In Silico Evaluation of Pharmacokinetics and Toxicity Profile of AlkaloidsPresent in Leaves of Catharanthus roseus L. by Ramgopal M Dhanwad, Usha R, Ganesh S

“…Toxicology and pharmacokinetic features were determined using the ADMETtab server.Results The study collected data on the pharmacokinetic and toxicological properties of various alkaloids along with their drug-likeness scores. Among the selected alkaloids Vinblastine showed the highest drug-likeness score. …”
Get full text

Genomic evolution of porcine reproductive and respiratory syndrome virus (PRRSV) isolates revealed by deep sequencing. by Manreetpal Singh Brar, Mang Shi, Raymond Kin-Hi Hui, Frederick Chi-Ching Leung

“…Overall, 0.56-2.83% of sites were found to be polymorphic with respect to cognate consensus genomes. The distribution of minor variants across each genome was not uniform indicating the influence of selective forces. …”
Get full text

Synthesis, ADME, and In Silico Molecular Docking Study of Novel N-Substituted <i>β</i>-Carboline Analogs as a Potential Anticancer Agent by Sunil Gaikwad

“…In silico <b>ADME</b> prediction involves using computational methods to assess the absorption, distribution, metabolism, and excretion of compounds, as well as forecasting their drug-like properties.…”
Get full text

Microstructure Evolution and Performance of AA2024 Alloy Through Wire-Arc Additive Manufacturing Under Different Heat Inputs by Jin Yang, Aimin Wang

“…As the heat input increased, α (Al) and θ (CuAl₂) phases were increasingly identified within the specimens, the grid-like distribution of the θ phase along the crystal boundaries became clearer, and the θ′ phase precipitation decreased. …”
Get full text

Retrospective Evaluation of Hematological Ratios in Dogs With Nonassociative Immune‐Mediated Hemolytic Anemia: 206 Cases by Antoine A. Duclos, Luke O'Sullivan, Ciara McPhedran, Samuel Hocker, Kevin Le Boedec, Shauna Blois, Benoît Cuq

“…Glucocorticoid treatment before referral was independently associated with decreased survival, likely reflecting selection bias toward dogs with more severe disease.…”
Get full text

Macroevolutionary trends in Ceratosauria body size: insights of phylogenetic comparative methods by Enzo E. Seculi Pereyra, Damian E. Pérez, Ariel H. Méndez

“…On the other hand, Noasauridae exhibited a phylogenetic trend towards decreased body size, likely to avoid niche overlap with medium size theropods and minimize structural and maintenance cost while living in stressful environments and having a generalist diet. …”
Get full text

Self-esteem and its influence on the inclination toward esthetic dental treatments: a cross-sectional study by Zahra Ghorbani, Saharnaz Esmaeili, Soheil Shahbazi, Maryam Jarrahzadeh, Saeed Madihi

“…Participants with a history of esthetic dental treatments were also more likely to pursue further procedures (OR = 5.39, 95% CI = 2.97–9.77). …”
Get full text

Risk perception of emergency medical technicians in biological disasters: a comparison between COVID-19 and Non-COVID-19 cases by Mohammad Azim Mahmodi, Ayob Akbari, Seyyed Mohammad Reza Hosseini, Zahra Amouzeshi

“…This study employed simple random sampling to select 200 EMTs affiliated with Birjand University of Medical Sciences. …”
Get full text

Estimating an individual-level deprivation index for HIV/HCV coinfected persons in Canada. by Adam Palayew, Alexandra M Schmidt, Sahar Saeed, Curtis L Cooper, Alexander Wong, Valérie Martel-Laferrière, Sharon Walmsley, Joseph Cox, Marina B Klein, Canadian Coinfection Cohort Study Investigators

“…We fitted an item response theory model with: severity parameters (how likely an item was reported), discriminatory parameters, (how well a variable distinguished index levels), and an individual parameter (the index). …”
Get full text

