Characterisation and germline transmission of cultured avian primordial germ cells. by Joni Macdonald, James D Glover, Lorna Taylor, Helen M Sang, Michael J McGrew

“…In male hosts, cultured PGCs form functional gametes as demonstrated by the generation of viable offspring.…”
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miRNA-182-5p promotes myogenic differentiation of C2C12 cells via the suppression of ZBTB7A by Mengyuan Zhang, Yongheng Wang, Shan Shan, Siyu Liu

“…IntroductionSkeletal muscle possesses a significant regenerative capacity, which is largely mediated by myogenic satellite stem cells. MicroRNAs are known regulators of muscle development. miR-182-5p plays important roles in cell proliferation and migration in various cell types and pathologies. …”
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Mathematical reconstruction of the metabolic network in an in-vitro multiple myeloma model. by Elias Vera-Siguenza, Cristina Escribano-Gonzalez, Irene Serrano-Gonzalo, Kattri-Liis Eskla, Fabian Spill, Daniel Tennant

“…This study employs an interdisciplinary approach that leverages the predictive power of mathematical modelling to enrich experimental findings. We develop a functional multicellular in-silico model that facilitates the qualitative and quantitative analysis of the metabolic network spawned by an in-vitro co-culture model of bone marrow mesenchymal stem- and myeloma cell lines. …”
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The zebrafish moonshine gene encodes transcriptional intermediary factor 1gamma, an essential regulator of hematopoiesis. by David G Ransom, Nathan Bahary, Knut Niss, David Traver, Caroline Burns, Nikolaus S Trede, Noelle Paffett-Lugassy, Walter J Saganic, C Anthoney Lim, Candace Hersey, Yi Zhou, Bruce A Barut, Shuo Lin, Paul D Kingsley, James Palis, Stuart H Orkin, Leonard I Zon

“…Surprisingly, a high level of zygotic tif1gamma mRNA expression delineates ventral mesoderm during hematopoietic stem cell and progenitor formation prior to gata1 expression. …”
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Passion fruit plants alter the soil microbial community with continuous cropping and improve plant disease resistance by recruiting beneficial microorganisms. by Ye Wang, Yao Teng, Jianli Zhang, Zixiong Zhang, Chen Wang, Xiukun Wu, Xiuqin Long

“…In addition, during the continuous cropping, grafting different scions in the same rootstock contributed to the aggregation of differential rhizosphere microbial communities. …”
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Identification of metal tolerance proteins (MTP) and their gene expression under drought stress in potato (Solanum tuberosum L.) by Zahra HAJIBARAT, Abbas SAIDI

“…Expression profile analysis revealed that the StMTP9 were up-regulated in leaves and stem, while, StMTP8 up-regulated in leaves. Both genes down-regulated in tubers, roots as well as under drought stress. …”
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Context-dependent autophagy in cancer: deciphering cytoprotective vs. cytotoxic roles and therapeutic modulation strategies by Samer Osama Kostandy, Salwa Aburageh Abuiessa, Mai Mostafa Helmy, Maged Wasfy Helmy

“…The review also examines the role of autophagy in cancer stem cells, metastasis, and therapy resistance, providing insights into how autophagy modulation can enhance chemotherapy, radiotherapy, and immunotherapy. …”
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Effects of Rock Fragment Cover on the Sediment Transport Capacity of Overland Flow by Lixia Dong, Suhua Fu, Baoyuan Liu

“…Tc typically follows a power function with slope gradient (S) and flow discharge (q) under bare flumes, but varying exponents complicate practical application. …”
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Considerations on non-ketotic hyperglycinemia in 21st century by V. M. Studenikin

“…To conclude the article, some considerations on the prognosis for different clinical variants of non-ketotic hyperglycinemia in pediatric patients are provided.…”
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Single‐cell polyadenylation site mapping reveals 3′ isoform choice variability by Lars Velten, Simon Anders, Aleksandra Pekowska, Aino I Järvelin, Wolfgang Huber, Vicent Pelechano, Lars M Steinmetz

“…Here, we perform genome‐wide quantification of polyadenylation site usage in single mouse embryonic and neural stem cells using a novel single‐cell transcriptomic method, BATSeq. …”
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Identification and characterization of early human photoreceptor states and cell-state-specific retinoblastoma-related features by Dominic WH Shayler, Kevin Stachelek, Linda Cambier, Sunhye Lee, Jinlun Bai, Bhavana Bhat, Mark W Reid, Daniel J Weisenberger, Jennifer G Aparicio, Yeha Kim, Mitali Singh, Maxwell Bay, Matthew E Thornton, Eamon K Doyle, Zachary Fouladian, Stephan G Erberich, Brendan H Grubbs, Michael A Bonaguidi, Cheryl Mae Craft, Hardeep P Singh, David Cobrinik

