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Severe Hypofunction of Allogeneic Hematopoietic Stem Cell Transplant in Patients with Oncohematological Diseases: Incidence, Risk Factors, and Outcomes
Published 2019-05-01“…Based on strict criteria, to assess incidence, pretransplantation risk factors, and outcomes of severe hypofunction of graft, i.e. poor graft function (sPGF), following allogeneic hematopoietic stem cell transplantation (allo-HSCT) in adults. …”
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Cryopreservation of Hematopoietic Stem Cells for Pediatric Autologous Stem Cell Transplantation
Published 2024-11-01“…Background and Objectives: Dimethylsulfoxide(DMSO) is gold standard for cryopreservation of hematopoietic progenitor cells (HPC) to reconstitute hematopoiesis in autologous stem cell transplants (auto-HSCT). Higher DMSO-related adverse effects (AEs) are reported in pediatric patients due to lower body weight with the recommended maximal dose of 1g/kg bodyweight. …”
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Comparison of Stromal Vascular Fraction and Adipose-Derived Stem Cells for Protection of Renal Function in a Rodent Model of Ischemic Acute Kidney Injury
Published 2022-01-01“…We compared the abilities of stromal vascular fraction (SVF) and adipose-derived stem cells (ADSC), injected via three different routes, to protect renal function in a rodent model of ischemic AKI. …”
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Transcriptomic analysis of neural stem and progenitor cells in comparison with glioblastoma stem cells
Published 2023-12-01“…It is believed that GSCs can be formed as a result of oncogenic transformation of neural stem and progenitor cells (NSPcs), which have morphological and functional properties similar to them. …”
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Experimental study of partially oxidized sodium alginate gel combined with myogenic stem cells to improve cardiac function in aged rats with myocardial infarction
Published 2025-01-01“…[Methods] The models of myocardial infarction in aged rats were established by ligating the coronary arteries and divided randomly into the group of saline control group, sodium alginate group, myogenic stem cells group and sodium alginate combined with myogenic stem cells group(joint group), each had 30 rats.The same amount of corresponding material was injected into the myocardial infarction area of rats in each group respectively.The cardiac structure and function of the rats were evaluated by echocardiography 8 weeks after the operation, and then the rats were executed.The hearts were removed to observe the differences in ventricular remodeling by histological analysis and the angiogenesis and collagen secretion of the ventricular slices were further analyzed. …”
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Cancer stem cells: The potential role of autophagy, proteolysis, and cathepsins in glioblastoma stem cells
Published 2017-03-01“…In case of immune recognition, several survival mechanisms including, regulation of autophagy, proteases, and cell surface major histocompatibility complex class I molecules, are found in glioblastoma stem cells. In different pathways, cathepsins play a crucial role in processing functional proteins that are necessary for several processes and proper cell function. …”
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The immunology of corneal limbal stem cells: the up-to-date approach to stem cell transplantation
Published 2023-09-01“…There are different types of stem cell grafting including cultivated limbal epithelial transplantation (CET) and simple limbal epithelial transplantation (SLET). …”
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Adipose-derived mesenchymal stem cell-supported ciprofloxacin therapy effectively protects the kidney parenchyma and functional integrity against acute pyelonephritis damage in rod...
Published 2025-06-01“…This study revealed that adipose-derived mesenchymal stem cell-facilitated ciprofloxacin therapy effectively protected the kidney parenchyma and functional integrity against acute pyelonephritis damage in rodents. …”
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Comparative Analysis of Short-Term and Long-Term Clinical Efficacy of Mesenchymal Stem Cells from Different Sources in Knee Osteoarthritis: A Network Meta-Analysis
Published 2024-01-01“…A meta-analysis revealed that different sources of MSCs improved knee function and pain more effectively among patients suffering from knee OA (KOA) than controls. …”
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CACNA1A loss-of-function affects neurogenesis in human iPSC-derived neural models
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Mesenchymal stem cells: diversity
Published 2023-04-01“…However, some cells at different stages of histogenesis leave it. Such resident cells in tissues are stem cells. …”
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Prepatterning in the stem cell compartment.
Published 2010-05-01“…Our results suggest that pluripotent NTERA2 stem cells oscillate between functionally distinct substates that are primed to select distinct lineages when differentiation is induced.…”
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Tenogenic Cues Are Biochemically and Environmentally Distinct for Tendon Stem Cells and Mesenchymal/Stromal Stem Cells
Published 2025-01-01“…Tendons’ inherent limited regenerative capacity often hinders complete recovery from injuries, leading to chronic conditions and impaired functionality. Autologous mesenchymal/stromal stem cells (MSCs) and tendon-derived stem cells (TSCs), combined with growth factors (GFs) like GDF-5, GDF-6 and GDF-7, are emerging as potential therapies for tendinopathy. …”
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Clinical impacts of total parenteral nutrition in hematopoietic stem cell transplantation patients with high nutritional risk
Published 2024-12-01“…In addition, there were no significant differences in CRBSI incidence or liver function between the non-TPN and TPN groups. …”
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Comprehensive Evaluation of Different Oat Varieties in Semi-Arid Areas of Gansu Province
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Differences in neuronal ciliation rate and ciliary content revealed by systematic imaging-based analysis of hiPSC-derived models across protocols
Published 2025-04-01“…Patient derived- or genetically engineered human induced pluripotent stem cells (hiPSCs) are therefore a precious resource for investigating the role of cilia in human neurons.MethodsIn this study we used a variety of 2D and 3D neuronal differentiation protocols in multiple hiPSC lines and systematically analyzed ciliation rates and ciliary length in hiPSCs, neural stem cells (NSCs), immature and different types of mature neurons using immunofluorescence.ResultsWe found that ciliation rate varied substantially between cell lines and differentiation protocols. …”
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Machine learning-based characterization of stemness features and construction of a stemness subtype classifier for bladder cancer
Published 2025-04-01“…We calculated the mRNA expression-based stemness index (mRNAsi) using the OCLR algorithm. We compared the differences in overall survival, genomic characteristics, tumor microenvironment, and treatment response between the stemness subtypes. …”
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