Cancer stem cells: The potential role of autophagy, proteolysis, and cathepsins in glioblastoma stem cells by Joachim Bischof, Mike-Andrew Westhoff, Johanna Elisabeth Wagner, Marc-Eric Halatsch, Stephanie Trentmann, Uwe Knippschild, Christian Rainer Wirtz, Timo Burster

“…In case of immune recognition, several survival mechanisms including, regulation of autophagy, proteases, and cell surface major histocompatibility complex class I molecules, are found in glioblastoma stem cells. In different pathways, cathepsins play a crucial role in processing functional proteins that are necessary for several processes and proper cell function. …”
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The immunology of corneal limbal stem cells: the up-to-date approach to stem cell transplantation by Katarzyna Samelska, Magdalena Kupis, Katarzyna Szymanek, Justyna Izdebska, Anna Zaleska-Żmijewska, Piotr Skopiński

“…There are different types of stem cell grafting including cultivated limbal epithelial transplantation (CET) and simple limbal epithelial transplantation (SLET). …”
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Evolution of the Soil Bacterial Community as a Function of Crop Management: A Metagenomic Study in Orange Tree (<i>Citrus sinensis</i>) Plantations by Carlos Giménez-Valero, Alejandro Andy Maciá-Vázquez, Dámaris Núñez-Gómez, Agustín Conesa, Vicente Lidón, Pablo Melgarejo

“…Soil management significantly influences the structure and diversity of soil bacterial communities, affecting biodiversity and ecosystem functions. In semi-arid regions, water efficiency strategies like anti-weed netting are implemented, but their impact on soil microbial communities remains underexplored. …”
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Functional heterogeneity of mesenchymal stem cells and their therapeutic potential in the K18-hACE2 mouse model of SARS-CoV-2 infection by Kátia Nunes da Silva, Fernanda Martins Marim, Gisele Vieira Rocha, Zaquer Suzana Munhoz Costa-Ferro, Luciana Souza de Aragão França, Carolina Kymie Vasques Nonaka, Bruno Diaz Paredes, Erik Aranha Rossi, Erick Correia Loiola, Corynne Stephanie Ahouefa Adanho, Rachel Santana Cunha, Mayck Medeiros Amaral da Silva, Fernanda Ferreira Cruz, Vivian Vasconcelos Costa, Dalila Lucíola Zanette, Clarissa Araújo Gurgel Rocha, Renato Santana Aguiar, Patricia Rieken Macedo Rocco, Bruno Solano de Freitas Souza

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Adipose-derived mesenchymal stem cell-supported ciprofloxacin therapy effectively protects the kidney parenchyma and functional integrity against acute pyelonephritis damage in rod... by Chih-Chao Yang, Ya Yue, Pei-Lin Shao, Ben-Chung Cheng, Tsuen-Wei Hsu, Yi-Ling Chen, Sheung-Fat Ko, Hon-Kan Yip, Mel S. Lee

“…This study revealed that adipose-derived mesenchymal stem cell-facilitated ciprofloxacin therapy effectively protected the kidney parenchyma and functional integrity against acute pyelonephritis damage in rodents. …”
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Comparative Analysis of Short-Term and Long-Term Clinical Efficacy of Mesenchymal Stem Cells from Different Sources in Knee Osteoarthritis: A Network Meta-Analysis by Qi Xin Ding, Xu Wang, Tian Shu Li, Yue Fang Li, Wan Yue Li, Jia Huan Gao, Yu Rong Liu, WeiSheng Zhuang

“…A meta-analysis revealed that different sources of MSCs improved knee function and pain more effectively among patients suffering from knee OA (KOA) than controls. …”
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Segmentation Studies on Al‐Si‐Mg Metallographic Images Using Various Different Deep Learning Algorithms and Loss Functions by Abeyram M. Nithin, Murukessan Perumal, M. J. Davidson, M. Srinivas, C. S. P. Rao, Katika Harikrishna, Jayant Jagtap, Abhijit Bhowmik, A. Johnson Santhosh

“…Additional comparisons have been made using the Dice score (0.85), IOU score (0.74), F1 (0.85), and recall (0.96) measures. Different loss functions were also compared, including binary, SS loss, and Tversky. …”
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Neurotechnology for enhancing human operation of robotic and semi-autonomous systems by William J. Tyler, William J. Tyler, Anusha Adavikottu, Christian Lopez Blanco, Archana Mysore, Archana Mysore, Christopher Blais, Marco Santello, Avinash Unnikrishnan

“…Human operators of remote and semi-autonomous systems must have a high level of executive function to safely and efficiently conduct operations. …”
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CACNA1A loss-of-function affects neurogenesis in human iPSC-derived neural models by Ilaria Musante, Davide Cangelosi, Lorenzo Muzzi, Fanny Jaudon, Marco Di Duca, Sara Guerrisi, Francesca Antonini, Yeraldin Chiquinquira Castillo De Spelorzi, Lorenzo A. Cingolani, Federico Zara, Paolo Scudieri

