Imaging characteristics of cerebral small vessel disease in high⁃altitude plateau by WANG Jun⁃shan, ZHAO Wei⁃wei, ZHUO Ma, CHEN Yu⁃xiu, ZHAO Yu⁃hua, YUAN Jing

“…The distribution patterns of CSVD imaging markers were analyzed. …”
Get full text

Effects of an interprofessional care concept in nursing homes evaluated in the SaarPHIR project: A cluster-randomized controlled trial. by Lisa Tönnies, Viola Zimmer, Alexandra Piotrowski, Thorsten Lehr, Sonja Laag, Juliane Köberlein-Neu

“…The primary outcome, hospitalization, was assessed using claims data from six health insurers. Analyses were performed using generalized linear mixed models assuming both a Poisson and, for sensitivity analyses, a negative binomial distribution allowing for clustering at the nursing home level. …”
Get full text

Insight into the management of patients with melanoma in times of the COVID-19 pandemic: A single-center experience by Nikolić Jelena, Marinković Marija, Jovanović Mladen, Mijatov Ivana, Leković-Stojanov Dragana, Kecman Stefan

“…The following data were collected and compared: patient demographics, melanoma characteristics, time intervals from biopsy to surgery, and the share of thin and thick melanoma. …”
Get full text

A multicenter retrospective study of patients with obstructive sleep apnea in two hospitals in Tibet plateau and Beijing plain by Tao Li, Zihe Lian, Yuzhi Lin, Quzhen Gesang, Liyuan Tao, Rui Fan, Pan Liu, Qucuo Meilang, Yan Yan

“…Among patients with severe OSAS in two places, the disease severity of patients in Tibet Plateau area [AHI = 62 (45.5–90.3)] was significantly higher than that in Beijing plain area [AHI = 53.8 (38.4–67), P < 0.05]. 96% of patients treated in the Tibetan plateau had LSpO2 below 80%, while 51% of patients treated in the Beijing Plain had LSpO2 below 80%. …”
Get full text

Anticancer evaluation of Myo-inositol through carbonic anhydrase IV inhibition activity: A spectroscopic, quantum computational, topological, drug-likeness and in-silico molecular... by K. Rajkumar, V. Gokulakrishnan, S. Anand, R. Durga, G. Senthilkumar, S. Sri Karthick, R. Kayalvizhi Kothai

“…A strong correlation exists between experimental data and theoretical values, indicating that myo-inositol is highly stable. …”
Get full text

The Prevalence of Multidrug-Resistant (MDR) Pseudomonas aeruginosa Isolated from Patients Suffering from Cystic Fibrosis in the World: A Systematic Review and Meta-Analysis by Jalileh Ebn Abbas, Samaneh Rouhi, Hamed Jafarpour, Khadijeh Taherkhani, Sanaz Ahmadi, Bijan Nouri, Rasool Nasiri Kalmarzi, Farshid Gholami, Arya Jafari, Nasrin Yaghoobi

“…To check the heterogeneity of the data, the Q-test (p<0.10) was used with the chi-square χ2 distribution at the 95% confidence level. …”
Get full text

Sexually Transmitted Infections among Human Immunodeficiency Virus Patients in a Tertiary Hospital in Surabaya, Indonesia by Jose Suryanegara, Nissa Avina Pilar, Cintya Dipta Riswanto, Regitta Indira Agusni, Maylita Sari, Astindari, Septiana Widyantari, Afif Nurul Hidayati, Dwi Murtiastutik

“…Researchers analyzed the medical records of HIV patients who had coexisting STIs and visited the dermatology and venereology outpatient clinic between January 2021 and December 2022. Data collected included patient demographics, STI diagnoses, and clinical characteristics. …”
Get full text

Intravenous Clarithromycin in Critically Ill Adults: A Population Pharmacokinetic Study by Reya V. Shah, Karin Kipper, Emma H. Baker, Charlotte I. S. Barker, Isobel Oldfield, Harriet C. Davidson, Cleodie C. Swire, Barbara J. Philips, Atholl Johnston, Andrew Rhodes, Mike Sharland, Joseph F. Standing, Dagan O. Lonsdale

“…<b>Methods:</b> Pharmacokinetic, clinical and demographic data were collected from critically ill adults receiving intravenous clarithromycin. …”
Get full text

Hidden Deficiency: How Metformin Use Drives Vitamin B12 Depletion in Type 2 Diabetes by Rizwan Ali Talpur, Shahzad Ali Jiskani, Muhammad Ishaque Bhatti, Anam Shaikh, Jawed Iqbal, Rida Qureshi

“…Blood samples were collected to measure serum vitamin B12 levels, and data was analyzed using SPSS 24.0. A p-value of ≤0.05 was considered statistically significant. …”
Get full text

Myofibroblast-derived extracellular vesicles facilitate cancer stemness of hepatocellular carcinoma via transferring ITGA5 to tumor cells by Yang Xiao, Ping Tao, Keke Zhang, Liuyan Chen, Jinyu Lv, Zhiwei Chen, Lu He, Hongling Jia, Jian Sun, Mingrong Cao, Jian Hong, Chen Qu

“…Co-immunoprecipitation/mass spectrometry and transcriptome data were integrated to delve into the mechanism. …”
Get full text