Quasi-in-situ analysis of TRIP behaviors in shear zones of high-manganese steel specimen under dynamic compression by LIN Ying, WANG Qiang, YANG Ping

“…Besides, the phase distribution of grains in different locations of shear zone was analyzed. …”
Get full text

The actuator farm model for large eddy simulation (LES) of wind-farm-induced atmospheric gravity waves and farm–farm interaction by S. Stipa, A. Ajay, J. Brinkerhoff

“…Unlike conventional models like the actuator disk (AD) or actuator line (AL), the AFM utilizes a single actuator point at the rotor center and only requires two to three mesh cells across the rotor diameter. …”
Get full text

Spatial Aspects of Demographic Processes in Serbia by Nikola Krunić, Aleksandra Gajić, Danijela Srnić, Dragutin Tošić

“… Changes in the trends, distribution and structures of the population identified through censuses (such as the changes in total population, gender, educational, age and other structures) are crucial for understanding spatial phenomena and processes like urbanization. …”
Get full text

Reweighting and analysing event generator systematics by neural networks on high-level features by Amon Furuichi, Sung Hak Lim, Mihoko M. Nojiri

“…On the other hand, large event weights are required for QCD-like top jets, which leads to imperfect reweighting for both AM and ParT generator classifiers. …”
Get full text

Social behavior of proterotheriid ungulates revealed by mammal tracksites in northwest Argentina by Rocío B. Vera, Cristo O. Romano Muñoz, Verónica Krapovickas

“…Detailed analysis of track morphology, preservation, spatial distribution, and footprint orientation reveals patterns consistent with coordinated group movement. …”
Get full text

Optimized synthesis and characterization of laterite biochar composite for arsenic removal: examining colloidal stability and As(III) oxidation by Prashant Singh, Abhijit Maiti

“…In contrast, treated laterite, rich in mixed metal oxides like iron and aluminum hydroxides, enhances the adsorption capacity, selectivity, and stability of biochar. …”
Get full text

Challenges experienced by Gauteng Foundation Phase departmental heads in managing teaching and learning by Asser R. Mhlongo, Tshidisegang M. Chaane

“…Setting: The study employed purposive sampling to select participants from six primary schools in the Tshwane West region, sampling six departmental heads of the Foundation Phase. …”
Get full text

Development of Anthropometrics Database for Ages 19-21 in West Nusa Tenggara: Optimizing Secondary Data for Industrial Product Design by Fikrihadi Kurnia, Maharsa Pradityatama, Akbar Tawaqqal

“…The data followed a normal distribution with sufficient sample validity. Percentile values (P1, P5, P50, P95, P99) revealed significant variations in body dimensions, providing a robust reference for ergonomic design across sectors like creative industries, education, healthcare, and agriculture. …”
Get full text

Mapping Ammonium Flux Across Bacterial Porins: A Novel Electrophysiological Assay with Antimicrobial Relevance by Ishan Ghai

“…This work not only enhances our understanding of outer membrane permeability to small ions like ammonium, but also has implications for antimicrobial strategy development and biotechnological applications in nitrogen assimilation.…”
Get full text

Polyethylene terephthalate track etched membrane for recovery of helium from helium-nitrogen system by Bipin Chandra Nailwal, Nitesh Goswami, Jayprakash P. Nair, Biju Keshavkumar, Puthiyedath Surendran, Anit Kumar Gupta, Soumitra Kar, Asis Kumar Adak

“…The effect of incident energy of irradiation beam (Si: 70 and 90 MeV and Cl: 84, 100 and 115 MeV) and etching parameters like concentration of NaOH, temperature, UV radiation, and ultrasonication on the control and irradiated polymer films (~25 μm thickness) were studied. …”
Get full text

Complexity Analysis of Environmental Time Series by Holger Lange, Michael Hauhs

“…Further, the position of each variable in Tarnopolski diagrams is displayed and compared to reference stochastic processes, like fractional Brownian motion, fractional Gaussian noise, and β noise. …”
Get full text