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A prognostic signature of Glutathione metabolism-associated long non-coding RNAs for lung adenocarcinoma with immune microenvironment insights
Published 2025-02-01“…A prognostic model was built with Cox and Least Absolute Shrinkage and Selection Operator (LASSO) methods and validated by Kaplan-Meier analysis, Receiver Operating Characteristic (ROC) curves, and Principal Component Analysis (PCA). Functional analysis revealed immune infiltration and drug sensitivity differences. …”
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1242
Effect of Ultra-High Pressure on the Extraction of the Free, Esterified, and Bound Phenolics from <i>Dendrobium fimbriatum</i> Hook: Chemical Constituents and Antioxidant Ability
Published 2025-04-01“…This study explores the antioxidant activity and antioxidant mechanism of phenolic compounds (including free (FP), esterified (EP), and bound phenolic (BP)) from <i>Dendrobium fimbriatum</i> Hook (DFH) stems, before and after ultra-high pressure (UHP) treatment. …”
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1243
Development and validation of disulfidptosis-related genes signature for patients with glioma
Published 2024-12-01“…The risk score was associated with HLA expression, immune checkpoint genes, immune cell infiltration, immune function, tumor mutation burden, tumor stemness score, and drug sensitivity. …”
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1244
Systematic Analysis of the <i>Betula platyphylla TCP</i> Gene Family and Its Expression Profile Identifies Potential Key Candidate Genes Involved in Abiotic Stress Responses
Published 2025-03-01“…Promoter analysis identified diverse <i>cis</i>-acting elements in <i>BpTCP</i>, suggesting that they play a role in stress responses, hormonal regulation, and plant growth and development. qRT-PCR analysis showed that <i>BpTCP</i> genes displayed tissue-specific expression patterns in the roots, stems, and leaves, displaying remarkable differences in expression levels when subjected to abiotic stresses, including drought and high- and low-temperature conditions. …”
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1245
Addressing Shortcomings in Contingency Standards of Care
Published 2022-09-01“…Although the transition from contingency standards to crisis standards is defined by the inability to provide functionally equivalent care, the difference in practice may merely be a distinction between visible, immediate sacrifices to patient well-being during crises and less-obvious, long-term decrements in community health due to protracted contingency care alterations. …”
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1247
Quantum <i>κ</i>-Entropy: A Quantum Computational Approach
Published 2025-04-01“…Various alternative expressions stemming from its definition emphasizing computational and algorithmic aspects are worked out: First, for the case of canonical Gibbs states, it is shown that <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mi>κ</mi></semantics></math></inline-formula>-entropy is cast in the form of an expectation value for an observable that is determined. …”
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1248
Random Finite Element Analysis and Random Factor response Mechanism for Geocell-reinforced Soil Retaining Walls
Published 2025-01-01“…Further, by comparing the stress cloud maps of the deterministic model and the random field model, it is found that the deterministic model presents regular stress gradients and smooth contour transitions, while the random field model exhibits significant irregular stress distribution characteristics. This difference stems from the use of the centroid discretization method to process the cell parameters, which makes each cell have unique mechanical properties, thus reflecting the spatial variability of geotechnical materials more realistically. …”
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