Phenotypic and Proteomic Characteristics of Human Dental Pulp Derived Mesenchymal Stem Cells from a Natal, an Exfoliated Deciduous, and an Impacted Third Molar Tooth by Gurler Akpinar, Murat Kasap, Ayca Aksoy, Gokhan Duruksu, Gulcin Gacar, Erdal Karaoz

“…The cells were isolated from a natal (NDPSCs), an exfoliated deciduous (stem cells from human exfoliated deciduous (SHED)), and an impacted third molar (DPSCs) tooth of three different donors. …”
Get full text

Relationship Between Location of Cell Transplantation and Recovery for Intracerebral Stem Cell Transplantation for Chronic Traumatic Brain Injury: Post-hoc Analysis of STEMTRA Tria... by Masahito Kawabori, Yasuaki Karasawa, Jun Suenaga, Hajime Nakamura, Hideaki Imai, Takao Yasuhara, Naoki Tani, Tatsuya Sasaki, Takashi Kawasaki, Kenta Totsuka, Dai Chida, Yoichi M. Ito, Tetsuya Yamamoto, Isao Date, Shota Tanaka, Haruhiko Kishima, Miki Fujimura

“…This study included all Japanese subjects from the STEMTRA trial who were assigned to the cell transplantation group. Functional recovery was assessed by the difference in Fugl–Meyer Motor Scale (FMMS) scores between the screening period and 24 or 48 weeks post-transplantation. …”
Get full text

Bisphenol S interrupted axonogenesis on a human embryonic stem cells derived neural differentiation model: Conserved axon guidance and WNT signaling pathway involved by Wanqing Guo, Wei Xiong, Liang Wang, Xiaoya Wang, Yongru Zhou, Yili Chen, Xiaomeng Li, Lishi Zhang, Mengmei Ni, Jinyao Chen

“…In present study, the neuro-differentiating human embryonic stem cells, hESC, was exposed to BPS (0–375 µM) at different stages (the precursor stage, the precursor to maturation stage, and the whole differentiation stage) to assess the potential neurodevelopmental toxicity and its mechanisms. …”
Get full text

High NK cell counts at day 90 predict improved survival in event-free patients after T-cell depleted allogeneic stem cell transplantation by Andrej Pešić, Nevena Bešević, Nicolaus Kröger, Dejana Stanisavljević, Dejana Stanisavljević, Nada Kraguljac Kurtović, Zoran Bukumirić, Zoran Bukumirić, Natalija Kecman, Nikola Lemajić, Mihailo Smiljanić, Nada Suvajdžić Vuković, Nada Suvajdžić Vuković, Andrija Bogdanović, Andrija Bogdanović, Ana Vidović, Ana Vidović, Jelena Bila, Jelena Bila, Mirjana Mitrović, Mirjana Mitrović, Danijela Leković, Danijela Leković, Marijana Virijević, Marijana Virijević, Irena Đunić, Irena Đunić, Darko Antić, Darko Antić, Milena Todorović Balint, Milena Todorović Balint

“…However, data on the impact of different lymphocyte subsets influencing outcomes is conflicting. …”
Get full text

Effect of <i>CTLA4</i> gene polymorphism on relapse probability among patients with acute leukemias after allogenic hematopoietic stem cells transplantation by D. S. Romaniuk, A. A. Khmelevskaya, M. Yu. Drokov, N. N. Popova, V. A. Vasilieva, L. A. Kuzmina, G. A. Efimov, E. N. Parovichnikova, V. G. Savchenko

“…Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is being widely applied as a therapy for hematological malignancies. …”
Get full text

PSMB10 maintains the stemness of chemotherapeutic drug-resistant leukemia cells by inhibiting senescence and cytotoxic T lymphocyte-mediated killing in a ubiquitinated degradation... by Xiao Ma, Yingnan Li, Di Wang, Jialan Niu, Qian Li, Ying Chen, Mengyuan Wang, Jin Wen, Chenxi Liao, Nan Wang, Xiaolan Zhang, Jiwei Chang, Jiayi Yang, Lei Li, Jing Zou, Danyue Peng, Lingbo Liu

“…The genetic inactivation of PSMB10 resulted in increased senescence and cytotoxic T lymphocyte (CTL) killing, as well as increased intracellular drug concentrations and drug-induced cellular senescence in different types of human AML cells, which also impeded human and murine leukemia initiation and stemness maintenance in vivo with a 19-fold decrease in the frequency of human LSCs and a 7.6-fold decrease of drug-resistant mouse LSCs, while normal hematopoietic cells remained unaffected. …”
Get full text

Identification of peptidome-based biomarkers of cassava mosaic disease resistance in different cassava varieties by Wanwisa Siriwan, Sawanya Charoenlappanit, Narumon Phaonakrop, Siriwan Thaisakun, Sittiruk Roytrakul

Get full text

Integrated Genome-Wide Analysis of Gene Expression and DNA Copy Number Variations Highlights Stem Cell-Related Pathways in Small Cell Esophageal Carcinoma by Di Liu, Xinyan Xu, Junmiao Wen, Liyi Xie, Junhua Zhang, Yuxin Shen, Guoliang Jiang, Jiayan Chen, Min Fan

Get full text

Histological Alterations and Interferon-Gamma and AKT-mTOR Expression in an Experimental Model of Achilles Tendinopathy—A Comparison of Stem Cell and Amniotic Membrane Treatment by Guilherme Vieira Cavalcante, Rosangela Fedato, Lucia de Noronha, Seigo Nagashima, Ana Paula Camargo Martins, Márcia Olandoski, Ricardo Pinho, Aline Takejima, Rossana Simeoni, Julio Cesar Francisco, Luiz César Guarita-Souza

