Mutation in CDC42 Gene Set as a Response Biomarker for Immune Checkpoint Inhibitor Therapy by Kun Wang, Yingying Zhang, Zhaoming Su, Bei Wang, Yuanyang Zhou, Xiaochu Tong, Chengying Xie, Xiaomin Luo, Sulin Zhang, Mingyue Zheng

“…Furthermore, our analysis of immune response landscapes among different statuses of the CDC42 gene set supports its role as a biomarker. …”
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Controllable synthesis of alumina nanofibers with tunable crystal phases via a facile and cost-effective dealloying process by Qianwen Sun, Zhenying Huang, Wenqiang Hu, Haozheng Han, Weici Zhuang, Xue Li, Youbo Wu, Xinkang Li, Ziqiang Zhu, Yang Zhou

“…We investigated the evolution of the alloy into nanofibers in dry ethanol and the influence of different Al‒Li alloy compositions and calcination temperatures on the crystal structure and morphology of the resulting Al2O3 nanofibers. …”
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Federated and ensemble learning framework with optimized feature selection for heart disease detection by Olfa Hrizi, Karim Gasmi, Abdulrahman Alyami, Adel Alkhalil, Ibrahim Alrashdi, Ali Alqazzaz, Lassaad Ben Ammar, Manel Mrabet, Alameen E.M. Abdalrahman, Samia Yahyaoui

“…Predictive models for early identification of heart disease must be precise and efficient because it is a major worldwide health concern. …”
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Detection of microplastics stress on rice seedling by visible/near-infrared hyperspectral imaging and synchrotron radiation Fourier transform infrared microspectroscopy by Chaojie Wei, Hongxin Xie, Hongxin Xie, Hongxin Xie, Wei Wang, Yu-Feng Li, Yu-Feng Li, Yu-Feng Li, Xiaorong Wang, Ziwei Song, Fajun Chen

“…In order to rapidly screen and diagnosis rice seedling under MPs stress at an early stage, it is essential to develop efficient and non-destructive detection methods.MethodsIn this study, rice seedlings exposed to different concentrations (0, 10, and 100 mg/L) of polyethylene terephthalate (PET), polystyrene (PS), and polyvinyl chloride (PVC) MPs stress were constructed. …”
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Physics-augmented deep learning models for improving evapotranspiration estimation in global land regions by Binrui Liu, Xinguang He, Wenkai Lyu, Lizhi Tao

“…These results confirm the potential of data-physics hybrid modeling in ET estimation, which is conducive to supporting efficient irrigation water management.…”
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Cefiderocol in Combating Carbapenem-Resistant <i>Acinetobacter baumannii</i>: Action and Resistance by Bahman Yousefi, Setayesh Kashanipoor, Payman Mazaheri, Farnaz Alibabaei, Ali Babaeizad, Shima Asli, Sina Mohammadi, Amir Hosein Gorgin, Tahereh Alipour, Valentyn Oksenych, Majid Eslami

“…Due to its unique structure, cefiderocol can more efficiently target and destroy resistant bacteria by using iron transport systems. …”
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Effects of straw mulching and plastic mulching on maize yield and crop water productivity in China: A meta-analysis by Xuegui Zhang, Yao Li, Yanan Sun, Lianyu Yu, Jiatun Xu, Xiaobo Gu, Huanjie Cai

“…This study employed meta-analysis to evaluate the effects of straw and plastic mulching on maize yield and WPc across different climatic zones, soil types, and agronomic practices in China. …”
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Robust machine learning models for calculating the carbon dioxide desublimation point within natural gas mixtures at low temperature conditions by Walid Abdelfattah, Munthar Kadhim Abosaoda, Dharmesh Sur, Menon Soumya V, Prabhat Kumar Sahu, Kamred Udham Singh, R. Sivaranjani, Rohit Chauhan, Siya Singla, Fereydoon Ranjbar

“…Desublimation at low temperatures offers an efficient method for removing CO2 from gas streams. …”
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Simulation-free cone beam CT-based online adaptive radiotherapy for metastatic spinal cord compression by Lisette Sandt, Evangelos Giannoulis, Laura Ann Rechner, Lina Åström, Anna Mann Nielsen, Jens Morgenthaler Edmund, Gitte Fredberg Persson

