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  1. 581

    Hyperbaric oxygen promotes both the proliferation and chemosensitization of glioblastoma cells by inhibiting HIF1α/HIF2α-ABCG2 by Sheng Gong, Pan Wang, Bin Liao, Lu Zhao, Nan Wu

    Published 2025-04-01
    “…Gain-and loss-of-function experiments suggested that ABCG2 can promote the expression of stem cell marker proteins, inhibit cell apoptosis, and promote tumor progression.ConclusionThis study confirmed that hyperbaric oxygen can inhibit ABCG2 expression through HIF1α and HIF2α, thereby promoting the proliferation and chemosensitization of gliomas.…”
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  2. 582
  3. 583

    Circadian rhythm defects in Prader-Willi syndrome neurons by A. Kaitlyn Victor, Tayler Hedgecock, Chidambaram Ramanathan, Yang Shen, Andrew C. Liu, Lawrence T. Reiter

    Published 2025-04-01
    “…Here, we investigated the circadian clock function in neurons derived from dental pulp stem cells (DPSCs) of PWS patients and neurotypical controls. …”
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  4. 584

    HIV Protein TAT Dysregulates Multiple Pathways in Human iPSCs-Derived Microglia by Liam Liyang Guo, Robert Jiang, Yan Cheng, Brooke Russell, Sanders Y. Yan, Ming-Lei Guo

    Published 2025-07-01
    “…However, due to the significant species differences between rodent and human Mg (hMg), it is essential to take caution when interpreting the results obtained from rodent models into human conditions. …”
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  5. 585

    From inserts to chips: microfluidic culture and 3D astrocyte co-culture drive functional and transcriptomic changes in hiPSC-derived endothelial cells by Tuuli-Maria Sonninen, Sanni Peltonen, Sara Kälvälä, Hoang-Tuan Nguyen, Marika Ruponen, Prateek Singh, Šárka Lehtonen

    Published 2025-06-01
    “…We aimed to investigate how different culture platforms alter the functionality and, consequently, the transcriptomic phenotype of hiPSC-derived endothelial cells (ECs). …”
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    Genome-wide identification of CAMTA gene family in teak (Tectona grandis) and functional characterization of TgCAMTA1 and TgCAMTA3 in cold tolerance by Wenlong Zhou, Jian Du, Runjie Jiao, Xianbang Wang, Tiansong Fang, Guihua Huang

    Published 2025-01-01
    “…Expression analysis of different tissues revealed the expression of TgCAMTA genes in teak roots, stems, leaves, flowers, fruits, and branches. …”
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    Differentially expressed genes of SHED based on RNA-seq analysis after long-term expansion in vitro by WANG Huihui, WU Qing, ZHAO Yumei

    Published 2023-08-01
    “…[Objective:] To investigate the differences in gene expression of stem cells derived from human exfoliated deciduous teeth (SHED) after long-term continuous subculture to passage 20 (P20) in vitro by RNA sequencing (RNA-seq) analysis technology, and to preliminarily explore their signaling pathways related to in vitro expansion and aging. …”
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  11. 591

    Activated Biocarbons Based on <i>Salvia officinalis</i> L. Processing Residue as Adsorbents of Pollutants from Drinking Water by Joanna Koczenasz, Piotr Nowicki, Karina Tokarska, Małgorzata Wiśniewska

    Published 2025-07-01
    “…This study presents research on the production of activated biocarbons derived from herbal waste. Sage stems were chemically activated with two activating agents of different chemical natures—H<sub>3</sub>PO<sub>4</sub> and K<sub>2</sub>CO<sub>3</sub>—and subjected to two thermal treatment methods: conventional and microwave heating. …”
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  12. 592

    Tuning Ru/Ni sites in the perovskite-based precursor synthesis to make more efficient and durable dual-function materials for integrated CO2 capture and methanation by Jon A. Onrubia-Calvo, Beñat Pereda-Ayo, Unai De-La-Torre, José A. González-Marcos, Juan R. González-Velasco

    Published 2025-06-01
    “…A new generation of Dual Function Materials (DFMs) were obtained after the controlled reduction of 20 % La0.6Ca0.4Ni0.95Ru0.05O3/CeO2 synthesized combining citric acid-wetness impregnation methods. …”
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    Assessing Pulmonary Function in Children and Adolescents After Cancer Treatment: Protocol for a Multicenter Cohort Study (Swiss Childhood Cancer Survivor Study FollowUp–Pulmo) by Maša Žarković, Christina Schindera, Grit Sommer, Christine Schneider, Jakob Usemann, Maria Otth, Sonja Lüer, Marc Ansari, Philipp Latzin, Claudia E Kuehni

    Published 2025-04-01
    “…Therefore, comprehensive and standardized evaluation of pulmonary function after cancer treatment in childhood, using different PFTs that include N2MBW, is needed to address these knowledge gaps and provide insights into possible early stages of pulmonary dysfunction. …”
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  17. 597
  18. 598

    Unveiling the superior function of RADA in bone regeneration compared to KSL as two critical cores within self-assembling peptide nanofibers: Insights from in vitro and in vivo stu... by Bita Rasoulian, Zahra Sheikholislam, Mohammad Hassan Houshdar Tehrani, Solmaz Chegeni, Elham Hoveizi, Seyed Mahdi Rezayat, Shima Tavakol

    Published 2024-06-01
    “…This study delved into the comparative efficacy of two distinct self-assembling peptide nanofibers, RADA-BMHP1 and KSL-BMHP1, both incorporating the biological motif of BMHP1, but differing in their core peptide sequences. Methods: Cell viability and osteogenic differentiation in rat mesenchymal stem cells (rMSCs), and bone regeneration in rat were compared. …”
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  19. 599

    Transmembrane-4 L-Six Family Member-1 Is Essential for Embryonic Blood Vessel Development by Chi-Iou Lin, Anne Merley, Hiromi Wada, Jianwei Zheng, Shou-Ching S. Jaminet

    Published 2024-11-01
    “…Transmembrane-4 L-six family member-1 (TM4SF1) is a small cell surface glycoprotein that is highly and selectively expressed on endothelial cell and mesenchymal stem cell surfaces. TM4SF1 regulates cellular functions by forming protein complexes called TMED (TM4SF1-enriched microdomains) that either recruit growth-factor activated proteins and internalize them via microtubules to distribute the recruited molecules intracellularly or support the formation of nanopodia for intercellular interactions extracellularly. …”
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  20. 600

    Patterns of Variation and Coordination in Shoot Traits Across Four Branching Orders of <i>Larix principis-rupprechtii</i> by Yang Yu, Huayong Zhang, Zhongyu Wang, Zhao Liu

    Published 2025-06-01
    “…We collected 1551 shoots of <i>Larix principis-rupprechtii</i> to examine the patterns of trait variation and coordination from different branch orders to the whole-plant level. From the perspective of the plant economic spectrum, five functional traits were selected to represent the trade-off between structural and nutrient investment: the stem diameter (SD), stem length (SL), stem dry mass (SDM), specific stem length (SSL), and stem tissue density (STD). …”
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