Higher Levels of Postoperative Mobility and Activity as Measured by the AM-PAC 6 Clicks Instrument Are Associated with Improved Outcomes after Lumbar Fusion by Parimal Rana, Jane C. Brennan, Andrea H. Johnson, Justin J. Turcotte, Chad M. Patton

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Alterations in functional and structural connectivity in the 6-OHDA-induced Parkinsonian rat model by Shuyi Zhu, Shuyi Zhu, Maurizio Bergamino, Alberto Fuentes, Ivette M. Sandoval, David J. Marmion, Christopher Bishop, Fredric P. Manfredsson, Ashley M. Stokes

“…This study utilized the 6-hydroxydopamine (6-OHDA) rat model to replicate PD-like dopaminergic degeneration through targeted injections into the medial forebrain bundle and substantia nigra.MethodsBehavioral assessments revealed hallmark motor deficits, while MRI was performed to assess complementary functional connectivity and structural connectivity. …”
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Structural and functional insights into the pilotin-secretin complex of the type II secretion system. by Shuang Gu, Saima Rehman, Xiaohui Wang, Vladimir E Shevchik, Richard W Pickersgill

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Neuroimaging differences between chronic migraine with and without medication overuse headache: a 7 Tesla multimodal MRI study by Yin Sun, Longteng Ma, Song Wang, Caohui Duan, Xinyu Wang, Xiangbing Bian, Shuqing Wang, Deqi Zhai, Siyuan Xie, Shuhua Zhang, Yingyuan Liu, Xiaoxue Lin, Ruobing Wang, Xiu Liu, Shengyuan Yu, Xin Lou, Zhao Dong

“…These results highlight the significant impact of medication overuse on brain structure and function, shedding light on the mechanisms of migraine chronification.…”
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Effect of Immunoactive Drugs on Postresuscitation Processes in the Brain and Steroid Hormones by Yu. V. Zarzhetsky, V. V. Moroz, A. V. Volkov

“…Circulation  was  stopped  by  intrathoracic  ligation  of  the  cardiac  vascular  bundle  in  ether<anesthetized  rats  for  10  min. …”
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Computer Simulation of Cardiomyocyte Membrane Exposure to First<Phase Bipolar Defibrillation Impulses by V. A. Vostrikov, B. B. Gorbunov, A. N. Gusev

“…Circulation  was  stopped  by  intrathoracic  ligation  of  the  cardiac  vascular  bundle  in  ether&lt;anesthetized  rats  for  10  min. …”
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White-Matter fiber tract and resting-state functional connectivity abnormalities in young children with autism spectrum disorder by Jia Wang, Natasha Y.S. Kawata, Xuan Cao, Jie Zhang, Takashi X. Fujisawa, Xinyi Zhang, Lili Fan, Wei Xia, Lijie Wu, Akemi Tomoda

“…Furthermore, abnormalities in the structural and functional connectivity index (SFCI) within the SLF and cingulum were identified. …”
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TIME COURSE OF STRUCTURAL AND FUNCTIONAL CHANGES IN THE MYOCARDIAL ARTERIES OF PATIENTS WITH RHEUMATOID ARTHRITIS TREATED WITH METHOTREXATE AND HYDROXYCHLOROQUINE DURING A 4-YEAR F... by A. V. Petrov, A. A. Zayaeva, N. V. Matveeva

“…There is evidence that HC intake has a positive impact on myocardial structural and functional parameters in RA patients.…”
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Surgical approach affecting long-term urinary continence status after robot-assisted laparoscopic prostatectomy prospectively evaluated using self-reported functional status (Expan... by Mathias Reichert, Arne Strauß, Joost Wilhelm Voß, Hans Christoph von Knobloch, Hannah Maria Neuenhofer, Annemarie Uhlig, Lutz Trojan, Mirjam Naomi Mohr

“…Pad usage 12 months after RALP had no significant difference with regard to SR of the neurovascular bundle (p = 0.14). …”
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Structural biomimetics in soft synthetic composite materials: A proof-of-concept alginate-polyamide soft hierarchical composite by M. Sharabi, H. D. Wagner

