Epigenetic Contribution of High-Mobility Group A Proteins to Stem Cell Properties by Vincenzo Giancotti, Natascha Bergamin, Palmina Cataldi, Claudio Rizzi

“…High-mobility group A (HMGA) proteins have been examined to understand their participation as structural epigenetic chromatin factors that confer stem-like properties to embryonic stem cells (ESCs), induced pluripotent stem cells (iPSCs), and cancer stem cells (CSCs). …”
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Global proteomics reveals pathways of mesenchymal stem cells altered by Mycobacterium tuberculosis by Simran Kaur, Nupur Angrish, Madavan Vasudevan, Garima Khare

“…We found that virulent M. tb infection reshapes host pathways such as stem cell differentiation, alternative splicing, cytokine production, mitochondrial function etc., which might be modulated by M. tb to persist inside this unconventional niche of human BM-MSCs. …”
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Stem Cell-Associated Proteins and Extracellular Matrix Composition of the Human Atrioventricular Junction by Annika Thorsell, Linnéa Sjölin, Evelin Berger, Anders Jeppsson, Anders Oldfors, Victoria Rotter Sopasakis, Kristina Vukusic

“…Of the total 4904 identified proteins, 1138 were differently expressed between the AVj and LV. While the top proteins in LV were involved in cardiac motor function and energy regulation, the AVj displayed proteins associated with early cardiomyocyte development, differentiation, proliferation, migration, and hypoxia. …”
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Therapeutic Effects of Mesenchymal Stem Cell Conditioned Medium in Rat Varicocele Model by Ege Can Serefoglu, Bircan Kolbasi, Muhammet Volkan Bulbul, Seda Karabulut, Cagri Cakici, Reyhan Zeynep Gundogdu Ozdemir, Ilknur Keskin

“…Purpose: This study aimed to examine the therapeutic effects of injection of conditioned medium of adipose-derived mesenchymal stem cells (ADMSC-CM) in a surgically created varicocele model in comparison with varicocelectomy. …”

Hematopoietic Stem Cells of Bone Marrow and Their Total RNA in Rat Liver Regeneration by Nina Onishchenko, Murat Shagidulin, Zalina Gonikova, Alla Nikolskaya, Ludmila Kirsanova, Artem Venediktov, Ksenia Pokidova, Egor Kuzmin, Natalia Kuznetsova, Igor Kozlov, Dmitry Telyshev, Natalia Kartashkina, Viacheslav Varentsov, Maria Timofeeva, Victor Sevastjanov, Andrei Elchaninov, Gennadii Piavchenko, Sergey Gautier

“…The liver mass enlarged mostly after apoptotic hematopoietic stem cells and total RNA. Mitotic index peaked in the group of total RNA with a lower but earlier increase for the aHSC group, and Ki-67 proliferation for the total RNA group was the highest (all the differences were significant with <i>p</i> values ˂ 0.05). …”
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Pulmonary complications in children and adolescents after allogeneic hematopoietic stem cell transplantation by A. S. Frolova, A. G. Volkova, O. V. Paina, P. V. Kozhokar, K. A. Ekushov, Zh. Z. Rakhmanova, L. A. Cvetkova, E. D. Dobrovolskaya, B. I. Smirnov, E. A. Kulagin, T. A. Bykova, E. V. Semenova, L. S. Zubarovskaya

“…Allogeneic hematopoietic stem cell transplantation (allo-HSCT) makes it possible to treat severe malignant and non-malignant hematopoietic disorders system. …”
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MicroRNAs: From Female Fertility, Germ Cells, and Stem Cells to Cancer in Humans by Irma Virant-Klun, Anders Ståhlberg, Mikael Kubista, Thomas Skutella

“…MicroRNAs, together with exosomes, have a great potential to be used for prognosis, therapy, and biomarkers of different diseases including infertility. The aim of this review paper is to summarize the existent knowledge on microRNAs related to female fertility and cancer: from primordial germ cells and ovarian function, germinal stem cells, oocytes, and embryos to embryonic stem cells.…”
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Comparison of the Biological Characteristics of Mesenchymal Stem Cells Derived from Bone Marrow and Skin by Ruifeng Liu, Wenjuan Chang, Hong Wei, Kaiming Zhang

“…Our findings provide insights into the different biological functions of both cell types.…”
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Phage-Based Artificial Niche: The Recent Progress and Future Opportunities in Stem Cell Therapy by Kshitiz Raj Shrestha, So Young Yoo

“…Thus, the niche is crucial for the effective performance of the stem cells in both in vivo and in vitro since the niche provides its functional cues by interacting with stem cells chemically, physically, or topologically. …”
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Nanog Dynamics in Mouse Embryonic Stem Cells: Results from Systems Biology Approaches by Lucia Marucci

