Advances in MicroRNA-Mediated Reprogramming Technology by Chih-Hao Kuo, Shao-Yao Ying

“…Soon after the discovery of embryonic-stem-cell- (ESC-) specific miRNAs, researchers began to investigate their functions in embryonic development and differentiation, as well as their potential roles in somatic cell reprogramming (SCR). …”
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Vessel Wall-Derived Mesenchymal Stromal Cells Share Similar Differentiation Potential and Immunomodulatory Properties with Bone Marrow-Derived Stromal Cells by Zoltán Veréb, Anett Mázló, Attila Szabó, Szilárd Póliska, Attila Kiss, Krisztina Litauszky, Gábor Koncz, Zoltán Boda, Éva Rajnavölgyi, Attila Bácsi

“…For comparative analysis, the expression of different stemness, proliferation, and differentiation-related genes was determined by Affymetrix gene array. …”
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Extracellular Vesicles from MSC Modulate the Immune Response to Renal Allografts in a MHC Disparate Rat Model by M. Koch, A. Lemke, C. Lange

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Exosomes for Intramyocardial Intercellular Communication by Elisabetta Cervio, Lucio Barile, Tiziano Moccetti, Giuseppe Vassalli

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Generation of hiPSC lines with fusion tagged thyroid hormone receptor α isoforms to study isoform-specific actions of TRα1 and TRα2 by Nina Härting, Katarzyna A. Ludwik, Regina Jahn, Frank J. Kaiser, Harald Stachelscheid

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Role of Primary Cilia in Skeletal Disorders by Xinhua Li, Song Guo, Yang Su, Jiawei Lu, Donghua Hang, Shao Cao, Qiang Fu, Ziqing Li

“…In addition, the intact of primary cilium is essential to osteogenic/chondrogenic induction of mesenchymal stem cells, regarded as a promising target for clinical intervention for skeletal disorders. …”
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Endothelial Plasticity: Shifting Phenotypes through Force Feedback by Guido Krenning, Valerio G. Barauna, José E. Krieger, Martin C. Harmsen, Jan-Renier A. J. Moonen

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Genome Editing Redefines Precision Medicine in the Cardiovascular Field by Elda Dzilic, Harald Lahm, Martina Dreßen, Marcus-André Deutsch, Rüdiger Lange, Sean M. Wu, Markus Krane, Stefanie A. Doppler

“…In this review, we focus on the achievements and limitations of genome editing in the cardiovascular field. We explore different areas of cardiac research and highlight the most important developments: (1) the potential of genome editing in human pluripotent stem cells in basic research for disease modelling, drug screening, or reprogramming approaches and (2) the potential and remaining challenges of genome editing for regenerative therapies. …”
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Emerging Role of Mesenchymal Stromal Cell-Derived Extracellular Vesicles in Pathogenesis of Haematological Malignancies by Juçara Gastaldi Cominal, Maira da Costa Cacemiro, Belinda Pinto-Simões, Hans-Jochem Kolb, Kelen Cristina Ribeiro Malmegrim, Fabíola Attié de Castro

“…Multipotent mesenchymal stromal cells (MSC) are the key elements to provide the specialized bone marrow microenvironment by supporting, maintaining, and regulating the functions and fate of haematopoietic stem cells. Despite the great potential of MSC for cell therapy in several diseases due to their regenerative, immunomodulatory, and anti-inflammatory properties, they can also contribute to modulate tumor microenvironment. …”
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Study of the Structure and Properties of ZnS Utilized in a Fluorescence Biosensor by Y. Ren, H. Zhou, X. Wang, Q. W. Liu, X. D. Hou, G. F. Zhang

“…ZnS materials have been widely used in fluorescence biosensors to characterize different types of stem cells due to their excellent fluorescence effect. …”
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Human Umbilical Cord MSC-Derived Exosomes Suppress the Development of CCl4-Induced Liver Injury through Antioxidant Effect by Wenqian Jiang, Youwen Tan, Mengjie Cai, Ting Zhao, Fei Mao, Xu Zhang, Wenrong Xu, Zhixin Yan, Hui Qian, Yongmin Yan

