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1021
Deciphering the role of cuproptosis in the development of intimal hyperplasia in rat carotid arteries using single cell analysis and machine learning techniques
Published 2025-02-01“…Abstract This study aims to explore the regulatory role of cuproptosis in carotid intimal hyperplasia (IH), providing new insights into its pathophysiological mechanisms and potential diagnostic and therapeutic strategies. Methods: We downloaded single-cell sequencing and bulk transcriptome data from the GEO database to screen for copper-growth-associated genes (CAGs) using machine-learning algorithms, including Random Forest and Support Vector Machine. …”
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1022
SEARCH FOR CLINICAL PREDICTORS OF PULMONARY HYPERTENSION IN PATIENTS WITH SYSTEMIC SCLEROSIS
Published 2018-11-01“…The scope of investigations necessary to detect PH, the complexity of its diagnostic algorithms for routine use, as well as the impossibility to apply the existing algorithms for all PH variants increase the relevance of searching for novel PH predictors in patients with SSc.Objective: to reveal the relationship of capillary structural changes to the clinical and immunological subtype of SSc, disease activity, and risk for PH.Subjects and methods. …”
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1023
Lossy DICOM conversion may affect AI performance
Published 2025-07-01“…So, if DICOM images are intended for a diagnostic use, all processes and algorithms must be (re-)evaluated with the converted files, as images are not identical. …”
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1024
Evolution of deep learning tooth segmentation from CT/CBCT images: a systematic review and meta-analysis
Published 2025-05-01“…Included studies were assessed using the Quality Assessment of Diagnostic Accuracy Study (QUADAS-2) tool. Data were extracted for meta-analyses by random-effects models. …”
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1025
Gut and respiratory microbiota landscapes in IgA nephropathy: a cross-sectional study
Published 2024-12-01“…We applied 16SrRNA sequencing to identify differential microbial populations. ML algorithms were then used to classify IgAN based on these microbial differences. …”
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1026
Chronic Fibrosing Interstitial Lung Disease with Progressive Phenotype
Published 2021-01-01“…Actual achievements in studying fibrosing ILDs which are connected with development of immunology and molecular biological methods for the determination of biomarkers, new principles of image-diagnostics of lung pathology, search of new therapeutic “targets”, dictate the necessity of integration of knowledge by specialists from different areas of medicine for improvement pharmacotherapy algorithms. …”
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1027
Identification of glucocorticoid-related genes in systemic lupus erythematosus using bioinformatics analysis and machine learning.
Published 2025-01-01“…Furthermore, we utilized least absolute shrinkage and selection operator (LASSO) regression and Random Forest (RF) algorithms to screen for hub genes. We then validated the expression of these hub genes and constructed nomograms for further validation. …”
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1028
Point-of-care prognostication in moderate Covid-19: Analytical validation and prognostic accuracy of a soluble urokinase plasminogen activator receptor (suPAR) rapid test.
Published 2023-01-01“…However, most studies evaluating suPAR have used platform-based assays, the accuracy of which may differ from point-of-care tests capable of informing timely triage in settings without established laboratory capacity. …”
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1029
Markers of inflammation as risk predictors of lethal outcome in patients diagnosed with delirium
Published 2016-01-01“…Aiming to better and more precise diagnostics of this complicated and still unclear neuropsychiatric syndrome it would be useful to consider introduction of more precise diagnostic algorithms in every unit of intensive care. …”
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1030
Magnetic resonance imaging relevance in diagnosis and prognosis of early postoperative period following pancreatic cancer surgical treatment
Published 2023-12-01“…Improvement of the prognostic outcomes for the pancreatic fistula development in surgical treatment for pancreatic cancer by implementation of new diagnostic algorithms for magnetic resonance imaging (MRI) assessment of supposed pancreatic stump.Materials and methods. …”
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1031
Breast Tumor-Like-Masses Segmentation From Scattering Images Obtained With an Ultrahigh-Sensitivity Talbot-Lau Interferometer Using Convolutional Neural Networks
Published 2025-01-01“…Segmentation of breast tumors using imaging techniques remains a critical challenge in medical diagnostics, with limitations in contrast and resolution affecting early detection. …”
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1032
TOPICAL ISSUES OF DIAGNOSIS AND TREATMENT OF INFERTILITY IN WOMEN WITH INTERNAL GENITAL ENDOMETRIOSIS
Published 2017-12-01“…Despite the existing methods of diagnosis and treatment of infertility associated with endometriosis, today there is no single algorithm for conducting such a category of patients. …”
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1033
Cross-sectional and longitudinal Biomarker extraction and analysis for multicentre FLAIR brain MRI
Published 2022-06-01“…Biomarkers were extracted from two dementia cohorts (4356 vol, 162 233 images) and one vascular disease cohort (869 vol, 42 850 images) using deep learning-based segmentation algorithms designed specifically for FLAIR. Biomarkers from all cohorts were summarized using descriptive statistics, correlation analysis, and ANCOVA to assess differences in diagnostic labels while accounting for demographic and acquisition factors. …”
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1034
Copper Metabolism-Related Genes as Biomarkers in Colon Adenoma and Cancer
Published 2025-06-01“…Five machine-learning algorithms were employed to identify biomarkers. The degree of immune infiltration was evaluated using single-sample Gene Set Enrichment Analysis (ssGSEA), and the expression profiles of these biomarkers across various cell types were further characterized using single-cell RNA sequencing (scRNA-seq). …”
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1035
Identification and experimental validation of biomarkers associated with mitochondrial and programmed cell death in major depressive disorder
Published 2025-04-01“…Protein-protein interaction (PPI) network analysis and intersection of four algorithms were used to identify key candidate genes. …”
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1036
Gender and age characteristics and atrial fibrillation during long-term telemonitoring of the ECG
Published 2023-12-01“…The primary analysis of the records was carried out using Cardio.ai artificial intelligence algorithms, re-decryption and validation by certified doctors. …”
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1037
In Vivo Insights: Near-Infrared Photon Sampling of Reflectance Spectra from Cranial and Extracranial Sites in Healthy Individuals and Patients with Essential Tremor
Published 2024-10-01“…Our results suggest that NIR spectroscopy, combined with machine learning algorithms, offers a promising non-invasive method for the in vivo characterization and differentiation of tissues in ET patients.…”
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1038
Testicular appendix (hydatid of Morgagni) torsion in adult urological management: evaluation of treatment outcomes
Published 2023-12-01“…To date, there are no systematised data on the long-term results of TAT treatment depending on the diagnostic and therapeutic tactics undertaken. Accordingly, there are no clear algorithms for the management of such patients.Objective. …”
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1039
Machine learning-based brain magnetic resonance imaging radiomics for identifying rapid eye movement sleep behavior disorder in Parkinson’s disease patients
Published 2025-07-01“…Abstract Background Traditional clinical diagnostic methods of rapid eye movement sleep behavior disorder (RBD) have certain limitations, especially in the early stages. …”
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1040
Pulmonary hypertension associated with COPD: a phenotype analysis
Published 2025-03-01“…In the current debate on how to distinguish PH-COPD phenotypes, it might be of interest to include quantitative thresholds for emphysema in future diagnostic and management algorithms.…”
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