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Targeting pivotal amino acids metabolism for treatment of leukemia
Published 2024-12-01Get full text
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Epigenetic regulation of organ-specific functions in Mikania micrantha and Mikania cordata: insights from DNA methylation and siRNA integration
Published 2024-11-01“…However, the role of DNA methylation in regulating the organ-specific functions of the invasive weed Mikania micrantha remains unknown. …”
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663
Functions of developmental pluripotency-associated 2 and 4 (DPPA2/DPPA4) in bovine preimplantation embryo development and their potential mechanisms
Published 2023-04-01“…Developmental pluripotency-associated 2 and 4 (DPPA2/DPPA4) are important regulators of genome activation in 2-cell-like embryonic stem cells (2CL ESCs), meanwhile, they can regulate the proliferation of ESCs. …”
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Interactions among Merlin, Arkadia, and SKOR2 mediate NF2-associated human Schwann cell proliferation
Published 2025-04-01“…Although the exactly molecular mechanism mediating NF2-driven schwannomatosis is not fully understood, it is known that defective Merlin protein functionality leads to abnormal cell proliferation. Methods Herein, we utilized a human induced pluripotent stem cell (hiPSC)-based Schwann cell (SC) model to investigate the role of Merlin in human SCs. …”
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Bone marrow sympathetic neuropathy is a hallmark of hematopoietic malignancies and it involves severe ultrastructural damage
Published 2025-03-01“…Abstract The hematopoietic stem cell (HSC) niche in the bone marrow (BM) supports HSC function, fate and numbers [1]. …”
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667
PrPC Glycoprotein Is Indispensable for Maintenance of Skeletal Muscle Homeostasis During Aging
Published 2025-02-01“…Methods This study investigated the change in PrPC expression during muscle formation using C2C12 cells and evaluated muscle function in Prnp wild‐type (WT) and knock‐out (KO) mice at different ages (1, 9 and 15 months). …”
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Influence of matrix nature on the functional efficacy of biomedical cell product for the regeneration of damaged liver (experimental model of acute liver failure)
Published 2017-06-01“…A statistically significant difference was found between the functional efficacy of the BMCP studied based on BNCM and BMCH matrices. …”
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Engineered iNKNKG2A KO cells possess HLA-E specific anti-tumor activity
Published 2025-05-01“…Objective To target at the NKG2A-HLA-E inhibitory axis, a pluripotent stem cell(iPSC)-derived genetically engineered natural killer cells(NK cells) with NKG2A knockout (NKG2A KO-iNK) were prepared and then their tumor-killing efficacy was evaluated in vitro. …”
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Predictive Role of Species Diversity on Aboveground Carbon via Functional Diversity and Dominance in the Moist Afromontane Forest: Implications for Conservation Policies
Published 2024-01-01“…Structural equation models (SEMs) were employed to assess the effects of species diversity, functional diversity, and functional dominance on AGC. …”
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Individualized resting-state functional connectivity abnormalities unveil two major depressive disorder subtypes with contrasting abnormal patterns of abnormality
Published 2025-02-01“…However, the clinical heterogeneity, likely stemming from diverse neurobiological disturbances, complicates findings from standard group comparison methods. …”
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The impact of various calcium ion sources on the curing efficacy of MICP
Published 2025-03-01“…The microstructure of the treated sand samples was analyzed using scanning electron microscopy (SEM) and X-ray diffraction (XRD). Elemental analysis was conducted via energy dispersive spectroscopy (EDS), and functional groups were identified through Fourier transform infrared spectroscopy (FTIR). …”
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Glucofuranose as corrosion inhibitor in API 5 L X70 steel immersed in NaCl 3 % by different hydrodynamic conditions and theoretical study
Published 2025-09-01“…Also, Langmuir isotherm shows that the glucofuranose presented a chemical adsorption process at different rotation rates. According to the SEM-EDS analysis, the metal's protection is evidenced by the formation of a α-D-glucofuranose monolayer on its surface, which isolates it from the corrosive environment. …”
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