Revolutionizing nerve regeneration: A novel approach using polylactic acid/chitosan conduit with nerve-like cells and Bacopa monnieri in male rat model by Elham Hoveizi, Hadi Naddaf, Emad Naeimavi

“…Objectives: This research aims to use neural-like cells (NLCs) derived from endometrial mesenchymal stem cells (EnMSCs) on a polylactic acid/chitosan scaffold (PLA/CS) along with the use of bacopa monnieri (Memocopa) in a rat sciatic nerve injury model for sciatic nerve regeneration. …”
Get full text

Identification of Cancer Stem Cell (CSC)-Associated Genes, Prognostic Value, and Candidate Drugs as Modulators of CSC-Associated Signaling in Carcinomas Through a Multiomics Data A... by Pallabi Mondal, Poulami Singh, Krishna Mahanti, Sankar Bhattacharyya

“…Background: Cancer stem cells (CSCs) are a small subpopulation of cancer cells that have the potential for self-renewal and a strong proliferative capacity, and sustain tumorigenesis capabilities. …”
Get full text

Regression analysis and artificial neural networks for predicting pine species volume in community forests by Wenceslao Santiago-García

“…This proposed ANN model represents a significant advancement in modeling both whole-tree and stem volume simultaneously and independently across different species, providing reliable and precise estimates. …”
Get full text

Reduced microstructural white matter integrity is associated with the severity of physical symptoms in functional neurological disorder by Nicolas Gninenko, Eliane Müller, Selma Aybek

“…Background: Functional neurological disorder (FND) is linked to functional changes in brain networks without an underlying brain lesion. …”
Get full text

Species-Specific Enhancer Activity of OCT4 in Porcine Pluripotency: The Porcine OCT4 Reporter System Could Monitor Pluripotency in Porcine Embryo Development and Embryonic Stem Cel... by Seung-Hun Kim, Mingyun Lee, Kwang-Hwan Choi, Jinsol Jeong, Dong-Kyung Lee, Jong-Nam Oh, Gyung Cheol Choe, Chang-Kyu Lee

“…The present study examined the activity and function of the pig OCT4 enhancer in the porcine early embryonic development stage and porcine authentic embryonic stem cells. …”
Get full text

Improving the therapeutic profile of MSCs: Cytokine priming reduces donor-dependent heterogeneity and enhances their immunomodulatory capacity by Jaris Valencia, Jaris Valencia, Jaris Valencia, Rosa M. Yáñez, Rosa M. Yáñez, Rosa M. Yáñez, Sandra Muntión, Sandra Muntión, Sandra Muntión, María Fernández-García, María Fernández-García, María Fernández-García, Jorge Diego Martín-Rufino, Jorge Diego Martín-Rufino, Agustín G. Zapata, Agustín G. Zapata, Agustín G. Zapata, Juan A. Bueren, Juan A. Bueren, Juan A. Bueren, Ángeles Vicente, Ángeles Vicente, Ángeles Vicente, Fermín Sánchez-Guijo, Fermín Sánchez-Guijo, Fermín Sánchez-Guijo

Get full text

Patient Experience and Wound Healing Outcomes Using Different Palatal Protection Methods After Free Gingival Grafts: A Systematic Review by Tomasz Jankowski, Agnieszka Jankowska, Mirona Palczewska-Komsa, Maciej Jedliński, Wojciech Kazimierczak, Joanna Janiszewska-Olszowska

Get full text

Polyethylene glycol-phospholipid functionalized single-walled carbon nanotubes for enhanced siRNA systemic delivery by Yuen-Fen Tan, Ling-Wei Hii, Wei-Meng Lim, Soon-Keng Cheong, Chee-Onn Leong, Maxine Swee-Li Yee, Chun-Wai Mai

Get full text

Utilizing Forest Trees for Mitigation of Low-Frequency Ground Vibration Induced by Railway Operation by Zeyu Zhang, Xiaohui Zhang, Zhiyao Tian, Chao He

“…This study proposes a three-dimensional semi-analytical method developed for evaluating the dynamic responses of the coupled track–ground–tree system. …”
Get full text

Importance of E/e’ and BNP for early detection of late cardiotoxicity in long-term follow-up of childhood hematologic cancer survivors: a retrospective cross-sectional study by Yuri Okazoe-Hirakawa, Kimikazu Yakushijin, Keiji Kurata, Sakuya Matsumoto, Hiroya Ichikawa, Rina Sakai, Taku Nose, Shiro Kimbara, Yoshiaki Nagatani, Taiji Koyama, Yumiko Inui, Yohei Funakoshi, Naomi Kiyota, Mitsuhiro Ito, Keiko Hatazawa, Hidekazu Tanaka, Nobuyuki Yamamoto, Hironobu Minami

“…The E/e’ ratio was significantly higher in survivors with a history of hematopoietic stem cell transplantation (HSCT) than in those who did not undergo HSCT (median, 8.4% vs. 6.25%, P = 0.040), while no intergroup differences were observed in ejection fraction (EF), global longitudinal strain (GLS), or the brain natriuretic protein (BNP) level. …”
Get full text

