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Serum indicators in functional high-risk multiple myeloma patients undertaking proteasome inhibitors therapy: a retrospective study
Published 2024-12-01“…An increasing application of autologous stem cell transplantation (ASCT) and anti-myeloma agents represented by proteasome inhibitors (PIs) has improved the response rates and survival of MM patients. …”
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642
Adaptation of the Upper Limb Functional Index (ULFI) to a Polish version and validation in patients with upper limb musculoskeletal disorders
Published 2025-05-01“…Abstract Background The Upper Limb Functional Index (ULFI) is a robust, widely used tool for assessing the functional status of the upper limbs (ULs) and the effectiveness of interventions in patients with musculoskeletal disorders (MSDs). …”
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643
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Identification and Functional Characterization of Alfalfa (<i>Medicago sativa</i> L.) Expansins in Regulating Arabidopsis Shoot and Root Development
Published 2024-10-01“…Furthermore, expression analysis suggested that <i>MsEXP</i> genes exhibited distinct expression patterns among different tissues of alfalfa. Overexpression of <i>MsEXPA3</i> or <i>MsEXPA4</i> promoted the growth of leaves, stems and roots of Arabidopsis, thereby increasing the biomass of plants. …”
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645
Climate is stronger than you think: Exploring functional planting and TRIAD zoning for increased forest resilience to extreme disturbances.
Published 2025-01-01“…It's uncertain whether these results stemmed from the relative lack of small-scale interactions in LANDIS-II through which the effect of functional diversity on stand resilience should occur, or if this effect is small to begin with. …”
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646
When Genetic Diversity Is Low: The Effects of Ploidy Level on Plant Functional Trait Expression in Spartina Under Global Change
Published 2025-03-01“…The allopolyploid's comparatively fewer, larger‐diameter stems may affect aboveground ecosystem functions differently, including sediment trapping and the slowing of tidal currents. …”
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647
Hypoxia-derived mesenchymal stem-cell exosomes delivering naringin enhance osteoblast migration and fracture healing by upregulating integrin β1 via the BDNF-TrkB/ERK1/2 signaling...
Published 2025-04-01“…Background: The paracrine mechanism of mesenchymal stem cells (MSCs) is receiving extensive attention, and exosomes are positioned as the key mediators. …”
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648
Generation of INS-jGCaMP7f knock-in Ca2+ reporter human embryonic stem cell line, GZLe001-C, using CRISPR/Cas9-based gene targeting
Published 2025-02-01“…The reporter cell line not only effectively labelled the insulin-producing cells induced from hESC, but also reflected the cytosolic change of Ca2+ level in response to different stimuli. This reporter cell line is a valuable research tool for studying functional maturation of hESC-derived insulin-producing cells, conducting drug screenings, and exploring the mechanisms of diabetes.…”
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Mesenchymal stromal cells (MSC) from JAK2+ myeloproliferative neoplasms differ from normal MSC and contribute to the maintenance of neoplastic hematopoiesis.
Published 2017-01-01“…In the current work we have compared the function and gene expression profile of BM-MSC from healthy donors (HD-MSC) and patients with MPN (JAK2V617F), showing no differences in the morphology, proliferation and differentiation capacity between both groups. …”
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651
Experimental Investigation of the Mechanical and Structural Properties of a Functionally Graded Material by Adding Alumina Nanoparticles Using A Centrifugal Technique
Published 2023-10-01“… In this work, functionally graded materials were synthesized by centrifugal technique at different volume fractions 0.5, 1, 1.5, and 2% Vf with a rotation speed of 1200 rpm and a constant rotation time, T = 6 min . …”
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652
Comparison of Structural, Physicochemical, and Functional Properties of Blueberry Residue Dietary Fiber Extracted by Wet Ball Milling and Cross-Linking Methods
Published 2025-03-01“…Scanning electron microscopy (SEM) demonstrated that WB treatment unfolded the flaky structure of DF and caused more pores to occur. …”
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Influence of chemical concentrations on the physicochemical, structural, functional and color characteristics of chitin isolated from Arabian red shrimp (Aristeus alcocki)
Published 2025-06-01“…Morphological analysis using FE-SEM revealed a smooth, porous and microfibrillar structure in the isolated chitin samples. …”
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656
Intravenous injection of BMSCs modulate tsRNA expression and ameliorate lung remodeling in COPD mice
Published 2024-11-01“…Abstract Background Chronic obstructive pulmonary disease (COPD) is characterized by lung remodeling induced by chronic inflammation, presenting challenges for effective treatment. Mesenchymal stem cells (MSCs) and their extracellular vesicles (EVs) have shown promise in mitigating inflammation and tissue repairing in various diseases, including COPD. …”
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657
Synthesis of Ficus carica sap-functionalized Nano-chitosan for biomedical applications: Apoptosis induction and tumor cell line growth inhibition
Published 2025-03-01“…In the present study, Chitosan-ficus carica sap nanocomposite was synthesized and The structural properties and morphology of functionalized Nano-chitosan were investigated using FTIR, SEM, and TEM analysis. …”
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658
Development and evaluation of folic acid conjugated curcumin-loaded functionalized multiwalled carbon nanotubes for enhanced efficacy in ovarian cancer treatment
Published 2025-04-01“…CUR was loaded onto MWCNT-COOH using the direct method, and then FA conjugation was performed. Using different techniques, such as Fourier transform infrared (FTIR) spectroscopy, Field emission scanning electron microscopy (FE-SEM), Differential light scattering (DLS), Proton Nuclear Magnetic Resonance (1HNMR) spectroscopy, Raman spectroscopy, X-Ray diffraction (XRD), the curcumin-loaded MWCNTs (CUR-MWCNT-COOH) and the FA-bound formulation (CUR-MWCNT-COOH-FA) were analyzed. …”
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659
Microfluidic chip systems for characterizing glucose-responsive insulin-secreting cells equipped with FailSafe kill-switch
Published 2024-12-01“…Subsequently we evaluated and confirmed the functionality of the drug-inducible kill-switch in FSβiPLCs at different ganciclovir (GCV) concentrations using our PDMS-based transcapillary microfluidic system. …”
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660
Long noncoding RNA as an emerging regulator of endoderm differentiation: progress and perspectives
Published 2025-03-01“…In this review, we have analyzed the features of overlapping, proximal, and desert lncRNAs, classified by genomic location, in pluripotent stem cells (PSCs) and the differentiation derivatives. …”
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