Functions of lncRNA in the osteogenic differentiation of periodontal ligament stem cells by CAO Bangping, SU Jiansheng

Get full text

Protocol for differentiation of human embryonic stem cells into surface epithelium and functional keratinocytes by Jiafeng Liu, Huaxing Huang, Hong Ouyang

“…Here, we present a protocol to differentiate human embryonic stem cells (hESCs) into SE and subsequently into epidermal keratinocyte progenitors. …”
Get full text

Dual Function of Wnt Signaling during Neuronal Differentiation of Mouse Embryonic Stem Cells by Hanjun Kim, Sewoon Kim, Yonghee Song, Wantae Kim, Qi-Long Ying, Eek-hoon Jho

Get full text

Interleukin-17 and Its Implication in the Regulation of Differentiation and Function of Hematopoietic and Mesenchymal Stem Cells by Slavko Mojsilović, Aleksandra Jauković, Juan F. Santibañez, Diana Bugarski

Get full text

Functionality of endothelial cells differentiated from porcine epiblast stem cells, bone marrow-derived mesenchymal stem cells and adipose-derived mesenchymal stem cells by Yeon-Ji Lee, In-Won Lee, Tae-Suk Kim, Bo-Gyeong Seo, Sang-Ki Baek, Cheol Hwangbo, Joon-Hee Lee

“…The purpose of this study was to induce the differentiation of porcine epiblast stem cells (pEpiSCs), bone marrow-derived mesenchymal stem cells (pBM-MSCs) and adipose-derived mesenchymal stem cells (pA-MSCs) into ECs and then examine the functionality of vascular ECs. …”
Get full text

MicroRNA functions in osteogenic differentiation of periodontal ligament stem cells: a scoping review by Pirawish Limlawan, Pirawish Limlawan, Anjalee Vacharaksa, Anjalee Vacharaksa, Anjalee Vacharaksa

“…This scoping review aimed to describe the differential microRNA (miRNA) functions in osteogenic differentiation of periodontal ligament stem cells (PDLSCs), and then analyze the potential of applying PDLSCs and miRNAs in bone regeneration. …”
Get full text

Extremely low-frequency electromagnetic fields facilitate proliferation and functional differentiation in spinal neural stem cells by Wenxu Tang, Dan He, Xiaofei Li, Yi Feng, Yue Xu, Jiawei Hu, Wei Xu, Lei Xue

“…Abstract Traumatic spinal cord injury (SCI), typically resulting from direct mechanical damage to the spine, often leads to disruption of neural signaling and axonal conduction, severely impairing nervous system function. In rodent models of SCI, neural stem cell (NSC) transplantation has demonstrated significant potential in restoring motor function and enhancing neural repair. …”
Get full text

The secretomes of bovine mammary epithelial cell subpopulations differentially modulate macrophage function by Nikola Danev, Rebecca M. Harman, Anja S. Sipka, Leanne Oliveira, Lucas Huntimer, Gerlinde R. Van de Walle

Get full text

Regulation of stem cell fate and function by using bioactive materials with nanoarchitectonics for regenerative medicine by Wei Hu, Jiaming Shi, Wenyan Lv, Xiaofang Jia, Katsuhiko Ariga

“…Besides multipotent differentiation, immunomodulation is an important biological function of mesenchymal stem cells (MSCs). …”
Get full text

Cardiac Differentiation of Pluripotent Stem Cells by Kristiina Rajala, Mari Pekkanen-Mattila, Katriina Aalto-Setälä

“…The ability of human pluripotent stem cells to differentiate towards the cardiac lineage has attracted significant interest, initially with a strong focus on regenerative medicine. …”
Get full text

Differential regulation of apoptosis-related genes during long-term culture and differentiation of canine adipose-derived stem cells - a functional bioinformatical analysis by Maurycy Jankowski, Maurycy Jankowski, Maurycy Jankowski, Katarzyna Stefańska, Michał Suchodolski, Claudia Dompe, Claudia Dompe, Grzegorz Wąsiatycz, Bartosz Kempisty, Bartosz Kempisty, Bartosz Kempisty, Bartosz Kempisty, Michał Nowicki, Magdalena Roszak

