discharge, and evaporation control lake water level changes in Laguna Honda, and major inflow from other sources, such as groundwater, is absent. …”
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