Structural information in therapeutic peptides: Emerging applications in biomedicine by Valentín Iglesias, Oriol Bárcenas, Carlos Pintado‐Grima, Michał Burdukiewicz, Salvador Ventura

“…Peptides are attracting a growing interest as therapeutic agents. This trend stems from their cost‐effectiveness and reduced immunogenicity, compared to antibodies or recombinant proteins, but also from their ability to dock and interfere with large protein–protein interaction surfaces, and their higher specificity and better biocompatibility relative to organic molecules. …”
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Pomalidomide in relapsed and refractory multiple myeloma: multicenter retrospective study by V. G. Potapenko, E. V. Baumert, A. A. Bobrova, R. V. Vashchenkov, N. V. Dorofeeva, K. D. Kaplanov, E. V. Karyagina, A. N. Levanov, A. S. Luchinin, S. I. Moiseev, A. V. Novitskii, A. S. Nizamutdinova, О. V. Pirogova, S. A. Povzun, М. V. Platonov, V. V. Porunova, D. А. Ptashnikov, V. V. Ryabchikova, S. Ya. Simeniv, I. А. Skorokhod, Е. А. Ukrainchenko, D. А. Chaginskaya, T. V. Shelekhova, M. N. Shirokova, A. A. Shutylev, N. V. Medvedeva

“…Kidney impairment at the onset was in 10 (15 %) patients, the normal function was in 57 (85 %) patients and 4 patients had no data. …”
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Integrated Multiomics Analyses of the Molecular Landscape of Sarcopenia in Alcohol‐Related Liver Disease by Nicole Welch, Pugazhendhi Kannan, Saurabh Mishra, Annette Bellar, Vandana Agrawal, Grahame Kidd, Emily Benson, Ryan Musich, Raya Tabbalat, Ling Li, J. Mark Brown, Belinda Willard, Karyn A. Esser, Laura E. Nagy, Srinivasan Dasarathy

“…Studies were done in a comprehensive array of models including ethanol‐treated (ET) murine and human‐induced pluripotent stem cell–derived myotubes (hiPSCm), skeletal muscle from a mouse model of ALD (mALD) and human patients with alcohol‐related cirrhosis and controls. …”
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Comprehensive genome-wide identification and expression analysis of the EPF/EPFL gene family in oat by Qingxue Jiang, Lin Ma, Siyuan Guo, Xinyue Zhou, Zhipeng Zhang, Yanhong Cui, Jun Tang, Dengxia Yi, Xuemin Wang

“…Expression profiling revealed distinct tissue-specific patterns: preferential expression in roots (12 genes), stems (6 genes), leaves (5 genes), and spikes (7 genes), with 3 genes showing dual peak expression in stems and leaves. …”
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Pilgrims’ Cultural Contacts on Their Journey to the Hijaz from Bukhara in the 19th Century by Mustafa Tanrıverdi

“…Despite the presence of different routes for the long pilgrimage, reaching the Hijaz by way of Istanbul was a priority for Turkestani pilgrims. …”
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Choice of props for courtship dancing in estrildid finches by Masayo Soma, Misaki Nakatani, Nao Ota

“…Abstract Among the diverse sexual signals used by birds, the possible signaling functions of non-bodily objects during mating/courting displays remain unexplained. …”
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MSPB-YOLO: High-Precision Detection Algorithm of Multi-Site Pepper Blight Disease Based on Improved YOLOv8 by Xiaodong Zheng, Zichun Shao, Yile Chen, Hui Zeng, Junming Chen

“…In response to the challenges of low accuracy in traditional pepper blight identification under natural complex conditions, particularly in detecting subtle infections on early-stage leaves, stems, and fruits. This study proposes a multi-site pepper blight disease image recognition algorithm based on YOLOv8, named MSPB-YOLO. …”
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CMYB1 Encoding a MYB Transcriptional Activator Is Involved in Abiotic Stress and Circadian Rhythm in Rice by Min Duan, Peng Huang, Xi Yuan, Hui Chen, Ji Huang, Hongsheng Zhang

