Multiple white matter volume reductions in patients with panic disorder: relationships between orbitofrontal Gyrus volume and symptom severity and social dysfunction. by Jun Konishi, Takeshi Asami, Fumi Hayano, Asuka Yoshimi, Shunsuke Hayasaka, Hiroshi Fukushima, Thomas J Whitford, Tomio Inoue, Yoshio Hirayasu

“…A voxel-based morphometry study was conducted to evaluate differences in regional white matter volume between 40 patients with PD and 40 healthy control subjects (HC). …”
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Natural and engineered extracellular vesicles in vascular diseases: a focus on therapeutic effects, challenges and prospective by Mahdi Ahmadi, Reza Abbasi, Rana Keyhanmanesh, Razieh Momen Mesgin, Nima Abdyazdani, Maryam Shoaran, Jafar Rezaie

“…The term EVs refers to the heterogeneous population of vesicles, such as exosomes and microvesicles that participate in cell communication during VD. EVs from different cells, especially those of stem cells, show great promise in the improvement of various VD. …”
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Production of platelets <i>in vitro</i> in functionalised 3-dimensional scaffolds mimicking the bone marrow niche by Holly R. Foster, Maria Colzani, Guenaelle Bouet, Daniel Howard, Christian A. Di Buduo, Nicole Müller-Sienerth, Amie K. Waller, Yi Sun, Natalia Davidenko, Jennifer H. Shepherd, Thomas Moreau, Amanda L. Evans, Paolo M. Soprano, Martin E.M. Parsons, Yumi Ying Sims, Meera Arumugam, Wardiya Afshar-Saber, Ernest Turro, Patricia B. Maguire, Serena M. Best, Ruth E. Cameron, Alessandra Balduini, Gavin J. Wright, Cedric Ghevaert

“…Using two different methodologies, we functionalise either collagen- or silkbased 3-dimensional scaffolds and confirm increased functional platelet production by up to two-fold. …”
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Preliminary study on the time-correlation changes in brain neurotransmitters of mice exposed to mushroom toxin ibotenic acid by Ruanxian Dai, Ruanxian Dai, Zhantao Duan, Bin Han, Guobing Chen, Fuping Wang, Zhuange Shi, Xian Zhou, Haifei Song, Li Ma, Qiang Meng

“…Ibotenic acid is identified as the primary neurotoxin associated with this form of poisoning; however, the underlying mechanisms of its neurotoxicity remain poorly understood.ObjectiveThis study aims to systematically evaluate the effects of ibotenic acid exposure across three consecutive key time points, from intoxication to recovery, on neurotransmitters related to the GABA/Glutamic-Acid, dopaminergic, serotonergic, and cholinergic systems in five brain regions: the cerebral cortex, hippocampus, striatum, brain stem, and cerebellum.MethodsThrough behavioral tests, we assessed the effects of ibotenic acid exposure on voluntary activities and learning and memory functions in mice. …”
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Separation and Identification of Terpenoids in Three Pineapple Fibers Using Ultra-High Performance Liquid Chromatography-Tandem Mass Spectrometry by Yijun Liu, Yuliang Chen, Jiameng Liu, Lin Zhu, Lijing Lin, Zhikai Zhuang, Jiangxiu He, Tao Li, Gang Chen, Siru Yao

“…The research results showed that there were 9, 8 and 7 significantly different terpenoid compounds in pineapple leaf fiber and pineapple stem fiber, pineapple leaf fiber and pineapple root fiber, and pineapple stem fiber and pineapple root fiber respectively. …”
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The dual GLP-1 and GIP receptor agonist tirzapetide provides an unintended interaction with the β-adrenoceptors and plays a role in glucose metabolism in hyperglycemic or senescent... by Dunya Aydos, Zeynep Busra Aksoy, Mehmet Altay Unal, Kamil Can Akcali, Ceylan Verda Bitirim, Belma Turan

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The impact of LLM chatbots on learning outcomes in advanced driver assistance systems education by Mohsin Murtaza, Chi-Tsun Cheng, Bader M. Albahlal, Muhana Magboul Ali Muslam, Mansoor Syed Raza

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Expression of auxin transporter genes in flax (<i>Linum usitatissimum</i>) fibers during gravity response by N. N. Ibragimova, N. E. Mokshina

“…Earlier, we described significant morphological changes in phloem fibers with a thickened cell wall located on different sides of the stem in the area of the gravitropic curvature. …”
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Clinical implications, safety, efficacy of Recombinant Human Granulocyte Colony-Stimulating Factors and Pegylated Equivalent by Silvia Bolis, Emilia Cocorocchio, Consuelo Corti, Andrés J M Ferreri, Niccolò Frungillo, Giovanni Grillo, Emanuela Salè Omodeo, Lucilla Tedeschi, Vittorio Ruggero Zilioli

“…</p><p>On this background, we reviewed available evidence in order to analyze the impact of these chemical and pharmacodynamic differences among G-CSF molecules on safety, particularly in healthy peripheral-blood stem-cells donors, functional qualities of inducted neutrophils, and mobilization of hematopoietic stem cells. …”
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Decoding pilocarpine biosynthesis and its roles in Pilocarpus microphyllus through a comparative transcriptomics approach by Mariane Brom Sobreiro, Giordano Bruno Soares-Souza, Leandro Magalhães, Débora de Morais Cordeiro, Michele Molina, Santelmo Vasconcelos, Yan Nunes Dias, Renato R. Moreira-Oliveira, Markus Gastauer, Silvio Ramos, Guilherme Oliveira, Cecílio Frois Caldeira, Amanda F. Vidal

