FAK mediates BMP9-induced osteogenic differentiation via Wnt and MAPK signaling pathway in synovial mesenchymal stem cells by Weiwei Zheng, Xueping Gu, Xingwei Sun, Qin Wu, Hu Dan

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Mesenchymal Stem Cell Therapy Using Human Umbilical Cord in a Rat Model of Autoimmune-Induced Premature Ovarian Failure by Zhe Wang, Quanwei Wei, Hao Wang, Linxiao Han, Hongjian Dai, Xiaoxin Qian, Hongliang Yu, Manqun Yin, Fangxiong Shi, Nianmin Qi

“…Human umbilical cord mesenchymal stem cells (UCMSCs) can be used for tissue regeneration and repair. …”
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Rice Responses to the Stem Borer <i>Diatraea saccharalis</i> (Lepidoptera: Crambidae) by Infrared-Thermal Imaging: Implications for Field Management by Rodrigo de Almeida Rocha, Pedro Valasco dos Santos, Juliano de Bastos Pazini, André Cirilo de Sousa Almeida, Anderson Rodrigo da Silva

“…A generalized linear mixed model was applied to the data obtained from leaf temperature as a function of infestation level throughout the infestation period, using the F-test to detect significant differences between cultivars. …”
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The controversial role of CD151 in different solid tumors: promoter or suppressor? by Xue Gao, Sa Liu, Yubo Cao, Lei Shi, Yuanqin Yin

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Syngeneic Transplantation of Olfactory Ectomesenchymal Stem Cells Restores Learning and Memory Abilities in a Rat Model of Global Cerebral Ischemia by Antoine D. Veron, Cécile Bienboire-Frosini, Stéphane D. Girard, Kevin Sadelli, Jean-Claude Stamegna, Michel Khrestchatisky, Jennifer Alexis, Patrick Pageat, Pietro Asproni, Manuel Mengoli, François S. Roman

“…Among the different stem cell types, the “olfactory ectomesenchymal stem cells” (OE-MSCs) located in the adult olfactory mucosa stand as one of the best candidates. …”
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RNA Sequencing Identifies Novel Signaling Pathways and Potential Drug Target Genes Induced by FOSL1 in Glioma Progression and Stemness by Guo S, Sidhu R, Ramar V, Guo AA, Wang G, Liu M

“…Notably, 8 upregulated (ITGA5, SDC1, PHLDB2, TNFRSF8, ADAM8, TLR7, STEAP3, and POU3F2) and 4 downregulated (IFIT1, FBXO16, ARL3, and BEX1) genes were identified, with implications for glioblastoma prognosis.Conclusion: This transcriptome investigation emphasizes the diverse functions of FOSL1 in different biological processes and signaling networks during the shift from proneural to mesenchymal state in glioblastoma.Keywords: glioma, RNA sequencing, FOSL1, NF-κB, glioma stem cells, signaling pathways…”
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Preclinical safety and efficacy evaluation of the intrathecal transplantation of GMP-grade human umbilical cord mesenchymal stem cells for ischemic stroke by Zejia Huang, Jiaohua Jiang, Qingxia Peng, Mengzhi Jin, Yakun Dong, Xuejia Li, Ermei Luo, Haijia Chen, Yidong Wang

“…There was no abnormal differentiation or tumor formation in various organs of rats in any group. (2) Compared with saline-treated animals, those treated with human umbilical cord mesenchymal stem cells showed significant functional recovery and reduced infarct volume, with no significant differences between different human umbilical cord mesenchymal stem cell doses. (3) Human umbilical cord mesenchymal stem cells were found in the ischemic brain after 14 and 28 days of follow-up, and the number of positive cells significantly decreased over time. (4) Neuronal nuclei expression in the human umbilical cord mesenchymal stem cell group was greater than that in the saline group, while glial fibrillary acidic protein and ionized calcium binding adaptor molecule 1 expression levels decreased. (5) Human umbilical cord mesenchymal stem cell treatment increased the number of CD31+ microvessels and doublecortin-positive cells after ischemic stroke. …”
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Synergistic potential of bone marrow mesenchymal stem cells and miR181-a combinational therapy against multiple sclerosis by Xin Xiu, Sijia Chen, Yumei Liu, Bo Sun, Hulun Li, Sifan Zhang, Xixi Yang, Yu Wei, Xichen Peng, Yan Wang, Yanping Wang, Junfeng Wu, Yao Zhang, Lili Mu, Qingfei Kong, Xijun Liu

“…Bone marrow mesenchymal stem cells (BMSCs), exhibiting neuroimmune-modulatory functions to alleviate various autoimmune diseases, show great potential in the treatment of MS. …”
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Cord blood therapy for pure red cell aplasia after allogeneic hematopoietic stem cell transplantation: case series and review by Zhen Li, Sujing Zhuang, Ruirui Gui, Binglei Zhang, Wenli Zhang, Juan Wang, Yingling Zu, Fei Yang, Fei Yang, Xiangke Xin, Yanyan Liu, Yanli Zhang, Baijun Fang, Fengkuan Yu, Huifang Zhao, Wei Li, Yongping Song, Yongping Song, Jian Zhou

“…Umbilical cord blood (UCB) and mesenchymal stem cells (MSCs) have been widely used in hematological and immune system diseases due to their hematopoietic reconstitution and immunomodulatory functions. …”
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Bone marrow mesenchymal stem cells transport connexin43 via tunneling nanotubes to alleviate isopreterenol-induced myocardial hypertrophy by Jianghui Zhang, Hongfeng Jiang, Sa Liu, Zhong Xian, Limin Zhao, Yue Li, Wenxiu Lu, Changrong Shao, Sanbao Chai