“…Exosomes are small (30–100 nm in diameter) membrane vesicles released by different cell types and possess the similar functions with their derived cells. …”
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Three Growth Factors Induce Proliferation and Differentiation of Neural Precursor Cells In Vitro and Support Cell-Transplantation after Spinal Cord Injury In Vivo by Alexander Younsi, Guoli Zheng, Moritz Scherer, Lennart Riemann, Hao Zhang, Mohamed Tail, Maryam Hatami, Thomas Skutella, Andreas Unterberg, Klaus Zweckberger

“…Stem cell therapy with neural precursor cells (NPCs) has the potential to improve neuroregeneration after spinal cord injury (SCI). …”
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Medications for Hypertension Change the Secretome Profile from Marrow Stromal Cells and Peripheral Blood Monocytes by Nikunj Satani, Kaavya Giridhar, Chunyan Cai, Natalia Wewior, Dominique D. Norris, Jaroslaw Aronowski, Sean I. Savitz

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Skeletal Muscle Resident Progenitor Cells Coexpress Mesenchymal and Myogenic Markers and Are Not Affected by Chronic Heart Failure-Induced Dysregulations by R. I. Dmitrieva, T. A. Lelyavina, M. Y. Komarova, V. L. Galenko, O. A. Ivanova, P. A. Tikanova, N. V. Khromova, A. S. Golovkin, M. A. Bortsova, A. Sergushichev, M. Yu. Sitnikova, A. A. Kostareva

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Spleen as a Site for Hematopoiesis of a Distinct Antigen Presenting Cell Type by Helen C. O'Neill, Kristin L. Griffiths, Pravin Periasamy, Rebecca A. Hinton, Ying-Ying Hey, Sawang Petvises, Jonathan K. H. Tan

“…The novel dendritic-like cell identified in spleen is phenotypically and functionally distinct from other described antigen presenting cells. …”
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Mesenchymal Stromal Cells from the Epidermis and Dermis of Psoriasis Patients: Morphology, Immunophenotype, Differentiation Patterns, and Regulation of T Cell Proliferation by M. E. Castro-Manrreza, L. Bonifaz, O. Castro-Escamilla, A. Monroy-García, A. Cortés-Morales, E. Hernández-Estévez, J. Hernández-Cristino, H. Mayani, J. J. Montesinos

“…Psoriasis is a skin disease characterized by hyperproliferation of keratinocytes and chronic inflammation. Mesenchymal stem/stromal cells (MSCs) exhibit an immunoregulatory function that can be altered in the skin of these patients. …”
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Label-Free Imaging of Umbilical Cord Tissue Morphology and Explant-Derived Cells by Raf Donders, Kathleen Sanen, Rik Paesen, Eli Slenders, Wilfried Gyselaers, Piet Stinissen, Marcel Ameloot, Niels Hellings

“…In addition, antibody staining showed differences in Oct4, αSMA, vimentin, and ALDH1A1 expression in situ, indicating functional differences among the umbilical cord cell populations. …”
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Variability in Platelet-Rich Plasma Preparations Used in Regenerative Medicine: A Comparative Analysis by Raghvendra Vikram Tey, Pallavi Haldankar, Vivek R. Joshi, Rishi Raj, Ravindra Maradi

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Effect of Isolation Technique and Location on the Phenotype of Human Corneal Stroma-Derived Cells by Richárd Nagymihály, Zoltán Veréb, Andrea Facskó, Morten C. Moe, Goran Petrovski

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Sinusoidal Endothelial Cell Progenitor Cells Promote Tumour Progression in Patients with Hepatocellular Carcinoma by Ya-xing Feng, Wei Li, Xu-dong Wen, Ning Zhang, Wei-hui Liu, Zhan-yu Yang

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