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Semi-Automated PCR Method for Quantitating MDR1 Expression by S. Zhao, U. Consoli, R. Arceci, J. Pfeifer, W.S. Dalton, M. Andreeff

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Mesenchymal stem cells: diversity by O. M. Grabovyi, N. M. Nevmerzhytska, L. M. Yaremenko, H. B. Kostynskyi, A. S. Demydchuk, H. Yu. Kondaurova

“…However, some cells at different stages of histogenesis leave it. Such resident cells in tissues are stem cells. …”
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Prepatterning in the stem cell compartment. by Peter D Tonge, Victor Olariu, Daniel Coca, Visakan Kadirkamanathan, Kelly E Burrell, Stephen A Billings, Peter W Andrews

“…Our results suggest that pluripotent NTERA2 stem cells oscillate between functionally distinct substates that are primed to select distinct lineages when differentiation is induced.…”
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Tenogenic Cues Are Biochemically and Environmentally Distinct for Tendon Stem Cells and Mesenchymal/Stromal Stem Cells by Vera Citro, Marta Clerici, Giovanna Della Porta, Nicola Maffulli, Aldo R. Boccaccini, Tina P. Dale, Nicholas R. Forsyth

“…Tendons’ inherent limited regenerative capacity often hinders complete recovery from injuries, leading to chronic conditions and impaired functionality. Autologous mesenchymal/stromal stem cells (MSCs) and tendon-derived stem cells (TSCs), combined with growth factors (GFs) like GDF-5, GDF-6 and GDF-7, are emerging as potential therapies for tendinopathy. …”
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Clinical impacts of total parenteral nutrition in hematopoietic stem cell transplantation patients with high nutritional risk by Le Yang, Di Wu, Junting Dai, Huiyi Lv, Miao Li

“…In addition, there were no significant differences in CRBSI incidence or liver function between the non-TPN and TPN groups. …”
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Understanding family functioning in mothers and daughters with obesity by Becky Marquez, Florencia Lebensohn-Chialvo, Tala Al-Rousan

“…Methods Semi-structured in-depth interviews were conducted with mothers and adult daughters (N = 116). …”
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Differences in neuronal ciliation rate and ciliary content revealed by systematic imaging-based analysis of hiPSC-derived models across protocols by Walther Haenseler, Melanie Eschment, Melanie Eschment, Beth Evans, Marta Brasili, Marta Brasili, Joana Figueiro-Silva, Fee Roethlisberger, Fee Roethlisberger, Affef Abidi, Affef Abidi, Darcie Jackson, Martin Müller, Martin Müller, Sally A. Cowley, Ruxandra Bachmann-Gagescu, Ruxandra Bachmann-Gagescu, Ruxandra Bachmann-Gagescu, Ruxandra Bachmann-Gagescu

“…Patient derived- or genetically engineered human induced pluripotent stem cells (hiPSCs) are therefore a precious resource for investigating the role of cilia in human neurons.MethodsIn this study we used a variety of 2D and 3D neuronal differentiation protocols in multiple hiPSC lines and systematically analyzed ciliation rates and ciliary length in hiPSCs, neural stem cells (NSCs), immature and different types of mature neurons using immunofluorescence.ResultsWe found that ciliation rate varied substantially between cell lines and differentiation protocols. …”
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Machine learning-based characterization of stemness features and construction of a stemness subtype classifier for bladder cancer by Heping Qiu, Xiaolin Deng, Jing Zha, Lihua Wu, Haonan Liu, Yichen Lu, Xinji Zhang

“…We calculated the mRNA expression-based stemness index (mRNAsi) using the OCLR algorithm. We compared the differences in overall survival, genomic characteristics, tumor microenvironment, and treatment response between the stemness subtypes. …”
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Non-uniform Porosity Distribution on a Hollow Cylinder with Thermo-magnetic Mechanical Loading by Rania Tantawy, Mohammed Alghamdi, Ashraf Zenkour

“…Currently, with the tremendous development in manufacturing composite materials, porous functionally graded materials have attracted many engineering, thermal, and electrical studies and applications on porous structures as most recent applications in functionally graded (FG) materials. …”
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Dimuons from neutrino-nucleus collisions in the semi-inclusive DIS approach by Ilkka Helenius, Hannu Paukkunen, Sami Yrjänheikki

“…Here, we instead compute the dimuon production cross section directly as a convolution of semi-inclusive deep inelastic scattering to produce charmed hadrons, and a decay function fitted to e + e − data to produce a muon from the charmed hadrons. …”
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Functional analysis of JPH2-knockout cardiomyocytes identifies ECCD as a novel indicator in a human cardiac modelJPH2 by Tianwei Guo, Hongyue Wang, Fujian Wu, Wenjing Lu, Min Zhu, Shuhong Ma, Yongshuai Zhang, Yuting Yan, Meng Zhou, Didaer Talanaite, Siyu Liu, Man Qi, Feng Lan, Xujie Liu

“…This study aimed to investigate JPH2’s role in human cardiac function and disease using a novel stem cell-derived model, while introducing a new indicator to evaluate related cardiac impairments. …”
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