FOXL2 drives the differentiation of supporting gonadal cells in early ovarian development by Laura Danti, Karolina Lundin, Petra Nedeczey-Ruzsák, Timo Tuuri, Juha S. Tapanainen

Get full text

Predicting hepatocellular carcinoma outcomes and immune therapy response with ATP-dependent chromatin remodeling-related genes, highlighting MORF4L1 as a promising target by Chao Xu, Litao Liang, Guoqing Liu, Yanzhi Feng, Bin Xu, Deming Zhu, Wenbo Jia, Jinyi Wang, Wenhu Zhao, Xiangyu Ling, Yongping Zhou, Wenzhou Ding, Lianbao Kong

“…Experimentally, MORF4L1 was demonstrated to enhance cancer stemness by activating the Hedgehog signaling pathway, as supported by both in vitro and in vivo assays. …”
Get full text

Prevalence of Depressive Symptoms in Patients Undergoing Aseptic Revision Total Hip Arthroplasty Differs Based on Mode of Failure by Kristen I. Barton, MD, PhD, Daniel N. Bracey, MD, PhD, Vishal Hegde, MD, Aviva Pollet, MS, Roseann Johnson, BSc, Douglas A. Dennis, MD, Jason M. Jennings, MD, DPT

“…Patients with depressive symptoms had significantly lower physical component score with instability, aseptic loosening, stem pain, and metallosis preoperatively (P < .001) and with instability, aseptic loosening, stem pain, and polyethylene wear postoperatively (P = .002). …”
Get full text

Long-term outcomes of mesenchymal stem cell therapy in severe COVID-19 patients: 3-year follow-up of a randomized, double-blind, placebo-controlled trial by Meng-Qi Yuan, Le Song, Ze-Rui Wang, Zi-Ying Zhang, Ming Shi, Junli He, Qiong Mo, Ning Zheng, Wei-Qi Yao, Yu Zhang, Tengyun Dong, Yuanyuan Li, Chao Zhang, Jinwen Song, Lei Huang, Zhe Xu, Xin Yuan, Jun-Liang Fu, Cheng Zhen, Jianming Cai, Jinghui Dong, Jianzeng Zhang, Wei-Fen Xie, Yonggang Li, Bo Zhang, Lei Shi, Fu-Sheng Wang

“…The general health (GH) score from the SF-36 was higher in the MSC group (67.0) compared to the placebo group (50.0), with a difference of 12.86 (95% CI: 1.44–24.28). Both groups showed similar results for total lung severity scores (TSS), 6-MWD, pulmonary function tests, and Long COVID symptoms. …”
Get full text

Exploring the functional quality attributes of smart home for older adults based on qualitative research and Kano model by Qin Yang, Qin Yang, Peishan Li, Xing Liu, Chunnan Wei

“…BackgroundThis study investigates the functional attributes of smart home for older adults across different age groups, aiming to identify features that fulfill users’ needs and give convenience, thereby offering scientific guidance for future smart home designs for older adults.MethodsEmploying a multi-stage approach, this study commences with semi-structured interviews with older participants in China, analyzing transcripts using NVivo to guide questionnaire design. …”
Get full text

Retention and Functional Effect of Adipose-Derived Stromal Cells Administered in Alginate Hydrogel in a Rat Model of Acute Myocardial Infarction by Bjarke Follin, Adam Ali Ghotbi, Andreas Ettrup Clemmensen, Simon Bentsen, Morten Juhl, Rebekka Harary Søndergaard, Lisbeth Drozd Lund, Mandana Haack-Sørensen, Philip Hasbak, Smadar Cohen, Rasmus Sejersten Ripa, Jens Kastrup, Annette Ekblond, Andreas Kjær

Get full text

Intellectual, Mnemonic, and Frontal Functions in Dementia with Lewy Bodies: A Comparison with Early and Advanced Parkinson’s Disease by John Joseph Downes, Nicholas M. Priestley, Mark Doran, Jose Ferran, Eric Ghadiali, Paul Cooper

Get full text

Bias Correction of Terrestrial Water Availability: Comparison of Trend‐Preserving Cumulative Distribution Function Matching Methods by Jingyi Li, Boqiang Qin

“…This study introduces the grid‐by‐grid cumulative distribution function (CDF) matching method to correct simulation bias in P−E, based on the ERA5‐Land dataset and outputs from 13 selected CMIP6 global climate models. …”
Get full text

Thermoelastic Analysis of a Functionally Graded Simple Blade Using First-Order Shear Deformation Theory by Manouchehr Mohammad Hosseini Mirzaei, Mohammad Arefi, Abbas Loghman

“…In this article, the thermo-elastic behavior of a functionally graded simple blade subjected to the mechanical and thermal loadings is presented, applying a semi-analytical method and a variable thickness cantilever beam model. …”
Get full text

α-Pinene, Limonene, and Cyclohexene Secondary Organic Aerosol Hygroscopicity and Oxidation Level as a Function of Volatility by Kerrigan P. Cain, Aikaterini Liangou, Michael L. Davidson, Spyros N. Pandis

“…Use of this technique with different OA systems, both laboratory and ambient, can supply parameters that can be incorporated in atmospheric chemical transport models.…”
Get full text