Expansion of human megakaryocyte-biased hematopoietic stem cells by biomimetic Microniche by Yinghui Li, Mei He, Wenshan Zhang, Wei Liu, Hui Xu, Ming Yang, Hexiao Zhang, Haiwei Liang, Wenjing Li, Zhaozhao Wu, Weichao Fu, Shiqi Xu, Xiaolei Liu, Sibin Fan, Liwei Zhou, Chaoqun Wang, Lele Zhang, Yafang Li, Jiali Gu, Jingjing Yin, Yiran Zhang, Yonghui Xia, Xuemei Mao, Tao Cheng, Jun Shi, Yanan Du, Yingdai Gao

“…Abstract Limited numbers of available hematopoietic stem cells (HSCs) limit the widespread use of HSC-based therapies. …”
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Stemness-driven clusters in ovarian cancer: immune characteristics and prognostic implications by Xinyan Zeng, Xinyan Zeng, Wentian Wu, Xiaoqin Li, Xiaoqin Li, Xiaorui Wu, Xiaorui Wu, Yingying Du, Ping Li, Ping Li, Ping Li

“…Single-cell RNA sequencing was used to investigate stemness-related cell types. Functional assays were conducted to validate the role of AKAP12 in OC progression.ResultsThree distinct stemness-related subgroups were identified with significant differences in prognosis and immunological features. …”
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Lactobacillus delbrueckii subsp. bulgaricus 2038 and Streptococcus thermophilus 1131 ameliorate barrier dysfunction in human induced pluripotent stem cell-derived crypt-villus stru... by Kyosuke Kobayashi, Yuri Imai, Yuka Shimizu, Isamu Ogawa, Isamu Ogawa, Takaaki Nakai, Yuri Mizuno, Yoshika Kaneda, Yumiko Watanabe-Yasuoka, Fuka Yamazaki, Junko Mochizuki, Toshihiro Sashihara, Tamihide Matsunaga, Tamihide Matsunaga, Takahiro Iwao, Takahiro Iwao

“…However, Caco-2 cells differ from living organisms in various ways. We have developed a human induced pluripotent stem cell-derived crypt-villus structural small intestine (hiPSC-SI) was established with a villus-like structure containing constituent cells of the small intestine.MethodsA hiPSC-SI and LAB co-culture model was established to assess the impact of LAB on barrier function and elucidate the underlying mechanisms.ResultsThe medium on the luminal side for co-culturing cells and bacteria was examined and determined to use Hanks’ balanced salt solution without glucose in terms of bacterial survival rate. …”
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Mesenchymal stem cell transplantation plays a role in relieving cancer pain by Wen-Jun Zhang, Dingyi Chen

“…Therefore, considerable attention has been paid to exploring prospective methods to inhibit the occurrence of these factors and relieve cancer pain. Studies on different types of pains have revealed that the transplantation of functionally active cells into the host has the pharmacological effect of producing analgesia. …”
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Neuroangiogenesis potential of mesenchymal stem cell extracellular vesicles in ischemic stroke conditions by Behnaz Mirzaahmadi, Shahin Ahmadian, Parinaz Haddadi, Parinaz Nezhad-Mokhtari, Fereshteh Vaziri Nezamdoust, Banafsheh Yalameha, Sara Aghakhani Chegeni, Somayyeh Rashidi, Akbar Mousakhani, Emel Sokullu, Hajar Shafaei, Reza Rahbarghazi, Mohammad Karimipour

“…In past decades, the discovery of stem cells and byproducts has led to promising results in in vitro settings and pre-clinical studies. …”
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Periodontal Ligament Stem Cells in the Periodontitis Microenvironment Are Sensitive to Static Mechanical Strain by Jia Liu, Qiang Li, Shiyu Liu, Jie Gao, Wen Qin, Yang Song, Zuolin Jin

“…We have previously confirmed the function impairment of periodontal ligament stem cells (PDLSCs) in the periodontitis microenvironment which might be involved in this pathological process. …”
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Animal experimental study of mesenchymal stem cells transplantation for treatment of cerebral ischemia by LI Shu-bo, JU Wen-bo, ZHOU Yan, PAN An-na, GE Shu-ling

“…To explore recovery and treatment of mesenchymal stem cells (MSCs) transplantation to treat cerebral ischemia rats. …”
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Cell-nonautonomous signaling of FOXO/DAF-16 to the stem cells of Caenorhabditis elegans. by Wenjing Qi, Xu Huang, Elke Neumann-Haefelin, Ekkehard Schulze, Ralf Baumeister

