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Construction of Diagnostic Model for Regulatory T Cell-Related Genes in Sepsis Based on Machine Learning
Published 2025-04-01“…We then performed both in-ternal and external validation tests. The final diagnostic model was constructed with high diagnostic accuracy (accuracy of 0.9615). …”
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142
Analysis and validation of necroptosis-related diagnostic biomarkers associated with immune infiltration in bronchopulmonary dysplasia
Published 2025-07-01“…Serum ELISA results of PELI1 and PYGL showed no significant difference between BPD and Controls (P > 0.05), the expression level of STAT4 was downregulated in BPD samples (P < 0.05), and the AUC value of the STAT4 was higher than 0.7.ConclusionThe necroptosis-related gene STAT4 can be a diagnostic marker of BPD patients. …”
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143
Identification and validation of TUBB, CLTA, and FBXL5 as potential diagnostic markers of postmenopausal osteoporosis
Published 2025-08-01“…Through the application of SVM, LASSO, and RF algorithms, we identified three potential diagnostic markers: TUBB, CLTA, and FBXL5, which demonstrated promising diagnostic capabilities when tested against an independent dataset. qPCR validation confirmed significant expression differences of these genes between the control and PMOP groups. …”
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144
RETRACTED ARTICLE: Molecular mechanism and diagnostic marker investigation of endoplasmic reticulum stress on periodontitis
Published 2023-03-01“…Two machine learning algorithms were used to reveal potential ERS diagnostic markers of periodontitis. …”
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145
Key gene screening and diagnostic model establishment for acute type a aortic dissection
Published 2025-04-01“…External dataset validation and PCR testing of clinical samples (n = 9) were conducted to confirm gene expression differences. A nomogram diagnostic model was constructed and evaluated for predictive accuracy.ResultsSix core genes were identified: Ccl2, Cdh8, Hk2, Tph1, Npy1r, and Slc24a4, with four (Ccl2, Hk2, Tph1, and Npy1r) showing significant differential expression in clinical validation. …”
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146
Diagnostic and prognostic value of inflammatory indices in patients with prediabetes and type 2 diabetes mellitus
Published 2025-05-01“…Although SIRI did not demonstrate significant between-group differences, it showed a strong correlation with SII in the T2DM group (R = 0.72; p < 0.001). …”
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147
Two-test algorithms for infectious disease diagnosis: Implications for COVID-19.
Published 2022-01-01“…We used a simulation approach to estimate diagnostic outcomes, number of tests required and average turnaround time of using two-test algorithms compared with singular testing; the two tests were reverse transcription polymerase chain reaction (RT-PCR) and an antigen-based rapid diagnostic test (Ag-RDT). …”
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148
Compensation for vibration signal power variance when changing equipment speed mode
Published 2020-09-01“…Vibration power dependencies on the main shaft speed have been estimated in different frequency ranges. The paper proposes an algorithm compensating variations of instantaneous power of vibration signal where equipment operation speed varies. …”
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149
A Highly Discriminative Hybrid Feature Selection Algorithm for Cancer Diagnosis
Published 2022-01-01“…In this article, a machine learning (ML) algorithm is proposed to diagnose different cancer diseases from big data. …”
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150
A simplified treatment algorithm for chronic scrotal content pain syndrome
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151
Clinical performance validation and four diagnostic strategy assessments of high-sensitivity troponin I assays
Published 2025-04-01“…However, there is no consensus on the optimal diagnostic strategy for early NSTEMI detection. This study aims to evaluate the diagnostic performance of four hs-cTnI-based strategies for suspected NSTEMI: Limit of Detection (LoB), Single Cut-off, hs-cTnI 0/1 h Algorithm, and hs-cTnI 0/2 h Algorithm, in a Chinese cohort and compare the performance of assays from different manufacturers. …”
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152
Algorithm-based intraoperative diagnosis of liver tumors using infrared spectroscopy
Published 2025-06-01“…Abstract Liver cancer, including hepatocellular carcinoma (HCC), cholangiocellular carcinoma (CCC), and metastases, presents diagnostic challenges during surgery due to its infiltrative nature. …”
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153
Algorithm for Computationally Efficient Imaging of Sound Speed in Conventional Ultrasound Sonography
Published 2023-10-01“…The algorithm was verified through numerical simulations and phantom measurements. …”
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154
Development and validation of multimodal deep learning algorithms for detecting pulmonary hypertension
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155
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156
A neuro-fuzzy system to support in the diagnostic of epileptic events and non-epileptic events using different fuzzy arithmetical operations Um sistema neuro-difuso para auxiliar n...
Published 2008-06-01“…OBJECTIVE: To investigate different fuzzy arithmetical operations to support in the diagnostic of epileptic events and non epileptic events. …”
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157
Development of Mid-Infrared Spectroscopy (MIR) Diagnostic Model for Udder Health Status of Dairy Cattle
Published 2025-07-01“…Three MIR spectral preprocessing methods, six modeling algorithms, and three different sets of MIR spectral data were employed in various combinations to develop several diagnostic models for mastitis of dairy cattle. …”
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158
Identification and validation of the diagnostic biomarker MFAP5 for CAVD with type 2 diabetes by bioinformatics analysis
Published 2024-12-01“…Next, we intersected the differential genes and module genes of CAVD with the differential genes of diabetes, and the obtained genes were used for subsequent analysis. ML algorithms and the PPI network yielded a total of 12 genes, 10 of which showed a higher diagnostic value. …”
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159
Exploring the relationship between sepsis and Golgi apparatus dysfunction: bioinformatics insights and diagnostic marker discovery
Published 2025-02-01“…Finally, key diagnostic biomarkers were identified and validated across multiple datasets to confirm their diagnostic accuracy.ResultsBy intersecting DEGs, WGCNA modules, and Golgi-related gene sets, 53 overlapping GARGs were identified. …”
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160
Developing a molecular diagnostic model for heatstroke-induced coagulopathy: a proteomics and metabolomics approach
Published 2025-06-01“…Significant differences were observed between the groups in temperature, heart rate, white blood cell count, platelet count, liver function, coagulation markers, APACHE II score, and GCS score. …”
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