Optimisation of the deployment of automated external defibrillators in public places in England by Terry P Brown, Lazaros Andronis, Asmaa El-Banna, Benjamin KH Leung, Theodoros Arvanitis, Charles Deakin, Aloysius N Siriwardena, John Long, Gareth Clegg, Steven Brooks, Timothy CY Chan, Steve Irving, Louise Walker, Craig Mortimer, Sandra Igbodo, Gavin D Perkins

“…Background Ambulance services treat over 32,000 patients sustaining an out-of-hospital cardiac arrest annually, receiving over 90,000 calls. …”
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Sex and Gender Differences in Iron Chelation by Sarah Allegra, Stefano Comità, Antonella Roetto, Silvia De Francia

“…Age and hormones have an impact on the absorption, distribution, metabolism, and excretion of the medications used to treat iron excess, resulting in notable sex- and gender-related variances. …”
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Deep learning-powered radiotherapy dose prediction: clinical insights from 622 patients across multiple sites tumor at a single institution by Zhen Hou, Lang Qin, Jiabing Gu, Zidong Liu, Juan Liu, Yuan Zhang, Shanbao Gao, Jian Zhu, Shuangshuang Li

“…Methods and materials We included 622 patients with planning data across various tumor sites: nasopharyngeal carcinoma (n = 29), esophageal carcinoma (n = 82), left-sided breast carcinoma (n = 107), right-sided breast carcinoma (n = 95), cervical carcinoma treated with radical radiotherapy (n = 84), postoperative cervical carcinoma (n = 122), and rectal carcinoma (n = 103). …”
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Radiation‐associated sarcoma after breast cancer in a nationwide population: Increasing risk of angiosarcoma by Samuli H. Salminen, Mika M. Sampo, Tom O. Böhling, Laura Tuomikoski, Maija Tarkkanen, Carl P. Blomqvist

“…The 5‐year sarcoma‐specific survival was 75.1% for RAS treated with a curative intent. The distribution of histologic subtypes of RAS has changed during the 60 years of this registry study. …”
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Pulmonary hypertension in Finland 2008-2020: A descriptive real-world cohort study (FINPAH) by Markku Pentikäinen, Piia Simonen, Helena Tuunanen, Pauliina Leskelä, Terttu Harju, Pertti Jääskeläinen, Christian Asseburg, Minna Oksanen, Erkki Soini, Christina Wennerström, Airi Puhakka, Terttu Harju, Elina Heliövaara, Pertti Jääskeläinen, Katriina Kahlos, Pentti Korhonen, Tiina Kyllönen, Pauliina Leskelä, Kirsi Majamaa-Voltti, Piia Simonen, Anu Turpeinen, Helena Tuunanen, Ville Vepsäläinen, Tapani Vihinen

“…Background: To assess characteristics, risk group distribution, and prognosis of patients with pulmonary arterial hypertension (PAH) or chronic thromboembolic pulmonary hypertension (CTEPH) in Finland. …”
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Palynostratigraphy, Palaeogeography and Source Rock Evaluation of the Nayband Formation at the Parvadeh area, Central Iran, Iran by M. Ghavidel-Syooki, M. Yousefi, D. Mohnhoff

“…A total 573 samples were treated for Palynological analysis, and only 120 samples were productive. …”
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Low anterior resection syndrome after radical surgical treatment of rectal cancer: interim results of a multicenter interuniversity clinical trial by A. A. Zakharenko, M. A. Belyaev, A. A. Trushin, A. A. Svechkova, I. A. Paltyshev, A. Kh. Khamid, O. A. Ten, T. V. Kupenskaya, M. V. Zavgorodnyaya, I. A. Filatova, F. Ya. Dzhafarzadeh, K. I. Vladimirova, N. M. Guseinova, L. A. Khamid, Ya. O. Baskova, Z. U. Asadullaeva, A. E. Zolotukhina, N. V. Kim, M. Yu. Yushakov, O. A. Udoratin, A. R. Alekseeva, D. D. Shungutova, K. I. Muratova, L. I. Gainullina, S. I. Radostev, N. A. Istomina, V. A. Zlygosteva, A. V. Ivanov, I. V. Grigorieva, A. Yu. Perelygina, R. I. Moshurov, P. Yu. Petrova, P. V. Oshchepkova, G. Yu. Kiselev, I. G. Sarukhanyan, O. A. Tkachuk, E. V. Efanova, D. A. Ufilina, Yu. Yu. Kaprielova, R. N. Ganna, A. A. Lagutina, V. Yu. Leontyeva, A. I. Sudakov, A. E. Abbasov, E. S. Antipova, A. S. Mayorov, V. S. Antonov, O. A. Plotnikova, Yu. V. Pelipas

“…Depending on the type of data and the distribution of values, the methods of parametric and nonparametric statistics was used. …”
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Impact of a national tsetse control programme to eliminate Gambian sleeping sickness in Uganda: a spatiotemporal modelling study by Sophie Dunkley, Andrew Hope, Joshua Longbottom, Johan Esterhuizen, Michael J Lehane, TN Clement Mangwiro, Albert Mugenyi, Richard Selby, Inaki Tirados, Steve J Torr, Michelle C Stanton

“…The outputs provide important data for informing next steps for vector control and surveillance.…”
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Epidemiological Trends and Characteristics of Dermatological Conditions Presenting to a Saudi Major Emergency Department by Bin Rubaian NF, AlOmar RS, Alzahrani AS, Alotaibi FM, Alharbi MA, Alanazi BS, Almuhaidib SR, Alsaadoon NF, Alfaraj D, AlShamlan NA

