Simultaneous profiling of classic and 11-oxygenated androgens via a novel derivatization method coupled with HPLC-MS/MS: A game-changer for endocrine disorders by Xianhua Zhang, Huiyu Xu, Yue Sun, Xin Xiong, Lingling Liu, Li Yang, Libo Zhao, Xiaona Li, Rong Li, Rongsheng Zhao

“…The linear ranges for different targets were set based on clinical use and the lower limit of quantification (LLOQ) of the target androgens ranged from 0.005 to 1 ng/mL. …”
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Predicting future evapotranspiration based on remote sensing and deep learning by Xin Zheng, Sha Zhang, Shanshan Yang, Jiaojiao Huang, Xianye Meng, Jiahua Zhang, Yun Bai

“…Study focus: This study validates the efficiency of Convolutional Long Short-Term Memory Network (ConvLSTM) models for site-scale ETa prediction. …”
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Quantification of Total and Unbound Selinexor Concentrations in Human Plasma by a Fully Validated Liquid Chromatography-Tandem Mass Spectrometry Method by Suhyun Lee, Seungwon Yang, Hyeonji Kim, Wang-Seob Shim, Eunseo Song, Seunghoon Han, Sung-Soo Park, Suein Choi, Sungpil Han, Sung Hwan Joo, Seok Jun Park, Beomjin Shin, Donghyun Kim, Hyeon Su Kim, Kyung-Tae Lee, Eun Kyoung Chung

“…Unbound selinexor was separated using ultrafiltration, and selinexor was efficiently extracted from 50 μL of plasma by liquid–liquid extraction. …”
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Phenological Performance, Thermal Demand, and Qualitative Potential of Wine Grape Cultivars Under Double Pruning by Carolina Ragoni Maniero, Marco Antonio Tecchio, Harleson Sidney Almeida Monteiro, Camilo André Pereira Contreras Sánchez, Giuliano Elias Pereira, Juliane Barreto de Oliveira, Sinara de Nazaré Santana Brito, Francisco José Domingues Neto, Sarita Leonel, Marcelo de Souza Silva, Ricardo Figueira, Pricila Veiga dos Santos

“…These results highlight the enological potential of the evaluated cultivars and confirm the efficiency of the double-pruning system in improving grape composition and wine quality in non-traditional viticultural regions.…”
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Simultaneous Down-Regulation of Dominant Cinnamoyl CoA Reductase and Cinnamyl Alcohol Dehydrogenase Dramatically Altered Lignin Content in Mulberry by Shuai Huang, Xiaoru Kang, Rumeng Fu, Longyan Zheng, Peijun Li, Fengjuan Tang, Nan Chao, Li Liu

“…The down-regulation of <i>MaCCR1</i> and <i>MaCAD3/4,</i> both individually and concurrently, exhibited markedly different effects on lignin content and mulberry growth. …”
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Machine learning-guided field site selection for river classification by Zhihao Wang, Gregory Brian Pasternack, Yufang Jin, Costanza Rampini, Serena Alexander, Nikhil Kumar, Rune Storesund, K. Martin Perales, Christopher Lim, Stephanie Moreno, Igor Lacan

“…Machine learning has been recognized for discovering and extracting streams’ geomorphic patterns efficiently and accurately from data, but its application in field site sampling design is still in its infancy. …”
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Versatile enhancement of the killing potential of anti-cancer agents achieved by peptide mimetics of the PCNA interface towards specialized DNA polymerases by Yiovana Verónica Okraine, María Belén de la Vega, Sofía Venerus Arbilla, Ginette Moyano, Agostina P. Bertolin, Horacio M. Pallarés, Lisa Wiesmüller, Sabrina F. Mansilla, Vanesa Gottifredi

“…This strategy is demonstrably valid to enhance the cancer cell killing by different DNA-damaging agents.…”
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Digestion kinetics of protein feed ingredients and their impact on nitrogen utilization in growing pigs by Jia Li, Yu Cao, Xiaoyi Yu, Jingyi Huang, Rouke Jiang, Mingyi Huang, Jinbiao Zhao, Dandan Han, Junjun Wang

“…The velocity of nitrogen release impacts nitrogen utilization efficiency and animal growth. Yet the crucial junctures linking nitrogen release and utilization from diverse feed ingredients to digestion kinetic parameters remain obscure. …”
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Analytical comparisons of SARS-COV-2 detection by qRT-PCR and ddPCR with multiple primer/probe sets by Xinjin Liu, Jiangpeng Feng, Qiuhan Zhang, Dong Guo, Lu Zhang, Tao Suo, Wenjia Hu, Ming Guo, Xin Wang, Zhixiang Huang, Yong Xiong, Guozhong Chen, Yu Chen, Ke Lan

“…Different primers/probes sets have been developed all over the world for the nucleic acid detection of SARS-CoV-2 by quantitative real time polymerase chain reaction (qRT-PCR) as a standard method. …”
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Comprehensive mitochondrial genomics of Fasciola gigantica from Sudan: insights into genetic diversity, evolutionary dynamics, and host adaptation by Bashir Salim, Nouh S. Mohamed, Kamal Ibrahim, Saeed Alasmari, Elisha Chatanga, Elisha Chatanga, Yuma Ohari, Nariaki Nonaka, Mohammad A. Alsaad, Faisal Almathen, Ryo Nakao, Ryo Nakao, Ryo Nakao

“…Length polymorphisms in ND4L and cox1 suggested potential mitochondrial efficiency adaptations. Non-coding regions showed minor length differences, with the long non-coding region extending by 20 bp and the short by 4 bp. …”
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Characteristics of the source material for breeding winter wheat for group resistance to leaf and stem pathogens by Є. А. Голуб, Н. І. Сауляк, О. А. Васильєв, М. А. Литвиненко, В. А. Трасковецька, З. В. Щербина, М. А. Бушулян, Є. І. Кірчук

