Immunomodulatory Activity of Granulocyte Colony-Stimulating Factor and its Therapeutic Effect on Liver Failure by Jinhua Hu, Zijian Sun, Jingjing Tong, Jing Chen, Zifeng Liu, Haijuan Wang

“…Liver failure is characterized by the rapid deterioration of liver function, often accompanied by ascites, coagulation dysfunction, hepatic encephalopathy, and other critical complications. …”
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The impact of clot permeability on platelet fluxes toward its surface. by Niksa Mohammadi Bagheri, Gabor Závodszky, Alfons G Hoekstra

“…This study systematically investigates the transport of platelets, considering the interaction between flow-mediated mass transfer mechanisms and reaction kinetics as a function of clot permeability. A two-dimensional finite element model is developed to replicate static blood flow, platelet transport, and adhesion on a semi-elliptical and semi-circular structure representing permeable clots. …”
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Unravelling the conundrum of nucleolar NR2F1 localization using antibody-based approaches in vitro and in vivo by Michele Bertacchi, Susanne Theiß, Ayat Ahmed, Michael Eibl, Agnès Loubat, Gwendoline Maharaux, Wanchana Phromkrasae, Krittalak Chakrabandhu, Aylin Camgöz, Marco Antonaci, Christian Patrick Schaaf, Michèle Studer, Magdalena Laugsch

“…Hence, we studied this phenomenon employing various in vitro and in vivo models using different antibody-dependent approaches. Examination of seven commonly used anti-NR2F1 antibodies in different human cancer and stem cells as well as in wild type and null mice revealed that NR2F1 nucleolar localization is artificial and has no functional role. …”
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The influence of 6-Benzylaminopurine (BAP) on yield responses and photosynthetic physiological indices of soybean by Xinglong Lian, Shuang Liu, Aatika Sikandar, Zongli Kang, Yaxing Feng, Lanyuwen Jiang, Yuanyuan Wang

“…In the current investigation, spraying different concentrations of BAP had no significant effect on the soybean yield. …”
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Autonomic dysfunction in multiple system atrophy: from pathophysiology to clinical manifestations by Yuqi Luo, Nan Yang, Wanlin Yang, Baoling Chen, Shuzhen Zhu, YihRu Wu, Qing Wang

“…The deposition of α-synuclein in highly interconnected neuronal networks with different neurochemistry properties in different regions of the cortex, diencephalon, brain stem and spinal cord leads to early onset and extensive autonomic dysfunction in MSA. …”
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Overcoming the resistance of hepatocellular carcinoma to PD-1/PD-L1 inhibitor and the resultant immunosuppression by CD38 siRNA-loaded extracellular vesicles by Jun Deng, Hui Ke

“…Loss-of-function assays were conducted to investigate the biological functions of EVs/siCD38 in HCC cells. …”
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Qualitative study exploring the key determinants of information gathering to inform the management of over-the-counter (OTC) consultations in community pharmacies by Rumana Newlands, Heather Cassie, Eilidh M Duncan, Elizabeth A Gibb, Ailsa Power, Linda Young, Mags C Watson

“…This study highlights the importance of tailoring interventions to reflect different roles, functions and responsibilities of community pharmacy personnel.…”
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Prediction of Soil Carbon Sequestration in Rangelands Regarding the Depth and Elevation of Sample Locations using Adaptive Neuro-Fuzzy Inference System (ANFIS) (Case Study: Lar Wat... by zeinab jafarian, zhila ghorbani

“…With a statistical climate period of 36 years, it is a semi-humid to ultra-cold region where the average rainfall is 550 mm. …”
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Urban Retail in Inland Abruzzo: Between Decline and New Polarities by Bernardo Cardinale, Dante Di Matteo, Concettina Pascetta, Luca Zarrilli

“…Availing of descriptive and semi-parametric approaches, we found that some public policies, like subsides and pedestrianisation, had an impact on retailers’ perception based in inland areas even higher than those localised in coastal areas, while other features still remain lacking, such as accessibility; besides, compared with coastal areas, consumers’ perceptions in inland areas show an higher social function, where buying behavior is less hedonic and more functional to the needs of local communities.…”
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Accelerating cartilage regeneration with DNA-SF hydrogel sustained release system-based cartilage organoids by Cong-Yi Shen, Qi-Rong Zhou, Xiang Wu, Xin-Yu Han, Qin Zhang, Xiao Chen, Yu-Xiao Lai, Long Bai, Ying-Ying Jing, Jian-Hua Wang, Cheng-Long Wang, Zhen Geng, Jia-Can Su

