Modulation of anti-tumour immunity by XPO1 inhibitors by Jack G. Fisher, Laura G. Bartlett, Trinayan Kashyap, Christopher J. Walker, Salim I. Khakoo, Matthew D. Blunt

“…Exportin-1 (XPO1) is a nuclear export protein that, when overexpressed, can facilitate cancer cell proliferation and survival and is frequently overexpressed or mutated in cancer patients. As such, selective inhibitors of XPO1 (XPO1i) function have been developed to inhibit cancer cell proliferation and induce apoptosis. …”
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EXPERIENCE OF SURGICAL TREATMENT OF THYROID AND PARATHYROID DISEASES by E. A. Ilyicheva, A. V. Zharkaya, D. A. Bulgatov, V. N. Makhutov, y. V. Borichevskiy, V. P. Karasev, G. Y. Aldaranov, G. A. Ovakimyan

“…Presently, we prefer thyroidectomy in the treatment of diffuse toxic goiter and multinodular goiter, hemithyroidectomy - for the single-node goiter. …”
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Xanthogranulomatous Cholecystitis Masquerading as Gallbladder Cancer: Can It Be Diagnosed Preoperatively? by Ashwin Rammohan, Sathya D. Cherukuri, Jeswanth Sathyanesan, Ravichandran Palaniappan, Manoharan Govindan

“…An accurate preoperative diagnosis requires an integrated review of clinical and characteristic radiological features, the presence of which may help avoid radical resection and avoidable morbidity in selected cases.…”
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Becker muscular dystrophy mice showed site-specific decay of type IIa fibers with capillary change in skeletal muscle by Daigo Miyazaki, Mitsuto Sato, Naoko Shiba, Takahiro Yoshizawa, Akinori Nakamura

“…BMD mice showed site-specific muscle changes, unlike mdx mice, which showed diffuse muscle changes, and we demonstrated selective type IIa fiber reduction in BMD mice. …”
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MRI features of primary cardiac lymphoma: case report and literature review by Dongmei Xie, Yudan Li, Chunyong Tang, Qing Zou

“…Initial transthoracic echocardiography detected a 4.5-cm × 5-cm mass without blood flow in the right atrium, suspected as a thrombus or tumor. …”
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Stent-induced hypersensitivity leading to refractory in-stent restenosis: a case report by Menghuai Ma, Jiong Tang

“…Intravascular ultrasound revealed diffuse neointimal hyperplasia in the in-stent restenosis lesion, and the blood tests showed no sign of systemic inflammation or infection. …”
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Modern View on the Dilated Cardiomyopathy by Yuzych I.

“…With the decrease of the contractile ability of the myocardium the likelihood of detecting the mural clots in heart chambers increases, and this can then become a source of thromboembolism. …”
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EFFICACY OF GLOFITAMAB IN PRIMARY REFRACTORY LYMPHOMA: A CASE REPORT by Muzaffer Keklık, Kemal Fıdan, Ali Unal

“…Objective: Diffuse large B-cell lymphoma (DLBCL) constitutes 30% of non-Hodgkin lymphomas and is often curable with frontline chemoimmunotherapy. …”
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Chronic Hepatitis B In Elite Athletes by T. H. Nguyen, L. Yu. Ilchenko, K. K. Kyuregyan, L. I. Melnikova, C. C. Nguyen

“…The efficacy of antiviral therapy was evaluated by virological, serological, biochemical responses and reduction of liver fibrosis severity.Results. 35.7 % of athletes periodically reported heaviness in the right hypochondrium, and 19 % experienced mild weakness. Diffuse changes in the liver were detected in two-thirds (66.7 %) of the athletes. …”
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Confirming the Tidal Tails of the Young Open Cluster Blanco 1 with TESS Rotation Periods by Lizhou Sha, Andrew M. Vanderburg, Luke G. Bouma, Chelsea X. Huang

“…Recent studies have reported the existence of diffuse tidal tails extending 50–60 pc from the cluster center based on the positions and velocities measured by Gaia. …”
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Common arterial trunk: pathomorphological changes of unoperated cardiac defect in adulthood by V. I. Hryhoriichuk, Yu. I. Kuzyk, O. I. Boiko