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Comparative systems biology of human and mouse as a tool to guide the modeling of human placental pathology by Brian Cox, Max Kotlyar, Andreas I Evangelou, Vladimir Ignatchenko, Alex Ignatchenko, Kathie Whiteley, Igor Jurisica, S Lee Adamson, Janet Rossant, Thomas Kislinger

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Extracellular Vesicles in the Cornea: Insights from Other Tissues by Tina B. McKay, Vincent Yeung, Audrey E. K. Hutcheon, Xiaoqing Guo, James D. Zieske, Joseph B. Ciolino

“…We focus on EV-matrix interactions, potential functions during corneal wound healing, and the bioactivity of mesenchymal stem cell-derived EVs. …”
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Profound downregulation of neural transcription factor Npas4 and Nr4a family in fetal mice neurons infected with Zika virus. by Sergio P Alpuche-Lazcano, James Saliba, Vivian V Costa, Gabriel H Campolina-Silva, Fernanda M Marim, Lucas S Ribeiro, Volker Blank, Andrew J Mouland, Mauro M Teixeira, Anne Gatignol

“…To date, ZIKV mechanism of infection and pathogenesis is not entirely understood and different studies on gene regulation of ZIKV-infected cells have identified a dysregulation of inflammatory and stem cell maintenance pathways. …”
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Impact of Surface Cover Types and Coverage on Hydraulic Parameters of Overland Flow by Kai Zhang, Ning Li, Suhua Fu, Dike Feng

“…The specific experimental conditions were as follows: one slope gradient (15°) and one flow discharge (1.0 × 10−3 m3 s−1), four cover types (corn residue, rock fragment, sweet potato, and corn stem), and seven coverage percentages ranging from 0% to 70%. …”
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Distinct characteristics of brain metastasis in lung adenocarcinoma: development of high-confidence cell lines by Jintao He, Zen-ichi Tanei, Dao-Sian Wu, Lei Wang, Yoshitaka Oda, Masumi Tsuda, Shinya Tanaka

“…Through RNA sequencing and bioinformatics analyses, we identified transcriptomic differences among these cell lines, revealing that H1975-BM1 cells primarily exhibit stem cell function and migration characteristics, while H1975-BM3 cells display enhanced chemotaxis, cell adhesion, and cytokine secretion associated with interactions. …”
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CD44 signaling in skin wound healing and regeneration by Annie Y. Guan, Yanlin Chen, Scheffer C. Tseng, Qing Lin

“…Importantly, CD44 signaling initiated by ligands may differently regulate the phenotypic and functional plasticity of various immune cells in wound inflammation. …”
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PD-1 blockade employed at the time CD8+ T cells are activated enhances their antitumor efficacy by Douglas G McNeel, Donghwan Jeon, Ichwaku Rastogi, Jena E Moseman

“…In the present study, we sought to determine whether, and by what mechanisms, the timing of PD-1 blockade with respect to vaccination affects antitumor T cell function.Methods TRAMP-C1 or E.G7-OVA tumor-bearing mice received PD-1 blockade at different timing intervals with a tumor-associated antigen vaccine. …”
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Determination of Trace Elements in Corydalis conspersa and Corydalis linarioides by ICP-AES by Qing Du, Yanguo Cai, Zhi Chen, Dongliang Wei, Yande Cao, Ying Chen, Shulin Yu, Qianqian Zhao, Jiang Wu, Mingdi Liu

“…We can know that the contents of Al, Ca, Fe, K, Mg, Na, and P in roots, stems, leaves, and flowers were higher. The contents of elements in different tissues and areas were as follows: flower > leaf > stem > root, Zeku County > Guide County > Nangqian County > Henan County. …”
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MTFAP: a comprehensive platform for predicting and analyzing master transcription factors by Jianyuan Zhou, Haojie Yu, Chunhui Lou, Min Yang, Yanshang Li, Qian Yang, Shuhan Li, Chunwang Ji, Song Li, Shuang Wang, Haotian Cao, Xuecang Li, Lian Liu

“…MTFAP is a comprehensive web tool designed to predict and analyze MTFs with different data types. To enhance user experience and facilitate exploration of interest MTFs, MTFAP offers search and browse functionalities. …”
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