“…Organoids, miniature three-dimensional (3D) tissue structures derived from the directed differentiation of stem or progenitor cells, mimic the structure and function of natural organs. …”
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Expanding the Role of FurA as Essential Global Regulator in Cyanobacteria. by Andrés González, M Teresa Bes, M Luisa Peleato, María F Fillat

“…The results of such approaches led us to identify 15 novel direct iron-dependent transcriptional targets belonging to different functional categories including detoxification and defences against oxidative stress, phycobilisome degradation, chlorophyll catabolism and programmed cell death, light sensing and response, heterocyst differentiation, exopolysaccharide biosynthesis, among others. …”
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Global Transcriptome and Correlation Analysis Reveal Cultivar-Specific Molecular Signatures Associated with Fruit Development and Fatty Acid Determination in Camellia oleifera Abel by Shaofeng Peng, Jia Lu, Zhen Zhang, Li Ma, Caixia Liu, Yongzhong Chen

“…The transcriptomics was conducted to perform a comprehensive and system-level view on dynamic gene expression networks for different developmental stages. Short Time-series Expression Miner (STEM) analysis of XL106 (the 6 time points) and XL210 (8 time points) was performed to screen related fatty acid (FA) gene set, from which 1041 candidate genes related to FA were selected in XL106 and 202 related genes were screened in XL210 based on GO and KEGG enrichment. …”
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How short peptides interact with oral cells? A systematic review by Giulia Tetè, Aleksandr Trofimov, Natasha Cinta Vinskid, Giuseppe Tafuri, Fabia Profili, Bruna Sinjari

“…Results 8 in vitro studies dealing with different short peptides with different biological functions against oral cavity cells and tissues were included. 4 articles highlighted the ability of short peptides to positively influence the proliferation of cells in the oral cavity. 2 articles highlighted the antitumour activity of short peptides. 1 article highlighted the antimicrobial activity of the peptide DJK-15. …”
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Effects of PPARγ Ligands on Leukemia by Yoko Tabe, Marina Konopleva, Michael Andreeff, Akimichi Ohsaka

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Neutrophils: The Gatekeepers to Candidal Infection by Aliyu, M. , Muhammed, Y. , Azeez-Akande, O. and Jibril, M.*

“…Subpopulations of PMNs exist in different tissues carrying specialized functions. Understanding the various roles of PMN in candidiasis can aid in the development of immunotherapy as the current antifungal therapy recorded a colossal setback.…”
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CHD1 contributes to intestinal resistance against infection by P. aeruginosa in Drosophila melanogaster. by Johanna Sebald, Stefano Morettini, Valerie Podhraski, Cornelia Lass-Flörl, Alexandra Lusser

“…We found a fraction of genes that were misregulated in Chd1 mutants to be functionally linked to Drosophila immune and stress response. …”
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A novel heuristic Morlet wavelet neural network design for the painlevé equation-II arising in nonlinear optics by Sundas Faisal, Zulqurnain Sabir, Samra Urooj Khan, Muhammad Aamir, Krzysztof A. Cyran

“…Moreover, the statistical analysis using the multiple independent runs is performed by different tests including Theil’s inequality coefficient, variance account for and semi inter-quartile range, which shows the dependability of the proposed MWNN-GA-IPA in order to Painlevé equation-II arising in nonlinear optics. …”
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Aircraft Bearing Fault Diagnosis Method Based on LSTM-IDRSN by Lei Wang, Kun He, Haipeng Fu, Weixing Chen

“…A fully connected layer with a SoftMax activation function is then used to classify faults in the training set. …”
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Silencing NEDD4L Effectively Inhibits the Malignant Behaviors of Hepatocellular Carcinoma by Dai J, Zhu T, Wan J, Liu R, Song Y, Zhang D, Wang X, Zhang H, Li W, Lin J, Zhu X, Liu Y

“…Single-cell sequencing analysis revealed that NEDD4L was notably enriched in cancer stem cell populations across different HCC developmental stages and immune states, with subgroups exhibiting high NEDD4L expression sharing substantial co-expressed genes with stem cell subpopulations. …”
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Dynamics of hydrogen-bonded end groups in bulk polymers revealed by solid-state NMR spectroscopy relaxation dispersion experiments by Sophia Thiele, Christopher J. G. Plummer, Laura Piveteau, Holger Frauenrath

“…We have successfully determined the timescale of end-group dissociation directly and independently of any relaxation of the polymer segments at different temperatures in the bulk semi-crystalline and melt state. …”
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