Physiological and transcriptomic profiles of tobacco seedling leaves in response to high chloride accumulation by Yunjie Wu, Jialing Lu, Dongxu Wang, Yuanyuan Li, Zhiyu Feng, Xiefeng Ye

Get full text

Dietary inulin supplementation modifies significantly the liver transcriptomic profile of broiler chickens. by Natalia Sevane, Federica Bialade, Susana Velasco, Almudena Rebolé, Maria Luisa Rodríguez, Luís T Ortiz, Javier Cañón, Susana Dunner

“…The current study investigated the differences in the hepatic transcriptome profiles between chickens supplemented with inulin (a storage carbohydrate found in many plants) and controls. …”
Get full text

Race-related host and microbe transcriptomic signatures in triple-negative breast cancer by Roshan Kumar, Susan Duyar-Ayerdi, Aishwarya Sundaresan, Vinodh Srinivasasainagendra, Chandra Sekhar Pedamallu, Michael Behring, Darshan Shimoga Chandrashekar, Isam-Eldin Eltoum, Sooryanarayana Varambally, Hemant K. Tiwari, Sadeep Shrestha, Paul L. Auer, Lubna N. Chaudhary, John R. Kirby, Clayton Yates, Upender Manne, Akinyemi I. Ojesina

“…Abstract Triple-negative breast cancer (TNBC) shows racial disparities, with higher incidence in women of African ancestry (AA) compared to European ancestry (EA). Meta-transcriptomic analysis of TNBC tumor tissues from AA (n = 17) and EA (n = 19) subjects revealed distinct microbial landscapes. …”
Get full text

Transcriptome Analysis of Gelatin Seed Treatment as a Biostimulant of Cucumber Plant Growth by H. T. Wilson, K. Xu, A. G. Taylor

“…Using mRNA sequencing based approach, transcriptomes of one- and two-week-old cucumber plants from gelatin capsule treated and nontreated seeds were characterized. …”
Get full text

A deep proteome and transcriptome abundance atlas of 29 healthy human tissues by Dongxue Wang, Basak Eraslan, Thomas Wieland, Björn Hallström, Thomas Hopf, Daniel Paul Zolg, Jana Zecha, Anna Asplund, Li‐hua Li, Chen Meng, Martin Frejno, Tobias Schmidt, Karsten Schnatbaum, Mathias Wilhelm, Frederik Ponten, Mathias Uhlen, Julien Gagneur, Hannes Hahne, Bernhard Kuster

“…Abstract Genome‐, transcriptome‐ and proteome‐wide measurements provide insights into how biological systems are regulated. …”
Get full text

Tissue-specific transcriptomic adaptation in three strains of chickens during coinfections with parasites by Oyekunle John Oladosu, Henry Reyer, Nares Trakooljul, Solvig Görs, Cornelia C. Metges, Gürbüz Daş

“…This study investigated transcriptomic adaptation of tissues two weeks after experimental coinfections with Ascaridia galli, Heterakis gallinarum, and H. meleagridis in Lohmann Brown (LB), Lohmann Dual (LD), and Ross-308 (R) male chickens, which differ in growth rates (R > LD > LB). …”
Get full text

Transcriptome Differential Expression Regulation Analysis of the Narrow-Leaf Mutant of Sorghum Bicolor by Jinhong Li, Yiwei Wang, Yuche Zhao, Shirui Zhang, Chunyu Wang, Ling Cong, Yanpeng Zhang, Shuang Gang, Xiaochun Lu

“…Compared with the WT leaves, there were significant differences in leaf width and length at the flowering stage. …”
Get full text

Bile acid synthesis, modulation, and dementia: A metabolomic, transcriptomic, and pharmacoepidemiologic study. by Vijay R Varma, Youjin Wang, Yang An, Sudhir Varma, Murat Bilgel, Jimit Doshi, Cristina Legido-Quigley, João C Delgado, Anup M Oommen, Jackson A Roberts, Dean F Wong, Christos Davatzikos, Susan M Resnick, Juan C Troncoso, Olga Pletnikova, Richard O'Brien, Eelko Hak, Brenda N Baak, Ruth Pfeiffer, Priyanka Baloni, Siamak Mohmoudiandehkordi, Kwangsik Nho, Rima Kaddurah-Daouk, David A Bennett, Shahinaz M Gadalla, Madhav Thambisetty

Get full text

Profiling the full-length transcriptome of plasma cell mastitis via nanopore sequencing by Su Li, Hongyue Chen, Yan Fan, Can Wang, Lijing An, Qifeng Xu, Wenming Cai, Suzhen Zhao, Tian Tian, Baoyong Zhang, Mengmeng Yang, Lulu Zhang

“…Abstract Introduction In this study, we aimed to determine the transcriptomic profile of plasma cell mastitis (PCM) and elucidate its underlying mechanisms using nanopore sequencing technology (ONT). …”
Get full text

Multi-transcriptomics reveals niche-specific expression programs and endothelial cells in glioblastoma by Jiukun Hu, Xiaohan Sa, Yue Yang, Yuwen Han, Jie Wu, Minxuan Sun, Shaheryar Shafi, Nafees Ahmad, Sami Siraj, Jiao Yang, Yuanshuai Zhou

