Cyclooxygenase-2 negatively regulates osteogenic differentiation in murine bone marrow mesenchymal stem cells via the FOXO3a/p27kip1 pathway by Shu-Chun Chuang, Ya-Shuan Chou, Yi-Shan Lin, Je-Ken Chang, Chung-Hwan Chen, Mei-Ling Ho

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IL-27 Modulates Mesenchymal Stem Cell Immunoplasticity for Enhanced Lupus Nephritis Therapy via the JAK1–STAT1–IDO Axis and Tryptophan Metabolic Orchestration by Cheng Zhou, Shunlai Shang, Jing Zhao, Yunzhao Yang, Meihan Shi, Ping Li, Qinggang Li, Jian Zhang, Wenge Li, Chuyue Zhang, Xue-Yuan Bai

“…Lupus nephritis is recognized as a common and severe complication of systemic lupus erythematosus, without an optimal therapeutic strategy currently available. While mesenchymal stem cells (MSCs) hold therapeutic promise, their efficacy varies substantially, likely due to their plasticity and capacity to adopt pro-inflammatory (MSC1) or anti-inflammatory (MSC2) functional states in response to different microenvironments. …”
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Impacts of different types of straw returning on soil physicochemical properties, microbial community structure, and pepper quality by Xiapu Gai, Biao Chen, Shijuan Xiong, Qingqing Zhou, Yuan Yuan, Yumei Mou

“…MS treatment increased amino acids (59.6%) and crude fat (6.3%), which was related to the different metabolic pathways caused by the difference in carbon-nitrogen ratio. …”
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Acceleration of Functional Maturation and Differentiation of Neonatal Porcine Islet Cell Monolayers Shortly In Vitro Cocultured with Microencapsulated Sertoli Cells by Francesca Mancuso, Mario Calvitti, Giovanni Luca, Claudio Nastruzzi, Tiziano Baroni, Stefania Mazzitelli, Ennio Becchetti, Iva Arato, Carlo Boselli, Monique D. Ngo Nselel, Riccardo Calafiore

“…Starting from isolated neonatal porcine pancreatic islets (NPIs), we have obtained cell monolayers that were exposed to microencapsulated monolayered Sertoli cells (ESCs) for different time periods (7, 14, 21 days). To assess the development of the cocultured cell monolayers, we have studied either endocrine cell phenotype differentiation markers or c-kit, a hematopoietic stem cell marker, has recently been involved with growth and differentiation of β-cell subpopulations in human as well as rodent animal models. …”
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Functionally enriched epigenetic clocks reveal tissue-specific discordant aging patterns in individuals with cancer by Chiara M. S. Herzog, Elisa Redl, James Barrett, Sepideh Aminzadeh-Gohari, Daniela D. Weber, Julia Tevini, Roland Lang, Barbara Kofler, Martin Widschwendter

“…Epigenetic alterations such as DNA methylation (DNAme) changes are a hallmark of aging and form the basis of so-called epigenetic clocks, yet their functional relevance and directionality in different organs during disease development is often unclear. …”
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Acute Oral Toxicological Profile of Croton membranaceus Mull. Arg. Aqueous Stem Extract, a Herbal Treatment for Benign Prostate Hyperplasia, in Male Sprague–Dawley Rats by Daniel Kwame Afriyie, Elvis Ofori Ameyaw, Isaac Tabiri Henneh, George Asare, Ebenezer Ofori-Atta, Seth Kwabena Amponsah, Regina Appiah-Opong

“…The objective of this study was to determine the acute oral toxicity of the aqueous stem extract of Croton membranaceus (CMASE) in male Sprague–Dawley (S-D) rats. …”
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FOXO1 and FYN Expression Trends in Breast Cancer Stem Cells: An Integrative Study of Single Nucleotide Polymorphism (SNP) Array and Quantitative PCR (qPCR) Analysis by Ay Ly Margaret, Septelia Inawati Wanandi, Fadilah Fadilah, Rafika Indah Paramita

“…BACKGROUND: Currently, identification of breast cancer stem cells (BCSCs) commonly relies on CD24-/CD44+ expression profiles. …”
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Phenology analysis for trait prediction using UAVs in a MAGIC rice population with different transplanting protocols by Shoji Taniguchi, Toshihiro Sakamoto, Haruki Nakamura, Yasunori Nonoue, Di Guan, Akari Fukuda, Hirofumi Fukuda, Kaede C. Wada, Takuro Ishii, Jun-Ichi Yonemaru, Daisuke Ogawa

“…However, whether CH parameters are applicable to other rice populations and to different cultivation methods, and whether vegetation indices such as the chlorophyll index green (CIg) can function for phenotype prediction remain to be elucidated. …”
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Allometric Growth of Annual <i>Pinus yunnanensis</i> After Decapitation Under Different Shading Levels by Pengrui Wang, Chiyu Zhou, Boning Yang, Jiangfei Li, Yulan Xu, Nianhui Cai

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Roles of extracellular vesicles from different origins in metabolic-associated fatty liver disease: progress and perspectives by Jing Wang, Shuoqiang Bao, Qi An, Caihong Li, Juan Feng

