GFAPβ and GFAPδ Isoforms Expression in Mesenchymal Stem Cells, MSCs Differentiated Towards Schwann-like, and Olfactory Ensheathing Cells by Nidia Jannette Carrillo González, Gabriela Stefania Reyes Gutierrez, Tania Campos-Ordoñez, Rubén D. Castro-Torres, Carlos Beas Zárate, Graciela Gudiño-Cabrera

“…Olfactory ensheathing cells (OECs) and mesenchymal stem cells (MSCs) differentiated towards Schwann-like have plasticity properties. …”
Get full text

Functional hemispheric disconnection procedures for chronic epilepsy: history, indications, techniques, complications and current practice in Europe. A consensus statement on behal... by Olaf E.M.G. Schijns, Daniel Delev, Marec von Lehe, Dirk van Roost, Karl Rössler, Tom Theys, Christian Auer, Thomas Blauwblomme, Marcelo Budke, Alexandre Rainha Campos, Santiago Candela Canto, Hans Clusmann, Christian Dorfer, Georg Dorfmüller, Arild Egge, Lorand Eröss, Sarah Ferrand-Sorbets, Flavio Giordano, Jürgen Honegger, Cihan Isler, Jugoslav Ivanovic, Thilo Kalbhenn, Atte Karppinen, Niklaus Krayenbühl, Rick H.G.J. van Lanen, Carlo E. Marras, Ioannis Mavridis, Daniel Nilsson, Julia Onken, Christian Raftopoulos, Jonathan Roth, Jordi Rumia, Thomas Sauvigny, Didier Scavarda, Karl Schaller, Christian Scheiwe, Sophie Schuind, Alexandra Seromenho-Santos, Kostas Fountas

“…Here, a task force of European epilepsy surgeons prepared, on behalf of the EANS Section for Functional Neurosurgery, a consensus statement on different aspects of the hemispheric disconnection procedure. …”
Get full text

Organoids as powerful models of endometrium epithelium in transcriptomic, cellular and functional mimicry by Martina Ciprietti, Celine Bueds, Hugo Vankelecom, Joris Vriens

Get full text

Lung organoids in COPD: recent advances and future prospects by Yajie Huo, Shengyang He, Yan Chen

“…Lung organoids are in vitro models derived from adult stem cells, human pluripotent stem cells, or embryonic stem cells, established through three-dimensional culture. …”
Get full text

A study devoted to the design of a special nozzle with multiple functions by WANG Yong-bin, SHI Yi-ping, HU Jia-fen

Get full text

D-Mannose Inhibits Adipogenic Differentiation of Adipose Tissue-Derived Stem Cells via the miR669b/MAPK Pathway by Yitong Liu, Lijia Guo, Lei Hu, Chen Xie, Jingfei Fu, Yiyang Jiang, Nannan Han, Lu Jia, Yi Liu

“…The adipogenic differentiation of adipose tissue-derived stem cells (ADSCs) plays an important role in the process of obesity and host metabolism. …”
Get full text

Fascia-derived stem cells enhance fat graft retention by promoting vascularization through the HMOX1-HIF-1α pathway by Guo Chen, Jie Long, Yuge Zhang, Xuhua Zhou, Botao Gao, Zijin Qin, Yuhan Zhu, Binyu Song, Ziwei Cui, Zhangzi liu, Man Xu, Zhou Yu, Baoqiang Song, Ziang Zhang

“…Through bioinformatics analysis and functional experiments, we identified significant differences in the angiogenic potential of the two cell types. …”
Get full text

The gut microbial metabolite indole-3-aldehyde alleviates impaired intestinal development by promoting intestinal stem cell expansion in weaned piglets by Jiaqi Zhang, Yahui Chen, Xin Guo, Xuan Li, Ruofan Zhang, Mengting Wang, Weiyun Zhu, Kaifan Yu

“…Furthermore, we explored the effects of dietary indole-3-aldehyde (IAld), a key tryptophan metabolite, on intestinal development and gut barrier function in weaned piglets. Supplementation with 100 mg/kg IAld in the diet increased the small intestine index and improved intestinal barrier function by promoting intestinal stem cell (ISC) expansion in piglets. …”
Get full text

Seashore paspalum in the Mediterranean transition zone: phenotypic traits of twelve accessions during and after establishment by Monica Gaetani, Marco Volterrani, Simone Magni, Lisa Caturegli, Alberto Minelli, Claudio Leto, Salvatore La Bella, Teresa Tuttolomondo, Giuseppe Virga, Nicola Grossi

“…Nonetheless, little is known on the performance of the different commercial cultivars of Paspalum vaginatum in this climatic zone. …”
Get full text

Nanoscale therapeutics for erectile dysfunction: a meta-analysis of stem cell-derived extracellular vesicles as natural nanoparticles in diabetic rat models by Kecheng Lou, Junjie Hu, Jiayue Tong, Zhanshi Wang

“…Subgroup analyses revealed no significant differences between EV sources (e.g., mesenchymal stem cells [MSCs] vs. adipose-derived stem cells [ADSCs], P > 0.05) or disease models (diabetes mellitus [DM] vs. cavernous nerve injury [CNI], P > 0.05). …”
Get full text