“…Recently, tunneling nanotubes (TNTs)—a novel type of long-distance intercellular connectional structure—have been identified between mesenchymal stem cells (MSCs) and cardiomyocytes (CMs). TNTs mediate the transmission of multiple signaling molecules, enabling cells to exert different biological functions. …”
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Protective Effects Of Tecomella Undulata Stem Bark Extract On Isoniazid Induced Hepatotoxicity: Based On Liver Enzymes And Histopathology In Rat Model by Zubaida Umar Zehri, Shabih Zehra, Abdul Lateef Mahesar, M. Anwar, Syed Ijaz Hussain Zaidi, M. Ashraf

“… Objective: To evaluate the hepatoprotective effects of Tecomellaundulata stem bark extract on isoniazid induced hepatic damage based on liver enzymes and Liver function test in rat models. …”
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Human placental mesenchymal stem cells ameliorates premature ovarian insufficiency via modulating gut microbiota and suppressing the inflammation in rats. by Shudan Liu, Ting Wang, Yuanyuan Liu, Yiwei Li, Junbai Ma, Qikuan Hu, Hao Wang, Xiaoxia Zhang

“…The core objective of this study was to explore the effects and potential mechanism of human placental mesenchymal stem cells (PMSCs) in improving early-onset ovarian dysfunction (POI). …”
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Therapeutic efficacy of autologous bone marrow mesenchymal stem cell transplantation in patients with spinal cord injury: a meta-analysis by Yulong Liu, Wenbo Xu, Guangchen Liu, Lingli Ma, Zimeng Li

“…Objective: To investigate the efficacy of autologous bone marrow mesenchymal stem cell (BMSC) transplantation in patients with spinal cord injury (SCI) using meta-analysis, aiming to provide evidence-based guidance for clinical practice. …”
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Diversity of endophytic yeast in different varieties of waxy sorghum at flowering period by LIU Wenwen, CHEN Lu, HU Lianqing, FENG Ruizhang, WEI Qin, ZHOU Wanhai, XIANG Qiujin, HUANG Siqi

“…Ascomycota was the dominant phylum in different varieties and the stems and leaves. Basidiomycota was the dominant phylum in flowers, and the dominant phylum in roots was unclassified fungi. …”
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Bladder recovery by stem cell based cell therapy in the bladder dysfunction induced by spinal cord injury: systematic review and meta-analysis. by Jae Heon Kim, Sung Ryul Shim, Seung Whan Doo, Won Jae Yang, Byung Wook Yoo, Joyce Mary Kim, Young Myoung Ko, Eun Seop Song, Ik Sung Lim, Hong Jun Lee, Yun Seob Song

“…The studies were divided into different subgroups by different models of SCI. After a stem cell-based cell therapy, voiding pressure (-6.35, p <0.00001, I2 = 77%), NVC (-3.58, p <0.00001, I2 = 82%), residual urine (-024, p = 0.004, I2 = 95%) showed overall significant improvement. …”
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Human Mesenchymal Stem Cells Derived from the Placenta and Chorion Suppress the Proliferation while Enhancing the Migration of Human Breast Cancer Cells by Sarawut Sirithammajak, Sirikul Manochantr, Chairat Tantrawatpan, Duangrat Tantikanlayaporn, Pakpoom Kheolamai

“…However, hMSCs from different sources may release different combinations of cytokines that affect breast cancer differently. …”
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Adsorption Of Cd(II) Ions From Aqueous Solution By A Low-Cost Biosorbent Prepared From Ipomea Pes-Caprae Stem by Thaharah Ramadhani, Faisal Abdullah, Indra Indra, Abrar Muslim, Suhendrayatna Suhendrayatna, Hesti Meilina, Saiful Saiful

“…The use of a low-cost biosorbent prepared from Ipomoea pes-caprae stem for the adsorption of Cd(II) ions from aqueous solution at different contact times, biosorbent sizes, pH values, and initial Cd(II) ions concentration solution was investigated. …”
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Anti-Inflammatory Potency of Human Wharton’s Jelly Mesenchymal Stem Cell-Derived Exosomes on L2 Cell Line Induced by Lipopolysaccharides by Ika Adhani Sholihah, Anggraini Barlian

“…This study investigated the biological function of normoxic (21% O2 ) vs. hypoxic conditions (5% O2 ) obtained from human Wharton’s Jelly mesenchymal stem cells (hWJ-MSCs) and discovered that exosomes have the ability to suppress inflammatory responses by specifically targeting TNF-α, IL-1β, IL-6. and identify the toll-like receptor 4 (TLR4) NF-κβ gene expression. …”
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Mechanistic insights into adipose-derived stem cells and exosomes in ischemia-reperfusion injury repair: from shared pathways to organ-specific therapeutics by Jiaqian Si, Jie Wang, Hao Dai, Tuochen Lv, Songyun Zhao, Wanying Chen, Liqun Li, Siqi Ding, Yucang He

“…From the perspective of the mechanism interaction network, this paper first proposes a theoretical framework of “multi-organ shared core pathways and dynamic regulation of different targets.” It also reviews the translational potential of combined therapeutic strategies based on engineered exosomes delivery systems and biomaterials, emphasizing the optimization of delivery efficiency and functional enhancement to address the bottleneck of clinical applications. …”
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Hepatocytes derived from human induced pluripotent stem cells: Towards establishing an in vitro model for assessing population variability in hepatotoxicity testing by Xiugong Gao, Rong Li, Kayla Campasino, Miranda R. Yourick, Yang Zhao, Robert L. Sprando, Jeffrey J. Yourick

“…In the current study, we attempted to establish an in vitro model for assessing population variability in hepatotoxicity testing using a panel of hepatocytes derived from nine human induced pluripotent stem cell (iPSC) lines belonging to three different ethnic groups, Black or African American, Latino or Hispanic, and Non-Hispanic White. …”
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