“…This study presents the first comparative transcriptomic analysis in jaborandi by investigating gene expression across four different tissues (leaflets, rachis, root, and stem) and exploring potential pathways and functions involved in pilocarpine biosynthesis. …”
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Transcriptomic analysis supports a role for the nervous system in regulating growth and development of Fasciola hepatica juveniles. by Emily Robb, Erin M McCammick, Duncan Wells, Paul McVeigh, Erica Gardiner, Rebecca Armstrong, Paul McCusker, Angela Mousley, Nathan Clarke, Nikki J Marks, Aaron G Maule

“…These phenotypic differences were consistent with the upregulation of neoblast-like stem cell and cell-cycle associated genes in in vivo maintained worms. …”
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An automated platform for simultaneous, longitudinal analysis of engineered neuromuscular tissues for applications in neurotoxin potency testing by Jacob W. Fleming, Molly C. McCloskey, Kevin Gray, David R. Nash, Vincent Leung, Christos Michas, Shawn M. Luttrell, Christopher Cavanaugh, Julie Mathieu, Shawn Mcguire, Mark Bothwell, David L. Mack, Nicholas A. Geisse, Alec S.T. Smith

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Exhaled breath particles as a diagnostic tool for bronchiolitis obliterans syndrome in lung transplant recipients: a longitudinal study by Runchuan Gu, Runchuan Gu, Runchuan Gu, Embla Bodén, Embla Bodén, Embla Bodén, Embla Bodén, Sandra Lindstedt, Sandra Lindstedt, Sandra Lindstedt, Sandra Lindstedt, Franziska Olm, Franziska Olm, Franziska Olm, Franziska Olm

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Suppressing the Aging Phenotype of Mesenchymal Stromal Cells: Are We Ready for Clinical Translation? by Ilaria Roato, Matteo Visca, Federico Mussano

“…Here, the authors reviewed the most updated literature on the potential causes of senescence, with a particular emphasis on the current and future therapeutic approaches aimed at reverting senescence and/or extending the functional lifespan of stem cells.…”
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Gold Nanoparticle Adsorption and Uptake are Directed by Particle Capping Agent by Rashad Kariuki, Rowan Penman, Alexander D. Newbold, Kalpani A. Mirihana, Pierre H. A. Vaillant, Tilly P. Shepherd, Nastaran Meftahi, Gary Bryant, Kislon Voïtchovsky, Claudia Contini, Andrew Hung, Kevion K. Darmawan, Charlotte E. Conn, Saffron J. Bryant, Andrew J. Christofferson, Aaron Elbourne

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Neural propensity for trait rumination in adolescents: A cross-sectional study with Voxel-Based Morphometry by Diane Joss, Anna O. Tierney, Kristina Pidvirny, Nigel M. Jaffe, Hannah Goodman, Nicholas J. Carson, Zev Schuman-Olivier, Christian A. Webb

“…While most of the findings are consistent with prior research on adult depression and rumination, some discrepancies may stem from differences in age and psychopathology severity across study samples. …”
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Tokay gecko tail regeneration involves temporally collinear expression of HOXC genes and early expression of satellite cell markers by Luthfi Nurhidayat, Vladimir Benes, Sira Blom, Inês Gomes, Nisrina Firdausi, Merijn A. G. de Bakker, Herman P. Spaink, Michael K. Richardson

“…Abstract Background Regeneration is the replacement of lost or damaged tissue with a functional copy. In axolotls and zebrafish, regeneration involves stem cells produced by de-differentiation. …”
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Imaging Reporters for Proteasome Activity Identify Tumor- and Metastasis-Initiating Cells by Amanda C. Stacer, Hanxiao Wang, Joseph Fenner, Joseph S. Dosch, Anna Salomonnson, Kathryn E. Luker, Gary D. Luker, Alnawaz Rehemtulla, Brian D. Ross

“…These studies support proteasome function as a tool to investigate tumor- and metastasis-initiating cancer cells and a potential biomarker for outcomes in patients with several different cancers.…”
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Development and studies on LEAFY genetic transformation system with high efficiency in commercial grape (Vitis vinifera L. var muscat) by CHEN Li-geng, LIU Shu-fang, HU Xi-qin

“…Transgenic plants appear to be a new way to grape improvement and a powerful tool for studying gene functions. Using a direct high frequency shoot regeneration system suitable for genetic transformation was established successfully in this study, which was the base for the following research of construction of a direct high frequency shoot regeneration system suitable for genetic transformation was established successfully by using pieces of fresh stem of Muscat of Alexandria (Vitis vinifera L. var. muscat) as explants, and transformed plants were obtained with a higher transformation efficiency. …”
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Semantic Segmentation Method for High-Resolution Tomato Seedling Point Clouds Based on Sparse Convolution by Shizhao Li, Zhichao Yan, Boxiang Ma, Shaoru Guo, Hongxia Song

“…Semantic segmentation of three-dimensional (3D) plant point clouds at the stem-leaf level is foundational and indispensable for high-throughput tomato phenotyping systems. …”
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