TRANSCRIPTOMIC DIFFERENCES IN MONOZYGOTIC TWINS WITH OVARIAN CANCER by Gözde Kuru Türkcan, Demet Akdeniz Ödemiş, Büşra Kurt Gültaşlar, Şeref Buğra Tunçer, Seda Kılıç Erciyas, Özge Şükrüoğlu Erdoğan, Hülya Yazıcı

“…Objectives: The most significant barrier to treating epithelial ovarian cancer(EOC), is the late diagnosis and the emergence of chemotherapy resistance in the early stages.The ineffectiveness of standard treatment protocols in advanced-stage cases highlights the value of individualized EOC treatment.Even monozygotic(MZ) twins, with almost the same genotype in nature, can develop different phenotypic characteristics throughout life. …”
Get full text

Transcriptome profiling of cervical cancer cells acquired resistance to cisplatin by deep sequencing by Yamin Wang, Linna Liu, Zhong Chen

Get full text

Different Species of Bats: Genomics, Transcriptome, and Immune Repertoire by Huifang Wang, Hao Zhou, Xinsheng Yao

“…Integrated genomic, transcriptomic, and immune repertoire analyses reveal that bats employ distinct antiviral strategies, primarily mediated by enhanced immune tolerance and suppressed inflammatory responses. …”
Get full text

Sex Differences in Brain Transcriptomes of Juvenile Cynomolgus Macaques by Nadia Kabbej, Frederick J. Ashby, Alberto Riva, Paul D. Gamlin, Ronald J. Mandel, Aishwarya Kunta, Courtney J. Rouse, Coy D. Heldermon

“…Our results provide pre-pubertal information on sexual differences in non-human primate brain transcriptomics and may provide insight into health disparities between the biological sexes in humans.…”
Get full text

A Comparative Transcriptomic Analysis of miRNAs and Their Target Genes During the Formation of Melanin in <i>Apis mellifera</i> by Xiangjie Zhu, Yuanmingyue Tian, Mingjie Cao, Chenyu Zhu, Jiaqi Shang, Jiaqi Sun, Yiming Liu, Bingfeng Zhou, Shujing Zhou, Xinjian Xu

Get full text

Comparing the Transcriptomes of Two Different Tissues in Helicoverpa assulta (Guenée) by Hailing Zhang, Kuiyin Li, Yubo Zhang

“…Helicoverpa assulta (Guenée), a moth species belonging to the Noctuidae (Lepidoptera) family, is a destructive agricultural pest that infests multiple cash crops. To assess differences in the gene expression profiles of different tissues in H. assulta, we analyzed the transcriptomes of two tissue types (midgut and hemocytes) using the Illumina Hiseq 2000 platform, on the basis of which we obtained 52076750 and 53404200 high-quality clean reads, respectively. …”
Get full text

Physiology and transcriptome of Eucommia ulmoides seeds at different germination stages by Jia Liu, Sumei Qiu, Tingting Xue, Yingdan Yuan

“…Furthermore, we confirmed that ABA, GA, and IAA are essential hormones in the germination of E. ulmoides seeds using Gene Ontology and Kyoto Encyclopedia of Genes and Genomics enrichment analyses of the transcriptome. The discovery of hormone-related synthesis pathways in the control group of Eucommia seeds at different germination stages further confirmed this conclusion. …”
Get full text

Effects of different temperatures on chondrocyte growth: a transcriptomic analysis by Wei Zhao, Yingsong Wang, Jingming Xie, Jin Zhou, Zhi Zhao, Tao Li, Zhiyue Shi, Jie Xiao

Get full text

Transcriptomic difference analysis of Meyerozyma guilliermondii in response to salt stress by CAO Xuan, ZHENG Xiaodong

“…Based on the above results, the transcriptome sequencing of the strain cultured under salt stress and non-salt stress for 24 h was constructed by Illumina HiSeq^TM in this study. …”
Get full text

Interspecies differences in the transcriptome response of corals to acute heat stress by Jeric Da-Anoy, Niño Posadas, Cecilia Conaco

Get full text

Transcriptomic sex differences in early human fetal brain development by Federica Buonocore, Jenifer P. Suntharalingham, Olumide K. Ogunbiyi, Aragorn Jones, Nadjeda Moreno, Paola Niola, Tony Brooks, Nita Solanky, Mehul T. Dattani, Ignacio del Valle, John C. Achermann

“…We therefore undertook transcriptomic analysis of 46,XY and 46,XX human brain cortex samples (n = 64) at four different time points between 7.5 and 17 weeks post conception (wpc), in two independent studies. …”
Get full text

