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2761
A R1-type MYB CmREVEILLE2 regulates light-mediated chlorophyll biosynthesis and green color formation in chrysanthemum flowers
Published 2025-05-01“…A R1-type MYB transcription factor, CmREVEILLE2 (CmRVE2), was identified through transcriptomic analysis of flowers subjected to different light intensities (3,000 Lux for low light, LL; 6,000 Lux for moderate light, ML; and 12,000 Lux for high light, HL). …”
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2762
Multi-Omics and Functional Insights into Triterpenoid Biosynthesis Pathways in <i>Neopicrorhiza scrophulariiflora</i> (Pennell) D.Y.Hong
Published 2025-05-01“…However, the molecular mechanisms of triterpenoid biosynthesis in <i>N. scrophulariiflora</i> remain unclear. Here, transcriptomic and metabolomic analyses were performed to investigate the triterpene content in different tissues and the expression patterns of key enzyme-encoding genes related to triterpenoid biosynthesis. …”
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2763
PPM1J regulates meat quality feature and glycerophospholipids composition in broiler by modulating protein dephosphorylation
Published 2024-11-01“…Here, metabolomics and transcriptomics were used to systematically identify the genetic regulation of differences in meat flavor among different broiler. …”
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2764
The glutamate receptor gene GLR3.3: A bridge of calcium-mediated root development in poplar
Published 2024-11-01“…In this study, we analyzed the morphological and transcriptomic variations of 84K poplar (Populus alba × P. glandulosa) in response to different calcium concentrations and found that low Ca2+ (1 mmol · L−1) promoted lateral root development, while deficiency (0.1 mmol · L−1 Ca2+) inhibited lateral root development. …”
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2765
CHH demethylation in the ZmGST2 promoter enhances maize drought tolerance by regulating ROS scavenging and root growth
Published 2025-08-01“…In this study, using PEG6000 and 5-azadC to treat different drought-tolerant maize inbred lines (drought-tolerant R99 and drought-sensitive Mo17), combined with transcriptomic analysis, identified the gene ZmGST2 as being related to drought resistance. …”
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2766
Significance of host antimicrobial peptides in the pathogenesis and treatment of acne vulgaris
Published 2024-12-01“…., genetically distinct bacterial subgroups that play different roles in skin health and disease) diversity of the predominant skin bacterial commensal - Cutinbacterium acnes. …”
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2767
Genome-wide identification and characterization of the bZIP family in the Mangrove Plant Kandelia obovata and its role in response to stress
Published 2025-02-01“…The expression patterns of KobZIP genes across different tissues and under various abiotic stress conditions were analyzed using transcriptomic data and experimental validation. …”
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2768
Transcriptions of ACO and ACS genes are involved in nitrate-dependent root growth of maize seedlings
Published 2025-05-01“…We discovered that ACO and ACS genes have different regulatory modes in response to nitrate provision. …”
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2769
M1hot tumor-associated macrophages boost tissue-resident memory T cells infiltration and survival in human lung cancer
Published 2020-10-01“…Immunohistochemistry related the distribution of TAM transcriptomic signatures to density of CD8+ tissue-resident memory T cells (TRM) in tumors and survival data from an independent cohort of 393 patients with lung cancer.Results TAMs have significantly different transcriptomic profiles from NTAMs with >1000 differentially expressed genes. …”
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2770
CAFs activated by YAP1 upregulate cancer matrix stiffness to mediate hepatocellular carcinoma progression
Published 2025-04-01“…By calculating intercellular communication probabilities and analyzing transcription factor activity, the functions and interactions of different CAF subsets were elucidated. Gene Ontology (GO) analysis was used to explore the functional roles of CAFs in distinct Yes-associated protein 1 (YAP1) groups. …”
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2771
SNP rs615552 and lncRNA CDKN2B-AS1 influence brain cancer pathogenesis through multi-omic mechanisms
Published 2025-07-01“…Bulk RNA-seq, spatial, and single-cell transcriptomic analyses revealed that CDKN2B-AS1 is predominantly expressed in malignant and dendritic cells (DCs), and is associated with DNA repair pathways in malignant cells and antigen presentation genes in DCs. …”
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2772
Cyclic Peptide MV6, an Aminoglycoside Efficacy Enhancer Against <i>Acinetobacter baumannii</i>
Published 2024-12-01“…Further research, including transcriptomic analysis, is essential to elucidate MV6’s role in enhancing netilmicin efficacy and its resistance mechanisms.…”
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2773
Differential Mitochondrial Genome Expression of Four Skink Species Under High-Temperature Stress and Selection Pressure Analyses in Scincidae
Published 2025-03-01“…To validate these findings, transcriptomic profiling was conducted to assess mitochondrial protein-coding gene (PCG) expression patterns under thermal stress. …”
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2774
Human Fibroblast Growth Factor 9 Induces Hair Follicle Cycle Transition via TGF-β/BMP/Smad Pathway
Published 2025-04-01“…Histological analysis revealed that intradermal injections of rhFGF9 enhanced hair follicle development. Transcriptomic analysis revealed that the mechanism underlying this effect might involve the transforming growth factor-β (TGF-β) signaling pathway. …”
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2775
Genomic subtypes of non-muscle-invasive bladder cancer: guiding immunotherapy decision-making for patients exposed to aristolochic acid
Published 2025-04-01“…We performed whole-exome sequencing (WES) and RNA sequencing (RNA-seq) to obtain detailed genomic and transcriptomic data. We subjected these datasets to genomic analysis and subtype analysis to gain valuable insights into NMIBC. …”
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2776
Circular Nucleic Acids Act as an Oncogenic MicroRNA Sponge to Inhibit Hepatocellular Carcinoma Progression
Published 2025-05-01“…Furthermore, we compared the immune effects in vivo of three different nucleic acid adsorption carriers, including commercial miRNA inhibitor, circDNA, and circRNA. …”
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2777
Liposomal Nanoparticle Delivery of Ginkgo Flavone Glycosides Enhances SIRT1 Activation and Improves Diabetic Cardiomyopathy
Published 2025-06-01“…Network pharmacology, transcriptomic analysis, and molecular docking studies were conducted to elucidate the key role of SIRT1 in inhibiting DCM progression. …”
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2778
Single-cell characterization of the immune heterogeneity of pulmonary hypertension identifies novel targets for immunotherapy
Published 2025-02-01“…We demonstrated the transcriptomic features of different cell types in PAH patients. …”
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2779
Common molecular links and therapeutic insights between type 2 diabetes and kidney cancer.
Published 2025-01-01“…The statistical LIMMA approach was used based web-tool GEO2R to detect differentially expressed genes (DEGs) through transcriptomics analysis. Then upregulated and downregulated DEGs for T2D and KC were combined to obtained shared DEGs (sDEGs) between T2D and KC. …”
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2780
Virocell resource manipulation under nutrient limitation
Published 2025-07-01“…Using multi-omics approaches, we examined how two different viruses (PSA-HP1 and PSA-HS2) independently infecting the same marine heterotrophic bacterium (Pseudoalteromonas) respond to phosphorus limitation. …”
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