Role of Toll-Like Receptors in Actuating Stem/Progenitor Cell Repair Mechanisms: Different Functions in Different Cells by Fabio Sallustio, Claudia Curci, Alessandra Stasi, Giuseppe De Palma, Chiara Divella, Roberto Gramignoli, Giuseppe Castellano, Anna Gallone, Loreto Gesualdo

“…In this review, we analyze the many different functions that the TLRs assume in SCs, pointing out that they can have different effects, depending on the background and on the kind of ligands that they recognize. …”
Get full text

Sexual development and gonads function in children and adolescents after allogeneic stem cell transplantation using different conditioning regimes by L. I. Papusha, D. N. Balashov, A. N. Tul'pakov, E. V. Skorobogatova, E. E. Kurnikova, Y. V. Skvortsova, A. A. Maschan

Get full text

Immune and Angiogenic Profiling of Mesenchymal Stem Cell Functions in a Subcutaneous Microenvironment for Allogeneic Islet Transplantation by Jocelyn Nikita Campa‐Carranza, Simone Capuani, Ashley L. Joubert, Nathanael Hernandez, Tommaso Bo, Octavio I. Sauceda‐Villanueva, Marzia Conte, Letizia Franco, Marco Farina, Gabrielle E. Rome, Yitian Xu, Junjun Zheng, Lissenya B. Argueta, Jean A. Niles, Fotis Nikolos, Corrine Ying Xuan Chua, Shu‐Hsia Chen, Joan E. Nichols, Norma S. Kenyon, Alessandro Grattoni

“…Importantly, this work discovers sex‐specific differences in both processes, which influence islet engraftment and long‐term function.…”
Get full text

ARAP3 functions in hematopoietic stem cells. by Yiwen Song, Jing Jiang, Sonja Vermeren, Wei Tong

“…Reverse transplantations into VEC-driven Arap3 conditional knockout mice revealed no discernable difference in HSC frequencies or function in comparison to control mice. …”
Get full text

The Effects of Different Factors on the Behavior of Neural Stem Cells by Lixiang Huang, Gan Wang

“…Multiple differentiation potentials of neural stem cell (NSC) determine the application value for the repair of the CNS injury. …”
Get full text

Triple negative breast cancer initiating cell subsets differ in functional and molecular characteristics and in γ‐secretase inhibitor drug responses by Diana J. Azzam, Dekuang Zhao, Jun Sun, Andy J. Minn, Prathibha Ranganathan, Katherine Drews‐Elger, Xiaoqing Han, Manuel Picon‐Ruiz, Candace A. Gilbert, Seth A. Wander, Anthony J. Capobianco, Dorraya El‐Ashry, Joyce M. Slingerland

Get full text

Genetic and Epigenetic Mechanisms That Maintain Hematopoietic Stem Cell Function by Christian Kosan, Maren Godmann

“…Different molecular mechanisms have been identified that are crucial for regulating quiescence and self-renewal to maintain the stem cell pool and for inducing proliferation and lineage differentiation. …”
Get full text

Functionality of endothelial cells differentiated from porcine epiblast stem cells, bone marrow-derived mesenchymal stem cells and adipose-derived mesenchymal stem cells by Yeon-Ji Lee, In-Won Lee, Tae-Suk Kim, Bo-Gyeong Seo, Sang-Ki Baek, Cheol Hwangbo, Joon-Hee Lee

“…The purpose of this study was to induce the differentiation of porcine epiblast stem cells (pEpiSCs), bone marrow-derived mesenchymal stem cells (pBM-MSCs) and adipose-derived mesenchymal stem cells (pA-MSCs) into ECs and then examine the functionality of vascular ECs. …”
Get full text

Functional mechanism on stem cells by tea (Camellia sinensis) bioactive compounds by Yao Cheng, Jiachen Sun, Hui Zhao, Hongxing Guo, Jianying Li

