PPARs Expression in Adult Mouse Neural Stem Cells: Modulation of PPARs during Astroglial Differentiaton of NSC by A. Cimini, L. Cristiano, E. Benedetti, B. D'Angelo, M. P. Cerù

“…PPAR isotypes are involved in the regulation of cell proliferation, death, and differentiation, with different roles and mechanisms depending on the specific isotype and ligand and on the differentiated, undifferentiated, or transformed status of the cell. …”
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Preconditioning and Engineering Strategies for Improving the Efficacy of Mesenchymal Stem Cell-Derived Exosomes in Cell-Free Therapy by Shenyuan Chen, Fengtian Sun, Hui Qian, Wenrong Xu, Jiajia Jiang

“…Mesenchymal stem cells (MSCs) have been widely applied to regenerative medicine owing to their multiple differentiation, self-renewal, and immunomodulatory abilities. …”
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Extreme restructuring of cis-regulatory regions controlling a deeply conserved plant stem cell regulator. by Danielle Ciren, Sophia Zebell, Zachary B Lippman

“…Here, we investigated these questions using a plant stem cell regulator conserved in expression pattern and function over ~125 million years. …”
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Sex differences in personality dysfunction in help-seeking adolescents by Marialuisa Cavelti, Jana Schenk, Silvano Sele, Corinna Reichl, Julian Koenig, Ines Mürner-Lavanchy, Michael Kaess

“…Personality dysfunction was assessed using the Semi-Structured Interview for Personality Functioning DSM-5 (STiP 5.1). …”
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Light Exposure as a Tool to Enhance the Regenerative Potential of Adipose-Derived Mesenchymal Stem/Stromal Cells by Kaarthik Sridharan, Tawakalitu Okikiola Waheed, Susanne Staehlke, Alexander Riess, Mario Mand, Juliane Meyer, Hermann Seitz, Kirsten Peters, Olga Hahn

“…Photobiomodulation (PBM) utilizes different wavelengths of light to modulate cellular functions and has emerged as a promising approach in regenerative medicine. …”
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Mesenchymal stem cell application in pulmonary disease treatment with emphasis on their interaction with lung-resident immune cells by Ali Hazrati, Seyed Mohamad Javad Mirarefin, Kosar Malekpour, Arezou Rahimi, Arezou Khosrojerdi, Ashkan Rasouli, Susan Akrami, Sara Soudi

“…Furthermore, they can secrete exosomes that affect the function of lung cells and immune cells and change their function. …”
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Targeting cellular senescence in kidney diseases and aging: A focus on mesenchymal stem cells and their paracrine factors by Seyyedeh Mina Hejazian, Seyyed Sina Hejazian, Seyyedeh Mina Mostafavi, Seyed Mahdi Hosseiniyan, Soheila Montazersaheb, Mohammadreza Ardalan, Sepideh Zununi Vahed, Abolfazl Barzegari

“…The presence of accumulated senescent cells, whether transiently (acute senescence) or persistently (chronic senescence) plays a dual role in various conditions such as natural kidney aging and different kidney disorders. Elevations in senescent cells and senescence-associated secretory phenotype (SASP) levels correlate with decreased kidney function, kidney ailments, and age-related conditions. …”
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DNA Methylation Changes during In Vitro Propagation of Human Mesenchymal Stem Cells: Implications for Their Genomic Stability? by Angela Bentivegna, Mariarosaria Miloso, Gabriele Riva, Dana Foudah, Valentina Butta, Leda Dalprà, Giovanni Tredici

“…Mesenchymal stem cells (MSCs) hold great promise for the treatment of numerous diseases. …”
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Heterogeneous protein dynamics links to mitochondrial activity, glucose transporter, and ALDH cancer stem cell properties by Martin Krkoška, Zuzana Tylichová, Pavlína Zatloukalová, Petr Müller, Bořivoj Vojtěšek, Philip John Coates

“…Abstract Background Cancer stem-like cells (CSCs) represent a subset of tumor cells that have the ability to self-renew, a long lifespan and a relatively quiescent phenotype, and show resistance to conventional therapies. …”
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Retinoic and ascorbic acids induce osteoblast differentiation from human dental pulp mesenchymal stem cells by Lina M. Escobar, José Daniel Escobar, Zita Bendahan, Jaime E. Castellanos

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The effects of Klotho delivering mesenchymal stem cell-derived small extracellular vesicles on acute kidney injury by Xiao-Hui Deng, Zi-Cong Wu, Qi Sun, Long-Xin Huang, Ying-Chun Xie, Dong-Xiao Lou, Chan-Gu Li, Xiao-Qing Liu, Zhi-Rou Zhou, Tian Tian, Chang-Lin Lian, Qing-Ling Fu