“…This material system investigates the structure-function relationship between the structure and mechanical function by mimicking different structural motifs. …”
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Effect and Mechanism of Action of Pushing Method on Rats with Skeletal Muscle Overuse Injury based on Wnt/β-catenin Signaling Pathway by DUAN Miaomiao, HUANG Bo, RUAN Lei, MU Pangpang, CHEN Yiming, PENG Liang

“…Catenin protein expression levels.Results(1) Comparison of motor function：compared with the blank group, the time of passing through the balance beam and the number of times of sliding paw were significantly increased in the model group and intervention group after intervention, and the difference was statistically significant (<italic>P</italic>&lt;0.05); compared with the model group, the time of passing through the paw and the number of times of sliding paw were significantly decreased in the intervention group after intervention, and the difference was statistically significant (<italic>P</italic>&lt;0.05). (2) Gastrocnemius muscle histopathological changes：the model group can be seen in the gastrocnemius muscle a large number of myocytes can be seen within the cracks, myogenic fibers fracture; compared with the model group, the degree of damage to the gastrocnemius muscle tissues in the intervention group to reduce the degree of damage, can be seen in the form of myofibers is regular, neatly arranged. (3) Ultrastructural changes in gastrocnemius muscle tissue：local myogenic fiber bundles were broken and dissolved, and a small amount of Z-line structure was dissolved and blurred; compared with the model group, the gastrocnemius muscle cells in the intervention group were slightly edematous, and the structure of the myogenic fiber bundles was clear; part of the myogenic fiber bundles were broken, and the structure of the Z-lines was clear and more neatly arranged. (4) Gastrocnemius muscle tissue MyoD, MyoG and Pax7 mRNA transcript levels：compared with the blank group, MyoD, MyoG and Pax7 mRNA transcript levels were significantly higher in both the model group and the intervention group (<italic>P</italic>&lt;0.05); compared with the model group, MyoD, MyoG and Pax7 mRNA transcript levels were significantly higher in the intervention group (<italic>P</italic>&lt;0.05). (5) Gastrocnemius muscle tissue MyoD, MyoG and Pax7 protein expression level：compared with the blank group, MyoD, MyoG and Pax7 protein expression water were significantly higher in both the model group and the intervention group (<italic>P</italic>&lt;0.05); compared with the model group, MyoD, MyoG and Pax7 protein expression level was significantly higher in the intervention group (<italic>P</italic>&lt;0.05). (6) Wnt3a, Axin2 and β-catenin protein expression levels in gastrocnemius muscle tissues：compared with the blank group, Wnt3a, Axin2 and β-catenin protein expression levels were significantly higher in both the model group and the intervention group (<italic>P</italic>&lt;0.05); compared with the model group, Wnt3a, Axin2 and β-catenin protein expression levels were significantly higher in the intervention group (<italic>P</italic>&lt;0.05).ConclusionPushing method can improve the gastrocnemius muscle injury and motor function in rats with overuse injury model, and its mechanism may be related to the activation of Wnt/β-catenin signaling pathway.…”
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An intelligent hybrid grey wolf-particle swarm optimizer for optimization in complex engineering design problem by Muhammad Suhail Shaikh, Haoyue Lin, Senlin Xie, Xiaoqing Dong, Yifan Lin, Chandan Kumar Shiva, Wulfran Fendzi Mbasso

“…In Case 7, the improvement depends on the bundle configuration, with two-bundle conductors showing a 76.91% increase, three-bundle conductors achieving 43.94%, and four-bundle conductors reaching 46.57%. …”
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Effect and Mechanism of Massage Manipulation on Rats with Skeletal Muscle Overuse Injury Based on Wnt/β-catenin Signaling Pathway by DUAN Miaomiao, HUANG Bo, RUAN Lei, MU Panpan, CHEN Yiming, PENG Liang

