A pan-cancer analysis of the oncogenic and immunological roles of RGS5 in clear cell renal cell carcinomas based on in vitro experiment validation by Ying Zhang, Huming Wang, Fang Dai, Ke He, Zhouting Tuo, Jinyou Wang, Liangkuan Bi, Xin Chen

“…Additionally, RGS5 expression is closely linked to tumor heterogeneity and stemness indicators across different cancer types. …”
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In silico model of mechano-biochemical bone remodeling characterizes the therapeutic effects of osteoporosis drugs depending on the action mechanism by Yoshitaka Kameo, Kei Imai, Yuki Miya, Young Kwan Kim, Taiji Adachi

“…Osteoporosis stems from an imbalance between bone resorption and formation during bone remodeling, a mechano-biochemical coupling event that intercellular signaling regulates among the bone cells in response to the mechanical environment. …”
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Combining metabolomics and transcriptomics to reveal the effect of β-glucosidase on scopolin in Angelica dahurica var. formosana by Yalan Wang, Han Hu, Zhihui Zhou, Duanyang Li, Feixia Hou, Cheng Peng, Jinhui Bian, Jihai Gao

“…Therefore, we selected BGLU genes from ADF to investigate their biological functions. Here, we performed transcriptomic and untargeted metabolomic analyses to explore the metabolic characteristics of different tissues and their associated gene regulation. …”
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Exploring the threshold of human activity impact on urban ecosystem service value: a case study of Hefei, China by Zhiqiang Yao, Shi Chen, Yinlan Huang

“…This study fills a significant gap in our understanding of the threshold effects of HAI on different functional components of ESV and the identification of local anomalous information. …”
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The unity of Newton’s worldview: anthropological aspect by Ivan Regulskiy

“…However, his legacy was perceived in a different light; for example, J.-B. Biot believed that Newton's occupation with theology was the result of a decline in his mental powers. …”
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Planning a Clinical Development Programme for Medicinal Products for Irritable Bowel Syndrome: An Analysis of the European Medicines Agency’s Recommendations by E. A. Gerasimets, N. A. Rumyantsev, R. S. Ilin, D. V. Goryachev

“…Irritable bowel syndrome (IBS) is a chronic functional disorder present in over 13% of the population. …”
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Gene Expression Analysis of Deduced Protein Sequence from the FLOWERING LOCUS C (FLC) Homolog during Vegetative and Reproductive Phases in Lepidium sativum L. by Parissa Jonoubi, Farkhondeh Rezanejad, Fatemeh Mahyapoor

“…Results showed that LsFLC expression levels were very high in the root and relatively high in leaves and stems, whereas no expression was allowed in flowers. …”
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Magnetic nanoparticle detection methods in the context of complex fluids by Alirza Orujov, Jon M. Pikal, TeYu Chien, Jefferson A. Carter, Saman A. Aryana

“…The feasibility of using these nanoparticles for monitoring purposes stems from their detectability at low concentrations in subsurface environments. …”
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The quality of the organic materials determines its carbon conversion efficiency in tropical latosol by Shuhui Song, Siru Liu, Yanan Liu, Lei Shi, Huayong Li, Weiqi Shi, Haiyang Ma

“…CCH mainly enhanced soil phenol oxidase activity and maintained microbial biomass stabilityin the long-term (1080 days).DiscussionThis study revealed the changes of microbial diversity and enzyme activity under different organic materials. The promotion effects of PAL and BAS on microbial biomass, diversity and enzyme activity in the short term and the maintenance effects of CCH on the stability of microbial biomass in the later period were investigated, which provided a new basis for further exploring the function and mechanism of microorganisms in soil ecosystems.…”
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The Mutations in <i>RcMYB114</i> Affect Anthocyanin Glycoside Accumulation in Rose by Maofu Li, Yuan Yang, Hua Wang, Pei Sun, Shuting Zhou, Yanhui Kang, Xiangyi Sun, Min Jin, Wanmei Jin

“…The two non-synonymous mutations of <i>RcMYB114</i> do not affect the function of the gene itself, but the content of the anthocyanins accumulated was different. …”
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Clerodendrum trichotomum Thunb.: a review on phytochemical composition and pharmacological activities by Linzhen Li, Linzhen Li, Linzhen Li, Zhiyi Tang, Zhiyi Tang, Shengjia Xiao, Shengjia Xiao, Xiangjie Dai, Xiangjie Dai, Yutong Wang, Yutong Wang, Xi Wei

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Identification of MRS2 Gene Family and Expression Analysis in Response to Magnesium Treatment in <i>Malus domestica</i> by Jiying Bao, Huimin Gou, Shangwen Yang, Guoping Liang, Juan Mao