“…In the pulmonary tissue diffuse hemosiderosis, multiple intravalveolar hemorrhages, sclerosis of the small pulmonary arteries with the formation of two- and three-sided lumen, sclerosis of interalveolar membranes were detected. …”
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The clinical efficacy and influencing factors of uterine artery embolization in the treatment of different types of uterine adenomyosis by Wen-Jiang Wei, Zuo-Fu Tian, Hao Liu, Cheng-Jiang Xiao

“…Their serum CA125 level was detected, and the degree of symptom relief and health index were evaluated, aiming to explore the clinical efficacy and influencing factors of UAE in the treatment of adenomyosis. …”
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NR4A3 (NOR-1) Immunostaining Shows Better Performance than DOG1 Immunostaining in Acinic Cell Carcinoma of Salivary Gland: a Preliminary Study by Adepitan Owosho, Donald Tyler, Olufunlola Adesina, Oluwole Odujoko, Kurt Summersgill

“…This upregulates the transcription factor nuclear receptor subfamily 4 group A member 3, which can be detected by immunohistochemistry. The purpose of this pilot study is to evaluate the performance of nuclear receptor subfamily 4 group A member 3 immunostaining on whole-slide acinic cell carcinoma tissue, in comparison with discovered on GIST-1 immunostaining. …”
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Congenital Anomaly of Central Nervous System Associated with Antenatal Coinfection with Cytomegalovirus and Toxoplasma: Clinical Case by Natalia E. Gimaldinova, Yevgenia N. Ignatieva, Olga V. Vorobyova, Lyubov A. Lyubovtseva

“…Toxoplasmic cysts were detected in chorionic villae stroma, parietal thophoblast, amnion, decidual tissue. …”
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Soil Mapping of Small Fields with Limited Number of Samples by Coupling EMI and NIR Spectroscopy by Leonardo Pace, Simone Priori, Monica Zanini, Valerio Cristofori

“…In addition to two profiles selected by clustering, another 35 topsoil augerings (0–30 cm) were added. …”
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Minimally Invasive Treatment of Sporadic Burkitt’s Lymphoma Causing Ileocaecal Invagination by Paolo Panaccio, Michele Fiordaliso, Domenica Testa, Lorenzo Mazzola, Mariangela Battilana, Roberto Cotellese, Federico Selvaggi

“…A 31-year-old man presented with diffuse colic pain and weight loss. Clinical examination revealed an abdominal distension with pain in the right iliac fossa. …”
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Effect of Superstoichiometric Bismuth Addition on the Structure and Dielectric Characteristics of the Solid Solutions (1−<i>x</i>)BiFeO₃-<i>x</i>BaTiO₃ by Nikita A. Boldyrev, Egor S. Esin, Lidia A. Shilkina, Svetlana I. Dudkina, Alexander V. Nagaenko, Larisa A. Reznichenko

“…The grain morphology and dielectric characteristics of the selected solid solutions were investigated. The highest piezoelectric coefficient, d₃₃ = 120 pC/N, was obtained in the mechanically activated ceramics 0.71BiFeO₃-0.29BaTiO₃ + 2 wt.% Bi₂O₃.…”
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Inter-Organelle Crosstalk in Oxidative Distress: A Unified TRPM2-NOX2 Mediated Vicious Cycle Involving Ca²⁺, Zn²⁺, and ROS Amplification by Esra Elhashmi Shitaw, Maali AlAhmad, Asipu Sivaprasadarao

“…Understanding and targeting specific nodes within this TRPM2-NOX2-Ca²⁺-Zn²⁺-mtROS-ADPR axis offers novel therapeutic avenues for NCDs by selectively disrupting pathological ROS amplification while preserving essential physiological redox signalling.…”
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Analysis of the Effect of Music Therapy Interventions on College Students with Excessive Anxiety by Sha Liu, Genqiang Li

“…In order to explore and analyze the effect of music therapy interventions on college students with excessive anxiety, this paper selected 240 year 2017- to year 2020-enrolled undergraduates from a comprehensive university in Taiyuan City, Shanxi Province, in Central China as research objects. …”
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The Association between Skull Bone Fractures and the Mortality Outcomes of Patients with Traumatic Brain Injury by Yu-Chin Tsai, Cheng-Shyuan Rau, Jin-Fu Huang, Yu-Min Chang, Kai-Jay Chia, Ting-Min Hsieh, Sheng-En Chou, Wei-Ti Su, Shiun-Yuan Hsu, Ching-Hua Hsieh

“…Although skull fractures may indicate greater force impact and are associated with local or diffuse brain injuries, the prognostic value of skull fractures remains unclear. …”
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