“…The main active ingredients of tea include polyphenols, alkaloids, polysaccharides, amino acids, aroma and volatile constitutes, all of which are potentially responsible for the activities of tea. Stem cells (SCs) are the immature and undifferentiated cells by a varying capacity for proliferation, self-renewal and the capability to differentiate into one or more different derivatives with specialized function or maintain their stem cell phenotype. …”
Get full text

Sub-sets of cancer stem cells differ intrinsically in their patterns of oxygen metabolism. by Luke Gammon, Adrian Biddle, Hannah K Heywood, Anne C Johannessen, Ian C Mackenzie

“…We have recently shown that EMT occurs within the CD44(high) cancer stem cell (CSC) fraction and that epithelial and EMT CSCs are distinguished by high and low ESA expression, respectively. …”
Get full text

ON THE FEATURES OF FUNCTIONING OF LOCAL REFERENCE PREVERBS IN WEST-CAUCASIAN LANGUAGES by A. V. Avidzba

Get full text

Regulation of stem cell fate and function by using bioactive materials with nanoarchitectonics for regenerative medicine by Wei Hu, Jiaming Shi, Wenyan Lv, Xiaofang Jia, Katsuhiko Ariga

“…The different cytoskeletal forces lead to substantial transcription and protein expression, which affect stem cell fate and function. …”
Get full text

Dual Function of Wnt Signaling during Neuronal Differentiation of Mouse Embryonic Stem Cells by Hanjun Kim, Sewoon Kim, Yonghee Song, Wantae Kim, Qi-Long Ying, Eek-hoon Jho

Get full text

Isolation, Culture, and Functional Characterization of Human Embryonic Stem Cells: Current Trends and Challenges by Firdos Alam Khan, Dana Almohazey, Munthar Alomari, Sarah Ameen Almofty

Get full text

Heart Failure Impairs Bone Marrow Hematopoietic Stem Cell Function and Responses to Injury by Tina B. Marvasti, Faisal J. Alibhai, Grace J. Yang, Shu‐Hong Li, Jun Wu, Terrence Yau, Ren‐Ke Li

“…Background Heart failure (HF) is a clinical syndrome associated with a progressive decline in myocardial function and low‐grade systemic inflammation. Chronic inflammation can have lasting effects on the bone marrow (BM) stem cell pool by impacting cell renewal and lineage differentiation. …”
Get full text

Hematopoietic stem cell size heterogeneity is not linked to changes in stem cell potential of aged HSCs by Mehmet Saçma, Ali Hageb, Alex Zadro, Tanja Schuster, Mona Vogel, Karina Eiwen, Vadim Sakk, Hartmut Geiger, Hartmut Geiger

“…Aging is associated with a decline in the function of hematopoietic stem cells (HSCs). This decline in HSC function results in reduced hematologic regenerative capacity and an increased incidence of hematologic disorders. …”
Get full text

Bloodstream infections in different stage of reconstitution after first allogeneic hematopoietic stem cell transplantation by M. I. Akhmedov, G. A. Klyasova, E. N. Parovichnikova, L. A. Kuzmina, A. V. Fedorova, V. A. Vasil’eva, M. Yu. Drokov, S. M. Kulikov, V. G. Savchenko

Get full text

Experimental Strategies of Mesenchymal Stem Cell Propagation: Adverse Events and Potential Risk of Functional Changes by Katarzyna Drela, Luiza Stanaszek, Adam Nowakowski, Zuzanna Kuczynska, Barbara Lukomska

Get full text

Functional heterogeneity of embryonic stem cells revealed through translational amplification of an early endodermal transcript. by Maurice A Canham, Alexei A Sharov, Minoru S H Ko, Joshua M Brickman

Get full text

Iron modulates barrier integrity and stem cell function of small intestine during experimental colitis by Shubin Wang, Xiangjie Yang, Xiangjun Liu, Qin Wen, Lu Xu, Mei Feng, Mei Feng, Jinyi Lang, Dengqun Liu, Dengqun Liu

“…The influence of iron on the barrier integrity and stem cell function was further determined by histology, IEC-6 cell, and enteroid culture. …”
Get full text