“…Combined with conebeam computed tomography (CBCT)-guided online adaptive radiotherapy (oART), this strategy has the potential to create a more efficient treatment workflow and reduce the burden for the patients. …”
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Quantitative evaluation of essential amino acids and omega-3 long-chain polyunsaturated fatty acids from global marine bivalve aquaculture by Karsoon Tan, Peng Xu, Leiheng Huang, Cong Luo, KhaiHang Choong, Zexin Li, Yu Guo, Kit-Leong Cheong

“…Current production levels of EPA + DHA and EAAs from bivalve aquaculture are sufficient to meet the dietary needs of 78.68 million and 17.3 million healthy adults, respectively. Among different bivalve species, clams and scallops are the most efficient producers of EPA + DHA and EAAs, while oysters produce the least. …”
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CD-STMamba: Toward Remote Sensing Image Change Detection With Spatio-Temporal Interaction Mamba Model by Shanwei Liu, Shuaipeng Wang, Wei Zhang, Tao Zhang, Mingming Xu, Muhammad Yasir, Shiqing Wei

“…In this article, we propose a CD Mamba model (CD-STMamba), which can efficiently encode and decode bitemporal images interactively from multiple dimensions, thus enabling more accurate CD. …”
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Development of a Liquid Chromatography–Tandem Mass Spectrometry Method for Oxylipin Analysis and Its Application to Children’s Plasma by Yonghan Li, Siddabasave Gowda B. Gowda, Divyavani Gowda, Atsuko Ikeda, Yu Ait Bamai, Rahel Mesfin Ketema, Reiko Kishi, Hitoshi Chiba, Shu-Ping Hui

“…Because of the numerous isomers of oxylipins, it is essential to develop efficient and precise analytical methods for their identification and quantification. …”
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A multi-modal deep learning solution for precise pneumonia diagnosis: the PneumoFusion-Net model by Yujie Wang, Yujie Wang, Can Liu, Yinghan Fan, Chenyue Niu, Wanyun Huang, Yixuan Pan, Jingze Li, Jingze Li, Yilin Wang, Jun Li, Jun Li, Jun Li

“…Five-fold cross-validation was considered in order to evaluate this model, calculating different metrics including accuracy and F1-Score.ResultsPneumoFusion-Net, which achieved 98.96% classification accuracy with a 98% F1-score on the held-out test set, is highly effective in distinguishing bacterial from viral types of pneumonia. …”
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Identification and Characterization of Antiviral Activity of Synthetic Compounds Against Mayaro Virus by Ana Paula Andreolla, Andrea Cristine Koishi, Alessandra Abel Borges, Larissa Albuquerque de Oliveira, Viviane Guedes de Oliveira, Nerilson Marques Lima, Eloah Pereira Ávila, Pedro Pôssa de Castro, Giovanni Wilson Amarante, Mauro Vieira de Almeida, Juliano Bordignon, Claudia Nunes Duarte dos Santos

“…Additionally, anti-MAYV activity of these four selected hits was confirmed using several human cell lines and two different MAYV genotypes. <b>Conclusions:</b> Our results indicate that the iHTS platform is effective for screening anti-MAYV drugs and that four promising compounds can efficiently inhibit MAYV replication in human cell lines. …”
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Pesticide effects of highly stable green synthesized silver nanocomposites to be used in organic tomato crops by Luis E. Trujillo, Pablo Landázuri, Carlos Noceda, José Velasco, Luz Toapanta, Giulliana Criollo, Andrea Poaquiza, Fulton Barros, Vladimir Aguirre, Andrés Izquierdo, Julio Chacón, Zailmar Morales, Alexis Debut

“…With this scalable one step synthesis, the obtained PVP-AgNPs nanocomposite showed particle sizes of 10.8 nm being highly stable during 326 days. At different assayed doses, this highly stable PVP-AgNPs nanocomposite, was able to control whitefly specimens efficiently with an average mortality rate of 98% after 10 days of the nanocomposite application to naturally infested tomato leaves grown under greenhouse conditions. …”
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Pathogen detection and antibiotic use in granulomatous lobular mastitis: a comparison of mNGS and culture by Xu Mu, Xu Mu, Hongmin Luo, Hanhua Li, Shenghua Chen, Shenghua Chen, Yuyang Han, Yuyang Han, Lin Zhang, Lin Zhang, Wei Liu, Weilong Qiao, Shaoyi Zheng, Zhifeng Huang, Zhifeng Huang, Zhifeng Huang