“…Tissue-specific gene expression analysis revealed that CMYB1 was highly expressed in rice stems and nodes. qRT-PCR assay indicated that CMYB1 was dramatically induced by cold stress (>100-folds) and induced by exogenous ABA and osmotic stress. …”
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Comprehensive pan-cancer analysis of PPP1R3G reveals its diagnostic, prognostic, and immunotherapeutic implications by Nie Zhang, Jiaoyu Li, Yanzhi Ren, Yahui Xu

“…Moreover, PPP1R3G was significantly linked to immune checkpoints, immunomodulators, prognosis, immunoregulatory genes, tumor stemness, cellular function, and immune infiltration across numerous cancer types. …”
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Food manipulation and processing in wild western gorillas of Central African Republic: implications for studying behavioural variability by Shelly Masi, Ellen JM Meulman, Françoise Aubaile, Sabrina Krief, Angelique Todd, Emanuelle Pouydebat

“…Frame by frame video analysis (31 hours; 10 months during 2008–2009) of a habituated group (Number of individuals = 13) of western gorillas at Bai Hokou, Central African Republic, was used to investigate, food-manipulation strategies for different food types (e.g. leaves, stems, fruits), for the first time in this species. …”
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Genome-Wide identification and expression profiles of the WRKY transcription factor family in Artocarpus nanchuanensis by Xiao Zhang, Changying Xia, Shiqi You, Yunli Chen, Youwei Zuo, Huan Zhang, Wenqiao Li, Zhe Zhang, Hongping Deng

“…Furthermore, the expression profiles of AnWRKYs in roots, stems, and leaves showed that AnWRKYs had different spatial expression patterns. …”
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Genome-wide investigation of cytokinin oxidase/dehydrogenase (CKX) family genes in Brassica juncea with an emphasis on yield-influencing CKX by Balaji Balamurugan, Mansi Singh, Dwijesh C. Mishra, Sandhya Sharma, Kishor Gaikwad, Ganapati Mukri, Mahesh Rao, Navin C. Gupta

“…Expression pattern analysis by RT-qPCR in the high-and low-yielding B. juncea cultivars showed that all 24 CKX expressed differentially in various tissues; most were expressed in leaves, stems and developing siliques. The two functional domains, FAD-binding and Cytokinin-binding domains required for CKX activity, were conserved across the CKX family genes. …”
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Design and experiment of key components of a insertion vegetable grafting machine with six plants synchronous by Yongtao Yu, Yanjun Li, Fuxiang Xie, Jian Song, Yang Bai, Yu Fan

“…Based on the heterogeneous operation requirements of rootstock and scion, a six plant synchronous insertion vegetable grafting machine was innovatively designed, which integrates flexible clamping, dynamic cutting, and precise docking functions. The rectangular hand claw is embedded with EVA flexible material (maximum clamping pressure of the clamping mechanism: rootstock 266.35 Pa and scion 158.92 Pa), to overcome the fragile seedling damage control problems; Optimization of rootstock dynamics modeling with the V-shaped gathering block opening angle of 90° to achieve adaptive positioning of heterogeneous stems; The dual cutting system of positive-cutting and rotary-cutting matches the different cutting requirements of rootstock and scion. …”
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Effects of Heteroaromatic Thiol Additives on Co Electrodeposition by Surface Adsorption by Yu Duan, Yedi Li, Tingjun Wu, Wei Xu, Lei Zhu, Qiang Liu, Yiying Wang, Wenjie Yu