“…The search for new therapeutic tools, using cell therapies with stem cells (SC) and biological tissues, such as amniotic membranes (AM), has proved useful for the regeneration of injured tendons. …”
Get full text

Computational analysis of spliced leader trans-splicing in the regenerative flatworm <i>Macrostomum lignano</i> reveals its prevalence in conserved and stem cell related genes by K. V. Ustyantsev, E. V. Berezikov

“…However, only a fraction of trans-spliced genes reside in operons, suggesting that SL trans-splicing must also have some other, less understood functions. Regenerative flatworms are informative model organisms which hold the keys to understand the mechanism of stem cell regulation and specialization during regeneration and homeostasis. …”
Get full text

Molecular and morphological peculiarities of chronic placental insufficiency formation caused by different types of diabetes mellitus by Tatyana G. Tral, Gulrukhsor Kh. Tolibova, Ekaterina V. Musina, Maria I. Yarmolinskaya

Get full text

Characterization and Functional Analysis of 4-Coumarate:CoA Ligase Genes in Mul-berry. by Chuan-Hong Wang, Jian Yu, Yu-Xiang Cai, Pan-Pan Zhu, Chang-Ying Liu, Ai-Chun Zhao, Rui-Hua Lü, Meng-Jiao Li, Feng-Xiang Xu, Mao-De Yu

Get full text

Delivery of A Chemically Modified Noncoding RNA Domain Improves Dystrophic Myotube Function by Zeinabou Niasse‐Sy, Bo Zhao, Ajda Lenardič, Huyen Thuc Tran Luong, Ori Bar‐Nur, Johan Auwerx, Martin Wohlwend

“…Here, we identify an independent functional element within human CYTOR, and optimize its RNA delivery. …”
Get full text

Umbilical Cord-Derived Mesenchymal Stem Cells Attenuate S100-Induced Autoimmune Hepatitis via Modulating Th1 and Th17 Cell Responses in Mice by Xiaofeng Wei, Xinhong Cheng, Yang Luo, Xun Li

“…Previous studies reported on the applicability and safety of mesenchymal stem cells (MSCs) to ameliorate liver inflammation and fibrosis. …”
Get full text

ABCB1 confers resistance to carboplatin by accumulating stem-like cells in the G2/M phase of the cell cycle in p53null ovarian cancer by Danbi Lee, Hyun-Seok Jeong, Sun-Young Hwang, Yu-Gyeong Lee, Youn-Jung Kang

“…This suggests that high levels of stemness and attenuated DNA repair function exhibited in the G2/M-accumulated portion may be a key contributor of chemoresistance in patients with ovarian cancer bearing a p53null mutation, but not other types of mutations expressing p53. …”
Get full text

Human spindle-shaped urine-derived stem cell exosomes alleviate severe fatty liver ischemia–reperfusion injury by inhibiting ferroptosis via GPX4 by Shangheng Shi, Cunle Zhu, Shangxuan Shi, Xinqiang Li, Imran Muhammad, Qingguo Xu, Xinwei Li, Ziyin Zhao, Huan Liu, Guangming Fu, Meiying Song, Xijian Huang, Feng Wang, Jinzhen Cai

“…Abstract Background Severe hepatic steatosis can exacerbate Ischemia–reperfusion injury (IRI), potentially leading to early graft dysfunction and primary non-function. In this study, we investigated the heterogeneity of different subpopulations of Urine-derived stem cells (USCs) to explore the most suitable cell subtype for treating severe steatotic liver IRI. …”
Get full text

Effects of Human Mesenchymal Stem Cells Isolated from Wharton’s Jelly of the Umbilical Cord and Conditioned Media on Skeletal Muscle Regeneration Using a Myectomy Model by T. Pereira, P. A. S. Armada-da Silva, I. Amorim, A. Rêma, A. R. Caseiro, A. Gärtner, M. Rodrigues, M. A. Lopes, P. J. Bártolo, J. D. Santos, A. L. Luís, A. C. Maurício

“…The in vivo application of human mesenchymal stem cells (HMSCs) of the umbilical cord and the conditioned media (CM) where the HMSCs were cultured and expanded, associated with different vehicles to induce muscle regeneration, was evaluated in a rat myectomy model. …”
Get full text

Diversity of Antifungal Properties in Bacterial Isolates from Different Plant Species Growing Across Uzbekistan by Mukhlisa K. Shodmonova, Dono A. Muhammadova, Ilkham S. Aytenov, Marufbek Z. Isokulov, Tohir A. Bozorov, Daoyuan Zhang, Ozodbek S. Abduraimov, Sojida M. Murodova, Fazliddin A. Melikuziev, Bekhruz O. Ochilov, Sodir K. Meliev

“…To investigate the competitive dynamics between phytopathogenic fungi and plant-associated bacteria, we collected stem and root samples from 50 plant species across nine regions of Uzbekistan. …”
Get full text

Where to act, when to think, and how to feel: The ABC + model of learning engagement and its relationship to the components of academic performance by Eric T. McChesney, Christian D. Schunn, Linda DeAngelo, Erica McGreevy

Get full text

Assessing the Effect of Fatigue on Swallowing Function in Adults with Acute Stroke. A Pilot Study by Hope E. Baylow, DA

Get full text