“…Investigation of the efficiency of using introgressive lines with group resistance to leaf pathogens as source material in breeding winter wheat (Triticum aestivum L.) for the aforementioned trait. …”
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3-O-trans-p-coumaroyl esterification enhances the anti-inflammatory effects of tormentic acid by targeting NF-κB signaling by Mara Heckmann, Lea Karlsberger, Bernhard Blank-Landeshammer, Gerald Klanert, Nadiia Sadova, Verena Stadlbauer, Georg Sandner, Theresa Gramatte, Simone Kasis, Julian Weghuber

“…Pro-inflammatory cytokine production in LPS-stimulated THP-1 macrophages was analyzed through cytokine arrays and multiplex immunoassays, while NF-κB activation was examined in both TLR4-dependent and -independent models using HEK-Blue reporter cells. Uptake efficiencies into Caco-2 enterocytes were measured via LC-MS. …”
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Multiple-omics analysis of three novel haloalkaliphilic species of Kocuria revealed that the phenolic acid-degrading abilities are ubiquitous in the genus by Lian Xu, Lian Xu, Rui-Qi Sun, Jia-Hui Zeng, Hua-Mei Wei, Biao Shen, Ji-Quan Sun

“…All five Kocuria strains could efficiently degrade ferulic acid (FA) and cinnamic acid (CA) under saline-alkaline conditions. …”
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The role of transarterial chemoembolization with drug-eluting beads “Sphere-Spectrum” in the treatment of primary and recurrent tumors of the female reproductive system complicated... by E. A. Zvezdkina, A. G. Kedrova, D. P. Lebedev, T. A. Greyan, D. N. Panchenkov, Yu. A. Stepanova, S. E. Krasilnikov, K. S. Budennyy

“…To evaluate the effectiveness of TACE in tumors of the female reproductive system complicated by bleeding at different stages of the disease.Materials and methods. …”
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How and when do we use continuous renal replacement therapy for acute kidney injury in Serbia? - The multicentric survey by Knežević Violeta, Ćelić Dejan, Azaševac Tijana, Golubović Sonja, Sladojević Vesna, Nestorov Nataša, Maksić Đoko, Naumović Radomir, Lazarević Tatjana, Nešković Vojislava

“…The questionnaires were distributed among physicians of different specialties who participated voluntarily and anonymously. …”
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Effectiveness of using autologous platelet cryolysate after knee arthroscopy by S.I. Gerasymenko, M.V. Poluliah, A.M. Babko, A.S. Gerasymenko, D.M. Poluliah, R.M. Ostpchuk, D.S. Yarosh, O.M. Lushchii, N.Y. Marchenko

“…Given its regenerative potential, safety, and efficiency, APL represented a promising therapeutic approach.…”
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Study on catalytic oxidation of low concentration 14CH4 by non-thermal plasma by PEI Jianlu, LIANG Shuwei, LIN Zhongxin, LI Jiayu, CHEN Jianli, HAN Ming, HOU Jianrong, LI Yongguo

“…The CH4 treatment performance of the non-thermal plasma before and after the introduction of the catalyst under different discharge voltages, gas flow rates and temperatures were analyzed by the constructed experimental system. …”
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Right Ventricular Myocardial Work Predicts Pulmonary Capillary Wedge Pressure Rise During Exercise in Heart Failure by Kuan-Chih Huang, MD, PhD, Ting-Tse Lin, MD, PhD, Lung-Chun Lin, MD, PhD, Lian-Yu Lin, MD, PhD, Cho-kai Wu, MD, PhD

“…No significant differences in various echocardiographic parameters were found between HFpEF and non-HFpEF groups, except higher postexercise PCWP and mean pulmonary artery pressure in HFpEF patients. …”
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Effects of exogenous melatonin on photosynthetic and antioxidant properties of young seedlings under salt stress conditions in pomegranate by YANG Yuanling, LIU Huiying, GUAN Sihui, CHAI Yaqian, GAI Haosheng, LIU Mingxuan, LIU Yang, DIAO Ming

“…At 15 d of salt stress, application of exogenous MT at suitable concentrations (100 and 200 μmol·L-1) effectively enhanced net photosynthetic rate (Pn), transpiration rate (Tr), stomatal conductance (Gs), photochemical quenching coefficient (qP), actual photochemical efficiency (YⅡ), and maximal photochemical efficiency (Fv/Fm) in pomegranate leaves, and the Tunisian Soft-seeded pomegranate increased by 32.89%-45.06%, 16.40%-37.49%, 26.09%-53.10%, 0.41%-19.90%, 28.44%-48.04% and 11.89%-20.39%, respectively, and Yecheng Acid pomegranate increased by 28.81%-42.47%, 17.13%-34.06% 12.50%-37.78%, 2.94%-20.59%, 46.59%-48.58%, and 24.93%-32.00%, respectively. …”
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INVESTIGATION OF A ROLE OF THE IMMUNOGENICITY OF INFLIXIMAB IN THE THERAPY OF ANKYLOSING SPONDYLITIS by O. A. Rumyantseva, A. G. Bochkova, M. M. Urumova, M. V. Cherkasova, E. N. Aleksandrova, S. K. Solovyev, Sh. F. Erdes

“…Moreover, the serum concentration of INF was not significantly different in these groups (1.6 and 2.96 μg/ml). There was an inverse correlation  between INF concentrations and anti-INF antibodies (r = -0.7; p &lt; 0.05). …”
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