Characterization of bovine and ovine basal-out and apical-out ileum organoids by Ambre F. Chapuis, Tanith Harte, Daniel R. G. Price, Marc N. Faber, William M. Anderson, Barbara Shih, Jayne C. Hope, Jo Moore, David Smith

“…Organoids are three-dimensional stem cell-derived structures that differentiate into multiple cell types. …”
Get full text

Optogenetic approaches for neural tissue regeneration: A review of basic optogenetic principles and target cells for therapy by Davletshin Eldar, Sufianov Albert, Ageeva Tatyana, Sufianova Galina, Rizvanov Albert, Mukhamedshina Yana

Get full text

Genome-wide identification of SWEET gene family and functional analysis of BcSWEET1-2 associated with flowering in flowering Chinese cabbage (Brassica campestris) by Xinmin Huang, Liming He, Yuyao Chen, Yin Liu, Jinfeng Liu, Guangyuan Lu, Riyuan Chen, Yunna Zhu, Shiwei Song, Qinqin He

“…BcSWEET1-2 has been confirmed to be localized in the cell membrane and to function as a hexose transporter. Overexpression of BcSWEET1-2 in Arabidopsis promotes stem carbohydrate accumulation, upregulates flowering gene expression, enhances Arabidopsis stem elongation, and advances flowering time. …”
Get full text

Pan-cancer profiling of FZD2 as a prognostic biomarker: integrative multi-omics analysis with experimental validation and functional characterization in gastric cancer by Sijiang Zhou, Sijiang Zhou, Sijiang Zhou, Sijiang Zhou, Da Li, Da Li, Da Li, Da Li, Chao Quan, Chao Quan, Zhu Yu, Zhu Yu, Zhu Yu, Yue Feng, Yue Feng, Yue Feng, Yue Feng, Shengyu Wang, Shengyu Wang, Shengyu Wang, Shengyu Wang, Yong Li, Yong Li, Yong Li, Yong Li, Tongtong Qi, Tongtong Qi, Tongtong Qi, Tongtong Qi, Junqiang Chen, Junqiang Chen, Junqiang Chen, Junqiang Chen

“…Additionally, single-cell analysis was employed to examine FZD2 expression levels across different cell types. To investigate the functional impact of FZD2, loss-of-function experiments were carried out in gastric cancer cell lines using siRNA-mediated knockdown. …”
Get full text

Hyperbaric oxygen promotes both the proliferation and chemosensitization of glioblastoma cells by inhibiting HIF1α/HIF2α-ABCG2 by Sheng Gong, Pan Wang, Bin Liao, Lu Zhao, Nan Wu

“…Gain-and loss-of-function experiments suggested that ABCG2 can promote the expression of stem cell marker proteins, inhibit cell apoptosis, and promote tumor progression.ConclusionThis study confirmed that hyperbaric oxygen can inhibit ABCG2 expression through HIF1α and HIF2α, thereby promoting the proliferation and chemosensitization of gliomas.…”
Get full text

Experimental study on the biomechanical loading of a four-dimensional plate for the fixation of femoral shaft fractures by Meiling Song, Jian Wen, Zhe Wang, Yu Zeng, Jun Lu, Wei Lu, Changsheng Chen, Xieping Dong

Get full text

Circadian rhythm defects in Prader-Willi syndrome neurons by A. Kaitlyn Victor, Tayler Hedgecock, Chidambaram Ramanathan, Yang Shen, Andrew C. Liu, Lawrence T. Reiter

“…Here, we investigated the circadian clock function in neurons derived from dental pulp stem cells (DPSCs) of PWS patients and neurotypical controls. …”
Get full text

HIV Protein TAT Dysregulates Multiple Pathways in Human iPSCs-Derived Microglia by Liam Liyang Guo, Robert Jiang, Yan Cheng, Brooke Russell, Sanders Y. Yan, Ming-Lei Guo

“…However, due to the significant species differences between rodent and human Mg (hMg), it is essential to take caution when interpreting the results obtained from rodent models into human conditions. …”
Get full text

From inserts to chips: microfluidic culture and 3D astrocyte co-culture drive functional and transcriptomic changes in hiPSC-derived endothelial cells by Tuuli-Maria Sonninen, Sanni Peltonen, Sara Kälvälä, Hoang-Tuan Nguyen, Marika Ruponen, Prateek Singh, Šárka Lehtonen

“…We aimed to investigate how different culture platforms alter the functionality and, consequently, the transcriptomic phenotype of hiPSC-derived endothelial cells (ECs). …”
Get full text

Carbamazepine does not alter the intrinsic cardiac function in rats with epilepsy Carbamazepina não altera o funcionamento cardíaco intrínseco em ratos com epilepsia by Diego B Colugnati, Ricardo M Arida, Roberta M Cysneiros, Vera C Terra, Eliza Y.F Sonoda, Aline P Pansani, Carla A Scorza, Esper A Cavalheiro, Fulvio A Scorza

