Identification of functional pathways and hub genes associated with the heterochronic development of sugarcane axillary buds and sett roots through multi-omics analysis by Jiabao Zheng, Xiaoyu Huang, Yanli Wei, Wenyan Li, Baoshan Chen, Baoshan Chen, Wenlan Li, Wenlan Li

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Hypomethylation of GCNT2 isoform A correlates with transcriptional expression and is associated with poor survival in acute myeloid leukemia by De-hong Wu, De-hong Wu, Hong-chun Qiu, Jing Xu, Jiang Lin, Jun Qian

“…BackgroundThe function of GCNT2 has been documented to act as an oncogenic driver or tumor suppressor in different types of tumor, but the role of GCNT2 and the epigenetic regulation mechanism in AML, however, has not yet been clarified. …”
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The ‘process of doing’ in everyday occupations – a challenge for young adults with cerebral palsy by L. Bergqvist, A. M. Öhrvall, M. Peny-Dahlstrand

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Sequential simulation of regeneration-specific microenvironments using scaffolds loaded with nanoplatelet vesicles enhances bone regeneration by Wenshuai Li, Qichen Shen, Tong Tong, Hongsen Tian, Xiaowei Lian, Haoli Wang, Ke Yang, Zhanqiu Dai, Yijun Li, Xianhua Chen, Qingqing Wang, Dan Yang, Feng Wang, Feng Hao, Linfeng Wang

“…In vitro, the NPVs regulated lipid metabolism in bone marrow mesenchymal stem cells (BMSCs), reprogramed the fate of BMSCs by activating the PI3K/AKT and MAPK/ERK positive feedback pathways, and increased BMSC functions, including proliferation, migration and proangiogenic potential. …”
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Aberrant white matter and subcortical gray matter functional network connectivity associated with static and dynamic characteristics in subjects with temporal lobe epilepsy by Sukesh Kumar Das, George B. Hanna, Hai Sun, Bharat B. Biswal

“…This altered connectivity categorizes TLE as a network disorder, highlighting the need to investigate functional network connectivity (FNC) in WM areas. Dynamic functional connectivity (dFC) measures time-varying correlations between two or multiple regions of interest and derives clusters highlighting functional networks (FNs) where connectivity among regions behaves in a similar fashion. …”
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Phosphoinositide Signaling and Actin Polymerization Are Critical for Tip Growth in the Marine Red Alga <i>Pyropia yezoensis</i> by Ryunosuke Irie, Koji Mikami

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Structural and functional alterations of neurons derived from sporadic Alzheimer’s disease hiPSCs are associated with downregulation of the LIMK1-cofilin axis by Raimondo Sollazzo, Domenica Donatella Li Puma, Giuseppe Aceto, Fabiola Paciello, Claudia Colussi, Maria Gabriella Vita, Guido Maria Giuffrè, Francesco Pastore, Alessia Casamassa, Jessica Rosati, Agnese Novelli, Sabrina Maietta, Francesco Danilo Tiziano, Camillo Marra, Cristian Ripoli, Claudio Grassi

“…Results sAD and HS hiPSCs displayed similar stemness features and genomic stability. However, they differed in neuronal differentiation and function. sAD-derived neurons (sAD-hNs) displayed increased levels of AD-related proteins, including Aβ and phosphorylated tau. …”
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In vitro comparison of naturally bioactive plant extracts, essential oils, and marine algae targeting different modes of action for mitigation of enteric methane emissions in rumin... by Ian Hodge, Ian Hodge, Patrick Quille, Manimaran Ayyachamy, Shane O'Connell, Shane O'Connell

“…Feed additives altering rumen microbial populations by reducing methanogens and promoting VFA production increase readily available energy for the animal while reducing CH4 generation significantly. Semi-continuous rumen culture fermentations or in vivo studies can confirm the long-term stability of synergistic antimethanogenic mechanisms, potentially optimizing CH4 inhibitors like A. taxi and EO for commercial use.…”
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Generic Models of Willow (genus Salix L.) Tree Phytomass: a Meta-Analysis by Andrey А. Paramonov, Vladimir A. Usoltsev, Sergey V. Tretyakov, Ilya V. Tsvetkov, Ivan S. Tsepordey

“…In the course of the work, the models have been constructed for assessing the aboveground phytomass of trees both in diameter at the stem base and in diameter at breast height, the information content of which is close to functional, and the biases are only about 2 %. …”
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Aerobic-Resistance Training with Royal Jelly Supplementation Has a Synergistic Effect on Paraoxonase 1 Changes and Liver Function in Women with MASLD by Roya Askari, Nazanin Rabani, Hamid Marefati, Marzie Sadat Azarnive, Matteo Pusceddu, Gian Mario Migliaccio

