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481
Human spindle-shaped urine-derived stem cell exosomes alleviate severe fatty liver ischemia–reperfusion injury by inhibiting ferroptosis via GPX4
Published 2025-02-01“…Abstract Background Severe hepatic steatosis can exacerbate Ischemia–reperfusion injury (IRI), potentially leading to early graft dysfunction and primary non-function. In this study, we investigated the heterogeneity of different subpopulations of Urine-derived stem cells (USCs) to explore the most suitable cell subtype for treating severe steatotic liver IRI. …”
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482
Effects of Human Mesenchymal Stem Cells Isolated from Wharton’s Jelly of the Umbilical Cord and Conditioned Media on Skeletal Muscle Regeneration Using a Myectomy Model
Published 2014-01-01“…The in vivo application of human mesenchymal stem cells (HMSCs) of the umbilical cord and the conditioned media (CM) where the HMSCs were cultured and expanded, associated with different vehicles to induce muscle regeneration, was evaluated in a rat myectomy model. …”
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483
Diversity of Antifungal Properties in Bacterial Isolates from Different Plant Species Growing Across Uzbekistan
Published 2025-05-01“…To investigate the competitive dynamics between phytopathogenic fungi and plant-associated bacteria, we collected stem and root samples from 50 plant species across nine regions of Uzbekistan. …”
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484
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485
Thermal and functional properties of starch extracted from tubers cultivated in the Ecuadorian Andean region
Published 2021-07-01“…Thermal and functional properties of starch extracted from American taro and Indian shot were determined to assess their use in food products. …”
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486
Characteristics and nutritional value of cookies fortified with debittered salmon (Salmo salar) frame protein hydrolysate
Published 2025-03-01“…SEM analysis confirmed a denser matrix and less voids in cookies added with DSF-PH. …”
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487
Assessing the Effect of Fatigue on Swallowing Function in Adults with Acute Stroke. A Pilot Study
Published 2024-12-01Get full text
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488
Elevated TIM3 expression on bone marrow T cells drives immune dysfunction in early relapsed blood cancer after allogeneic hematopoietic stem cell transplantation
Published 2025-08-01“…Abstract Relapse after allogeneic hematopoietic stem cell transplantation (allo-HSCT) remains the leading cause of treatment failure in patients with hematologic malignancies. …”
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489
Cell biobank as a necessary infrastructure for the development and implementation of mesenchymal stem cell-based therapy in the treatment of anthracycline-induced cardiotoxicity. L...
Published 2020-12-01“…With the introduction of molecular and cell biology into medical practice, today, stem cell therapy can become an alternative method of nonsurgical restoration of myocardial functions. …”
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490
Mesenchymal stem cell-derived extracellular vesicles attenuate periductal fibrosis by inhibiting Th17 differentiation in human liver multilineage organoids and Mdr2−/− mice
Published 2025-07-01“…Here, we develop a novel human liver multilineage organoid (Mulorg) model combined with Mdr2−/− mice to investigate the pro-fibrotic role of T helper 17 cells (Th17) and the therapeutic potential of mesenchymal stem cell-derived extracellular vesicles (EVMSC) for PSC, particularly periductal fibrosis. …”
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491
Wnt-signaling pathway in pathogenesis of glioblastoma multiforme
Published 2019-01-01“…The Wnt-signaling pathway regulates various biological processes, such as embryonic development, self-renewal, proliferation, differentiation and migration of stem cells. The Wnt-signaling is involved in tumor progression by aberrant activation in stem-like cells, called cancer stem cells, in different kinds of tumor, including multiform glioblastoma. …”
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492
Collagen-based biomaterials: recent advances on regulating cell migration and correlated biomedical applications
Published 2025-06-01“…The discussion primarily focuses on three pivotal cell types: stem cells, immune cells, and cancer cells. By shedding light on the functions, mechanisms, and therapeutic potential of collagen in cell migration, this review will contribute to the development of innovative collagen-based biomaterials with applications in wound healing and tissue regeneration. …”
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493
Cellular crosstalk in the bone marrow niche
Published 2024-12-01“…Abstract The bone marrow niche is a special microenvironment that comprises elements, including hematopoietic stem cells, osteoblasts, and endothelial cells, and helps maintain their characteristic functions. …”
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494
Cryopreservation and culture strategies for testicular tissue and cells in small and large animals
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495
Unveiling the signal valve specifically tuning the TGF-β1 suppression of osteogenesis: mediation through a SMAD1-SMAD2 complex
Published 2025-01-01“…In vivo adipogenesis and ex vivo culture of bone explants were used to verify the functions of different SMAD complexes. Ingenuity Pathway Analysis, and analysis of transcriptomic datasets from human BM-MSCs in combination with hierarchical clustering and STRING assay were used to decipher the interplaying co-repressors. …”
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496
Cell therapy efficacy and safety in treating tendon disorders: a systemic review of clinical studies
Published 2022-01-01“…For Achilles tendinopathies, only one randomized controlled trial (RCT) found that both cell therapy and control groups showed significant pain reduction and functional improvement with no statistical differences at the 6 months follow‐up, but the cell therapy group had improved faster at earlier follow‐ups. …”
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497
Genome-wide identification and functional analysis of the GRAS gene family in Medicago lupulina L
Published 2025-07-01“…To further predict the potential functions of MlPAT1s genes, we performed molecular cloning and transcriptional activation assays on MlGRAS3/31/35/62/65. …”
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498
Development and analysis of scaffold-free adipose spheroids
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499
Comparative Analysis of Endophytic <i>Curtobacterium</i> Species Reveals Commonalities and Adaptations
Published 2025-05-01“…<i>Curtobacterium</i> species are increasingly recognized as plant pathogens and soil decomposers, but their prevalence and function as plant endophytes in aerial organs are less clear. …”
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500
Bioinformatics-Based Analysis of Ferroptosis-Related Biomarkers and the Prediction of Drugs Affecting the Adipogenic Differentiation of MSCs
Published 2025-04-01“…<b>Background</b>: The imbalance between the osteogenic and adipogenic differentiation of mesenchymal stem cells (MSCs) is a key factor in the progression of osteoporosis; therefore, it is crucial to study the regulatory mechanisms that maintain this balance. …”
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