“…The data gathered included sociodemographic variables, date and shift of visit, triage level, dermatological complaint characteristics, management, and discharge status. …”
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Novel prehospital lactate cut-off estimation for mortality: a multicentre observational study by Ancor Sanz-García, Carlos del Pozo Vegas, Daniel Zalama-Sánchez, Raúl López-Izquierdo, Francisco Martín-Rodríguez, Pedro Ángel de Santos Castro, Eduardo Silva Alvarado, Santos Gracia Villar, Luis Alonso Dzul López, Silvia Aparicio Obregón, Rubén Calderon Iglesias

“…The aim of the present work was to determine the cut-off of the lactate threshold that activates alert triggers for all-cause 2-day mortality.Design Multicentre, prospective, ambulance-based, observational study.Setting Patients treated via emergency medical services (EMSs) and delivered to the emergency department between 2019 and 2023 were selected in Spain.Participants Adults with any acute disease.Primary and secondary outcome measures Epidemiological data, vital signs and prehospital point-of-care glucose and lactate levels were obtained. …”
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Initial community response to a novel spatial repellent for malaria prevention in Busia County, Kenya by Sheila Muya Ekodir, Lucy Baker, Julius I. Odero, Jane Klein A. Ikapesi, Moureen Ekisa, Albert Casella, April Monroe, Anna Passaniti, Eric Ochomo, Steven A. Harvey

“…Abstract Background Malaria transmission in Africa significantly declined between 2005 and 2015 due to widespread distribution of insecticide-treated nets (ITNs). However, since 2015, transmission has increased due to insecticide resistance and biting at times when people are not using ITNs. …”
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Interleukin-12 Inhibits Tumor Growth and Metastasis Promoted by Tumor-Associated Mesenchymal Stem Cells in Triple-Negative Breast Cancer by Babak Jahangiri, Zahra-Soheila Soheili, Elahe Asadollahi, Mehdi Shamsara, Vahid Shariati, Alireza Zomorodipour

“…Cell proliferation was measured using trypan blue exclusiontechnique, while cell cycle distribution and apoptosis were assessed by flow cytometry. …”
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Antibodies to recombinant human alpha-L-iduronidase prevent disease correction in cortical bone in MPS I mice by Sarah C. Hurt, Steven Q. Le, Shih-hsin Kan, Quang D. Bui, Michael D. Brodt, Patricia I. Dickson

“…Failure of enzyme replacement therapy (ERT) to treat skeletal disease may be due to development of anti-IDUA antibodies, found previously to alter tissue distribution of ERT in animal models. …”
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External validation of population pharmacokinetic models of gentamicin in paediatric population from preterm newborns to adolescents by Črček Mateja, Grabnar Iztok, Zdovc Jurij Aguiar, Grosek Štefan, Kos Mojca Kerec

“…Retrospectively collected data from a routine clinical practice (512 concentrations from 308 patients) were used for validation. …”
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Human African trypanosomiasis cases diagnosed in non-endemic countries (2011-2020). by Jose R Franco, Giuliano Cecchi, Gerardo Priotto, Massimo Paone, Augustin Kadima Ebeja, Pere P Simarro, Abdoulaye Diarra, Dieudonné Sankara, Weining Zhao, Daniel Argaw Dagne

“…<h4>Methodology/principal findings</h4>Antitrypanosomal medicines to treat the disease are available gratis through the World Health Organization (WHO) thanks to a public-private partnership, and exclusive distribution of the majority of them enables WHO to gather information on all exported cases. …”
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Maximum Entropy Estimates of Hubble Constant from Planck Measurements by David P. Knobles, Mark F. Westling

“…The inferred ME value lies within 1σ of both early-universe estimates (Planck, Dark Energy Signal Instrument (DESI)) and late-universe measurements (e.g., the Chicago Carnegie Hubble Program (CCHP)) using redshift data collected from the James Webb Space Telescope (JWST). …”
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Extent of Challenges Encountered By the Araling Panlipunan and Social Science Teachers in Facilitating the Modular Distance Learning: Basis for the Formulation of Learning and Deve... by Marino Pamogas

“…Mean and standard deviation were the statistical tools used to treat the data. In a nutshell, the result reveals a moderate difficulty encountered by the teacher-respondents in facilitating modular distance learning, with an overall mean of 2.78 and a standard deviation of 0.71. …”
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The Role of the Zagros Suture on Three Dimensional Deformation Pattern in Eghlid-Deh Bid Area of Iran by K Sarkarinejad

“…Such a conclusion is in agreement with recent field surveys including micro and macro-tectonic data.…”
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OSSN in South India: Clinical presentation, treatment outcomes, and histopathologic correlations by P V Tejaswi Prasad, Shanti Radha Krishnan, Naveen Radhakrishnan, Sahithya Bhaskaran, N Venkatesh Prajna

“…Sixty-three had requisite EMR data with a follow-up period of 1 year. Results: Patients had equal gender distribution with an age range of 28–83 years. …”
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Multi-scale inference of genetic trait architecture using biologically annotated neural networks. by Pinar Demetci, Wei Cheng, Gregory Darnell, Xiang Zhou, Sohini Ramachandran, Lorin Crawford

“…This setup yields a fully interpretable neural network where the input layer encodes SNP-level effects, and the hidden layer models the aggregated effects among SNP-sets. We treat the weights and connections of the network as random variables with prior distributions that reflect how genetic effects manifest at different genomic scales. …”
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