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The Role of Genomics and Transcriptomics in Characterizing and Predicting Patient Response to Treatment in Triple Negative Breast Cancer (TNBC)
Published 2025-04-01“…These unique elements are the foundation of personalized medicine where genomics and transcriptomics play a critical role in increasing granularity in patients’ disease and treatment. …”
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683
Anatomy and transcriptomics of the common jingle shell (Bivalvia, Anomiidae) support a sensory function for bivalve tentacles
Published 2024-12-01“…In addition to applying microscopy techniques, we performed transcriptome sequencing of dissected tentacles using phylogenetically-informed annotation to identify candidate receptors. …”
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684
Single-cell transcriptomic landscape reveals complex cellular heterogeneity and dysregulated signaling pathways in nasopharyngeal carcinoma
Published 2025-05-01“…This study aimed to systematically analyze the transcriptional characteristics of different cell types in NPC and their roles in tumor development using single-cell transcriptomics. …”
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685
Transcriptomic characterization of maturing neurons from human neural stem cells across developmental time points
Published 2025-06-01“…Ion AmpliSeq™ was used for transcriptomic characterization of human stem cell-derived neurons at multiple time points. …”
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686
De novo assembly of the common bean transcriptome using short reads for the discovery of drought-responsive genes.
Published 2014-01-01“…The strategy for de novo assembly of transcriptome data generated here will be useful in other legume plant transcriptome studies. …”
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687
Combined transcriptome and proteome profiling reveal cell-type-specific functions of Drosophila garland and pericardial nephrocytes
Published 2024-11-01“…Here, we established a method for cell-specific isolation of the two types of Drosophila nephrocytes, garland and pericardial cells, from animals of different developmental stages and ages. Mass spectrometry-based proteomics and RNA-Seq-based transcriptomics were applied to characterise the proteome and transcriptome of the respective cells in an integrated and complementary manner. …”
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688
Comparative Transcriptome Analysis of Hens’ Livers in Conventional Cage vs. Cage-Free Egg Production Systems
Published 2025-01-01“…Different conditions of production systems including stocking density, thermal conditions, and behavior restriction can have a significant detrimental effect on the health and performance of laying hens. …”
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From the environment to the host: re-wiring of the transcriptome of Pseudomonas aeruginosa from 22°C to 37°C.
Published 2014-01-01“…We examined the effects of growth temperature on the transcriptome of the P. aeruginosa PAO1. Microarray analysis of PAO1 grown in Lysogeny broth at mid-exponential phase at 22°C and 37°C revealed that temperature changes are responsible for the differential transcriptional regulation of 6.4% of the genome. …”
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692
Spatial transcriptomics identifies RBM39 as a gene associated with Gleason score progression in prostate cancer
Published 2024-12-01“…Principal component analysis (PCA) and Louvain clustering analysis revealed transcriptomic classifications aligned with the histology of different GSs. …”
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693
NGS Transcriptomes and Enzyme Inhibitors Unravel Complexity of Picrosides Biosynthesis in Picrorhiza kurroa Royle ex. Benth.
Published 2015-01-01“…Retrieval of gene sequences for enzymatic steps from NGS transcriptomes and their expression analysis vis-à-vis picrosides content in different tissues/organs showed elevated transcripts for twenty genes, which were further shortlisted to seven key genes, ISPD, DXPS, ISPE, PMK, 2HFD, EPSPS and SK, on the basis of expression analysis between high versus low picrosides content strains of P. kurroa so as to eliminate tissue type/ developmental variations in picrosides contents. …”
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694
Transcriptome-aligned metabolic profiling by SERSome reflects biological changes following mesenchymal stem cells expansion
Published 2024-12-01“…By integrating these metabolic features detected by SERS with transcriptomic data, we established a correlation between SERS signals and biological changes, as well as differentially expressed genes. …”
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695
Comparative transcriptomic analysis of chicken immune organs affected by Marek’s disease virus infection at latency phases
Published 2025-04-01“…We identified genes and pathways associated with the transcriptional response to MDV infection using the robust RNA sequencing approach. The transcriptome analysis revealed a tissue-specific expression pattern among immune organs when confronting MDV. …”
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Integrated morphological observation, metabolomics, and transcriptomics to investigate the effect of growth years on the quality of Atractylodes macrocephala Koidz
Published 2025-07-01“…However, research on its quality dynamics across different growth years remains limited, primarily focusing on transcriptomics, microbiome analysis, and photosynthetic capacity, with studies only extending to three-year-old plants. …”
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698
Integrated transcriptomic and metabolomic analysis of flavonoid biosynthesis in cigar tobacco leaves under variable nitrogen regimes
Published 2025-06-01“…Given tobacco's high nitrogen demand and the particular sensitivity of flavonoid synthesis to nitrogen supply, understanding the regulatory mechanisms of flavonoid biosynthesis under varying nitrogen conditions is essential.Methods and resultsWe systematically investigated the flavonoid biosynthesis pathways in the cigar tobacco cultivar Haiyan 204 under different nitrogen application rates using integrated transcriptomic and metabolomic analyses. …”
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699
Transcriptomic Analysis Reveals the Mechanisms of Cadmium Transport and Detoxification in Portuguese Oysters (<i>Crassostrea angulata</i>)
Published 2025-04-01“…Individuals with significantly different Cd accumulation were selected for transcriptomic sequencing analysis. …”
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700
Transcriptomic and proteomic analysis of oil body associated protein dynamics in the biofuel feedstock Pennycress (Thlaspi arvense)
Published 2025-02-01“…A combination of transcriptomic and proteomic tools was used to characterize the dynamics and relative abundance of the major oil body related proteins in the Pennycress seed. …”
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