“…Additionally, surgical intervention remains the most efficient approach for rapid and complete resolution.…”
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<i>Megaselia scalaris</i> and <i>Senotainia tricuspis</i> Infesting <i>Apis mellifera</i>: Detection by Quantitative PCR, Genotyping, and Involvement in the Transmission of Microbi... by Franca Rossi, Martina Iannitto, Beqe Hulaj, Paola Manocchio, Francesca Gentile, Ilaria Del Matto, Massimiliano Paoletti, Lucio Marino, Luciano Ricchiuti

“…The <i>Megaselia scalaris</i> and <i>Senotainia tricuspis</i> parasitoid flies of the honeybee <i>Apis mellifera</i> were found to infest apiaries of different European and Mediterranean countries but their prevalence and impact on apiary health are little known. …”
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Most prominent challenges in translational neuroscience and strategic solutions to bridge the gaps: Perspectives from an editorial board interrogation by Dirk M. Hermann, Marco Bacigaluppi, Claudio L. Bassetti, Gabrio Bassotti, Johannes Boltze, Andrew Chan, Turgay Dalkara, Adam Denes, Exuperio Diez-Tejedor, Richard Dodel, Thorsten R. Doeppner, Egor Dzyubenko, Ayman ElAli, Tamas Fulop, Alexander Gerhard, Bernd Giebel, Janine Gronewold, Matthias Gunzer, Thomas Heinbockel, Kaibin Huang, Marcello Iriti, Hans-Otto Karnath, Kasteleijn-Nolst Trenite, Ertugrul Kilic, Giuseppe Lanza, Arthur Liesz, Tim Ullrich Magnus, Jessica Mandrioli, Ayan Mohamud-Yusuf, Thomas Müller, Suyue Pan, Luca Peruzzotti-Jametti, Stefano Pluchino, Ryszard Pluta, Aurel Popa-Wagner, Ameneh Rezayof, Mohamed L. Seghier, Xinhua Shu, Vikram Singh, Jussi Sipilä, Mark Slevin, Yamei Tang, Georgios Tsivgoulis, Giustino Varrassi, Chen Wang, Bayram Yilmaz, Maha S. Zaki, Jinwei Zhang

“…These challenges can be addressed through more clearly defined experimental procedures that closely match clinical conditions and precision-based approaches that ensure efficient therapeutic responses. As a great opportunity, treatment options targeting pathophysiological processes in multiple brain diseases and disease processes in different organ systems were noted. …”
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Microbial community succession during tobacco fermentation reveals a flavor-improving mechanism by Jingjing Zhu, Jingjing Zhu, Jitao Wang, Zichao An, Zichao An, Chen Shen, Hongxu Dong, Haojun Wang, Zhenxing Peng, Bo Yang, Juanjuan Liu, Juanjuan Liu, Xiaojie Wang, Xiaojie Wang, Zemin Fang, Zemin Fang

“…Artificial microbial fermentation, which is more controllable and efficient, focuses on mining functional strains to optimize the process.MethodsIn this study, the microbial community structure and function of FCT fermentated for 0–4 years were analyzed, and the changes of metabolites in tobacco leaves in different years were analyzed. …”
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Sentinel lymph nodes biopsy for malignant tumors using Technefit radioactive colloid Technetium 99mTc by Irina Onofriychuk, Aziz Zikiryahodzhaev, Anatoliy Ermakov, Nataliya Ablitsova, Eric Saribekyan, Elena Rasskazova, Gadgimurad Zapirov, Stanislav Mikhailov, Andrey Kaprin, Anna Sukhotko, Serghei Covantsev

“…Conclusion: We determined the most efficient dosages of activities, volume, and characteristics of radioactive colloid administration aimed at the examination and biopsy of sentinel lymph nodes using the radiopharmaceutical preparation Technefit 99mTc in patients with malignant tumors of different localizations, namely breast cancer and skin melanoma. …”
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