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Clinical and laboratory aspects of patients diagnosed with various inherited platelet disorders
Published 2025-05-01“…We identified novel mutations in GP1BA, ITGB3, NBEAL2, WAS, and MPL genes, which expanded our understanding of IPDs. Different treatment modalities were used. Hematopoietic stem cell transplantation was performed in severe systemic cases, such as Wiskott–Aldrich syndrome. …”
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Systematic Review and Meta-Analysis: Efficacy of Biologic Therapies in the Treatment of Degenerative Disc Disease
Published 2025-07-01“…Subgroup analyses revealed that stem cell therapy yielded greater efficacy than PRP in both pain relief and functional improvement outcomes. …”
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504
HIPSC-DIFFERENTIATED DOPAMINERGIC NEURONS ARE A USEFUL TOOL FOR STUDYING THEIR NEUROPHYSIOLOGY AND MATURATION
Published 2025-04-01“…This study investigates the functional maturation of DA neurons derived from human induced pluripotent stem cells (IPS). …”
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A preliminary bioinformatic screen to identify SRI SMC2 PSIP1 TLE4 and MSX1 as potential diagnostic and prognostic markers of osteoarthritis
Published 2025-08-01“…OA-affected synovium and chondrocytes present differences between aurora B and A signaling. However, major biological pathways are similarly enriched with SRI, SMC2, PSIP1, TLE4, and MSX1 genes identified as prominent molecular biomarkers of OA progression and mesenchymal stem cell-based OA regeneration. …”
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506
Layered Double Hydroxides as Systems for Capturing Small-Molecule Air Pollutants: A Density Functional Theory Study
Published 2024-10-01“…Despite the efforts to stem their diffusion, many diseases are still associated with exposure to these molecules. …”
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507
Harnessing cell size to separate genetically and functionally distinct dental pulp-derived mesenchymal stromal cell subpopulations
Published 2025-06-01“…Recent research has unveiled a strong correlation between the biophysical characteristics of culture-expanded stem cells and their functional attributes, thereby raising the prospect of employing high-throughput, cost-effective biophysical sorting techniques to isolate functionally distinct subpopulations. …”
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The Synthetic Cannabinoids ADB-FUBINACA Modulate Mitochondrial Function and Dynamics at Biologically Relevant Concentrations During In Vitro Neurodifferentiation
Published 2024-12-01“…Different mechanisms seem to underlie mitochondrial function-related effects, as only the modulation of energy supply was dependent on CB1R activation. …”
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510
Application of Standardized <i>Rosa damascena</i> Stem Cell-Derived Exosomes in Dermatological Wound Healing and Scar Management: A Retrospective Case-Series Study with Long-Term O...
Published 2025-07-01“…<b>Objectives</b>: To evaluate the efficacy and long-term outcomes of Damask rose stem-cell-derived exosome (RSCE) therapy in the management of diverse dermatological conditions, including traumatic wounds, surgical scars, and atrophic acne scars. …”
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511
Investigating POU3F4 in cancer: Expression patterns, prognostic implications, and functional roles in tumor immunity
Published 2025-01-01“…Research has demonstrated that POU3F4 is integral to various cancers, in addition to its significance in inner ear development, pancreatic differentiation, as well as neural stem cell differentiation. Nevertheless, comprehensive pan-cancer analyses focusing on POU3F4 remain limited. …”
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Bioinformatics and Functional Validation of <i>CqPRX9L1</i> in <i>Chenopodium quinoa</i>
Published 2025-07-01“…The expression of <i>CqPRX9L1</i> was relatively higher in ears and roots at the panicle stage than in stems and leaves. <i>CqPRX9L1</i> showed a dynamic expression pattern of first decreasing and then increasing under abiotic stresses such as 15% PEG 6000, low temperature, and salt damage, with differences in response time and degree. …”
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Divergence in leaf and cambium phenologies among three temperate tree species of different wood types with special reference to xylem hydraulics
Published 2025-03-01“…The leaf phenology preceded the onset of cambial activity in the Populus species, which was permitted by the ability of diffuse-porous species in largely retaining the stem hydraulic function over the winter. In contrast, the Ulmus species with ring-porous wood had to restore its severely hampered stem hydraulic function by winter embolism before leaf flush. …”
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MSC-Derived Extracellular Vesicles: Roles and Molecular Mechanisms for Tissue Repair
Published 2025-06-01“…Here, we reviewed the characteristics of different subtype of MSC-EVs, the functional molecules in MSC-EVs for tissue repair, the potential applications of MSC-EVs for different tissue injuries in recent three years, and the clinical progress as well as the existing challenges in MSC-EV based therapy. …”
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