“…<i>Materials and Methods</i>: This semi-experimental study involved 23 women with Dysfunction-Associated Steatotic Liver Disease with an average weight (71.34 ± 11.63 kg), age (48.54 ± 3.88 years), and body mass index (27.63 ± 4.20 kg/m²). …”
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Effects of <i>Caragana korshinskii</i> aqueous extract on growth performance, antioxidant capacity, and immune function of sheep under cold stimulation by B. Pan, J. Yang, J. Li, M. Xu, M. Yang, M. Yang, M. Peng, J. Cheng, S. Xue, J. Wang

“…<p>Cold stimulation can impair the immune and antioxidant functions of animals, which further leads to a decline in animal production performance. …”
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Injectable elastin-like recombinamer hydrogels with layered degradation rates for osteochondral regeneration in a rabbit model by Desiré Venegas-Bustos, Gonzalo Martínez-Municio, S. Martínez-Páramo, Israel González de Torre, F. Lamus, M.I. Alonso, A. Gato, A.J. Álvarez-Barcia, A. Vega-Castrillo, Mercedes Alberca, J.C. Rodríguez-Cabello

“…The regeneration of osteochondral defects remains a significant challenge due to the distinct structural and functional requirements of cartilage and subchondral bone. …”
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Temperature Dependences of the Electron Energy in AlxGa1 – xAs / GaAs / AlxGa1 – xAs Nanofilms of Different Thickness and Composition of the Barrier Material by D.V. Kondryuk, V.M. Kramar

“…Temperature dependences of the energy of electron ground state in AlxGa1 – xAs / GaAs / AlxGa1 – xAs nanofilms of different thickness and concentrations (x) of the barrier material were calculated. …”
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Functional outcome, revision rates and mortality after primary total hip replacement--a national comparison of nine prosthesis brands in England. by Mark Pennington, Richard Grieve, Nick Black, Jan H van der Meulen

“…<h4>Conclusions</h4>Functional outcomes were better with cementless cups and revision rates were lower with cemented stems, which underlies the good overall performance of hybrids. …”
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Phenotypic and transcriptomic analysis reveals key genes associated with plant height in rubber tree and functional characterization of the candidate gene HbFLA11 by Baoyi Yang, Yuanyuan Zhang, Weiguo Li, Xiao Huang, Xinsheng Gao, Juncang Qi, Xiangjun Wang

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Decoupling and Insensitivity of Greenness and Gross Primary Productivity Across Aridity Gradients in China by Yuzhen Li, Xiuliang Yuan, Lei Zheng, Wenqiang Zhang, Yue Zhang

“…For different plant functional types (PFTs), decoupling occurred in ENF with a determination coefficient value (R²) of 0.04, whereas GRA shows a higher coupling with an R² of 0.20. …”
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Warning in the woods: Species-specific and functional responses of the understorey along a deer browsing intensity gradient in a mixed temperate forest in France by Xavier Lecomte, Christophe Baltzinger, Anders Mårell

“…The study aims to explore the effects of deer browsing and grazing intensity, estimated through a browsing index on woody and semi-woody plants, on understorey vegetation composition, analysing both taxonomic and functional diversity. …”
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Cloning and Functional Analysis of Flavonol Synthase Gene <i>ZjFLS</i> from Chinese Jujube (<i>Ziziphus jujuba</i> Mill.) by Xiaofang Xue, Ailing Zhao, Le Fu, Yongkang Wang, Haiyan Ren, Wanlong Su, Meijuan Shi, Li Liu, Yi Li, Dengke Li

“…Within these expression levels, it was higher in young leaves than in mature leaves and higher in the white-ripe-stage fruits than in the semi-red-stage fruits. Subcellular localization indicated that the <i>ZjFLS</i> gene was located in the nucleus, cytoplasmic matrix, and cytoplasmic membrane. …”
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Amyloidogenic immunoglobulin light chains disturb contractile function and calcium transients in a human cardiac spheroid model of light chain (AL) amyloidosis by Mélanie Bézard, Jean-Sébastien Vartanian-Grimaldi, Julien Henri, Denisa Calin, Amira Zaroui, Mounira Kharoubi, Thibaud Damy, Onnik Agbulut, Ekaterini Kordeli

“…In this work, we have set up a human cellular disease model of AL cardiac amyloidosis (AL-CA) in the form of cardiac spheroids, to study the cytotoxic effects of amyloidogenic LCs with regard to contractile function and calcium handling. To mimic the disease in a reconstituted system, soluble amyloidogenic LCs purified from urine of AL-CA patients were added to a mixture of induced pluripotent stem cell-issued human cardiomyocytes (hiPSC-CM) and human primary cardiac fibroblasts, which resulted in formation of spheroids within 7 days. …”
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Home settings are associated with less functional decline among older adults compared to community-care foster homes and skilled nursing facilities in Hawaii. by Hua Zan, Yanyan Wu, Yan Luo, John P Barile, Joshua R Holmes, Joy Agner

“…To increase comparability despite these differences, we matched older adults (n = 852) on baseline functional status, age, sex, marital status, and race/ethnicity using propensity score matching and performed sensitivity analyses on cognitive status. …”
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