“…Cyclic voltammetry, chronopotentiometry, quantum chemical calculations, and characterization tests were employed to investigate the adsorption behavior of additive molecules with different functional groups on cobalt. The results indicate that the inhibitory strength of the three additives on electrodeposition follows the following order: MBI > MBIS > MBO. …”
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Emergence Rate and N Metabolism Assessment of Herbaceous Cotton (Gossypium hirsutum l.r. latifolium Hutch) in Soil with High Boron Concentrations by Roberta Possas de Souza, Maycon Anderson de Araujo, Tássia Caroline Ferreira, Beatriz Silvério dos Santos, Isabella Fiorini de Carvalho, Bruno Bonadio Cozin, Liliane Santos de Camargos

“…Abstract Plants need boron (B) in low concentrations to carry out structural and metabolic functions. However, excess B in the soil can cause problems in plant emergence and development. …”
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Deciphering cholangiocarcinoma heterogeneity and specific progenitor cell niche of extrahepatic cholangiocarcinoma at single-cell resolution by Chunliang Liu, Xiang Wang, Erdong Liu, Yali Zong, Wenlong Yu, Youhai Jiang, Jianan Chen, Mingye Gu, Zhengyuan Meng, Jingfeng Li, Yang Liu, Yongjie Zhang, Jing Tang, Hongyang Wang, Jing Fu

“…This subpopulation was closely associated with an interferon-stimulated gene 15 (ISG15)-enriched mesenchymal and immune microenvironment. Functional assays demonstrated that ISG15 stimulation significantly boosted stemness, basal-like features, and drug resistance in eCCA cells, highlighting its pivotal role in sustaining the LY6D + progenitor niches. …”
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Decoupled dynamics of absolute and relative lymphocyte counts and age−polarized CD4+/CD8+ ratio in infants versus older adults by Ting Ge, Ting Ge, Ting Ge, Guixin He, Guixin He, Guixin He, Qian Cui, Qian Cui, Qian Cui, Shuangcui Wang, Shuangcui Wang, Shuangcui Wang, Zekun Wang, Yingying Xie, Yingying Xie, Yingying Xie, Yuanyuan Tian, Yuanyuan Tian, Yuanyuan Tian, Juyue Zhou, Juyue Zhou, Juyue Zhou, Wentao Li, Wentao Li, Baohui Wang, Keming Zhang, Jianchun Yu, Jianchun Yu

“…BackgroundSignificant phenotypic and functional differences in peripheral lymphocyte subsets between infants and the elderly contribute to age-related variations in disease susceptibility and clinical outcomes. …”
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A parameter adaptive EEFO VMD method to mitigate noise and trend interference of blast vibration signals by Zhenyang Xu, Zuofu Zhang, Fuqiang Ren, Xuesong Wang, Aobo Liu, Lianjun Guo

“…Abstract Blasting vibration signals are often contaminated by trend terms and noise, stemming from environments, and instrument errors. …”
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Indigenous bacterial studies of local lettuce and its application to commercial lettuce cultivation in hydroponic systems by Unun Triasih, Abdul Latief Abadi, Luqman Qurata Aini, Mintarto Martosudiro, Farida Yulianti, Saptini Mukti Rahajeng, Nur Hayati Hadiba, Titiek Yulianti, Dita Agisimanto

“…ABSTRACT Plants naturally utilize associated microbes to perform a variety of beneficial functions, including nutrient acquisition. Identifying a consortia of different beneficial microbes that live in harmony with a native ecosystem or living plant is necessary for application in agriculture. …”
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Genome-wide identification and gene expression pattern analysis of the carotenoid cleavage oxygenase gene family in Fagopyrum tataricum by Huan Li, Xin Yao, Ailing He, Guoxing Xue, Haizhu Yang, Yu Fan, Sanwei Yang, Jingjun Ruan

“…Summary In this study, the FtCCO family genes of Tartary buckwheat were identified at the genome-wide level, and the gene expression pattern of the FtCCO gene family in different tissues or treatments was determined. This study provides a theoretical basis for further analysis of the functions of theFtCCO family, which is of great significance for the mining of resistance genes and trait improvement.…”
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