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High NK cell counts at day 90 predict improved survival in event-free patients after T-cell depleted allogeneic stem cell transplantation
Published 2025-06-01“…However, data on the impact of different lymphocyte subsets influencing outcomes is conflicting. …”
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542
Effect of <i>CTLA4</i> gene polymorphism on relapse probability among patients with acute leukemias after allogenic hematopoietic stem cells transplantation
Published 2019-04-01“…Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is being widely applied as a therapy for hematological malignancies. …”
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543
PSMB10 maintains the stemness of chemotherapeutic drug-resistant leukemia cells by inhibiting senescence and cytotoxic T lymphocyte-mediated killing in a ubiquitinated degradation...
Published 2025-06-01“…The genetic inactivation of PSMB10 resulted in increased senescence and cytotoxic T lymphocyte (CTL) killing, as well as increased intracellular drug concentrations and drug-induced cellular senescence in different types of human AML cells, which also impeded human and murine leukemia initiation and stemness maintenance in vivo with a 19-fold decrease in the frequency of human LSCs and a 7.6-fold decrease of drug-resistant mouse LSCs, while normal hematopoietic cells remained unaffected. …”
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544
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546
Histological Alterations and Interferon-Gamma and AKT-mTOR Expression in an Experimental Model of Achilles Tendinopathy—A Comparison of Stem Cell and Amniotic Membrane Treatment
Published 2025-02-01“…The search for new therapeutic tools, using cell therapies with stem cells (SC) and biological tissues, such as amniotic membranes (AM), has proved useful for the regeneration of injured tendons. …”
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547
Analysis of Clade V MLO Gene Expressions in Hazelnut Leaves upon Exposure to Powdery Mildew
Published 2022-04-01Get full text
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548
Seasonal and Species‐Level Water‐Use Strategies and Groundwater Dependence in Dryland Riparian Woodlands During Extreme Drought
Published 2024-04-01“…Our results suggest that both species functioned as facultative phreatophytes that used shallow soil moisture when available but ultimately relied on groundwater to maintain physiological function during drought. …”
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549
Protective Effects of Different Shapes of Ecological Rip-rap Bags Based on CFD-DPM Model
Published 2025-04-01“…In conclusion, rectangular rip-raping bags offers better protection for the adjacent concave bank, while semi-cylindrical bags provide the most effective sand-blocking function.…”
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550
The Comparison of Two Functional Movements in Knee Joint Proprioception Assessment of Healthy Female Athletes
Published 2009-06-01“…Knee joint position sense was evaluated by the reproduction of the target angle in weight-bearing position and two different tasks of movement (from full extension to 30° flexion and from semi squat (60° flexion) to 30° flexion). …”
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551
Computational analysis of spliced leader trans-splicing in the regenerative flatworm <i>Macrostomum lignano</i> reveals its prevalence in conserved and stem cell related genes
Published 2021-03-01“…However, only a fraction of trans-spliced genes reside in operons, suggesting that SL trans-splicing must also have some other, less understood functions. Regenerative flatworms are informative model organisms which hold the keys to understand the mechanism of stem cell regulation and specialization during regeneration and homeostasis. …”
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552
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553
Characterization and Functional Analysis of 4-Coumarate:CoA Ligase Genes in Mul-berry.
Published 2016-01-01Get full text
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554
Respective association of joint space narrowing and osteophyte formation with knee symptoms and function in China
Published 2025-04-01“…Conclusion This study found that JSN and osteophytes had different impacts on function and symptoms in KOA. …”
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555
Delivery of A Chemically Modified Noncoding RNA Domain Improves Dystrophic Myotube Function
Published 2025-05-01“…Here, we identify an independent functional element within human CYTOR, and optimize its RNA delivery. …”
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556
Optimization of Multi-Source Remote Sensing Soil Salinity Estimation Based on Different Salinization Degrees
Published 2025-04-01“…Specifically, this study integrated in situ hyperspectral data and satellite multispectral data using spectral response functions. Subsequently, machine learning methods such as random forest (RF), extreme gradient boosting (XGBoost), support vector machine (SVM), and multiple linear regression (MLR) were employed, in combination with sensitive spectral indices, to develop a multi-source remote sensing soil salinity estimation model optimized for different salinization degrees (mild or lower salinization vs. moderate or higher salinization). …”
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557
Umbilical Cord-Derived Mesenchymal Stem Cells Attenuate S100-Induced Autoimmune Hepatitis via Modulating Th1 and Th17 Cell Responses in Mice
Published 2023-01-01“…Previous studies reported on the applicability and safety of mesenchymal stem cells (MSCs) to ameliorate liver inflammation and fibrosis. …”
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558
ABCB1 confers resistance to carboplatin by accumulating stem-like cells in the G2/M phase of the cell cycle in p53null ovarian cancer
Published 2025-04-01“…This suggests that high levels of stemness and attenuated DNA repair function exhibited in the G2/M-accumulated portion may be a key contributor of chemoresistance in patients with ovarian cancer bearing a p53null mutation, but not other types of mutations expressing p53. …”
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559
Human spindle-shaped urine-derived stem cell exosomes alleviate severe fatty liver ischemia–reperfusion injury by inhibiting ferroptosis via GPX4
Published 2025-02-01“…Abstract Background Severe hepatic steatosis can exacerbate Ischemia–reperfusion injury (IRI), potentially leading to early graft dysfunction and primary non-function. In this study, we investigated the heterogeneity of different subpopulations of Urine-derived stem cells (USCs) to explore the most suitable cell subtype for treating severe steatotic liver IRI. …”
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560
Effects of Human Mesenchymal Stem Cells Isolated from Wharton’s Jelly of the Umbilical Cord and Conditioned Media on Skeletal Muscle Regeneration Using a Myectomy Model
Published 2014-01-01“…The in vivo application of human mesenchymal stem cells (HMSCs) of the umbilical cord and the conditioned media (CM) where the HMSCs were cultured and expanded, associated with different vehicles to induce muscle regeneration, was evaluated in a rat myectomy model. …”
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