“…Tissue-specific expression profiles revealed the differential expression patterns of <i>MdMRS2</i> members in different tissues such as the apple roots, stems, leaves, seedlings, seeds, flowers, and fruits. …”
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Effect of climate on traits of dominant and rare tree species in the world’s forests by Iris Hordijk, Lourens Poorter, Jingjing Liang, Peter B. Reich, Sergio de-Miguel, Gert-Jan Nabuurs, Javier G. P. Gamarra, Han Y. H. Chen, Mo Zhou, Susan K. Wiser, Hans Pretzsch, Alain Paquette, Nicolas Picard, Bruno Hérault, Jean-Francois Bastin, Giorgio Alberti, Meinrad Abegg, Yves C. Adou Yao, Angelica M. Almeyda Zambrano, Braulio V. Alvarado, Esteban Alvarez-Davila, Patricia Alvarez-Loayza, Luciana F. Alves, Iêda Amaral, Christian Ammer, Clara Antón-Fernández, Alejandro Araujo-Murakami, Luzmila Arroyo, Valerio Avitabile, Gerardo A. Aymard C, Timothy Baker, Olaf Banki, Jorcely Barroso, Meredith L. Bastian, Luca Birigazzi, Philippe Birnbaum, Robert Bitariho, Pascal Boeckx, Frans Bongers, Olivier Bouriaud, Pedro H. S. Brancalion, Susanne Brandl, Francis Q. Brearley, Roel Brienen, Eben N. Broadbent, Helge Bruelheide, Roberto Cazzolla Gatti, Ricardo G. Cesar, Goran Cesljar, Robin L. Chazdon, Chelsea Chisholm, Emil Cienciala, Connie J. Clark, David B. Clark, Gabriel Colletta, David Coomes, Fernando Cornejo Valverde, Jose J. Corral-Rivas, Philip Crim, Jonathan Cumming, Selvadurai Dayanandan, André L. de Gasper, Mathieu Decuyper, Géraldine Derroire, Ben DeVries, Ilija Djordjevic, Aurélie Dourdain, Jiri Dolezal, Nestor Laurier Engone Obiang, Brian Enquist, Teresa Eyre, Adandé Belarmain Fandohan, Tom M. Fayle, Leandro V. Ferreira, Ted R. Feldpausch, Leena Finér, Markus Fischer, Christine Fletcher, Lorenzo Frizzera, Damiano Gianelle, Henry B. Glick, David Harris, Andrew Hector, Andreas Hemp, John Herbohn, Annika Hillers, Eurídice N. Honorio Coronado, Cang Hui, Hyunkook Cho, Thomas Ibanez, Ilbin Jung, Nobuo Imai, Andrzej M. Jagodzinski, Bogdan Jaroszewicz, Vivian Johannsen, Carlos A. Joly, Tommaso Jucker, Viktor Karminov, Kuswata Kartawinata, Elizabeth Kearsley, David Kenfack, Deborah Kennard, Sebastian Kepfer-Rojas, Gunnar Keppel, Mohammed Latif Khan, Timothy Killeen, Hyun Seok Kim, Kanehiro Kitayama, Michael Köhl, Henn Korjus, Florian Kraxner, Diana Laarmann, Mait Lang, Simon Lewis, Huicui Lu, Natalia Lukina, Brian Maitner, Yadvinder Malhi, Eric Marcon, Beatriz Schwantes Marimon, Ben Hur Marimon-Junior, Andrew Robert Marshall, Emanuel Martin, Olga Martynenko, Jorge A. Meave, Omar Melo-Cruz, Casimiro Mendoza, Cory Merow, Stanislaw Miscicki, Abel Monteagudo Mendoza, Vanessa Moreno, Sharif A. Mukul, Philip Mundhenk, Maria G. Nava-Miranda, David Neill, Victor Neldner, Radovan Nevenic, Michael Ngugi, Pascal A. Niklaus, Jacek Oleksyn, Petr Ontikov, Edgar Ortiz-Malavasi, Yude Pan, Alexander Parada-Gutierrez, Elena Parfenova, Minjee Park, Marc Parren, Narayanaswamy Parthasarathy, Pablo L. Peri, Sebastian Pfautsch, Oliver L. Phillips, Maria Teresa Piedade, Daniel Piotto, Nigel C. A. Pitman, Martina Pollastrini, Irina Polo, Axel Dalberg Poulsen, John R. Poulsen, Freddy Ramirez Arevalo, Zorayda Restrepo-Correa, Mirco Rodeghiero, Samir Rolim, Anand Roopsind, Francesco Rovero, Ervan Rutishauser, Purabi Saikia, Christian Salas-Eljatib, Peter Schall, Dmitry Schepaschenko, Michael Scherer-Lorenzen, Bernhard Schmid, Jochen Schöngart, Eric B. Searle, Vladimír Seben, Federico Selvi, Josep M. Serra-Diaz, Douglas Sheil, Anatoly Shvidenko, Javier Silva-Espejo, Marcos Silveira, James Singh, Plinio Sist, Ferry Slik, Bonaventure Sonké, Alexandre F. Souza, Hans ter Steege, Krzysztof Stereńczak, Jens-Christian Svenning, Miroslav Svoboda, Ben Swanepoel, Natalia Targhetta, Nadja Tchebakova, Raquel Thomas, Elena Tikhonova, Peter Umunay, Vladimir Usoltsev, Renato Valencia, Fernando Valladares, Fons van der Plas, Tran Van Do, Michael E. Van Nuland, Rodolfo Vasquez Martinez, Hans Verbeeck, Helder Viana, Alexander C. Vibrans, Simone Vieira, Klaus von Gadow, Hua-Feng Wang, James Watson, Gijsbert D. A. Werner, Florian Wittmann, Verginia Wortel, Roderick Zagt, Tomasz Zawila-Niedzwiecki, Chunyu Zhang, Xiuhai Zhao, Zhi-Xin Zhu, Irie Casimir Zo-Bi, Daniel S. Maynard, Thomas W. Crowther