Transcriptome and metabolome analysis reveals different photosynthetic characteristics of mulberry trees with different ploidy levels by Dan Liu, Qiang Lin, Sheng Huang, Rongli Mo, Xiaomei Lu, Yanrong Zeng, Guangshu Zhu, Chaohua Zhang, Changyu Qiu

“…To evaluate the photosynthetic characteristics of mulberry trees with different ploidy levels, which determine the number of chromosome sets in a cell or organism, we compared the microstructural features and transcriptomes of triploid and diploid mulberry trees. …”
Get full text

Identification of key genes related to growth of largemouth bass (Micropterus salmoides) based on comprehensive transcriptome analysis by Dayan Hu, Jieliang Jian, Jinpeng Zhang, Xiaojun Xu, Shu Wang, Cuiping Gong, Yuanqin Zhang, Pengcan Zhu, Zhimin Gu, Wenzhi Guan

Subjects: Get full text

Single cell transcriptomic analysis reveals transcriptome differences of different cells between eosinophilic chronic rhinosinusitis with nasal polyps and non-eosinophilic chronic rhinosinusitis with nasal polyps. by Ying Jin, Yuanshan Liang, Zhijun Wang, Yiting Jiang, Fayang Yuan, Tian Zhang

Get full text

Exploring the Metabolic and Transcriptomic Profiles of Tetrastigma hemsleyanum for Tissue-Specific Compound Accumulation by Lingxia Peng, Hongju Li, Lijun Yang, Zongsuo Liang, Zongsuo Liang, Xiaodan Zhang

“…To explore the medicinal components from different parts of the plant and to fully utilize T. hemsleyanum, this study investigated the mechanisms underlying the differential accumulation of metabolites in its tuberous roots, fibrous roots, and leaves.MethodsThis study employed a combination of metabolomics and transcriptomics to analyze the metabolic profiles of T. hemsleyanum. …”
Get full text

Transcriptome comparison revealed the difference in subcutaneous fat metabolism of Qinghai yak under different feeding conditions. by Weiqin Ding, Yonggang Sun, Yincang Han, Yaqian Liu, Shengwei Jin

“…In order to explore the differences in subcutaneous fat metabolism and pathway information in yaks under different feeding conditions, this experiment used Illumina high-throughput sequencing technology to sequence the transcriptome of subcutaneous fat tissues of yaks under different feeding conditions and analyzed them bioinformatically. 9 naturally grazed yaks at 18 months of age were randomly divided into 3 groups, one group (G18_SF) was slaughtered, one group (G24_SF) continued to graze until 24 months of age was slaughtered, and one group (F24_SF) was housed until 24 months of age was slaughtered, and subcutaneous fat tissue was collected from the back of the yaks. …”
Get full text

Transcriptome Analysis of Two Different Developmental Stages of Paeonia lactiflora Seeds by Yonglei Ma, Jinqiu Cui, Xiujun Lu, Lijie Zhang, Zhijing Chen, Riwen Fei, Xiaomei Sun

“…We used high-throughput transcriptome sequencing on two different developmental stages of P. lactiflora seeds to identify seed dormancy and germination-related genes. …”
Get full text

Analysis of reproductive hormones and transcriptomics in the hypothalamus and pituitary under different photoperiods by Mengqian Liu, Lei Tan, Xinlu Li, Haojie Li, Yong Zhang, Xiannian Zi, Changrong Ge, Kun Wang

“…Select the two groups with the greatest differences in reproductive hormones for transcriptomic analysis. …”
Get full text

Defining the transcriptome and proteome in three functionally different human cell lines by Emma Lundberg, Linn Fagerberg, Daniel Klevebring, Ivan Matic, Tamar Geiger, Juergen Cox, Cajsa Älgenäs, Joakim Lundeberg, Matthias Mann, Mathias Uhlen

“…Thus, this study shows a path to characterize the transcriptome and proteome in human cells from different origins.…”
Get full text

Differences in transcriptome characteristics and drug repositioning of Alzheimer's disease according to sex by Jingqi Shi, Minghua Zhang, Yazhuo Hu, Jing Liu, Ke Li, Xuan Sun, Siyu Chen, Jianwei Liu, Ling Ye, Jiao Fan, Jianjun Jia

“…By drug repositioning, several drugs, including torin-2 and YM-298198, might have the potential to therapeutic value of MCI or AD, while drugs like homoharringtonine and teniposide have potential opposite effects in different sexes. Conclusion: The characteristics of the transcriptome in peripheral blood and single-cell transcriptome in the prefrontal cortex exhibit significant differences between male and female patients with AD, which providing a basis for future sex stratified treatment of AD.…”
Get full text