Implementing and validating newborn screening for inborn errors of metabolism in South India: a 2-year observational study at a tertiary care hospital by Manju Hosuru Chikkalingaiah, Supriya Bevinakoppamath, Surajj S Archana, Aishwarya Kapa, Swetha N Kempegowda, Kusuma K Shivashankar, Shobha C Ramachandra, Suma K Basavarajaiah, Suma Nataraj, Akila Prashant

“…The confirmed cases were promptly treated and monitored regularly. The distribution of each marker’s values fell within 2.5th–97.5th percentiles suggesting consistency.Conclusion The reference ranges provided by the manufacturer appear valid in the Indian context. …”
Get full text

Effectiveness of proprioceptive neuromuscular facilitation pattern on upper extremity and scapula in patients with adhesive capsulitis: a single-centre assessor-blinded randomised... by Abid Hasan Khan, Md. Saruar Hossain Bhuiyan, Md. Feroz Kabir, Md. Zahid Hossain, Sharmila Jahan, K M Amran Hossain, Ehsanur Rahman

“…The secondary outcome was functional limitation measured by the shoulder pain and disability index (SPADI). As per the distribution of data, non-parametric tests were employed to analyse the superiority between and within groups with intention-to-treat analysis. …”
Get full text

A comprehensive review on novel opportunities for Alzheimer therapy by targeting BIN1 by Trina Saha, Dipanjan Karati

“…Articles that were not written in English, treated other topics, were not examining BIN1 or Alzheimer’s disease, were abstracts from conferences, editorials, letters, short papers with missing data or repeated studies were all excluded. …”
Get full text

Ingested Foreign Bodies in Erbil by Saleh Ahmed Tawfique

“…Patients and Methods This is a prospective study where data of cases collected and saved on computer for future analysis . …”
Get full text

Final assessment of the COVID-19 pandemic impact between the different social and economic strata population of the city of Buenos Aires by Alejandro Macchia, Cristian Biscayart, Patricia Angeleri, Javier Mariani, Daniel Ferrante

“…Study design: Observational time series analysis in a large city, treated as a natural experiment. Methods: Analysis of death certificates, demographic data, and health system records of positive RT-PCR COVID-19 tests from 2015 to 2021, categorizing by age, sex, and place of residence. …”
Get full text

Application of 3D-printed compensators for proton pencil beam scanning of shallowly localized pediatric tumors by Agnieszka Wochnik, Tomasz Kajdrowicz, Gabriela Foltyńska, Dawid Krzempek, Katarzyna Krzempek, Krzysztof Małecki, Marzena Rydygier, Jan Swakoń, Paweł Olko, Renata Kopeć

“…Materials and methods This study is based on treatment planning system simulations using retrospectively selected data from six pediatric patients with diagnosed sarcomas located in the head and neck area. …”
Get full text

Efficient Sequestration of Heavy Metal Cations by [Mo₂S₁₂]²⁻ Intercalated Cobalt Aluminum-Layered Double Hydroxide by Subrata Chandra Roy, Carrie L. Donley, Saiful M. Islam

“…Our study also shows that the CoAl―Mo₂S₁₂ is a highly competent silver cation adsorbent exhibiting removal capacity (<i>q</i>_m) as high as ~918 mg/g compared with the reported data. A detailed mechanistic analysis of the post-treated solid samples with Ag⁺, Hg²⁺, and Pb²⁺ reveals the formation of Ag₂S, HgS, and PbMoO₄, respectively, suggesting the precipitation reaction mechanism.…”
Get full text

RHEUMATOID ARTHRITIS IN RHEUMATOLOGICAL CARE OF RUSSIA: THE SEVERITY OF THE DISEASE IN A RUSSIAN PATIENT POPULATION: A CROSS-SECTIONAL EPIDEMIOLOGICAL STUDY (RAISER) by O M Folomeeva, E L Nasonov, I A Andrianova, E A Galushko, D V Goryachev, T V Dubinina, A P Zhornyak, O A Krichevskaya, Sh F Erdes, O M Folomeyeva, E L Nasonov, I A Andrianova, E A Galushko, D V Goryachev, T V Dubinina, A P Zhornyak, O A Krichevskaya, Sh F Erdes

“…Objective: To study the severity of rheumatoid arthritis in a Russian patient population on the basis of the data of rheumatological care. Methods. Polyclinic and hospital rheumatologists from 27 cities and towns of Russia (a total of 30 centers) participated in the cross-sectional epidemiological study. …”
Get full text

Retrospective analysis of scleritis or peripheral ulcerative keratitis in systemic vasculitis: insights from a single tertiary centre by Lucy Hong, Rona Smith, Rachel Jones, David Jayne, Erika Damato, Kevin Loudon

“…Introduction: Ocular manifestations of systemic vasculitis are rare and often difficult to treat, resulting in increased morbidity for affected patients. …”
Get full text

Minimal Clinically Important Difference in Patients with Acute Neck Pain Undergoing Conservative Treatment with Korean Medicine by Kim JS, Kim E, Shin S, Ha IH, Lee YJ

“…Minimal detectable changes (MDCs) were estimated using a distribution-based approach.Results: The study cohort comprised 60.2% female patients with an average age of 40.7 ± 12.7 years. …”
Get full text