“…The extent to which traits of dominant and rare tree species differ remains untested across a broad environmental range, limiting our understanding of how species traits and the environment shape forest functional composition. …”
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Multi‐omics profiling identifies TNFRSF18 as a novel marker of exhausted CD8⁺ T cells and reveals tumour‐immune dynamics in colorectal cancer by Tengfei Jia, Yingxi Guo, Xin meng Cheng, Zeyang Zhou, Xiaojiang Xu, Hebin Liu, Xiaodong Yang

“…Ribosomal stemness in tumour cells promotes immune evasion by impairing TNF‐mediated CD8+ T cell function.…”
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Global Admittance: A New Modeling Approach to Dynamic Performance Analysis of Dynamic Vibration Absorbers by Cuauhtémoc Mazón-Valadez, Eduardo Barredo, Jorge Colín-Ocampo, Javier A. Pérez-Molina, Demetrio Pérez-Vigueras, Ernesto E. Mazón-Valadez, Agustín Barrera-Sánchez

“…In this work, global admittance functions are determined by the independent analysis of the mechanical networks of the DVA, restructuring the process of obtaining the system’s transfer function. …”
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‘They don’t squeal, ‘Disabled’.’: using qualitative interviews to explore user perceptions of ‘stylish’ grab rails intended to promote healthy ageing in place in England... by Katie Brittain, Kate Gibson, Sarah Dickson, Andrew Kingston, Mitra Cheraghi

“…However, some participants were unaware that the grab rails had been designed with a duality of purpose or were apprehensive towards the functionality of these grab rails. This apprehension may have stemmed from the home adaptations being provided by a large energy provider, or because the discreet design of the grab rails made their intended purpose less overt.Conclusions While home adaptations with a discreet and stylish aesthetic are valued by older people, our findings highlight that there are issues with commodifying home adaptations. …”
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Invited review: Ruminal acidosis and its definition—A critical review by H.M. Golder, I.J. Lean

“…ABSTRACT: Ruminal acidosis occurs as a continuum of disorders, stemming from ruminal dysbiosis and disorders of metabolism, of varying severity. …”
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Accelerated cassava varietal turnover in Tanzania, a direct result of cassava seed system interventions by Jessey A. Msami, Mathias Ndalahwa, Jonas Nickas, Maria Arbogast, James Nkwabi, Nsajigwa Mwakyusa, Ambilikile Mwenisongole, Dwasi Matondo, P. Lava Kumar, James P. Legg

“…The cassava seed system has been historically neglected resulting in the widespread propagation of poor quality and diseased planting materials (stems/cuttings). Recently there have been ongoing efforts to modernise cassava breeding and improve seed delivery in Tanzania which have resulted in the creation of a functional and commercially sustainable cassava seed system. …”
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Identification of matrix stiffness-related molecular subtypes in HCC via integrating multi-omics analysis and machine learning algorithms by Hanqi Li, Jiayi Zhang, Yu Shi, Huanhuan Wang, Ruida Yang, Shaobo Wu, Yue Li, Xue Yang, Qingguang Liu, Liankang Sun

“…Furthermore, increased matrix stiffness was found to upregulate PPARG expression, promoting cell proliferation, activating lipid metabolism, and enhancing the stemness of HCC cells through the MAPK signaling pathway. …”
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Genome-wide identification of the P4ATPase gene family and its response to biotic and abiotic stress in soybean (Glycine max L.) by Jingjing Wei, Gaoyang Zhang, Huanhuan Lv, Saidi Wang, Xingyu Liu, Yanli Qi, Zhongke Sun, Chengwei Li

“…Tissue-specific expression profiles revealed that GmALAs were differentially expressed in roots, stems, seeds, flowers, nodules and leaves. The expression pattern of these genes appeared to be diverse in the different developmental tissues. …”
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