“…Mouse embryonic stem cells (mESCs), derived from the inner cell mass of the blastocyst, are pluripotent stem cells having self-renewal capability and the potential of differentiating into every cell type under the appropriate culture conditions. …”
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Role and mechanisms of histone methylation in osteogenic/odontogenic differentiation of dental mesenchymal stem cells by Meijun Hu, Zhipeng Fan

“…The cellular microenvironment regulates the fate of stem cells and can be modified using various optimization techniques. …”
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Method of obtaining of nonneuronal cultures of astrocytes, derivated from human mesenchymal stem cells by S. M. Gramatiuk, Yu. V. Іvanova, A. A. Hudyma

“…Thus, there was demonstrated, that morphologically close astrocytic lines and single cells owes different functional profile.…”
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Interaction of noncoding RNAs with hippo signaling pathway in cancer cells and cancer stem cells by Saba Abedimanesh, Reza Safaralizadeh, Zohreh Jahanafrooz, Souzan Najafi, Mohammad Amini, Shabnam Soltani Nazarloo, Seyedeh Zahra Bahojb Mahdavi, Behzad Baradaran, Asiyeh Jebelli, Amir Ali Mokhtarzadeh

“…The Hippo signaling pathway has a regulatory function in the organogenesis process and cellular homeostasis, switching the cascade reactions of crucial kinases acts to turn off/on the Hippo pathway, altering the downstream gene expression and thereby regulating proliferation, apoptosis, or stemness. …”
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Transcriptomic network underlying physiological alterations in the stem of Myricaria laxiflora in response to waterlogging stress by Linbao Li, Yang Su, Weibo Xiang, Guiyun Huang, Qianyan Liang, Bicheng Dun, Haibo Zhang, Zhiqiang Xiao, Liwen Qiu, Jun Zhang, Di Wu

“…A total of 8714 genes in the stem of M. laxiflora were identified as differentially expressed genes (DEGs) under waterlogging stress, which could be assigned into two different subgroups with distinct gene expression patterns and biological functions. …”
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Enhancing Tendon Regeneration: Investigating the Impact of Topography on the Secretome of Adipose‐Derived Stem Cells by Qiuzi Long, Chuanquan Liu, Haotian Zheng, Mingyue Wang, Hanmei Liu, Yue Liu, Zhicheng Cao, Yuzhi Sun, Qingyun Mo, Ludvig J. Backman, Jialin Zhu, Lizhi Hu, Jinlong Huang, Wei Zhang, Jialin Chen

“…Conditioned medium (CM) is collected from ADSCs cultured on the scaffolds with different topography. The results show that CM generated from aligned structure group has a potent effect in promoting cell migration and proliferation, tenogenic differentiation, macrophage polarization toward M2 phenotype, tendon structure and mechanical function recovery. …”
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The use of stem cells and organoids for modeling host-microbe interactions in low-biomass tissues by Claire A. Shaw, Claire A. Shaw, Margo Verstrate, Kinga Graniczkowska, Katie R. Risoen, Katie R. Risoen, Pouya Dini, Bart C. Weimer, Bart C. Weimer

“…Interactions with the host microbiome and infections can both significantly impair tissue regeneration and compromise the function of stem cell–derived therapies. Therefore, a comprehensive understanding of how pathogens and the microbiome interact with stem cells and organoids is relevant for developing safe and effective regenerative medicine interventions. …”
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Optimized Method to Generate Well-Characterized Macrophages from Induced Pluripotent Stem Cells by Qimin Hai, Peter Bazeley, Juying Han, Gregory Brubaker, Jennifer Powers, Claudia M. Diaz-Montero, Jonathan D. Smith

“…The objectives of this study are to define a robust and consistent method for the differentiation of induced pluripotent stem cells (iPSCs) into macrophages that can address these needs for recurrent studies with high yields and the potential for gene editing. …”
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Emerging insights into epigenetics and hematopoietic stem cell trafficking in age-related hematological malignancies by Yang Xinyi, Reshetov Igor Vladimirovich, Narasimha M. Beeraka, Allaka Satyavathi, Dinisha Kamble, Vladimir N. Nikolenko, Allaka Naga Lakshmi, Basappa Basappa, Padmanabha Reddy Y, Ruitai Fan, Junqi Liu

“…The review specifically focuses on how immunological stressors modulate different signaling pathways that impact hematopoiesis. …”
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Identification of GRAS Gene Family in Paper Mulberry and Analysis of Its Expression in Stem Development by Tanxing CHEN, Huannan LI, Pinsheng WANG, Yajun JIANG, Jinbin XIAO, Lingmin YAN, Yang WANG, Yi FAN

“…【Method】HMM was used to identify GRAS family genes in the whole genome of paper mulberry, and the expression patterns of GRAS genes in paper mulberry stem tissues (T1-T3) with different lignification degrees were analyzed through bioinformatics methods and RNA-Seq data.…”
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Effects of combined hypoxia and irradiation on mouse bone marrow hematopoietic cells by YANG Xinhai, CHEN Fang, QUAN Yong

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