“…Methods Here, using bulk RNA sequencing, spatial transcriptomic and single cell RNA sequencing (scRNA-seq) data of GBM patients, we identified niche-specific transcriptional programs and characterized the differences in molecular expression and cellular organization between PAN and MVP. …”
Get full text

Transcriptomic evidence for atopic dermatitis as a systemic disease in NC/Nga mice by Young-Won Kim, Eun-A Ko, Jehee Jang, Seohyun Jeong, Donghyeon Kim, Jung Soo Suh, Se-Yeon Lee, Inja Lim, Sung-Cherl Jung, Jung-Ha Kim, Tong Zhou, Hyoweon Bang, Jae-Hong Ko

“…The expression of Ces1d showed significant differences during disease onset and after treatment in both skin and skeletal muscle, suggesting that Ces1d is likely responsible for the alleviation of subchronic AD. …”
Get full text

Single-cell transcriptome analysis reveals cellular heterogeneity in the aortas of Takayasu arteritis by Na Gao, He Tang, Taotao Li, Yi Yang, Honglei Zhao, Longfei Wang, Yanqiu Guo, Bokang Qiao, Lili Pan

“…Results Single-cell transcriptome analysis identified 11 predominant cell types in aortic tissues, with notable differences in proportions between TAK patients and controls. …”
Get full text

Plasticity of thermal tolerance and associated gill transcriptome in ballan wrasse (Labrus bergylta) by Peter Almaiz Palma, Michaël Bekaert, Alejandro P. Gutierrez, Elfred John C. Abacan, Herve Migaud, Mónica B. Betancor

“…Gill transcriptomic profiles of ballan wrasse were performed following thermal acclimation and subsequent exposure to CTmax and CTmin. …”
Get full text

Evaluation of the Effects of Acorns on the Meat Quality and Transcriptome Profile of Finishing Yuxi Pigs by Jinzhou Zhang, Chuankuan Zhang, Shuaitao Meng, Heming Wang, Dongyang Liu, Liping Guo, Zhiguo Miao

“…The mRNA levels of <i>MYH7</i>, <i>MYH2</i>, and <i>MYH1</i> were significantly upregulated in the AC2 group (<i>p</i> < 0.05). A transcriptome analysis further revealed significant differences in gene expression patterns between the AC2 and CN groups. …”
Get full text

Transcriptomics and Metabolomics Reveal the Dwarfing Mechanism of Pepper Plants Under Ultraviolet Radiation by Zejin Zhang, Zhengnan Yan, Xiangyu Ding, Haoxu Shen, Qi Liu, Jinxiu Song, Ying Liang, Na Lu, Li Tang

“…However, no significant differences were observed in the chlorophyll content of pepper plants grown under natural light and supplementary UV-B radiation. …”
Get full text

Unveiling racial disparities in prostate cancer using an integrative genomic and transcriptomic analysis by Abdalla Elbialy, Akshay Sood, Shang-Jui Wang, Peng Wang, Ahmed Fadiel, Anil V. Parwani, Steven Huang, Gennady Shvets, Nagireddy Putluri, Jenny Li, Xuefeng Liu

“…Understanding the complex interplay of genetic, environmental, lifestyle, socioeconomic, and healthcare access factors is crucial for developing effective interventions to reduce this disproportionate burden.This study aims to uncover the genetic and transcriptomic differences driving these disparities through a comprehensive analysis using RNA sequencing (RNA-seq) and exome sequencing of prostate cancer tissues from both Black and White patients.Our transcriptomics analysis revealed enhanced activity in pathways linked to immune response and cellular interactions in AA prostate cancer samples, with notable regulation by histone-associated transcription factors (HIST1H1A, HIST1H1D, and HIST1H1B) suggests potential involvement of histone modification mechanisms. …”
Get full text

Unraveling the transcriptomic effects of leucine supplementation on muscle growth and performance in basketball athletes. by Sinan Wang, Weishuai Guo, Rui Dong

“…Transcriptomic analysis revealed 3,658 differentially expressed genes (DEGs) between the two groups. …”
Get full text

Metabolomic and transcriptomic analyses unveil the accumulation of shikimic acid in the leaves of Ginkgo biloba by Wanwen Yu, Minyue Cai, Chenxi You, Wenxuan Wei, Huimin Liu

“…Concurrently, we analyzed downstream metabolites including flavonoids, phenylalanine, tryptophan and tyrosine, along with transcriptomic and metabolomic profiles in HS and LS.ResultsThe concentrations of flavonoids, phenylalanine, tryptophan and tyrosine in HS were markedly lower than those in LS. …”
Get full text

Generation and characterization of novel transcriptome-derived SSR markers for genetic applications in blueberry by Krishnanand P. Kulkarni, Richmond K. Appiah, Jennifer Johnson-Cicalese, Nicholi Vorsa, Umesh K. Reddy, Sathya Elavarthi, Hamed Bostan, Massimo Iorizzo, Kalpalatha Melmaiee

“…In this study, we developed novel transcriptome-derived simple sequence repeat (SSR) markers from two divergent blueberry species. …”
Get full text

Hippocampal Transcriptome Analysis in a Mouse Model of Chronic Unpredictable Stress Insomnia by Shuo Zhang, Changqing Tong, Na Cao, Dong Tian, Linshan Du, Ya Xu, Weiguang Wang, Zijie Chen, Shuangqing Zhai

Get full text