Get full text

The redox function of APE1 is involved in the differentiation process of stem cells toward a neuronal cell fate. by Rossana Domenis, Natascha Bergamin, Giuseppe Gianfranceschi, Carlo Vascotto, Milena Romanello, Silvia Rigo, Giovanna Vagnarelli, Massimo Faggiani, Piercamillo Parodi, Mark R Kelley, Carlo Alberto Beltrami, Daniela Cesselli, Gianluca Tell, Antonio Paolo Beltrami

“…Therefore, E3330 may be employed both to boost neural differentiation and to bias the differentiation potential of stem cells towards specific neuronal subtypes. …”
Get full text

Dental pulp stem cells conditioned medium-functionalized microspheres for endodontic regeneration by Jing Gao, Jing Gao, Yuhan Wang, Yuhan Wang, Tongxing Zhang, Jiafei Qu, Jiafei Qu, Qian Liu, Yao Chen, Yao Chen, Baoshan Xu, Jing Shen, Jing Shen

“…However, recreating the native pulp microenvironment remains a critical challenge.MethodsThis study developed a novel strategy to mimic the dental pulp regeneration microenvironment using nucleus pulposus microspheres (NPM) loaded with conditioned medium (CM) for dental pulp stem cells (DPSCs). The biocompatibility of NPM and the effects of NPM-loaded CM on DPSCs differentiation and angiogenesis were systematically evaluated. …”
Get full text

Uncoupling protein 2 and 4 expression pattern during stem cell differentiation provides new insight into their putative function. by Anne Rupprecht, Dana Sittner, Alina Smorodchenko, Karolina E Hilse, Justus Goyn, Rudolf Moldzio, Andrea E M Seiler, Anja U Bräuer, Elena E Pohl

“…To verify this hypothesis, we analyzed the expression of UCP1-5 in mouse embryonic stem cells before and after their differentiation to neurons. …”
Get full text

Dexamethasone-Functionalized PLLA Membranes: Effects of Layer-by-Layer Coating and Electrospinning on Osteogenesis by Flavia Gonçalves, Roberta Molisani Letomai, Marjory Muraro Gomes, Maria dos Remédios Aguiar Araújo, Yasmin Silva Muniz, Maria Stella Moreira, Leticia Cidreira Boaro

Get full text

Metabolic Mechanism of Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cell Regulated by Magnetoelectric Microenvironment by Han Zhao, Fangyu Zhu, Yusi Guo, Xuliang Deng, Wenwen Liu

Subjects: Get full text

PTPN21 Overexpression Promotes Osteogenic and Adipogenic Differentiation of Bone Marrow-Derived Mesenchymal Stem Cells but Inhibits the Immunosuppressive Function by Huafang Wang, Xiaohang Ye, Haowen Xiao, Ni Zhu, Cong Wei, Xiang Sun, Limengmeng Wang, Binsheng Wang, Xiaohong Yu, Xiaoyu Lai, Shan Fu, He Huang

“…In the study, we explored the effects of PTPN21 on human bone marrow-derived mesenchymal stem cells (BM-MSCs) via lentiviral-mediated overexpression and knock-down of PTPN21 in vitro. …”
Get full text

Highly efficient generation of mature megakaryocytes and functional platelets from human embryonic stem cells by Chuxin Chen, Ning Wang, Xueyan Zhang, Yingjie Fu, Zhiyong Zhong, Haibin Wu, Yaming Wei, Yuyou Duan

“…Abstract Background Platelet transfusion therapy has made a great breakthrough in clinical practice, and the differentiation of human embryonic stem cells (hESCs) to produce functional platelets has become a new potential approach, however, efficient generation of functional platelets still faces great challenges. …”
Get full text

The Multifaceted Roles of MicroRNA-181 in Stem Cell Differentiation and Cancer Stem Cell Plasticity by Chun Yang, Rui Wang, Pierre Hardy

“…Stem cells are undifferentiated or partially differentiated cells with an extraordinary ability to self-renew and differentiate into various cell types during growth and development. …”
Get full text

SS-31 Targets NOS2 to Enhance Osteogenic Differentiation in Aged BMSCs by Restoring Mitochondrial Function by Sen Duan, Qindong Zhang, Jinqiang Zhu, Jiaming Wang

“…This study delves into the rejuvenating effects of SS-31 on aged human Bone Marrow-Derived Mesenchymal Stem Cells (BM-MSCs), focusing on its potential to restore their diminished osteogenic differentiation capacity, a critical issue in geriatric medicine and bone tissue engineering. …”
Get full text