“…At 24 h after modeling and 24 h after intervention, the balance beam test was used to assess the motor function of rats with skeletal muscle injury; hematoxylin-eosin (HE) staining method was used to observe the pathological changes of the gastrocnemius muscle; an EM-1400 transmission electron microscope was used to observe the ultrastructure of the skeletal muscle fibers; fluorescence PCR was used to detect the myogenic regulatory factors including myogenic differentiation antigen (MyoD), myogenin (MyoG) and paired box gene 7 (Pax7) mRNA transcript levels; Western blot was used to detect MyoD, MyoG, Pax7, Wnt3a, Axin2 and β-catenin protein expression levels.Results(1) Motor function: compared with the blank group, the time to pass the balance beam and the number of paw slips in the model group and the intervention group increased significantly, and the differences were statistically significant (<italic>P</italic>&lt;0.05). …”
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Spatial Platform for Periodontal Ligament Angulation and Regeneration: In Vivo Pilot Study by Min Guk Kim, Do-Yeon Kim, Hyoung-Gon Ko, Jin-Seok Byun, Joong-Hyun Kim, Chan Ho Park

“…Histological analyses demonstrated that the PDL-guiding architecture regulated fiber orientations and facilitated the functional restoration of PDL bundles in immunohistochemistry with periostin and decorin (DCN). …”
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Loading Patterns of the Posterior Cruciate Ligament in the Healthy Knee: A Systematic Review. by S H Hosseini Nasab, Renate List, Katja Oberhofer, Sandro F Fucentese, Jess G Snedeker, William R Taylor

“…The strain patterns obtained for virtual fibres that connect the origin and insertion of the bundles in a straight line show similar trends to those of the real bundles but with different magnitudes.…”
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Predicting the Electrical Conductivity of Partially Saturated Frozen Porous Media, a Fractal Model for Wide Ranges of Temperature and Salinity by Haoliang Luo, Damien Jougnot, Anne Jost, Jidong Teng, Aida Mendieta, Gang Lin, Luong Duy Thanh

“…In this study, accounting for pore size and tortuous length following fractal distributions, we develop a new capillary bundle model for variation of electrical conductivity as a function of temperature in broad water saturation and salinity ranges. …”
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High posterior tibial slope increases anterior cruciate ligament elongation in unicompartmental knee arthroplasty during early-flexion of lunge by Nan Zheng, Chunjie Xia, Huiyong Dai, Diyang Zou, Yubin Long, Zhiyong Hou, Qi Wang, Tsung-Yuan Tsai

“…In contrast, ACL double-bundle elongations of MB UKA in mid-flexion were larger than contralateral sides (Max-Difference: AM 8.0 ± 8.1%, PL 7.6 ± 9.8%, p < 0.05). …”
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The results of alcohol septal ablation in patients with hypertrophic cardiomiopathy and arterial hypertension by K. V. Rudenko, L. O. Nevmerzhytska, O. Yu. Dudnyk, S. M. Fanta, P. A. Danchenko, I. M. Kurpaianidi, V. V. Lazoryshynets

“…The results of the study showed that comorbid arterial hypertension in patient with obstructive hypertrophic cardiomyopathy who underwent ASA does not affect the short- and long-term parameters of the systolic pressure gradient in left ventricular outflow tract, mitral insufficiency, interventricular septum thickness, NYHA functional class, rate of non-fatal outcomes (complete right-bundle branch block, complete AV-block), mortality.…”
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Towards reconstructing the numeral classifier system of Proto-Tivoid by Michael Terhemen Angitso, Roland Kießling

“…Eventual loss of nominal properties indexes an incipient functional split of the lexical source item and the newly emergent word class of numeral classifier. …”
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Emergence of Xin demarcates a key innovation in heart evolution. by Shaun E Grosskurth, Debashish Bhattacharya, Qinchuan Wang, Jim Jung-Ching Lin

“…In the C-terminus, Xinalphas and Xinbetas are more divergent relative to each other but each isoform from mammals shows a high degree of within-isoform sequence identity. This suggests different but conserved functions for mammalian Xinalpha and Xinbeta. …”
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