“…Abstract Acute kidney injury (AKI) is a life-threating syndrome characterized by sudden loss of kidney function, and its management is challenging and often suboptimal. …”
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Autoimmunity and clinical pathology amelioration in SLE by dexamethasone primed mesenchymal stem cell derived conditioned media by Khushbu Priya, Sonali Rawat, Doli Das, Manaswi Chaubey, Hiral Thacker, Kiran Giri, Shambhavi Singh, Madhukar Rai, Sujata Mohanty, Geeta Rai

“…Abstract Background This study aimed to investigate the therapeutic potential of cell-free Dexamethasone (Dex) primed Wharton’s jelly Mesenchymal stem cells derived conditioned media (DW) in addressing complications associated with systemic lupus erythematosus (SLE), focusing on its immunomodulatory effects. …”
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Bone Marrow Mesenchymal Stem Cell-Derived Exosomes Modulate Chemoradiotherapy Response in Cervical Cancer Spheroids by Kesara Nittayaboon, Piyatida Molika, Rassanee Bissanum, Kittinun Leetanaporn, Nipha Chumsuwan, Raphatphorn Navakanitworakul

“…<b>Background:</b> Bone marrow mesenchymal stem cells (BM-MSCs) are significant in chemo- and radiotherapy resistance. …”
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Adipocyte-Mediated Electrophysiological Remodeling of PKP-2 Mutant Human Pluripotent Stem Cell-Derived Cardiomyocytes by Justin Morrissette-McAlmon, Christianne J. Chua, Alexander Arking, Stanley Chun Ming Wu, Roald Teuben, Elaine Zhelan Chen, Leslie Tung, Kenneth R. Boheler

“…Conclusions: Our study shows that hiPSC-CMs from normal and mPKP2 ACM lines exhibit distinct molecular and functional responses to paracrine factors, with differences in RNA expression and electrophysiology. …”
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Insulin-Sensitizing Properties of Decoctions from Leaves, Stems, and Roots of <i>Cucumis prophetarum</i> L. by Zewdie Mekonnen, Giuseppe Petito, Getasew Shitaye, Gianluca D’Abrosca, Belete Adefris Legesse, Sisay Addisu, Maurizio Ragni, Antonia Lanni, Roberto Fattorusso, Carla Isernia, Lara Comune, Simona Piccolella, Severina Pacifico, Rosalba Senese, Gaetano Malgieri, Solomon Tebeje Gizaw

“…Type 2 diabetes mellitus (T2DM) is a chronic disease characterized by insulin resistance and impaired beta-cell secretory function. Since existing treatments often present side effects based on different mechanisms, alternative therapeutic options are needed. …”
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Soil moisture sensor for agricultural applications inspired from state of art study of surfaces scattering models &amp; semi-empirical soil moisture models by Amit Kumar Shakya, Ayushman Ramola, Akhilesh Kandwal, Anurag Vidyarthi

“…In this research work, models for the scattering from rough surfaces and semi-empirical soil moisture models are presented. …”
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Modeling SMAD2 Mutations in Induced Pluripotent Stem Cells Provides Insights Into Cardiovascular Disease Pathogenesis by Tarsha Ward, Sarah U. Morton, Gabriela Venturini, Warren Tai, Min Young Jang, Joshua Gorham, Dan Delaughter, Lauren K. Wasson, Zahra Khazal, Jason Homsy, Bruce D. Gelb, Wendy K. Chung, Benoit G. Bruneau, Martina Brueckner, Martin Tristani‐Firouzi, Steven R. DePalma, Christine Seidman, J. G. Seidman

“…We constructed isogenic induced pluripotent stem cells with heterozygous or homozygous loss‐of‐function and missense SMAD2 variants identified in CHD probands. …”
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Identification of biomarkers associated with proliferation and differentiation of mesenchymal stem cells in pulmonary adenocarcinoma and establishment of prognostic models by Xin-Xin Zeng, Ke-Xin Xian, Jie-Lun Wen, Qi-Zhe Wang, Xin-Yu Wang, Li-Yue Sun

“…Abstract Background Mesenchymal stem cells (MSCs) hold potential as therapeutic agents in cancer, but their mechanisms in lung adenocarcinoma (LUAD) remain poorly understood. …”
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Role of bone marrow-derived mesenchymal stem cells on the parotid glands of streptozotocin induced diabetes rats by Mona Denewar, Laila E. Amin

“…Immunohistochemical examination of aquaporin-5 showed significant difference between the two groups. Conclusion: bone marrow derived stem cell treatment considers as an improved methods in prevention and treatment of diabeticinduced hyposalivation.…”
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Meta-Analysis of the Therapeutic Effects of Stem Cell-Derived Extracellular Vesicles in Rodent Models of Hemorrhagic Stroke by Conglin Wang, Bo Yan, Pan Liao, Fanglian Chen, Ping Lei

“…Background. Stem cell-derived extracellular vesicles (SCEVs) have emerged as a potential therapy for hemorrhagic stroke. …”
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