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201
Autologous Bone Marrow Stem Cells in the Treatment of Chronic Liver Disease
Published 2012-01-01“…We also outline the different mechanisms by which stem cells may impact on liver disease.…”
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202
Stem Cell Modeling of Core Binding Factor Acute Myeloid Leukemia
Published 2016-01-01“…Even though clonally originated from a single cell, acute leukemia loses its homogeneity soon and presents at clinical diagnosis as a hierarchy of cells endowed with different functions, of which only a minority possesses the ability to recapitulate the disease. …”
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203
Mesenchymal Stem Cell Therapy for Huntington Disease: A Meta-Analysis
Published 2023-01-01“…MSCs transplanted before the occurrence of motor dysfunction rescued the motor incoordination of HD. Among different MSC sources, bone marrow mesenchymal stem cells were the most investigated cells and were effective in improving motor coordination. …”
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204
Alternative splicing in stem cells and development: research progress and emerging technologies
Published 2025-06-01“…Overall, this field is rapidly evolving, revealing new insights into how alternative splicing shapes the molecular landscape and functions of stem cells and developmental processes.…”
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205
Human Pluripotent Stem Cell Culture: Current Status, Challenges, and Advancement
Published 2018-01-01“…In this review, we discuss different media, their components and functions, including specific requirements to maintain the pluripotent and proliferative ability of hPSCs. …”
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206
Tumor-associated mesenchymal stem/stromal cells in tumor microenvironment and carcinogenesis
Published 2025-07-01“…Abstract Mesenchymal stem/stromal cells (MSCs) possess significant potential in regenerative medicine, attributed to their inherent capacity for site-specific homing to inflammatory regions, diverse differentiation abilities, and immunomodulatory functions. …”
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207
Electrical Stimulation Promotes Stem Cell Neural Differentiation in Tissue Engineering
Published 2021-01-01“…Nerve injuries and neurodegenerative disorders remain serious challenges, owing to the poor treatment outcomes of in situ neural stem cell regeneration. The most promising treatment for such injuries and disorders is stem cell-based therapies, but there remain obstacles in controlling the differentiation of stem cells into fully functional neuronal cells. …”
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208
Bridging the Gap: ChatGPT’s Role in Enhancing STEM Education
Published 2025-04-01“…The theme of feedback is different between two conditions. That is, human feedback emphasizes scientific and detailed approaches while ChatGPT feedback emphasizes educational aspects and cognitive functions. …”
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209
Differential exosome miRNA expression in oral cancer stem cells
Published 2020-03-01“…The primary objective of this study was to explore potential differences in miRNA content between OSCC and OSCC stem cells. …”
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210
Nitrogen and water additions with or without mowing altered soil microbial community characteristics in a semi-arid steppe
Published 2025-01-01“…Conclusions Overall, N, water addition, and clipping individually and/or interactively, in distinct degrees, altered soil microbial interaction, community structure, and the potential function in a semi-arid steppe. These findings enhance our understanding of soil microbial community assembly and provide a scientific basis for managing temperate grasslands, particularly in the context of global change's impact on ecosystem function and stability.…”
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Expansion of human megakaryocyte-biased hematopoietic stem cells by biomimetic Microniche
Published 2023-04-01“…Abstract Limited numbers of available hematopoietic stem cells (HSCs) limit the widespread use of HSC-based therapies. …”
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213
Stemness-driven clusters in ovarian cancer: immune characteristics and prognostic implications
Published 2025-06-01“…Single-cell RNA sequencing was used to investigate stemness-related cell types. Functional assays were conducted to validate the role of AKAP12 in OC progression.ResultsThree distinct stemness-related subgroups were identified with significant differences in prognosis and immunological features. …”
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214
Lactobacillus delbrueckii subsp. bulgaricus 2038 and Streptococcus thermophilus 1131 ameliorate barrier dysfunction in human induced pluripotent stem cell-derived crypt-villus stru...
Published 2025-06-01“…However, Caco-2 cells differ from living organisms in various ways. We have developed a human induced pluripotent stem cell-derived crypt-villus structural small intestine (hiPSC-SI) was established with a villus-like structure containing constituent cells of the small intestine.MethodsA hiPSC-SI and LAB co-culture model was established to assess the impact of LAB on barrier function and elucidate the underlying mechanisms.ResultsThe medium on the luminal side for co-culturing cells and bacteria was examined and determined to use Hanks’ balanced salt solution without glucose in terms of bacterial survival rate. …”
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215
Deciphering crop-specific rhizobacteriome assembly in cotton, sorghum, and soybean under hot semi-arid field conditions in Texas
Published 2025-08-01“…By exploring rhizobacterial recruitment strategies and differential microbial associations in these crops, this study addresses critical gaps in plant-microbiome interactions and paves the way for practical applications in hot semi-arid agricultural systems. Results We found that the abundances and structures of rhizospheric bacterial communities differed among sorghum, soybean, and cotton, with the differences being closely linked to their predicted functional roles in stress adaptation and nutrient assimilation. …”
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216
Evaluation of semi prepared probiotic dessert containing phycoerythrin and Lactobacillus plantarum for period of up to two months within the refrigerator
Published 2025-07-01“…Abstract The isolation of functional bioactive compounds from microalgae as sustainable sources has emerged as a new area of focus in pharmacology and functional food research. …”
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217
A Semi-Mechanistic Mathematical Model of Immune Tolerance Induction to Support Preclinical Studies of Human Monoclonal Antibodies in Rats
Published 2025-06-01“…Model-derived erenumab concentration–time profiles served as input for a quantitative system pharmacology-style semi-mechanistic model of the adaptive immune system to conceptualize the ADA response as a function of the kinetics of CD4<sup>+</sup> T helper cells and T regulatory cells. …”
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Assessing the Efficiency and Role of Eivan Based on Users’ Perception: A Semi-open Space in Rural Vernacular Houses of Mazandaran
Published 2018-06-01“…Given that the lifestyle is enmeshed with the nature and because of the special characteristics of the environment of this region, semi-open spaces generally, and loggia particularly, play various functional, aesthetical, climatic, cultural, and social roles within vernacular houses. …”
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Combatting environmental impacts and microbiological pollution risks in Potato cropping: Benefits of forage cultivation in a semi-arid region
Published 2025-06-01“…Continuous potato cropping in semi-arid regions, which are vulnerable to erosion, reduces tuber yields and leads to a decline in soil quality. …”
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