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Executive function and neural oscillations in adults with attention-deficit/hyperactivity disorder: a systematic review by Ziyao Su, Ziyao Su, Yingtan Wang, Yingtan Wang, Bin Wang, Bin Wang, Chuanliang Han, Haoran Zhang, Haoran Zhang, Yanyan Gu, Yanyan Gu, Yu Chen, Yu Chen, Xixi Zhao, Xixi Zhao, Yuwei Shi

“…The aims of this systematic review were as follows: (1) To discern whether there were any differences in resting-state electroencephalogram (EEG) and event related potential (ERP) between adult ADHD and healthy controls (HCs). (2) To ascertain whether ERP specific manifestations associated with executive function (EF) deficiencies. (3) To conduct an exploration into the mechanisms of specific electrophysiologic alterations. …”
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Amine-functionalized cellulose-silica composites for the remediation of hexavalent chromium (Cr IV) in contaminated water by Mayenzeke Trueman Mazibuko, Stanley Chibuzor Onwubu, Phumlane Selby Mdluli, Vimla Paul, Mokhena Clement Teboho, Mokhothu Thabang

“…We employed the in-situ sol–gel method to create cellulose-silica silane functionalized composites, analyzing them through different characterization techniques such as Attenuated total reflectance- Fourier transform infrared spectroscopy (ATR-FTIR), X-ray Diffraction Analysis (XRD), Thermo gravimetric analysis (TGA)/differential thermogravimetric (DTG), Brunauer–Emmett–Teller (BET), Scanning Electron Microscopy (SEM), and Transmission Electron Microscopy (TEM) techniques. …”
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Simple Limbal Epithelial Transplantation (SLET): case reports by João Pedro Gomes Henn da Silva, Mártin Luís Stival Marquezan, Ricardo Alexandre Stock, Elcio Luiz Bonamigo

“…The limbus is a transition zone between the cornea and the conjunctiva of the eye, housing epithelial stem cells responsible for maintaining and ensuring the proper functioning of the cornea. …”
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Dairy intake and cognitive function in older adults in three cohorts: a mendelian randomization study by Natalia Ortega, Nick J. Mueller, Abbas Dehghan, Tosca O. E. de Crom, Armin von Gunten, Martin Preisig, Pedro Marques-Vidal, Marco Vinceti, Trudy Voortman, Nicolas Rodondi, Patricia O. Chocano-Bedoya

“…Such inconsistencies might stem from different FFQs across cohorts and consumption ranges. …”
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3D in vitro modeling of neural microenvironment through a multi-scaffold assembly approach by Cecilia Traldi, Vanessa Chiappini, Silvia Chasseur, Federica Aiello, Marina Boido, Chiara Tonda-Turo

“…Extrusion-based 3D bioprinting is employed to accurately position neural stem cells (NSCs) embedded in a gelatin methacryloyl hydrogel onto an aligned microfibrous polycaprolactone structure obtained by melt electrowriting. …”
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Brain organoid models for studying the function of iPSC-derived microglia in neurodegeneration and brain tumours by Angelica Maria Sabogal-Guaqueta, Teresa Mitchell-Garcia, Jasmijn Hunneman, Daniëlle Voshart, Arun Thiruvalluvan, Floris Foijer, Frank Kruyt, Marina Trombetta-Lima, Bart J.L. Eggen, Erik Boddeke, Lara Barazzuol, Amalia M. Dolga

“…Pluripotent stem cell technology has facilitated the generation of highly complex models, allowing the study of control and patient-derived microglia in vitro. …”
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Gradient boosting regression for faster Partitioned Iterated Function Systems‐based head pose estimation by Paola Barra, Riccardo Distasi, Chiara Pero, Stefano Ricciardi, Maurizio Tucci

“…While, in general, HPE can be performed on both still images and frames extracted from live video or captured footage, its functional approach and the related processing pipeline may have a significant impact on suitability to different application contexts. …”
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Lipid profile changes in patients with acute leukemia after pathogenetic therapy by E. A. Praskurnichy, V. О. Dzidzaria, Yu. S. Kitaeva

“…All patients in the study group underwent an assessment of lipid profile, as well as an assessment of liver and kidney function at the time of diagnosis, the end of chemotherapy courses, and after allogeneic hematopoietic stem cell transplantation.Results. …”
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Subgenic Pol II interactomes identify region‐specific transcription elongation regulators by Kevin M Harlen, L Stirling Churchman

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Exosomes and immune modulation: implications for neuroblastoma immunotherapy by Martina Morini, Chiara Vitale, Martina Ardito, Alessandra Dondero, Katia Cortese, Cristina Bottino, Cristina Bottino, Roberta Castriconi, Roberta Castriconi

“…Tumor-derived exosomes (TDEs) promote tumor progression by creating an immunosuppressive tumor microenvironment (TME), inhibiting T and NK cell activity, preventing dendritic cell maturation, and expanding immunosuppressive cell populations. Cancer Stem Cell (CSC)-derived exosomes further trigger functional changes in immune cells subsets, enhancing immune suppression. …”
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