Intrathecal Infusion of Autologous Adipose-Derived Regenerative Cells in Autoimmune Refractory Epilepsy: Evaluation of Safety and Efficacy by Elzbieta Szczepanik, Hanna Mierzewska, Dorota Antczak-Marach, Anna Figiel-Dabrowska, Iwona Terczynska, Jolanta Tryfon, Natalia Krzesniak, Bartlomiej Henryk Noszczyk, Ewa Sawicka, Krystyna Domanska-Janik, Anna Sarnowska

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Preparation of Zinc-Doped Hydroxyapatite Ceramics and Evaluation of Biocompatibility and Antibacterial Activity by José R. Guerra-López, Ana E. Bianchi, Marcelo A. Ramos, Mauro Ubertino, Verónica Ferraresi-Curotto, Jorge A. Güida, Katia Barbaro, Anna A. Zhukova, Victoria Yu. Grigorieva, Julietta V. Rau, Gustavo A. Echeverría

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Characterization of Human Knee and Chin Adipose-Derived Stromal Cells by Magali Kouidhi, Phi Villageois, Carine M. Mounier, Corinne Ménigot, Yves Rival, David Piwnica, Jérôme Aubert, Bérengère Chignon-Sicard, Christian Dani

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A Novel Molecular Classification Method for Glioblastoma Based on Tumor Cell Differentiation Trajectories by Guanghao Zhang, Xiaolong Xu, Luojiang Zhu, Sisi Li, Rundong Chen, Nan Lv, Zifu Li, Jing Wang, Qiang Li, Wang Zhou, Pengfei Yang, Jianmin Liu

“…Each cluster exhibited different potential drug sensitivities, pathways, functions, and transcriptional modules. …”
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Fabrication and Characterization of Alveolus-Like Scaffolds with Control of the Pore Architecture and Gas Permeability by Lanxin Lü, Hongxian Shen, Daichi Kasai, Ying Yang

“…The cellular response of the scaffolds was assessed by culturing with bone marrow mesenchymal stem cells and coculturing with lung epithelial NL20 and endothelial HUVECs. …”
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Metformin Inhibits the Expression of Biomarkers of Fibrosis of EPCs In Vitro by Fei Han, Jie Shu, Shunjun Wang, Can-e Tang, Fanyan Luo

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Tissue Engineering for Rotator Cuff Repair: An Evidence-Based Systematic Review by Nicola Maffulli, Umile Giuseppe Longo, Mattia Loppini, Alessandra Berton, Filippo Spiezia, Vincenzo Denaro

“…The three studies found no difference in clinical rating scales and functional outcomes between PRP and control groups. …”
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CD14 and ALPK1 Affect Expression of Tight Junction Components and Proinflammatory Mediators upon Bacterial Stimulation in a Colonic 3D Organoid Model by Pascal Brooks, Talke zur Bruegge, Erin C. Boyle, Stefan Kalies, Santiago Nahuel Villarreal, Andrea Liese, André Bleich, Manuela Buettner

“…Intestinal barrier integrity can be influenced by CD14, whereas to date, the role of ALPK1 in maintaining barrier function remains unknown. We used colon-derived 3D organoids, first characterised for growth, proliferation, stem cell markers, and expression of tight junction (TJ) components using qPCR and immunohistochemistry. …”
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The Regulatory Role of Ferroptosis in Bone Homeostasis by Yuan Xiong, Lang Chen, Ze Lin, Yiqiang Hu, Adriana C. Panayi, Wu Zhou, Yun Sun, Faqi Cao, Guodong Liu, Guangdong Dai, Bobin Mi, Guohui Liu

“…Herein, we review and discuss recent studies exploring the mechanisms and functions of ferroptosis in different bone-related cells, including mesenchymal stem cells, osteoblasts, osteoclasts, and osteocytes. …”
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The Role of Fibroblast Growth Factors in Tooth Development and Incisor Renewal by Wen Du, Wei Du, Haiyang Yu

“…This review discusses the role of FGF signaling in these mineralized tissues, trying to separate its different functions and highlighting the crosstalk between FGFs and other signaling pathways.…”
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Stimuli-Responsive Graphene Nanohybrids for Biomedical Applications by Dinesh K. Patel, Yu-Ri Seo, Ki-Taek Lim

“…Numerous surface functionalizations are possible for the graphene structure with different functional groups, which can be used to alter the properties of native materials. …”
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Cell Connections by Tunneling Nanotubes: Effects of Mitochondrial Trafficking on Target Cell Metabolism, Homeostasis, and Response to Therapy by Marie-Luce Vignais, Andrés Caicedo, Jean-Marc Brondello, Christian Jorgensen

“…TNTs allow the cell-to-cell transfer of various cellular components, including proteins, RNAs, viruses, and organelles, such as mitochondria. Mesenchymal stem cells (MSCs) are both naturally present and recruited to many different tissues where their interaction with resident cells via secreted factors has been largely documented. …”
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Advances in MicroRNA-Mediated Reprogramming Technology by Chih-Hao Kuo, Shao-Yao Ying

“…Soon after the discovery of embryonic-stem-cell- (ESC-) specific miRNAs, researchers began to investigate their functions in embryonic development and differentiation, as well as their potential roles in somatic cell reprogramming (SCR). …”
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Vessel Wall-Derived Mesenchymal Stromal Cells Share Similar Differentiation Potential and Immunomodulatory Properties with Bone Marrow-Derived Stromal Cells by Zoltán Veréb, Anett Mázló, Attila Szabó, Szilárd Póliska, Attila Kiss, Krisztina Litauszky, Gábor Koncz, Zoltán Boda, Éva Rajnavölgyi, Attila Bácsi

“…For comparative analysis, the expression of different stemness, proliferation, and differentiation-related genes was determined by Affymetrix gene array. …”
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Extracellular Vesicles from MSC Modulate the Immune Response to Renal Allografts in a MHC Disparate Rat Model by M. Koch, A. Lemke, C. Lange

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Exosomes for Intramyocardial Intercellular Communication by Elisabetta Cervio, Lucio Barile, Tiziano Moccetti, Giuseppe Vassalli

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Generation of hiPSC lines with fusion tagged thyroid hormone receptor α isoforms to study isoform-specific actions of TRα1 and TRα2 by Nina Härting, Katarzyna A. Ludwik, Regina Jahn, Frank J. Kaiser, Harald Stachelscheid

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Role of Primary Cilia in Skeletal Disorders by Xinhua Li, Song Guo, Yang Su, Jiawei Lu, Donghua Hang, Shao Cao, Qiang Fu, Ziqing Li

“…In addition, the intact of primary cilium is essential to osteogenic/chondrogenic induction of mesenchymal stem cells, regarded as a promising target for clinical intervention for skeletal disorders. …”
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Endothelial Plasticity: Shifting Phenotypes through Force Feedback by Guido Krenning, Valerio G. Barauna, José E. Krieger, Martin C. Harmsen, Jan-Renier A. J. Moonen

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Genome Editing Redefines Precision Medicine in the Cardiovascular Field by Elda Dzilic, Harald Lahm, Martina Dreßen, Marcus-André Deutsch, Rüdiger Lange, Sean M. Wu, Markus Krane, Stefanie A. Doppler

“…In this review, we focus on the achievements and limitations of genome editing in the cardiovascular field. We explore different areas of cardiac research and highlight the most important developments: (1) the potential of genome editing in human pluripotent stem cells in basic research for disease modelling, drug screening, or reprogramming approaches and (2) the potential and remaining challenges of genome editing for regenerative therapies. …”
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