Get full text

Astrocytes Differentiated from LRRK2-I1371V Parkinson’s-Disease-Induced Pluripotent Stem Cells Exhibit Similar Yield but Cell-Intrinsic Dysfunction in Glutamate Uptake and Metaboli... by Roon Banerjee, Aishwarya Raj, Chandrakanta Potdar, Pramod Kumar Pal, Ravi Yadav, Nitish Kamble, Vikram Holla, Indrani Datta

Get full text

Adsorptive removal of heavy metal ions from model aqueous media using titanium metal-organic framework and its polyvinyl chloride functionalized composite by Abdul Naeem, Naila Masood, Tooba Saeed, Bashir Ahmad, Muhammad Farooq, Tabassum Malik, Gul-e-Rana Jamil

“…For achieving this purpose, the solvothermal method was used to synthesis Ti-MOF which was then functionalized with PVC for composite synthesis. The synthesized adsorbent materials were then analyzed via different techniques that include the FTIR, XRD, SEM and EDX analysis along with TGA and point of zero charge (PZC). …”
Get full text

Facile fabrication of selegiline-loaded alginate hydrogel for neuroprotection and functional recovery in a rat model of spinal cord injury through localized spinal delivery by Ramin Abrishami, Ramtin Farhadi, Mehri Farhang Ranjbar, Seyed Hadi Aghili, Maryam Baeeri

“…These effects have triggered investigations into its impact on different neuron-associated disorders and SCI. Thus, in continuation of the previous studies, this study evaluates the local therapeutic effects of selegiline-loaded alginate hydrogel on SCI by analyzing apoptotic factors, histological factors, and improvements in locomotor function and neuropathic pain.Materials and Methods: Hydrogels were fabricated via cross-linking gelation method and characterized by FT-IR and SEM analysis. …”
Get full text

Identification and characterization of mRNAs of receptor-like kinases MhyGSO1 and MhyGSO2 in flowering parasitic plant Monotropa hypopitys by A. V. Shchennikova, E. Z. Kochieva, A. V. Beletsky, M. A. Filyushin, O. A. Shulga, N. V. Ravin, K. G. Skryabin

Get full text

Enhancing the nutritional profile of purple sweet potato flour through fermentation with Lactiplantibacillus plantarum InaCC B157: A functional food perspective by Tiurma Pasaribu, Yati Sudaryati Soeka, Novik Nurhidayat, Suciatmih Suciatmih, Titin Yulinery, Evi Triana, Tri Ratna Sulistiyani, Ninik Setyowati, Desty Dwi Sulistyowati, Dwi Ningsih Susilowati

“…Antioxidant activity increased by 13.7%. SEM analysis revealed no substantial morphological differences between FIB and UIB. …”
Get full text

Genome-wide identification of CAMTA gene family in teak (Tectona grandis) and functional characterization of TgCAMTA1 and TgCAMTA3 in cold tolerance by Wenlong Zhou, Jian Du, Runjie Jiao, Xianbang Wang, Tiansong Fang, Guihua Huang

“…Expression analysis of different tissues revealed the expression of TgCAMTA genes in teak roots, stems, leaves, flowers, fruits, and branches. …”
Get full text

Modern strategies for study of tumor’s markers in clinical practic by I. B. Zborovskaya

Get full text

Differentially expressed genes of SHED based on RNA-seq analysis after long-term expansion in vitro by WANG Huihui, WU Qing, ZHAO Yumei

“…[Objective:] To investigate the differences in gene expression of stem cells derived from human exfoliated deciduous teeth (SHED) after long-term continuous subculture to passage 20 (P20) in vitro by RNA sequencing (RNA-seq) analysis technology, and to preliminarily explore their signaling pathways related to in vitro expansion and aging. …”
Get full text

Activated Biocarbons Based on <i>Salvia officinalis</i> L. Processing Residue as Adsorbents of Pollutants from Drinking Water by Joanna Koczenasz, Piotr Nowicki, Karina Tokarska, Małgorzata Wiśniewska

“…This study presents research on the production of activated biocarbons derived from herbal waste. Sage stems were chemically activated with two activating agents of different chemical natures—H₃PO₄ and K₂CO₃—and subjected to two thermal treatment methods: conventional and microwave heating. …”
Get full text

Tuning Ru/Ni sites in the perovskite-based precursor synthesis to make more efficient and durable dual-function materials for integrated CO2 capture and methanation by Jon A. Onrubia-Calvo, Beñat Pereda-Ayo, Unai De-La-Torre, José A. González-Marcos, Juan R. González-Velasco

“…A new generation of Dual Function Materials (DFMs) were obtained after the controlled reduction of 20 % La0.6Ca0.4Ni0.95Ru0.05O3/CeO2 synthesized combining citric acid-wetness impregnation methods. …”
Get full text