“…SHC-1 adaptor protein and AKT-1 kinase antagonize, whereas AKT-2 and SGK-1 kinases promote, this cell-nonautonomous DAF-16 function. Our data suggest that a functional balance of DAF-16 activities in different tissues determines longevity and reveals a novel, cell-nonautonomous role of FOXO/DAF-16 to affect stem cells.…”
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The RNA-binding protein Modulo promotes neural stem cell maintenance in Drosophila. by Amalia S Parra, Christopher A Johnston

“…A small population of stem cells in the developing Drosophila central nervous system generates the large number of different cell types that make up the adult brain. …”
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Mitochondrial quality control in hematopoietic stem cells: mechanisms, implications, and therapeutic opportunities by Yun Liao, Stacia Octaviani, Zhen Tian, Samuel R. Wang, Chunlan Huang, Jian Huang

“…Abstract Mitochondrial quality control (MQC) is a critical mechanism for maintaining mitochondrial function and cellular metabolic homeostasis, playing an essential role in the self-renewal, differentiation, and long-term stability of hematopoietic stem cells (HSCs). …”
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Autologous Stem Cell Transplantation in Multiple Myeloma with Renal Failure: Friend or Foe? by Hongfei Zhong, Xiaojie Xie, Gaosi Xu

“…Autologous stem cell transplantation (ASCT) is a standard treatment for multiple myeloma (MM), but the clinical response and renal curative effect in MM patients with renal failure (RF) remain controversial. …”
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Rewiring the seizing brain: stem cell grafts as neuromodulatory architects in epilepsy therapy by Zijie Wang, Yanan Ma, Xiqi Hu, Ying Xia

“…Recent studies have indicated that stem cell transplantation improves neurological function in epilepsy through multiple mechanisms. …”
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The Effects of Programmed Cell Death of Mesenchymal Stem Cells on the Development of Liver Fibrosis by Hong-wei Wu, He-dan Chen, Ya-hong Chen, Xin-li Mao, Yu-yi Feng, Shao-wei Li, Xian-bin Zhou

“…Mesenchymal stem cells have shown noticeable potential for unlimited self-renewal. …”
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Hyaluronan-Based Grafting Strategies for Liver Stem Cell Therapy and Tracking Methods by Lorenzo Nevi, Samira Safarikia, Sabina Di Matteo, Francesca Biancaniello, Michele Francesco Chiappetta, Vincenzo Cardinale

“…Hyaluronans, major components of stem cell niches, are attractive candidates for coating stem cells since they improve viability, proliferation, and engraftment in damaged livers. …”
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Phenotype and Conditioning Medium on Umbilical Cord-Mesenchymal Stem Cell (UC-MSC) by Paulus Kusnanto, Bambang Purwanto, Brian Wasita, Vitri Widyaningsih

“…Stem cells have the characteristics and ability to become themselves by performing various mitoses and differentiating different cells. …”
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Study on wettability of water stemming for blasting dust adjusted by surfactants and inorganic salts by Fengjie Chen, Zejun Zhou, Ying Liang, Xiaowen Liu, Xiaoguang Wang, Pu Wang, Bolei Chen, Yong Liang, Yawei Wang

“…There is still a lack of methods for rapid optimization of water stemming components with high wettability. Herein, blasting dust was collected from a tunnel in Chongqing (China) to investigate its removal performance by different water stemmings. …”
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Xanthohumol: Anti-Inflammatory Effects in Mechanically Stimulated Periodontal Ligament Stem Cells by Christian Niederau, René H. Tolba, Joachim Jankowski, Nikolaus Marx, Michael Wolf, Rogerio Bastos Craveiro

“…This study investigated the anti-inflammatory properties of XN in an in vitro model of compressively stimulated human periodontal ligament stem cells (hPDLSCs), which have a different function in the periodontium than the previously used cementoblasts. …”
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Stem cell exosomes: new hope and future potential for relieving liver fibrosis by Lihua Li, Yongjie Liu, Kunpeng Wang, Jinggang Mo, Zhiyong Weng, Hao Jiang, Chong Jin

“…In this review, we focus on the molecular mechanisms by which stem cell exosomes affect liver fibrosis through different pathways and their potential therapeutic targets. …”
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Long term survival analysis of cementless Spotorno femoral stem in young patients by Murat Mert, Cenk Ermutlu, Emrah Kovalak, Ethem Ünkar, Sibel Çağlar Okur

“…Spotorno stems perform equally well in all etiologies with no difference in terms of survivorship. …”
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Dynamics of polyphenolics formation in different plant parts and different growth phases of selected buckwheat cultivars by Judita BYSTRICKÁ, Alena VOLLMANNOVÁ, Eva MARGITANOVÁ, Iveta ČIČOVÁ

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