Relation between drought-exposed photosynthetic apparatus and tree water deficit derived from stem diameter variations in Norway spruce seedlings by Ayaz Sajad Muhammad, Húdoková Hana, Jamnická Gabriela, Fleischer Peter, Ditmarová Ľubica, Razzak Abdul, Ježík Marek

“…Growth and TWD parameters, as well as those of gas exchange and most of the chlorophyll a fluorescence parameters differed against C trees during drought. Thus, the parameters derived from SDV may serve as indicators of the functionality of photosynthetic apparatus.…”
Get full text

Neural-induced human adipose tissue-derived stem cell secretome exerts neuroprotection against rotenone-induced Parkinson’s disease in rats by Mahesh Ramalingam, Sujeong Jang, Jinsu Hwang, Hyong-Ho Cho, Byeong C. Kim, Han-Seong Jeong

“…Conclusions NI-hADSC-CM and NI-hADSC-Exo significantly exerted neuroprotection by decreasing α-syn toxicity, inhibiting neuroinflammation and apoptosis, restoring autophagic flux properties, and promoting the neuronal function in ROT-injected rats; however, the influence of these treatments on signaling pathways differed slightly between the midbrain and striatum regions. …”
Get full text

Periostin Is a Candidate Regulator of the Host Microenvironment in Regeneration of Pulp and Dentin Complex and Periodontal Ligament in Transplantation with Stem Cell-Conditioned Me... by Shintarou Sakatoku, Yuki Hayashi, Taku Futenma, Yoshihiko Sugita, Ryo Ishizaka, Hiroyuki Nawa, Koichiro Iohara

“…Periostin is also found in the epithelial–mesenchymal junction, with expression sites that differ depending on the mineralized matrix stage, and is involved in regulation of calcification. …”
Get full text

Hip arthroplasty following failure of internal fixation in intertrochanteric femoral fractures: classification decision-making for femoral stem selection and clinical validation by Jiexin Huang, Lan Lin, Jianhua Lyu, Xinyu Fang, Wenming Zhang

“…Results The Classification-based Decision Group did not differ significantly from the Non-classification Decision Group in operation time, blood loss, or the use of cemented stems. …”
Get full text

Ganoderma Disease in Oil Palm Trees Using Hyperspectral Imaging and Machine Learning by Chee Seng Kwang, Siti Fatimah Abdul Razak, Sumendra Yogarayan, M. Z. Adli Zahisham, Tze Huey Tam, M. K. Anuar Mohd Noor, Haryati Abidin

“…However, the industry faces the challenge of Ganoderma infection, a destructive disease affecting oil palm trees that causes base stem rot (BSR). To address this issue, a novel method is proposed for detecting Ganoderma disease in oil palm trees by combining hyperspectral imaging and machine learning techniques. …”
Get full text

Cancer stem cells and Lon-noncRNA promotes invasion, metastasis and tumor growth in breast cancer through regulation of signaling pathway by Nour H. Elbazzar, Inas Moaz, Abeer A. Bahnassy, Ahmed El sherif, Ola S. Ahmed

“…Conversely, the expression levels of HOTAIR, UCA1, MALAT1, and ZEB did not show statistically significant differences between the two groups (p > 0.05). Correlation analysis indicated a strong positive association between FOXC2 and SNAIL expression (r = 0.41), suggesting a potential shared functional role in disease progression. …”
Get full text

Unravelling axonal transcriptional landscapes: insights from induced pluripotent stem cell-derived cortical neurons and implications for motor neuron degeneration by Jishu Xu, Michaela Hörner, Maike Nagel, Perwin Perhat, Milena Korneck, Marvin Noß, Stefan Hauser, Ludger Schoels, Jakob Admard, Nicolas Casadei, Rebecca Schuele

“…Neuronal function and pathology are deeply influenced by the distinct molecular profiles of the axon and soma. …”
Get full text

Elucidating the Role of FASN in Lung Cancer Stem Cells in Sensitive and Resistant EGFR-Mutated Non-Small Cell Lung Cancer Cells by Polonio-Alcalá E, Ausellé-Bosch S, Riesco-Llach G, Novales P, Feliu L, Planas M, Ciurana J, Puig T

“…Keywords: lung cancer stem cells, FASN, EGCG synthetic derivative, NSCLC, 3D cell culture, AKT…”
Get full text

Catalpol Enhances Osteogenic Differentiation of Human Periodontal Stem Cells and Modulates Periodontal Tissue Remodeling in an Orthodontic Tooth Movement Rat Model by Hu J, Song Y, Zhang Y, Yang P, Chen S, Wu Z, Zhang J

“…Tests were analyzed using GraphPad Prism 8 software. Differences among more than two groups were analyzed by one-way or two-way analysis of variance (ANOVA) followed by the Tukey’s test. …”
Get full text

Research Progress in Diseases Caused by STAT1 Gain-of-Function Mutations by LI Linpeng, MA Jing, GU Hao, SHU Zhou, MAO Huawei

“…For the treatment of STAT1-GOF, such as targeted therapy with ruxolitinib for STAT1 hyperphosphorylation, immunomodulatory therapy and hematopoietic stem cell transplantation for different self-immune systems, certain curative effects can be obtained. …”
Get full text